Page last updated: 2024-10-23

azathioprine and Graft-Versus-Host Disease

azathioprine has been researched along with Graft-Versus-Host Disease in 42 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Three cases of nodular regenerative hyperplasia of the liver associated with azathioprine therapy are reported."8.78[Nodular regenerative hyperplasia of the liver associated with azathioprine therapy]. ( Dhumeaux, D; Duvoux, C; Kracht, M; Lang, P; Vernant, JP; Zafrani, ES, 1991)
"This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)."7.70Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000)
"Treatment with prednisone alone results in fewer infections and better survival than prednisone and azathioprine in standard-risk chronic GVHD."6.66Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. ( Appelbaum, FR; Dahlberg, S; Deeg, HJ; Doney, KC; Flournoy, N; Sanders, JE; Storb, R; Sullivan, KM; Weiden, P; Witherspoon, RP, 1988)
"Three cases of nodular regenerative hyperplasia of the liver associated with azathioprine therapy are reported."4.78[Nodular regenerative hyperplasia of the liver associated with azathioprine therapy]. ( Dhumeaux, D; Duvoux, C; Kracht, M; Lang, P; Vernant, JP; Zafrani, ES, 1991)
"This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)."3.70Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000)
"Treatment with prednisone alone results in fewer infections and better survival than prednisone and azathioprine in standard-risk chronic GVHD."2.66Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. ( Appelbaum, FR; Dahlberg, S; Deeg, HJ; Doney, KC; Flournoy, N; Sanders, JE; Storb, R; Sullivan, KM; Weiden, P; Witherspoon, RP, 1988)
"The renal biopsy showed type I membranoproliferative glomerulonephritis."1.36Membranoproliferative glomerulonephritis following allogeneic hematopoietic stem cell transplantation. ( Chang, YS; Chung, S; Kim, B; Kim, JY; Lee, MY; Park, CW, 2010)
"A 26-year-old male with acute lymphoblastic leukemia (ALL) in its second complete remission received an unrelated bone marrow transplantation (UBMT) following cyclophosphamide plus total body irradiation conditioning."1.31A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT. ( Nakaseko, C; Nishimura, M; Saito, Y; Uehara, T; Yokota, A, 2002)
" The lower variability of trough levels and the higher L/D ratio in the CyE group, which are related ti improved bioavailability of CyE, may explain the lower rejection rate among these patients."1.30Comparison of Neoral and Sandimmun for induction and maintenance immunosuppression after kidney transplantation. ( Haberal, M; Karakayali, H; Moray, G; Senel, FM; Yildirim, S, 1997)
" Throughout the dosing interval, the enzyme activities parallel the respective drug concentrations."1.30Pharmacodynamic monitoring of immunosuppressive drugs. ( Aspeslet, LJ; Gallant, HL; Yatscoff, RW, 1998)
"Detection of the chronic myelogenous leukemia (CML)-related marker, the bcr/abl m-RNA transcript, in blood or bone marrow of patients with CML in hematologic remission after allogeneic bone marrow transplantation (allo-BMT) may be associated with the presence of minimal residual disease but does not uniformly predict hematologic relapse."1.29Case report of spontaneous remission of cytogenetic relapse of chronic myelogenous leukemia suggestive of progression to blast crisis after allogeneic bone marrow transplantation. ( Agaliotis, DP; Elfenbein, GJ; Moscinski, LC; Papenhausen, PR, 1995)
"Thalidomide treatment was successful in the majority of animals (16 of 18)."1.28Therapy of chronic graft-v-host disease in a rat model. ( Friedman, KJ; Hess, AD; Santos, GW; Vogelsang, GB, 1989)
