azathioprine has been researched along with Focal Nodular Hyperplasia in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Focal Nodular Hyperplasia: Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. The nodule, poorly encapsulated, consists of a central stellate fibrous scar and normal liver elements such as HEPATOCYTES, small BILE DUCTS, and KUPFFER CELLS among the intervening fibrous septa. The pale colored central scar represents large blood vessels with hyperplastic fibromuscular layer and narrowing lumen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancytopenia was most likely azathioprine-related." | 3.74 | [Nodular regenerative hyperplasia as a side effect of azathioprine in a patient with Crohn's disease]. ( Günther, U; Loddenkemper, C; Preiss, JC; Schumann, M; Siegmund, B; Somasundaram, R; Zeitz, M, 2008) |
| "Purine analogues are major drugs in the treatment of inflammatory bowel diseases (IBD)." | 1.33 | Azathioprine induced nodular regenerative hyperplasia in IBD patients. ( Cadranel, JF; Cazier, A; Coutarel, P; Daniel, F; Duong Van Huyen, JP; Jian, R; Loison, P; Marteau, P; Seksik, P; Ziol, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| León-Montañes, R | 1 |
| Trigo-Salado, C | 1 |
| Leo-Carnerero, E | 1 |
| de-la-Cruz-Ramírez, MD | 1 |
| Herrera-Justiniano, JM | 1 |
| Márquez-Galán, JL | 1 |
| Musumba, CO | 1 |
| Schumann, M | 1 |
| Preiss, JC | 1 |
| Loddenkemper, C | 1 |
| Günther, U | 1 |
| Somasundaram, R | 1 |
| Siegmund, B | 1 |
| Zeitz, M | 1 |
| Seksik, P | 3 |
| Mary, JY | 2 |
| Beaugerie, L | 1 |
| Lémann, M | 2 |
| Colombel, JF | 2 |
| Vernier-Massouille, G | 2 |
| Cosnes, J | 2 |
| Daniel, F | 1 |
| Cadranel, JF | 1 |
| Cazier, A | 1 |
| Duong Van Huyen, JP | 1 |
| Ziol, M | 1 |
| Coutarel, P | 1 |
| Loison, P | 1 |
| Jian, R | 1 |
| Marteau, P | 2 |
| Seiderer, J | 1 |
| Zech, CJ | 1 |
| Diebold, J | 1 |
| Schoenberg, SO | 1 |
| Brand, S | 1 |
| Tillack, C | 1 |
| Göke, B | 1 |
| Ochsenkühn, T | 1 |
| Reinisch, W | 1 |
| Laharie, D | 1 |
| Cadiot, G | 1 |
| Bouhnik, Y | 1 |
| De Vos, M | 1 |
| Boureille, A | 1 |
| Duclos, B | 1 |
| Ehmsen, L | 1 |
| Marko, C | 1 |
| Breidert, M | 1 |
1 review available for azathioprine and Focal Nodular Hyperplasia
| Article | Year |
|---|---|
Review article: the association between nodular regenerative hyperplasia, inflammatory bowel disease and thiopurine therapy.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Focal Nodular Hyperplasia; Humans; Immunos | 2013 |
7 other studies available for azathioprine and Focal Nodular Hyperplasia
| Article | Year |
|---|---|
Treatment with adalimumab in a patient with regenerative nodular hyperplasia secondary to azathioprine.
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Azathioprine; Focal Nodular | 2013 |
[Nodular regenerative hyperplasia as a side effect of azathioprine in a patient with Crohn's disease].
Topics: Ascites; Azathioprine; Blood Cell Count; Crohn Disease; Diagnosis, Differential; Fatigue; Focal Nodu | 2008 |
Incidence of nodular regenerative hyperplasia in inflammatory bowel disease patients treated with azathioprine.
Topics: Adult; Azathioprine; Female; Focal Nodular Hyperplasia; Humans; Immunosuppressive Agents; Incidence; | 2011 |
Azathioprine induced nodular regenerative hyperplasia in IBD patients.
Topics: Adult; Azathioprine; Focal Nodular Hyperplasia; Humans; Immunosuppressive Agents; Inflammatory Bowel | 2005 |
Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy.
Topics: Azathioprine; Crohn Disease; Focal Nodular Hyperplasia; Humans; Immunosuppressive Agents; Magnetic R | 2006 |
Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine.
Topics: Adolescent; Adult; Azathioprine; Child; Epidemiologic Methods; Europe; Female; Focal Nodular Hyperpl | 2007 |
[Portal vein hypertension during azathioprine therapy in patients with Crohn's disease--a frequent phenomenon?].
Topics: Azathioprine; Crohn Disease; Enbucrilate; Esophageal and Gastric Varices; Focal Nodular Hyperplasia; | 2008 |