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azathioprine and Focal Segmental Glomerulosclerosis

azathioprine has been researched along with Focal Segmental Glomerulosclerosis in 29 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the effects of losartan on proteinuria and renal function in patients with FSGS refractory to immunosuppressive treatment."9.10Efficacy of losartan in patients with primary focal segmental glomerulosclerosis resistant to immunosuppressive treatment. ( Dilek, K; Ersoy, A; Güllülü, M; Ozdemir, B; Usta, M; Yavuz, M; Yurtkuran, M, 2003)
"Nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) is a common cause of renal failure leading to transplantation."5.29Effects of cyclosporine, azathioprine and prednisone on Kimura's disease and focal segmental glomerulosclerosis in renal transplant patients. ( Barcenas, C; Etheridge, WB; Jammal, C; Kahan, BD; Senel, MF; Van Buren, CT, 1996)
" The aim of this study was to evaluate the effects of losartan on proteinuria and renal function in patients with FSGS refractory to immunosuppressive treatment."5.10Efficacy of losartan in patients with primary focal segmental glomerulosclerosis resistant to immunosuppressive treatment. ( Dilek, K; Ersoy, A; Güllülü, M; Ozdemir, B; Usta, M; Yavuz, M; Yurtkuran, M, 2003)
"To suppress the activity of glomerulonephritis, lupus and primary chronic mixed one, 13 children received plasmapheresis synchronously with pulse therapy with cyclophosphamide or prednisolone."5.07[Synchronization of plasmapheresis and pulse therapy in the complex treatment of children with highly active glomerulonephritis]. ( Donov, GI; Fomenko, TM; Kartasheva, VI; Klimov, IuV; Osminina, MK, 1991)
"Prednisolone alone was followed by remission of nephrotic syndrome in 62."2.72Immunosuppressive treatment of idiopathic focal segmental glomerulosclerosis: a five-year follow-up study. ( Brown, CB; Davlouros, P; El Nahas, AM; Goumenos, DS; Shortland, JR; Tsagalis, G; Vlachojannis, JG, 2006)
" The renal tolerability of CsA is reasonably good when the dosage is low."2.43Treatment of focal segmental glomerulosclerosis. ( Meyrier, A, 2005)
"LON was not observed in minimal change disease or focal segmental glomerulosclerosis."1.62Incidence, Clinical Features, and Outcomes of Late-Onset Neutropenia From Rituximab for Autoimmune Disease. ( Cortazar, FB; Huizenga, NR; Laliberte, K; Niles, JL; Rhee, EP; Rosenthal, JM; Wallace, ZS; Zonozi, R, 2021)
"Eighty nephrotic adults with focal segmental glomerulosclerosis (FSGS) and plasma creatinine lower than 3 mg/dL were given corticosteroids (53 patients) or immunosuppressive agents (27 patients) for a median of 16 and 75 weeks, respectively."1.30Can prolonged treatment improve the prognosis in adults with focal segmental glomerulosclerosis? ( Banfi, G; Baroli, A; Cesana, B; Farina, M; Grassi, C; Pani, A; Passerini, P; Ponticelli, C; Pozzi, C; Villa, M, 1999)
"Nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) is a common cause of renal failure leading to transplantation."1.29Effects of cyclosporine, azathioprine and prednisone on Kimura's disease and focal segmental glomerulosclerosis in renal transplant patients. ( Barcenas, C; Etheridge, WB; Jammal, C; Kahan, BD; Senel, MF; Van Buren, CT, 1996)
"End-stage renal disease (ESRD) was secondary to chronic glomerulonephritis (n = 9), diabetes mellitus (n = 6), polycystic kidney disease (n = 5), and miscellaneous causes (n = 11)."1.28The development of proteinuria and focal-segmental glomerulosclerosis in recipients of pediatric donor kidneys. ( Hayes, JM; Novick, AC; Steinmuller, DR; Streem, SB, 1991)
"To evaluate the rate of recurrence of focal segmental glomerulosclerosis (FSGS) in renal transplant patients treated with cyclosporine, we reviewed the outcome of 25 renal Tx performed in 24 patients who had FSGS as their original renal disease."1.28The recurrence of focal segmental glomerulosclerosis in kidney transplant patients treated with cyclosporine. ( Banfi, G; Colturi, C; Montagnino, G; Ponticelli, C, 1990)
"Focal segmental glomerulosclerosis was diagnosed by strict histologic criteria in 103 patients."1.27Evidence suggesting under-treatment in adults with idiopathic focal segmental glomerulosclerosis. Regional Glomerulonephritis Registry Study. ( Cattran, D; Delmore, T; Katz, A; Lang, A; Pei, Y; Rance, P, 1987)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199010 (34.48)18.7374
1990's6 (20.69)18.2507
2000's9 (31.03)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Zonozi, R1
Wallace, ZS1
Laliberte, K1
Huizenga, NR1
Rosenthal, JM1
Rhee, EP1
Cortazar, FB1
Niles, JL1
Koratala, A1
Kazory, A1
Bui, T1
Chandrakasan, S1
Poulik, J1
Fathalla, BM1
MacIver, H1
Hordon, L1
Pham, PT1
Pham, PC1
Usta, M1
Ersoy, A1
Dilek, K1
Ozdemir, B1
Yavuz, M1
Güllülü, M1
Yurtkuran, M1
Korkmaz, C1
Kabukcuoğlu, S1
Isiksoy, S1
Yalçin, AU1
Manrique, J1
Rossich, E1
Hernández Sierra, A1
Meyrier, A1
Goumenos, DS1
Tsagalis, G1
El Nahas, AM1
Shortland, JR1
Davlouros, P1
Vlachojannis, JG1
Brown, CB1
Stirling, CM1
Kuhn, C1
Kuhn, A1
Markau, S1
Kästner, U1
Osten, B1
Ponticelli, C3
Banfi, G3
Imbasciati, E1
Tarantino, A1
Donadio, JV1
Senel, MF1
Van Buren, CT1
Etheridge, WB1
Barcenas, C1
Jammal, C1
Kahan, BD1
Klein, M1
Radhakrishnan, J1
Appel, G1
Villa, M1
Cesana, B1
Pozzi, C1
Pani, A1
Passerini, P1
Farina, M1
Grassi, C1
Baroli, A1
Hamar, P1
Liu, S1
Viklický, O1
Szabó, A1
Múller, V1
Heemann, U1
Simon, NM1
Rosenberg, MJ1
Beirne, GJ1
Wagnild, JP1
Zimmerman, SW1
Macken, PD1
Burkholder, PM1
Kartasheva, VI1
Donov, GI1
Fomenko, TM1
Klimov, IuV1
Osminina, MK1
Hayes, JM1
Steinmuller, DR1
Streem, SB1
Novick, AC1
Colturi, C1
Montagnino, G1
ter Borg, EJ1
Tervaert, JW1
Hollema, H1
de Jong, PE1
Kallenberg, CG1
Pei, Y1
Cattran, D1
Delmore, T1
Katz, A1
Lang, A1
Rance, P1
Belovezhdov, N2
White, RH1
Glasgow, EF1
Mills, RJ1
Cameron, JS1
Ogg, CS1
Turner, DR1
Weller, RO1

