azathioprine has been researched along with Granulocytic Leukemia in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A woman with relapsing-remitting multiple sclerosis (MS) was treated with oral azathioprine (AZA) for 4 years and subsequently switched to interferon-beta1a." | 7.73 | Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis. ( Al-Ali, HK; Niederwieser, D; Niklas, A; Schwarz, J; Strauss, A; Then Bergh, F; von Ahsen, N; Wagner, A, 2006) |
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 7.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| "A 66-year-old female with dermatomyositis (DM) who had received immunosuppressive therapy with azathioprine developed acute myeloid leukaemia (AML)." | 4.80 | Azathioprine-associated acute myeloid leukaemia with trilineage dysplasia and complex karyotype: a case report and review of the literature. ( Abdalla, SH; Arnold, JA; Ranson, SA, 1999) |
| "A woman with relapsing-remitting multiple sclerosis (MS) was treated with oral azathioprine (AZA) for 4 years and subsequently switched to interferon-beta1a." | 3.73 | Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis. ( Al-Ali, HK; Niederwieser, D; Niklas, A; Schwarz, J; Strauss, A; Then Bergh, F; von Ahsen, N; Wagner, A, 2006) |
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 3.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| " The patient presented is a 22-year-old white male who, following two renal transplants and prolonged immunosuppressive therapy with azathioprine and methylprednisolone, developed chronic granulocytic leukemia." | 3.66 | Chronic granulocytic leukemia following successful renal transplantation. ( Adler, KR; Lempert, N; Scharfman, WB, 1978) |
| "Chronic granulocytic leukemia (CGL) developed in a 31-year-old man after he underwent a third renal transplant." | 1.27 | Chronic granulocytic leukemia after renal transplantation. ( Didlake, R; Files, JC; Kirchner, KA; Krueger, RP; Raju, S, 1983) |
| "Chronic granulocytic leukemia developed four years after renal transplantation in a patient, who had been treated with immunosuppressive agents since then." | 1.26 | Chronic granulocytic leukemia in a renal transplant recipient. ( Hagenouw-Taal, JC; Lameijer, LD; Mooy, JM; van Turnhout, JM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (65.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Offman, J | 1 |
| Opelz, G | 1 |
| Doehler, B | 1 |
| Cummins, D | 1 |
| Halil, O | 1 |
| Banner, NR | 1 |
| Burke, MM | 1 |
| Sullivan, D | 1 |
| Macpherson, P | 1 |
| Karran, P | 1 |
| Then Bergh, F | 1 |
| Niklas, A | 1 |
| Strauss, A | 1 |
| von Ahsen, N | 1 |
| Niederwieser, D | 1 |
| Schwarz, J | 1 |
| Wagner, A | 1 |
| Al-Ali, HK | 1 |
| Kirchner, KA | 1 |
| Files, JC | 1 |
| Didlake, R | 1 |
| Raju, S | 1 |
| Krueger, RP | 1 |
| Vismans, JJ | 1 |
| Briët, E | 1 |
| Meijer, K | 1 |
| den Ottolander, GJ | 1 |
| Krishnan, K | 1 |
| Adams, P | 1 |
| Silveira, S | 1 |
| Sheldon, S | 1 |
| Dabich, L | 1 |
| Adams, GB | 1 |
| Lipton, JH | 1 |
| Jamal, N | 1 |
| Messner, HA | 1 |
| Subar, M | 1 |
| Gucalp, R | 1 |
| Benstein, J | 1 |
| Williams, G | 1 |
| Wiernik, PH | 1 |
| Kwong, YL | 1 |
| Au, WY | 1 |
| Liang, RH | 1 |
| Arnold, JA | 1 |
| Ranson, SA | 1 |
| Abdalla, SH | 1 |
| Mey, U | 1 |
| Franke, A | 1 |
| Fuchs, R | 1 |
| Mooy, JM | 1 |
| Hagenouw-Taal, JC | 1 |
| Lameijer, LD | 1 |
| van Turnhout, JM | 1 |
| Adler, KR | 1 |
| Lempert, N | 1 |
| Scharfman, WB | 1 |
| Stein, AM | 1 |
| Anthone, R | 1 |
| Anthone, S | 1 |
| Marinello, MJ | 1 |
| Elwood, CM | 1 |
| Bannerman, RM | 1 |
| Mocelin, AJ | 1 |
| Hager, ET | 1 |
| Carpenter, CB | 1 |
| Merrill, JP | 1 |
| Battin, J | 1 |
| Hehunstre, JP | 1 |
| Bui, NB | 1 |
| Auzerie, J | 1 |
| Colle, M | 1 |
| Patterson, R | 1 |
| Irons, JS | 1 |
| Kelly, JF | 1 |
| Mattson, JR | 1 |
| O, SH | 1 |
| Cobau, CD | 1 |
| Sheon, RP | 1 |
| Kirsner, AB | 1 |
| Hitchings, GH | 1 |
| Stacher, A | 1 |
| Böttcher, D | 1 |
| Maas, D | 1 |
| Wendt, F | 1 |
| Schubothe, H | 1 |
2 reviews available for azathioprine and Granulocytic Leukemia
| Article | Year |
|---|---|
Azathioprine-associated acute myeloid leukaemia with trilineage dysplasia and complex karyotype: a case report and review of the literature.