" Although one patient subsequently required chronic dialysis, reduction of cyclosporine dosage from a mean of 5."1.27Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients. ( Bahnson, HT; Bernstein, RL; Egel, JW; Greenberg, A; Griffith, BP; Hardesty, RL; Hastillo, A; Hess, ML; Puschett, JB; Thompson, ME, 1987)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199020 (47.62)18.7374
1990's9 (21.43)18.2507
2000's9 (21.43)29.6817
2010's4 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uhm, J1
Shin, E1
Michelis, FV1
Thyagu, S1
Viswabandya, A1
Lipton, JH2
Messner, HA2
Kim, DDH1
Chien, SH1
Liu, CJ1
Hong, YC1
Teng, CJ1
Hu, YW1
Shen, CC1
Ku, FC1
Chen, SC1
Yeh, CM1
Chiou, TJ1
Gau, JP1
Tzeng, CH1
Fix, OK1
Stock, PG1
Lee, BK1
Benson, MD1
Kim, JY1
Lee, MY1
Kim, B1
Park, CW1
Chang, YS1
Chung, S1
Uehara, T1
Nakaseko, C1
Yokota, A1
Saito, Y1
Nishimura, M1
Sasaki, M1
Fujiyama, Y1
Gaziev, J1
Sodani, P1
Polchi, P1
Andreani, M1
Lucarelli, G1
Lin, PC1
Hsiao, LT1
Chen, PM1
Habib, S1
Nalesnik, MA1
Ahmad, J1
BuchBarker, D1
Shakil, AO1
Reményi, P1
Masszi, T1
Borbényi, Z1
Soós, J1
Siklós, L1
Engelhardt, JI1
Castro, LA1
Eigler, J1
Land, W1
Cohen, DJ1
Loertscher, R1
Rubin, MF1
Tilney, NL1
Carpenter, CB1
Strom, TB1
Tampi, R1
Barr, AL1
Zilko, PJ1
Kanamaru, A1
Takemoto, Y1
Kakishita, E1
Dohy, H1
Kodera, Y1
Moriyama, Y1
Shibata, A1
Kasai, M1
Katoh, S1
Saitoh, H1
Agaliotis, DP1
Papenhausen, PR1
Moscinski, LC1
Elfenbein, GJ1
Adams, GB1
Jamal, N1
Yaron, I1
Yaron, R1
Oluwole, SF1
Hardy, MA1
Gruessner, RW1
Fasola, C1
Fryer, J1
Nakhleh, RE1
Kim, S1
Gruessner, AC1
Beebe, D1
Moon, C1
Troppmann, C1
Najarian, JS1
Senel, FM1
Yildirim, S1
Karakayali, H1
Moray, G1
Haberal, M1
Yatscoff, RW1
Aspeslet, LJ1
Gallant, HL1
Epstein, JB2
Nantel, S2
Sheoltch, SM1
Gorsky, M1
Epstein, MS1
Maury, S1
Mary, JY1
Rabian, C1
Schwarzinger, M1
Toubert, A1
Scieux, C1
Carmagnat, M1
Esperou, H1
Ribaud, P1
Devergie, A1
Guardiola, P1
Vexiau, P1
Charron, D1
Gluckman, E1
Socié, G1
Alsina, AE1
Nagashima, I1
Schweizer, RT1
Duvoux, C1
Kracht, M1
Lang, P1
Vernant, JP2
Zafrani, ES1
Dhumeaux, D1
Appleby, P1
Webber, DG1
Bowen, JG1
Wingard, JR1
Piantadosi, S1
Vogelsang, GB2
Farmer, ER1
Jabs, DA1
Levin, LS1
Beschorner, WE1
Cahill, RA1
Miller, DF1
Harrison, D1
Sullivan, KM2
Buckner, CD1
Sanders, JE2
Anasetti, C1
Appelbaum, FR2
Clark, J1
Doney, K1
Meyers, J1
Sale, G1
Storb, R2
Hess, AD1
Friedman, KJ1
Santos, GW1
Witherspoon, RP1
Weiden, P1
Flournoy, N1
Dahlberg, S1
Deeg, HJ1
Doney, KC1
Marit, G1
Maraninchi, D1
Guyotat, D1
Kuentz, M1
Cordonnier, C1
Reiffers, J1
Greenberg, A1
Egel, JW1
Thompson, ME1
Hardesty, RL1
Griffith, BP1
Bahnson, HT1
Bernstein, RL1
Hastillo, A1
Hess, ML1
Puschett, JB1
First, LR1
Smith, BR1
Lipton, J1
Nathan, DG1
Parkman, R1
Rappeport, JM1
Pichlmaier, H1
Kline, TS1
Craighead, JE1
Häyry, P1
Lalla, M1
Pasternack, A1
Virolainen, M1
Husberg, B1
Carlsson, S1
Hellsten, S1
Liedberg, CF1
Nettelblad, SC1
Weiber, A1
Ota, K1
Mori, S1
Inou, T1
Kanazawa, Y1
Kuzuya, T1
Kalter, SS1
Ratner, IA1
Britton, HA1
Vice, TE1
Eugster, AK1
Rodriguez, AR1
DeKlerk, JN1
Murphy, GP1
Van Zyl, JJ1
Van Zyl, JA1
Weber, HW1
Brede, HD1
Scott, WW1
Levitt, SH1
Royster, RL1
O'Foughludha, FT1
Wolf, JS1
Lower, RR1
King, ER1
DeGiorgi, LS1
Namba, T1
Arimori, S1
Grob, D1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Belumosudil and Rituximab for the Primary Treatment of Extensive Chronic Graft-versus-host Disease[NCT06046248]Phase 225 participants (Anticipated)Interventional2023-12-31Not yet recruiting
Azacitidine (AZA) Combined With N-Acetyl-L-cysteine (NAC) for Prolonged Isolated Thrombocytopenia (PIT) After Hematopoietic Stem Cell Transplantation (HSCT)[NCT05126004]Phase 2100 participants (Anticipated)Interventional2021-12-01Not yet recruiting
A Prospective Study of Patients With Isolated Thrombocytopenia Following Hematopoietic Stem Cell Transplantation[NCT02487563]Phase 397 participants (Actual)Interventional2015-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Megakaryocyte Count

