azathioprine has been researched along with Eye Disorders in 31 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease." | 7.77 | Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011) |
| "To assess the efficacy of systemic corticosteroids alone as first-line treatment of polyarteritis nodosa (PAN) and microscopic polyangiitis (MPA) without poor-prognosis factors as defined by the Five-Factors Score (FFS), and to compare the efficacy and safety of azathioprine versus pulse cyclophosphamide as adjunctive immunosuppressive therapy for patients experiencing treatment failure or relapse." | 5.14 | Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: A prospective randomized study of one hundred twenty-four patients. ( Arène, JP; Carli, P; Cohen, P; Cordier, JF; Guillevin, L; Kyndt, X; Le Hello, C; Letellier, P; Mahr, A; Pagnoux, C; Puéchal, X; Ribi, C, 2010) |
| "To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease." | 3.77 | Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011) |
| "Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health." | 3.75 | Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983) |
| "Azathioprine was superior to placebo in the prevention of new eye disease in group 1 (1 vs." | 2.67 | A controlled trial of azathioprine in Behçet's syndrome. ( Barnes, CG; Lovatt, GE; Oğuz, V; Ozyazgan, Y; Pazarli, H; Serdaroğlu, S; Silman, A; Tüzün, Y; Yazici, H; Yurdakul, S, 1990) |
| "It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different." | 2.35 | Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975) |
| "Sarcoidosis is a multisystem disease of unknown aetiology with pulmonary involvement in most patients." | 1.48 | Atypical sarcoidosis-associated uveitis: diagnostic challenges. ( Cehajic Kapetanovic, J; Jones, NP; Steeples, LR, 2018) |
| "Untreated polyarteritis nodosa carries a very poor prognosis." | 1.29 | Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy. ( Akova, YA; Foster, CS; Jabbur, NS, 1993) |
| "Wegener's granulomatosis is a well-defined systemic vasculitic syndrome that primarily affects the upper and lower respiratory tracts and the kidney." | 1.29 | Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis. ( Gal, AA; LiVolsi, VA; Masor, JJ, 1994) |
| "Chronic relapsing polychondritis is a rare connective tissue disease of presumed autoimmunologic pathogenesis." | 1.28 | [Chronic recurrent polychondritis. The spectrum of eye involvement]. ( Althaus, C; Sundmacher, R, 1991) |
| "We found that untreated ocular cicatricial pemphigoid has a variable course and does not necessarily progress." | 1.27 | Immunosuppressive therapy in ocular cicatricial pemphigoid. ( Brown, SI; Mondino, BJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (58.06) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cehajic Kapetanovic, J | 1 |
| Jones, NP | 1 |
| Steeples, LR | 1 |
| Palestine, AG | 1 |
| Kolfenbach, JR | 1 |
| Ozzello, DJ | 1 |
| Bijlsma, WR | 1 |
| van den Bosch, WA | 1 |
| van Daele, PL | 1 |
| Paridaens, D | 1 |
| Cury, DB | 1 |
| Moss, AC | 1 |
| Ribi, C | 1 |
| Cohen, P | 1 |
| Pagnoux, C | 1 |
| Mahr, A | 1 |
| Arène, JP | 1 |
| Puéchal, X | 1 |
| Carli, P | 1 |
| Kyndt, X | 1 |
| Le Hello, C | 1 |
| Letellier, P | 1 |
| Cordier, JF | 1 |
| Guillevin, L | 1 |
| Kötter, I | 1 |
| Günaydin, I | 1 |
| Batra, M | 1 |
| Vonthein, R | 1 |
| Stübiger, N | 1 |
| Fierlbeck, G | 1 |
| Melms, A | 1 |
| Fauci, AS | 2 |
| Haynes, BF | 1 |
| Katz, P | 1 |
| Wolff, SM | 2 |
| Mondino, BJ | 1 |
| Brown, SI | 1 |
| Hornstein, OP | 1 |
| Djawari, D | 1 |
| Adhikary, HP | 1 |
| Sells, RA | 1 |
| Basu, PK | 1 |
| Foster, CS | 2 |
| Wilson, LA | 1 |
| Ekins, MB | 1 |
| Martenet, AC | 2 |
| Akova, YA | 1 |
| Jabbur, NS | 1 |
| Masor, JJ | 1 |
| Gal, AA | 1 |
| LiVolsi, VA | 1 |
| Messmer, EM | 1 |
| Hintschich, CR | 1 |
| Partscht, K | 1 |
| Messer, G | 1 |
| Kampik, A | 1 |
| Tackenberg, B | 1 |
| Hemmer, B | 1 |
| Oertel, WH | 1 |
| Sommer, N | 1 |
| Matuchansky, C | 1 |
| Ament, ME | 1 |
| James, DG | 1 |
| Firat, T | 1 |
| Gervasini, A | 1 |
| Althaus, C | 1 |
| Sundmacher, R | 1 |
| O'Duffy, JD | 1 |
| Yazici, H | 1 |
| Pazarli, H | 1 |
| Barnes, CG | 1 |
| Tüzün, Y | 1 |
| Ozyazgan, Y | 1 |
| Silman, A | 1 |
| Serdaroğlu, S | 1 |
| Oğuz, V | 1 |
| Yurdakul, S | 1 |
| Lovatt, GE | 1 |
| Jayson, MI | 1 |
| Jones, DE | 1 |
| Bonnet, M | 1 |
| Astle, JN | 1 |
| Ellis, PP | 1 |
| Horn, RG | 1 |
| Dale, DC | 1 |
| Klein, G | 1 |
| Fellner, S | 1 |
| Fellner, R | 1 |
| Brockhurst, RJ | 1 |
| Lam, KW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for azathioprine and Eye Disorders
| Article | Year |
|---|---|
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
[Non-infectious oral aphthous disorders. 2. Behçet's syndrome (malignant aphthosis)].
