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azathioprine and Fractures, Bone

azathioprine has been researched along with Fractures, Bone in 4 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Fractures, Bone: Breaks in bones.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine was associated with an increase in overall fracture risk, but besides this, none of the drugs was significantly associated with overall fracture risk or risk of hip, spine, or forearm fracture."1.33Methotrexate, azathioprine, cyclosporine, and risk of fracture. ( Mosekilde, L; Rejnmark, L; Vestergaard, P, 2006)
"Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors."1.31Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prasad, R1
De Silva, M1
Sprague, SM1
Josephson, MA1
Vestergaard, P1
Rejnmark, L1
Mosekilde, L1
Patel, S1
Kwan, JT1
McCloskey, E1
McGee, G1
Thomas, G1
Johnson, D1
Wills, R1
Ogunremi, L1
Barron, J1

Reviews

1 review available for azathioprine and Fractures, Bone

ArticleYear
Bone disease after kidney transplantation.
    Seminars in nephrology, 2004, Volume: 24, Issue:1

    Topics: Azathioprine; Bone Density; Bone Diseases; Calcifediol; Cyclosporine; Fractures, Bone; Graft Rejecti

2004

Other Studies

3 other studies available for azathioprine and Fractures, Bone

ArticleYear
Osteoporosis with underlying connective tissue disease: an unusual case.
    Annals of the New York Academy of Sciences, 2002, Volume: 966

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant

2002
Methotrexate, azathioprine, cyclosporine, and risk of fracture.
    Calcified tissue international, 2006, Volume: 79, Issue:2

    Topics: Adult; Aged; Azathioprine; Case-Control Studies; Cyclosporine; Enzyme Inhibitors; Female; Fractures,

2006
Prevalence and causes of low bone density and fractures in kidney transplant patients.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Back Pain; Biomarkers; Bone Density; Cyclo

2001