The total number of megakaryocytes as well as the platelet-shedding megakaryocytes of bone marrow smears (per cm2) was counted and cross-checked by blinded observers. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment

Interventioncells/cm^2 (Median)
Experimental Group 16.7
Experimental Group 27.5
Control Group3.3

Number of Participants With Platelet Count Recovery

Platelet response refers to a sustained increase (stable or increasing level) of at least 30×10E9/L independent of transfusion for 3 days. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment

InterventionParticipants (Count of Participants)
Experimental Group 120
Experimental Group 222
Control Group6

Reviews

5 reviews available for azathioprine and Graft-Versus-Host Disease

ArticleYear
[Azathioprine].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 5

    Topics: Apoptosis; Azathioprine; CD28 Antigens; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combinatio

2005
[After care of kidney transplant patients].
    Der Internist, 1983, Volume: 24, Issue:9

    Topics: Adrenal Cortex Hormones; Aftercare; Antilymphocyte Serum; Azathioprine; Cyclosporins; Graft Rejectio

1983
Cyclosporine: a new immunosuppressive agent for organ transplantation.
    Annals of internal medicine, 1984, Volume: 101, Issue:5

    Topics: Animals; Azathioprine; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Cyclospo

1984
[Nodular regenerative hyperplasia of the liver associated with azathioprine therapy].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:12

    Topics: Adult; Azathioprine; Graft vs Host Disease; Humans; Hyperplasia; Hypertension, Portal; Immunosuppres

1991
Long-term complications of bone marrow transplantation.
    Progress in clinical and biological research, 1989, Volume: 309

    Topics: Azathioprine; Bone Marrow Transplantation; Chronic Disease; Graft vs Host Disease; Humans; Prednison

1989

Trials

2 trials available for azathioprine and Graft-Versus-Host Disease

ArticleYear
FK506 treatment of graft-versus-host disease developing or exacerbating during prophylaxis and therapy with cyclosporin and/or other immunosuppressants. Japanese FK506 BMT Study Group.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Child; Chronic Disease;

1995
Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation.
    Blood, 1988, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disea

1988

Other Studies

35 other studies available for azathioprine and Graft-Versus-Host Disease

ArticleYear
Therapeutic efficacy of azathioprine in addition to prednisone-based regimens as first-line chronic graft-versus-host disease treatment.
    Bone marrow transplantation, 2018, Volume: 53, Issue:3

    Topics: Adult; Aged; Azathioprine; Canada; Chronic Disease; Drug Therapy, Combination; Female; Graft vs Host

2018
Use of azathioprine for graft-vs-host disease is the major risk for development of secondary malignancies after haematopoietic stem cell transplantation: a nationwide population-based study.
    British journal of cancer, 2015, Jan-06, Volume: 112, Issue:1

    Topics: Adult; Azathioprine; Cohort Studies; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transpla