Reviews

4 reviews available for azathioprine and Focal Segmental Glomerulosclerosis

ArticleYear
Treatment of focal segmental glomerulosclerosis.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:9

    Topics: Alkylating Agents; Antimetabolites; Azathioprine; Contraindications; Cyclophosphamide; Cyclosporine;

2005
Immunosuppressive therapy in primary glomerulonephritis (pros).
    Contributions to nephrology, 1982, Issue:34

    Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulone

1982
Cyclosporine treatment of glomerular diseases.
    Annual review of medicine, 1999, Volume: 50

    Topics: Autoimmune Diseases; Azathioprine; Cyclosporine; Drug Combinations; Glomerulonephritis; Glomerulonep

1999
Medical treatment of glomerular diseases.
    The Medical clinics of North America, 1978, Volume: 62, Issue:6

    Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Child; Chlorambucil; Cyclophosphamid

1978

Trials

3 trials available for azathioprine and Focal Segmental Glomerulosclerosis

ArticleYear
Efficacy of losartan in patients with primary focal segmental glomerulosclerosis resistant to immunosuppressive treatment.
    Journal of internal medicine, 2003, Volume: 253, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Antihypertensive Agents; Azathioprine; Blood Pressure; Cyclophospham

2003
Immunosuppressive treatment of idiopathic focal segmental glomerulosclerosis: a five-year follow-up study.
    Nephron. Clinical practice, 2006, Volume: 104, Issue:2

    Topics: Adult; Azathioprine; Cyclosporine; Drug Combinations; Female; Follow-Up Studies; Glomerulosclerosis,

2006
[Synchronization of plasmapheresis and pulse therapy in the complex treatment of children with highly active glomerulonephritis].
    Pediatriia, 1991, Issue:7

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chronic Disease; Combined Modality Therapy; Cyclo

1991

Other Studies

22 other studies available for azathioprine and Focal Segmental Glomerulosclerosis

ArticleYear
Incidence, Clinical Features, and Outcomes of Late-Onset Neutropenia From Rituximab for Autoimmune Disease.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:2

    Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Asymptomatic Diseases; Auto

2021
Renal Revival: The Hidden Benefit of Antirejection Medications.
    Transplantation, 2018, Volume: 102, Issue:11

    Topics: Adult; Azathioprine; Drug Administration Schedule; Drug Therapy, Combination; Glomerulosclerosis, Fo

2018
Granulomatosis with polyangiitis presenting as Henoch-Schönlein purpura in children.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2013, Volume: 19, Issue:4

    Topics: Abdominal Pain; Anti-Infective Agents; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Child;

2013
An unusual case of testicular pain.
    Clinical rheumatology, 2009, Volume: 28, Issue:3

    Topics: Administration, Oral; Adult; Azathioprine; Diagnosis, Differential; Diuretics; Drug Therapy, Combina

2009
The impact of mycophenolate mofetil versus azathioprine as adjunctive therapy to cyclosporine on the rates of renal allograft loss due to glomerular disease recurrence.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtratio

2012
Renal involvement in primary antiphospholipid syndrome and its response to immunosuppressive therapy.
    Lupus, 2003, Volume: 12, Issue:10

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Azathioprine; Female; Glomeruloscler

2003
[Multiple complications after renal transplantation].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Adult; Azathioprine; Cataract; Cholecystitis; Choledocholithiasis; Cyclosporine; Femur Head Necrosis

2004
Focal segmental glomerulosclerosis--does treatment work?
    Nephron. Clinical practice, 2006, Volume: 104, Issue:2

    Topics: Azathioprine; Clinical Trials as Topic; Cyclosporine; Drug Combinations; Evidence-Based Medicine; Gl

2006
Effect of immunoadsorption on refractory idiopathic focal and segmental glomerulosclerosis.
    Journal of clinical apheresis, 2006, Volume: 21, Issue:4

    Topics: Adult; Anemia, Megaloblastic; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
Primary glomerular disease: to treat or not to treat.
    Contributions to nephrology, 1982, Volume: 33

    Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulonephritis; Glomerulosclerosis,

1982
Effects of cyclosporine, azathioprine and prednisone on Kimura's disease and focal segmental glomerulosclerosis in renal transplant patients.
    Clinical nephrology, 1996, Volume: 45, Issue:1

    Topics: Adult; Angiolymphoid Hyperplasia with Eosinophilia; Azathioprine; Cyclosporine; Glomerulosclerosis,

1996
Can prolonged treatment improve the prognosis in adults with focal segmental glomerulosclerosis?
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 34, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Dr

1999
Cyclosporine A and azathioprine are equipotent in chronic kidney allograft rejection.
    Transplantation, 2000, Apr-15, Volume: 69, Issue:7

    Topics: Animals; Azathioprine; Chronic Disease; Cyclosporine; Glomerulosclerosis, Focal Segmental; Graft Rej

2000
Idiopathic crescentic glomerulonephritis.
    Medicine, 1977, Volume: 56, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Antibodies; Azathioprine; Basement Membrane; Female; Glomerulo

1977
The development of proteinuria and focal-segmental glomerulosclerosis in recipients of pediatric donor kidneys.
    Transplantation, 1991, Volume: 52, Issue:5

    Topics: Adult; Age Factors; Antilymphocyte Serum; Azathioprine; Child, Preschool; Creatinine; Cyclosporine;

1991
The recurrence of focal segmental glomerulosclerosis in kidney transplant patients treated with cyclosporine.
    Transplantation, 1990, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Age Factors; Azathioprine; Child; Child, Preschool; Cyclosporins; Female; Glomeru

1990
[A patient with recurrent polychondritis, vasculitis and local focal glomerulonephritis].
    Nederlands tijdschrift voor geneeskunde, 1988, Mar-26, Volume: 132, Issue:13

    Topics: Azathioprine; Drug Therapy, Combination; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hu

1988
Evidence suggesting under-treatment in adults with idiopathic focal segmental glomerulosclerosis. Regional Glomerulonephritis Registry Study.
    The American journal of medicine, 1987, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Female; Follow-Up Studie

1987
[Differentiated pathogenetic therapy of glomerulonephritis].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:8

    Topics: Adrenal Cortex Hormones; Anticoagulants; Azathioprine; Chronic Disease; Drug Evaluation; Drug Therap

1987
[Possibilities for treating patients with the idiopathic nephrotic syndrome].
    Vutreshni bolesti, 1985, Volume: 24, Issue:4

    Topics: Acenocoumarol; Adolescent; Adult; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Female;

1985
Focal glomerulosclerosis in childhood.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 1

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Atrophy; Azathioprine; Basement Membrane; Biopsy;

1973
Focal glomerulosclerosis.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyc

1973