azathioprine has been researched along with Eye Diseases in 31 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Eye Diseases: Diseases affecting the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease." | 7.77 | Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011) |
| "To assess the efficacy of systemic corticosteroids alone as first-line treatment of polyarteritis nodosa (PAN) and microscopic polyangiitis (MPA) without poor-prognosis factors as defined by the Five-Factors Score (FFS), and to compare the efficacy and safety of azathioprine versus pulse cyclophosphamide as adjunctive immunosuppressive therapy for patients experiencing treatment failure or relapse." | 5.14 | Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: A prospective randomized study of one hundred twenty-four patients. ( Arène, JP; Carli, P; Cohen, P; Cordier, JF; Guillevin, L; Kyndt, X; Le Hello, C; Letellier, P; Mahr, A; Pagnoux, C; Puéchal, X; Ribi, C, 2010) |
| "To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease." | 3.77 | Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011) |
| "Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health." | 3.75 | Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983) |
| "Azathioprine was superior to placebo in the prevention of new eye disease in group 1 (1 vs." | 2.67 | A controlled trial of azathioprine in Behçet's syndrome. ( Barnes, CG; Lovatt, GE; Oğuz, V; Ozyazgan, Y; Pazarli, H; Serdaroğlu, S; Silman, A; Tüzün, Y; Yazici, H; Yurdakul, S, 1990) |
| "It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different." | 2.35 | Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975) |
| "Sarcoidosis is a multisystem disease of unknown aetiology with pulmonary involvement in most patients." | 1.48 | Atypical sarcoidosis-associated uveitis: diagnostic challenges. ( Cehajic Kapetanovic, J; Jones, NP; Steeples, LR, 2018) |
| "Untreated polyarteritis nodosa carries a very poor prognosis." | 1.29 | Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy. ( Akova, YA; Foster, CS; Jabbur, NS, 1993) |
| "Wegener's granulomatosis is a well-defined systemic vasculitic syndrome that primarily affects the upper and lower respiratory tracts and the kidney." | 1.29 | Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis. ( Gal, AA; LiVolsi, VA; Masor, JJ, 1994) |
| "Chronic relapsing polychondritis is a rare connective tissue disease of presumed autoimmunologic pathogenesis." | 1.28 | [Chronic recurrent polychondritis. The spectrum of eye involvement]. ( Althaus, C; Sundmacher, R, 1991) |
| "We found that untreated ocular cicatricial pemphigoid has a variable course and does not necessarily progress." | 1.27 | Immunosuppressive therapy in ocular cicatricial pemphigoid. ( Brown, SI; Mondino, BJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (58.06) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cehajic Kapetanovic, J | 1 |
| Jones, NP | 1 |
| Steeples, LR | 1 |
| Palestine, AG | 1 |
| Kolfenbach, JR | 1 |
| Ozzello, DJ | 1 |
| Bijlsma, WR | 1 |
| van den Bosch, WA | 1 |
| van Daele, PL | 1 |
| Paridaens, D | 1 |
| Cury, DB | 1 |
| Moss, AC | 1 |
| Ribi, C | 1 |
| Cohen, P | 1 |
| Pagnoux, C | 1 |
| Mahr, A | 1 |
| Arène, JP | 1 |
| Puéchal, X | 1 |
| Carli, P | 1 |
| Kyndt, X | 1 |
| Le Hello, C | 1 |
| Letellier, P | 1 |
| Cordier, JF | 1 |
| Guillevin, L | 1 |
| Kötter, I | 1 |
| Günaydin, I | 1 |
| Batra, M | 1 |
| Vonthein, R | 1 |
| Stübiger, N | 1 |
| Fierlbeck, G | 1 |
| Melms, A | 1 |
| Fauci, AS | 2 |
| Haynes, BF | 1 |
| Katz, P | 1 |
| Wolff, SM | 2 |
| Mondino, BJ | 1 |
| Brown, SI | 1 |
| Hornstein, OP | 1 |
| Djawari, D | 1 |
| Adhikary, HP | 1 |
| Sells, RA | 1 |
| Basu, PK | 1 |
| Foster, CS | 2 |
| Wilson, LA | 1 |
| Ekins, MB | 1 |
| Martenet, AC | 2 |
| Akova, YA | 1 |
| Jabbur, NS | 1 |
| Masor, JJ | 1 |
| Gal, AA | 1 |
| LiVolsi, VA | 1 |
| Messmer, EM | 1 |
| Hintschich, CR | 1 |
| Partscht, K | 1 |
| Messer, G | 1 |
| Kampik, A | 1 |
| Tackenberg, B | 1 |
| Hemmer, B | 1 |
| Oertel, WH | 1 |
| Sommer, N | 1 |
| Matuchansky, C | 1 |
| Ament, ME | 1 |
| James, DG | 1 |
| Firat, T | 1 |
| Gervasini, A | 1 |
| Althaus, C | 1 |
| Sundmacher, R | 1 |
| O'Duffy, JD | 1 |
| Yazici, H | 1 |
| Pazarli, H | 1 |
| Barnes, CG | 1 |
| Tüzün, Y | 1 |
| Ozyazgan, Y | 1 |
| Silman, A | 1 |
| Serdaroğlu, S | 1 |
| Oğuz, V | 1 |
| Yurdakul, S | 1 |
| Lovatt, GE | 1 |
| Jayson, MI | 1 |
| Jones, DE | 1 |
| Bonnet, M | 1 |
| Astle, JN | 1 |
| Ellis, PP | 1 |
| Horn, RG | 1 |
| Dale, DC | 1 |
| Klein, G | 1 |
| Fellner, S | 1 |
| Fellner, R | 1 |
| Brockhurst, RJ | 1 |
| Lam, KW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for azathioprine and Eye Diseases
| Article | Year |
|---|---|
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
[Non-infectious oral aphthous disorders. 2. Behçet's syndrome (malignant aphthosis)].