2015
Liver transplant alone without kidney transplant for fibrinogen Aα-chain (AFib) renal amyloidosis.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2016, Volume: 23, Issue:2

    Topics: Amyloidosis; Azathioprine; Creatinine; Female; Fibrinogen; Gene Expression; Genes, Dominant; Graft v

2016
Membranoproliferative glomerulonephritis following allogeneic hematopoietic stem cell transplantation.
    Clinical and experimental nephrology, 2010, Volume: 14, Issue:6

    Topics: Adult; Azathioprine; Glomerulonephritis, Membranoproliferative; Graft vs Host Disease; Hematopoietic

2010
A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT.
    American journal of hematology, 2002, Volume: 71, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azathioprine; Bone Marrow Trans

2002
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical

2005
Acute graft-versus-host disease of the lung with atypical presentation.
    International journal of hematology, 2006, Volume: 84, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents; Azathioprine; Graft vs Host Disease; Hematopoietic Stem Cel

2006
Alloimmune hepatitis following peripheral stem cell transplantation.
    Bone marrow transplantation, 2007, Volume: 39, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Busulfan; Cyclophosphamide; Female; Graft vs Host Dis

2007
CIDP cured by allogeneic hematopoietic stem cell transplantation.
    European journal of neurology, 2007, Volume: 14, Issue:8

    Topics: Adult; Alopecia; Anemia, Aplastic; Azathioprine; Cyclophosphamide; Female; Graft vs Host Disease; He

2007
Case report. Successful treatment of chronic cutaneous graft-versus-host-disease (GVHD) with penicillamine.
    Clinical and laboratory haematology, 1984, Volume: 6, Issue:4

    Topics: Adult; Azathioprine; Graft vs Host Disease; Humans; Male; Penicillamine; Prednisolone

1984
Case report of spontaneous remission of cytogenetic relapse of chronic myelogenous leukemia suggestive of progression to blast crisis after allogeneic bone marrow transplantation.
    Annals of hematology, 1995, Volume: 70, Issue:1

    Topics: Adult; Azathioprine; Blast Crisis; Bone Marrow Transplantation; Female; Graft vs Host Disease; Human

1995
Allogeneic bone marrow transplantation from a related donor undergoing long-term immunosuppressive and cytotoxic therapy.
    Bone marrow transplantation, 1994, Volume: 13, Issue:6

    Topics: Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cy

1994
UVB irradiation of human-derived peripheral blood lymphocytes induces apoptosis but not T-cell anergy: additive effects with various immunosuppressive agents.
    Cellular immunology, 1996, Mar-15, Volume: 168, Issue:2

    Topics: Apoptosis; Azathioprine; Clonal Anergy; Cyclosporine; Cytotoxicity, Immunologic; DNA Damage; Graft v

1996
Quadruple immunosuppression in a pig model of small bowel transplantation.
    The Journal of surgical research, 1996, Feb-15, Volume: 61, Issue:1

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Graft R

1996
Comparison of Neoral and Sandimmun for induction and maintenance immunosuppression after kidney transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1997, Volume: 10, Issue:5

    Topics: Azathioprine; Biological Availability; Cyclosporine; Drug Delivery Systems; Emulsions; Graft vs Host

1997
Pharmacodynamic monitoring of immunosuppressive drugs.
    Clinical chemistry, 1998, Volume: 44, Issue:2

    Topics: Azathioprine; Calcineurin; Cyclosporine; Drug Monitoring; Graft vs Host Disease; Humans; Immunosuppr

1998
Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease.
    Bone marrow transplantation, 2000, Volume: 25, Issue:6

    Topics: Administration, Topical; Adult; Anemia, Aplastic; Azathioprine; Bone Marrow Transplantation; Candidi

2000
Topical azathioprine in the treatment of immune-mediated chronic oral inflammatory conditions: a series of cases.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2001, Volume: 91, Issue:1

    Topics: Adult; Autoimmune Diseases; Azathioprine; Chronic Disease; Erythema; Female; Gels; Graft vs Host Dis

2001
Prolonged immune deficiency following allogeneic stem cell transplantation: risk factors and complications in adult patients.
    British journal of haematology, 2001, Volume: 115, Issue:3

    Topics: Adolescent; Adult; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocyt

