Page last updated: 2024-10-23

azathioprine and Head and Neck Neoplasms

azathioprine has been researched along with Head and Neck Neoplasms in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)

Research Excerpts

ExcerptRelevanceReference
"We report two cases of stage IV malignant melanoma arising in patients treated with azathioprine for myasthenia gravis."3.76Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review. ( Collichio, F; Dillon, P; Sharpless, N; Thomas, N, 2010)
"Excluding skin cancers, squamous cell carcinomas make up most head and neck cancers in transplant recipients."2.41Squamous cell carcinoma of the head and neck in solid organ transplant recipients. ( Adams, GL; Matas, A; Preciado, DA, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dillon, P1
Thomas, N1
Sharpless, N1
Collichio, F1
Kim, HK1
Jin, SY1
Lee, NS1
Won, JH1
Park, HS1
Yang, WI1
Muirhead, R1
Ritchie, DM1
Bottomley, WW1
Ford, G1
Cunliffe, WJ1
Cotterill, JA1
Veness, MJ1
López-Cepero Andrada, JM1
Ferré Alamo, A1
López Silva, M1
Salado Fuentes, M1
Benítez Roldán, A1
Preciado, DA1
Matas, A1
Adams, GL1
Dahlem, K1
Osterwald, L1

Reviews

1 review available for azathioprine and Head and Neck Neoplasms

ArticleYear
Squamous cell carcinoma of the head and neck in solid organ transplant recipients.
    Head & neck, 2002, Volume: 24, Issue:4

    Topics: Anti-Inflammatory Agents; Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Head and Neck Neopla

2002

Other Studies

7 other studies available for azathioprine and Head and Neck Neoplasms

ArticleYear
Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:4

    Topics: Aged; Azathioprine; Head and Neck Neoplasms; Humans; Immunosuppression Therapy; Immunosuppressive Ag

2010
Posttransplant primary cutaneous Ki-1 (CD30)+/CD56+ anaplastic large cell lymphoma.
    Archives of pathology & laboratory medicine, 2004, Volume: 128, Issue:8

    Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; CD4-Positive T-Lym

2004
Partial regression of Merkel cell carcinoma in response to withdrawal of azathioprine in an immunosuppression-induced case of metastatic Merkel cell carcinoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:1

    Topics: Azathioprine; Carcinoma, Merkel Cell; Fatal Outcome; Head and Neck Neoplasms; Humans; Immunocompromi

2007
Aggressive squamous cell carcinomas developing in patients receiving long-term azathioprine.
    The British journal of dermatology, 1995, Volume: 133, Issue:3

    Topics: Aged; Azathioprine; Carcinoma, Squamous Cell; Cocarcinogenesis; Ear Neoplasms; Head and Neck Neoplas

1995
Cardiac transplant-related cutaneous malignancies in an Australian recipient: immunosuppression, friend or foe?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1998, Volume: 10, Issue:3

    Topics: Adult; Australia; Azathioprine; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cy

1998
[Azathioprine and cavum carcinoma in a patient with autoimmune hepatitis and Crohn's disease].
    Gastroenterologia y hepatologia, 2001, Volume: 24, Issue:2

    Topics: Azathioprine; Carcinoma, Squamous Cell; Crohn Disease; Head and Neck Neoplasms; Hepatitis, Autoimmun

2001
[Examples for possible tumor induction by immunosuppressive and cytostatic drugs (case studies)].
    HNO, 1986, Volume: 34, Issue:8

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined

1986