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Bone Diseases; Central Nervous System Diseas | 1980 |
Immunosuppressive treatment of ocular myasthenia gravis.
Topics: Adrenal Cortex Hormones; Azathioprine; Cholinesterase Inhibitors; Eye Diseases; Immunosuppressive Ag | 2001 |
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy; | 1975 |
Immunotherapy.
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; BCG Vaccine; Chlorambucil; Cyclophospha | 1977 |
[Immunodepressors in ophthalmology].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antibiotics, Antineoplastic; Antilymphocyte Se | 1971 |
5 trials available for azathioprine and Eye Disorders
| Article | Year |
|---|---|
Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: A prospective randomized study of one hundred twenty-four patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Fo | 2010 |
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
Behçet's syndrome.
Topics: Azathioprine; Behcet Syndrome; Clinical Trials as Topic; Eye Diseases; Humans; Suppuration; Uveitis | 1990 |
A controlled trial of azathioprine in Behçet's syndrome.
Topics: Adult; Azathioprine; Behcet Syndrome; Double-Blind Method; Eye Diseases; Humans; Male; Patient Compl | 1990 |
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies].
Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; E | 1972 |
21 other studies available for azathioprine and Eye Disorders
| Article | Year |
|---|---|
Atypical sarcoidosis-associated uveitis: diagnostic challenges.
Topics: Adrenal Cortex Hormones; Azathioprine; Choroiditis; Diagnosis, Differential; Drug Administration Sch | 2018 |
Rheumatologists and Ophthalmologists Differ in Treatment Decisions for Ocular Behçet Disease.
Topics: Administration, Topical; Azathioprine; Behcet Syndrome; Clinical Decision-Making; Eye Diseases; Gluc | 2016 |
Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease.
Topics: Adult; Aged; Azathioprine; Conjunctival Diseases; Drug Therapy, Combination; Eye Diseases; Eyelid Di | 2011 |
Ocular manifestations in a community-based cohort of patients with inflammatory bowel disease.
Topics: Acute Disease; Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; A | 2010 |
CNS involvement occurs more frequently in patients with Behçet's disease under cyclosporin A (CSA) than under other medications--results of a retrospective analysis of 117 cases.
Topics: Adolescent; Adult; Autonomic Nervous System Diseases; Azathioprine; Behcet Syndrome; Cohort Studies; | 2006 |
Immunosuppressive therapy in ocular cicatricial pemphigoid.
Topics: Aged; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Humans; Immunosuppressive Agents; Male; | 1983 |
Ocular complications of systemic steroid after renal transplantation and their association with HLA.
Topics: Adult; Azathioprine; Cataract; Eye Diseases; Female; HLA Antigens; Humans; Kidney Failure, Chronic; | 1982 |
Immunosuppressive therapy for progressive ocular cicatricial pemphigoid.
Topics: Adult; Aged; Azathioprine; Cicatrix; Conjunctival Diseases; Corneal Diseases; Cyclophosphamide; Drug | 1982 |
[Failures of cytostatic treatment in ophthalmology (author's transl)].
Topics: Adult; Azathioprine; Child; Corneal Diseases; Cyclophosphamide; Eye Diseases; Female; Humans; Immuno | 1980 |
Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy.
Topics: Adult; Aged; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Eye Diseases; Female; Humans | 1993 |
Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis.
Topics: Azathioprine; Eye Diseases; Female; Granulomatosis with Polyangiitis; Humans; Kidney; Middle Aged; P | 1994 |
[Ocular cicatricial pemphigoid. Retrospective analysis of risk factors and complications].
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathiopr | 2000 |
Inflammatory bowel diseases 1977.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Diet; Eye Diseases; Humans; Joint | 1977 |
Results of immunosuppressive treatment in Bechçet's disease: report of 55 cases.
Topics: Azathioprine; Behcet Syndrome; Cyclophosphamide; Drug Administration Schedule; Eye Diseases; Female; | 1978 |
[Case of Behcet's syndrome].
Topics: Adult; Anti-Bacterial Agents; Arthritis, Reactive; Azathioprine; Behcet Syndrome; Cicatrix; Diagnosi | 1977 |
[Chronic recurrent polychondritis. The spectrum of eye involvement].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Eye Diseases; Female; Fluocortolone; Fluorescein Ang | 1991 |
Scleritis and rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Age Factors; Arteritis; Arthritis, Rheumatoid; Azathioprine; Betamethas | 1971 |
Ocular complications in renal transplant patients.
Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov | 1974 |
Wegener's granulomatosis.
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Diagnosis, Differe | 1974 |
[Indications for immunosuppression by use of cytostatics in ophthalmology].
Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Azathioprine; Child; Corneal Transplantation; Cyclopho | 1972 |
Uveal effusion. II. Report of a case with analysis of subretinal fluid.
Topics: Acid Phosphatase; Adult; Animals; Azathioprine; Blood Proteins; Cattle; Cyclophosphamide; Electropho | 1973 |