Topics: Acute Disease; Aged; Azathioprine; Dermatomyositis; Female; Humans; Immunosuppressive Agents; Leukem | 1999 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; | 1969 |
18 other studies available for azathioprine and Granulocytic Leukemia
| Article | Year |
|---|---|
Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation.
Topics: Acute Disease; Azathioprine; Base Pair Mismatch; Bone Marrow; DNA Repair; Follow-Up Studies; Heart T | 2004 |
Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis.
Topics: Acute Disease; Azathioprine; Disease Progression; Fatal Outcome; Female; Glatiramer Acetate; Humans; | 2006 |
Chronic granulocytic leukemia after renal transplantation.
Topics: Adult; Allopurinol; Azathioprine; Humans; Hydroxyurea; Kidney Transplantation; Leukemia, Myeloid; Ma | 1983 |
Azathioprine and subacute myelomonocytic leukemia.
Topics: Adult; Azathioprine; Bone Marrow; Female; Humans; Leukemia, Myeloid; Lupus Erythematosus, Systemic | 1980 |
Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis.
Topics: Acute Disease; Azathioprine; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, Pa | 1994 |
Allogeneic bone marrow transplantation from a related donor undergoing long-term immunosuppressive and cytotoxic therapy.
Topics: Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cy | 1994 |
Acute leukaemia following renal transplantation.
Topics: Acute Disease; Adult; Alkylating Agents; Azathioprine; Cyclophosphamide; Female; Humans; Immunosuppr | 1996 |
Acute myeloid leukemia after azathioprine treatment for autoimmune diseases: association with -7/7q-.
Topics: Acute Disease; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chromosomes, Human, Pair 7; Female; | 1998 |
[Acute mature myelocytic leukemia as a form of the myeloproliferative syndrome].
Topics: Acute Disease; Adult; Azathioprine; Bone Marrow Examination; Fetal Hemoglobin; Hematopoietic Stem Ce | 1979 |
Chronic granulocytic leukemia in a renal transplant recipient.
Topics: Azathioprine; Cadaver; Humans; Kidney Transplantation; Leukemia, Myeloid; Male; Middle Aged; Oncogen | 1978 |
Chronic granulocytic leukemia following successful renal transplantation.
Topics: Adult; Azathioprine; Cadaver; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Human | 1978 |
Chronic myelocytic leukemia in a young renal allografted patient.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Cytogenetics; Humans; Kidney Transplantation; Leu | 1978 |
[Medullar aplasia due to concomitant use of azathioprine and allopurinol in kidney transplantation. Probable beneficial effects of infusion of leukemic cells].
Topics: Adult; Allopurinol; Anemia, Aplastic; Azathioprine; Blood Transfusion; Drug Interactions; Humans; Ki | 1976 |
[Chronic myeloid leukemia after immunosuppressive treatment for chronic nephropathy].
Topics: Adolescent; Azathioprine; Glomerulonephritis; Humans; Leukemia, Myeloid; Male | 1976 |
Pulmonary infiltrates with eosinophilia.
Topics: Aspergillosis; Asthma; Azathioprine; Eosinophilia; Eosinophils; Humans; Leukemia, Myeloid; Lung Dise | 1974 |
Immunosuppressive drugs and acute leukemia.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Human | 1973 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; | 1970 |
[Anemia caused by erythroblastopenia in adult age].
Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti | 1970 |