Page last updated: 2024-10-23

azathioprine and Fatigue

azathioprine has been researched along with Fatigue in 10 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Pancytopenia was most likely azathioprine-related."3.74[Nodular regenerative hyperplasia as a side effect of azathioprine in a patient with Crohn's disease]. ( Günther, U; Loddenkemper, C; Preiss, JC; Schumann, M; Siegmund, B; Somasundaram, R; Zeitz, M, 2008)
"Treatment with azathioprine may - depending on its cumulative dosage - lead to pancytopenia and subsequent development of myelodysplasia or secondary leukaemia, respectively."3.72[Azathioprine-associated myelodysplastic syndrome with cytogenetic aberrations]. ( Kaiser, U; Schlegelberger, B; Wilkens, L; Willerding-Möllmann, S, 2004)
" Indications for switch, dosing and subsequent clinical outcomes (including thiopurine persistence) were recorded."1.48Low-dose thiopurine with allopurinol co-therapy overcomes thiopurine intolerance and allows thiopurine continuation in inflammatory bowel disease. ( Beswick, L; Friedman, AB; Haridy, J; Moltzen, A; Raghunath, A; Sparrow, M; van Langenberg, D; Vasudevan, A, 2018)
"Fatigue is a frequent symptom of patients with sarcoidosis."1.40Factors associated with fatigue in sarcoidosis. ( Bosse-Henck, A; Brähler, E; Fleischer, M; Hinz, A; Wirtz, H, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Bozzalla Cassione, E1
Zanframundo, G1
Biglia, A1
Codullo, V1
Montecucco, C1
Cavagna, L1
Vasudevan, A1
Beswick, L1
Friedman, AB1
Moltzen, A1
Haridy, J1
Raghunath, A1
Sparrow, M1
van Langenberg, D1
Fleischer, M1
Hinz, A1
Brähler, E1
Wirtz, H1
Bosse-Henck, A1
Schumann, M1
Preiss, JC1
Loddenkemper, C1
Günther, U1
Somasundaram, R1
Siegmund, B1
Zeitz, M1
Seinen, ML1
van Asseldonk, DP1
de Boer, NK1
Losekoot, N1
Smid, K1
Mulder, CJ1
Bouma, G1
Peters, GJ1
van Bodegraven, AA1
Tack, DK1
Paisansinsup, T1
Amin, S1
Willerding-Möllmann, S1
Wilkens, L1
Schlegelberger, B1
Kaiser, U1
Gause, A1
Inderrieden, DC1
Laas, R1
Arlt, AC1
Gross, WL1
Roenigk, HH1
Deodhar, S1
Kämpfen, P1
Hodler, J1

Other Studies

10 other studies available for azathioprine and Fatigue

ArticleYear
COVID-19 infection in a northern-Italian cohort of systemic lupus erythematosus assessed by telemedicine.
    Annals of the rheumatic diseases, 2020, Volume: 79, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Azathioprine; Betacoronavirus; Clinical Labora

2020
Low-dose thiopurine with allopurinol co-therapy overcomes thiopurine intolerance and allows thiopurine continuation in inflammatory bowel disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2018, Volume: 50, Issue:7

    Topics: Adolescent; Adult; Aged; Allopurinol; Australia; Azathioprine; Chemical and Drug Induced Liver Injur

2018
Factors associated with fatigue in sarcoidosis.
    Respiratory care, 2014, Volume: 59, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Fatigue; Female; Germany; Humans; Hyp

2014
[Nodular regenerative hyperplasia as a side effect of azathioprine in a patient with Crohn's disease].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:38

    Topics: Ascites; Azathioprine; Blood Cell Count; Crohn Disease; Diagnosis, Differential; Fatigue; Focal Nodu

2008
The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: results from a prospective pharmacological study.
    Journal of Crohn's & colitis, 2013, Volume: 7, Issue:10

    Topics: Adult; Allopurinol; Azathioprine; Drug Therapy, Combination; Enzyme Activation; Enzyme Inhibitors; F

2013
44-year-old woman with fatigue and dyspnea.
    Mayo Clinic proceedings, 2003, Volume: 78, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Dyspnea; Fatigue; Female; Humans; Immunosuppressive A

2003
[Azathioprine-associated myelodysplastic syndrome with cytogenetic aberrations].
    Deutsche medizinische Wochenschrift (1946), 2004, May-28, Volume: 129, Issue:22

    Topics: Anemia; Azathioprine; Bone Marrow; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Hum

2004
Common variable immunodeficiency (CVID) and inclusion body myositis (IBM).
    Immunobiology, 2000, Volume: 202, Issue:2

    Topics: Adult; Arthralgia; Azathioprine; Common Variable Immunodeficiency; Fatigue; gamma-Globulins; Humans;

2000
Pemphigus treatment with azathioprine. Clinical and immunologic correlation.
    Archives of dermatology, 1973, Volume: 107, Issue:3

    Topics: Adult; Aged; Antibodies; Azathioprine; Blood Platelets; Dose-Response Relationship, Drug; Fatigue; F

1973
[Treatment of chronic glomerulonephritis with imuran].
    Schweizerische medizinische Wochenschrift, 1970, Dec-05, Volume: 100, Issue:49

    Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Blood Sedimentation; Child; Chronic Disease; Colic; D

1970