2001
Orthotopic porcine small bowel transplantation using low-dose cyclosporine in triple immunosuppressive therapy.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Azathioprine; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Graft Survival; Gra

1992
Murine chronic graft-versus-host disease as a model of systemic lupus erythematosus: effect of immunosuppressive drugs on disease development.
    Clinical and experimental immunology, 1989, Volume: 78, Issue:3

    Topics: Animals; Azathioprine; Cyclophosphamide; Cyclosporins; Deoxyguanosine; Dexamethasone; Disease Models

1989
Predictors of death from chronic graft-versus-host disease after bone marrow transplantation.
    Blood, 1989, Volume: 74, Issue:4

    Topics: Actuarial Analysis; Adolescent; Adult; Analysis of Variance; Azathioprine; Bone Marrow Transplantati

1989
Therapy of chronic graft-v-host disease in a rat model.
    Blood, 1989, Volume: 74, Issue:1

    Topics: Animals; Azathioprine; Cyclosporins; Disease Models, Animal; Drug Synergism; Graft vs Host Disease;

1989
Allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia in first complete remission.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Graft vs Host Disease; Humans; Leukemi

1988
Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1987, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Adult; Azathioprine; beta 2-Microglobulin; Cardiopulmonary Bypass; Cyclosporins

1987
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
    Blood, 1985, Volume: 65, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child

1985
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
    Blood, 1985, Volume: 65, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child

1985
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
    Blood, 1985, Volume: 65, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child

1985
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
    Blood, 1985, Volume: 65, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child

1985
[Clinical picture of kidney transplantation. Surgical report].
    Langenbecks Archiv fur Chirurgie, 1968, Volume: 322

    Topics: Antilymphocyte Serum; Azathioprine; Cadaver; Dactinomycin; Gastrointestinal Hemorrhage; Graft vs Hos

1968
Renal homotransplantation. The cytology of the urine sediment.
    American journal of clinical pathology, 1967, Volume: 47, Issue:6

    Topics: Adrenal Cortex Hormones; Azaserine; Azathioprine; Cytomegalovirus Infections; Dactinomycin; Graft vs

1967
Proliferation of white blood cells in the blood of human renal allograft recipients. Lack of correlation with acute rejection episodes.
    Annals of clinical research, 1972, Volume: 4, Issue:2

    Topics: Adult; Autoradiography; Azathioprine; Cell Division; Child; DNA; Erythrocytes; Female; Graft Rejecti

1972
Antilymphocyte globulin prepared by precipitation with Rivanol in the treatment of acute rejection following allogenic renal transplantation in the dog.
    Scandinavian journal of urology and nephrology, 1972, Volume: 6, Issue:2

    Topics: Acridines; Animals; Antilymphocyte Serum; Azathioprine; Chemical Precipitation; Creatinine; Dogs; Gr

1972
Endocrine function of the pancreatic allograft.
    Endocrinology, 1968, Volume: 82, Issue:4

    Topics: Animals; Azathioprine; Blood Glucose; Dogs; Glucose Tolerance Test; Graft vs Host Disease; Hyperglyc

1968
Wasting syndrome in thymectomized immature baboons (papio species) after infection with adenovirus type 12.
    Nature, 1967, Feb-11, Volume: 213, Issue:5076

    Topics: Adenoviridae; Alopecia; Animals; Antibody Formation; Azathioprine; Body Weight; Cobalt Isotopes; Com

1967
New methods of treatment for renal allotransplants using the baboon as a primate experimental model.
    The Journal of urology, 1969, Volume: 102, Issue:5

    Topics: Animals; Antibodies; Azathioprine; Cyclophosphamide; Female; Globulins; Graft vs Host Disease; Haplo

1969
Radiation for immunosuppression in human organ transplantation. II. Clinical experience.
    Acta radiologica: therapy, physics, biology, 1971, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Animals; Antilymphocyte Serum; Azathioprine; Blood; Cadaver; Child; Dogs; Extraco

1971
Effect on mice of intravenous administration of lymphocytes from normal subjects and from patients with myasthenia gravis.
    Neurology, 1969, Volume: 19, Issue:5

    Topics: Adult; Animals; Azathioprine; Female; Graft vs Host Disease; Growth; Humans; Injections, Intravenous

1969