Page last updated: 2024-10-23

azathioprine and Fabry Disease

azathioprine has been researched along with Fabry Disease in 3 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Fabry Disease: An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.

Research Excerpts

ExcerptRelevanceReference
"Granulomatosis with polyangiitis is characterized by the involvement of the respiratory tract and kidneys."1.40A rare association between Fabry's disease and granulomatosis with polyangiitis: a potential pathogenic link. ( Hanaoka, H; Hashiguchi, A; Ishii, T; Konishi, K; Kuwana, M, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hanaoka, H1
Hashiguchi, A1
Konishi, K1
Ishii, T1
Kuwana, M1
Van den Bergh, FA1
Rietra, PJ1
Kolk-Vegter, AJ1
Bosch, E1
Tager, JM1
Desnick, RJ1
Raman, M1
Allen, KY1
Desnick, SJ1
Simmons, RL1
Anderson, CF1
Woods, JE1
Najarian, JS1
Krivit, W1

Other Studies

3 other studies available for azathioprine and Fabry Disease

ArticleYear
A rare association between Fabry's disease and granulomatosis with polyangiitis: a potential pathogenic link.
    BMC nephrology, 2014, Oct-01, Volume: 15

    Topics: Adult; alpha-Galactosidase; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies,

2014
B.C.P. Jansen Institute, University of Amsterdam, Amsterdam, The Netherlands.
    Acta medica Scandinavica, 1976, Volume: 200, Issue:4

    Topics: Adult; Azathioprine; Ceramides; Cerebrosides; Fabry Disease; Follow-Up Studies; Galactosidases; Glyc

1976
Enzyme therapy in Fabry's disease by renal transplantation.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1972, Volume: 2

    Topics: Adult; Azathioprine; Ceramides; Fabry Disease; Female; Galactosidases; Galactosylgalactosylglucosylc

1972