Page last updated: 2024-10-23

azathioprine and Fatty Liver

azathioprine has been researched along with Fatty Liver in 9 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" Compared to controls, cases were higher in body mass index, anti-dsDNA antibody, prevalence of hypertension, antiphospholipid syndrome, and use of immunosuppressive medication, especially azathioprine and methotrexate; they were lower in IgM."3.78Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus. ( Aghdassi, E; Fortin, PR; Gladman, DD; Hirschfield, GM; Huang, D; Mosko, J; Su, J; Urowitz, MB, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Phillips, J1
Preskey, R1
Penfold, C1
Gordon, F1
Tyrrell-Price, J1
Schröder, T1
Schmidt, KJ1
Olsen, V1
Möller, S1
Mackenroth, T1
Sina, C1
Lehnert, H1
Fellermann, K1
Büning, J1
Huang, D1
Aghdassi, E1
Su, J1
Mosko, J1
Hirschfield, GM1
Gladman, DD1
Urowitz, MB1
Fortin, PR1
Moseley, RH1
Manoogian, B1
Shehab, T1
Saint, S1
Maier, KP1
Becker, K1
Knoblauch, M1
Lämmli, J1
Funk, C1
Mörl, M1
Börner, E1

Reviews

2 reviews available for azathioprine and Fatty Liver

ArticleYear
[Drug therapy in chronic liver disease].
    Praxis, 2005, Nov-30, Volume: 94, Issue:48

    Topics: Adenine; Administration, Oral; Anti-HIV Agents; Antiviral Agents; Azathioprine; Cholangitis, Scleros

2005
[Long-term prognosis in chronic liver diseases].
    Wiener medizinische Wochenschrift (1946), 1980, Sep-15, Volume: 130, Issue:17

    Topics: Alcoholism; Azathioprine; Cortisone; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosi

1980

Other Studies

7 other studies available for azathioprine and Fatty Liver

ArticleYear
Liver steatosis is a risk factor for hepatotoxicity in inflammatory bowel disease patients treated with azathioprine.
    European journal of gastroenterology & hepatology, 2020, Volume: 32, Issue:10

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Fatty Liver; Humans; Inflammatory Bowel Diseas

2020
Liver steatosis is a risk factor for hepatotoxicity in patients with inflammatory bowel disease under immunosuppressive treatment.
    European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Azathioprin

2015
Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus.
    The Journal of rheumatology, 2012, Volume: 39, Issue:2

    Topics: Adult; Alanine Transaminase; Antibodies, Neutralizing; Antiphospholipid Syndrome; Aspartate Aminotra

2012
Clinical problem-solving. An intricate interplay.
    The New England journal of medicine, 2012, Oct-04, Volume: 367, Issue:14

    Topics: alpha 1-Antitrypsin; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Diagnosis, Differential

2012
[Drug-induced liver diseases].
    Gastroenterologische Fortbildungskurse fur die Praxis, 1975, Volume: 5

    Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; C

1975
[Rehabilitation of patients with chronic liver diseases. Monitoring and therapy in the practive].
    Fortschritte der Medizin, 1974, Dec-05, Volume: 92, Issue:34

    Topics: Alcoholism; Azathioprine; Chronic Disease; Cortisone; Family Practice; Fatty Liver; Germany, West; H

1974
[Possibilities of the treatment of chronic liver diseases with and without vitamin B 12 -folic acid administration].
    Die Medizinische Welt, 1972, Aug-05, Volume: 23, Issue:31

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Azathioprine; Fatty Liver; Female; F

1972