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Bone Diseases; Central Nervous System Diseas | 1980 |
Immunosuppressive treatment of ocular myasthenia gravis.
Topics: Adrenal Cortex Hormones; Azathioprine; Cholinesterase Inhibitors; Eye Diseases; Immunosuppressive Ag | 2001 |
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy; | 1975 |
Immunotherapy.
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; BCG Vaccine; Chlorambucil; Cyclophospha | 1977 |
[Immunodepressors in ophthalmology].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antibiotics, Antineoplastic; Antilymphocyte Se | 1971 |
5 trials available for azathioprine and Eye Diseases
| Article | Year |
|---|---|
Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: A prospective randomized study of one hundred twenty-four patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Fo | 2010 |
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
Behçet's syndrome.
Topics: Azathioprine; Behcet Syndrome; Clinical Trials as Topic; Eye Diseases; Humans; Suppuration; Uveitis | 1990 |
A controlled trial of azathioprine in Behçet's syndrome.
Topics: Adult; Azathioprine; Behcet Syndrome; Double-Blind Method; Eye Diseases; Humans; Male; Patient Compl | 1990 |
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies].
Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; E | 1972 |
21 other studies available for azathioprine and Eye Diseases
| Article | Year |
|---|---|
Atypical sarcoidosis-associated uveitis: diagnostic challenges.
Topics: Adrenal Cortex Hormones; Azathioprine; Choroiditis; Diagnosis, Differential; Drug Administration Sch | 2018 |
Rheumatologists and Ophthalmologists Differ in Treatment Decisions for Ocular Behçet Disease.
Topics: Administration, Topical; Azathioprine; Behcet Syndrome; Clinical Decision-Making; Eye Diseases; Gluc | 2016 |
Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease.
Topics: Adult; Aged; Azathioprine; Conjunctival Diseases; Drug Therapy, Combination; Eye Diseases; Eyelid Di | 2011 |
Ocular manifestations in a community-based cohort of patients with inflammatory bowel disease.
Topics: Acute Disease; Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; A | 2010 |
CNS involvement occurs more frequently in patients with Behçet's disease under cyclosporin A (CSA) than under other medications--results of a retrospective analysis of 117 cases.
Topics: Adolescent; Adult; Autonomic Nervous System Diseases; Azathioprine; Behcet Syndrome; Cohort Studies; | 2006 |
Immunosuppressive therapy in ocular cicatricial pemphigoid.
Topics: Aged; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Humans; Immunosuppressive Agents; Male; | 1983 |
Ocular complications of systemic steroid after renal transplantation and their association with HLA.
Topics: Adult; Azathioprine; Cataract; Eye Diseases; Female; HLA Antigens; Humans; Kidney Failure, Chronic; | 1982 |
Immunosuppressive therapy for progressive ocular cicatricial pemphigoid.
Topics: Adult; Aged; Azathioprine; Cicatrix; Conjunctival Diseases; Corneal Diseases; Cyclophosphamide; Drug | 1982 |
[Failures of cytostatic treatment in ophthalmology (author's transl)].
Topics: Adult; Azathioprine; Child; Corneal Diseases; Cyclophosphamide; Eye Diseases; Female; Humans; Immuno | 1980 |
Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy.
Topics: Adult; Aged; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Eye Diseases; Female; Humans | 1993 |
Case report: Hashimoto's thyroiditis associated with Wegener's granulomatosis.
Topics: Azathioprine; Eye Diseases; Female; Granulomatosis with Polyangiitis; Humans; Kidney; Middle Aged; P | 1994 |
[Ocular cicatricial pemphigoid. Retrospective analysis of risk factors and complications].
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathiopr | 2000 |
Inflammatory bowel diseases 1977.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Diet; Eye Diseases; Humans; Joint | 1977 |
Results of immunosuppressive treatment in Bechçet's disease: report of 55 cases.
Topics: Azathioprine; Behcet Syndrome; Cyclophosphamide; Drug Administration Schedule; Eye Diseases; Female; | 1978 |
[Case of Behcet's syndrome].
Topics: Adult; Anti-Bacterial Agents; Arthritis, Reactive; Azathioprine; Behcet Syndrome; Cicatrix; Diagnosi | 1977 |
[Chronic recurrent polychondritis. The spectrum of eye involvement].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Eye Diseases; Female; Fluocortolone; Fluorescein Ang | 1991 |
Scleritis and rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Age Factors; Arteritis; Arthritis, Rheumatoid; Azathioprine; Betamethas | 1971 |
Ocular complications in renal transplant patients.
Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov | 1974 |
Wegener's granulomatosis.
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Diagnosis, Differe | 1974 |
[Indications for immunosuppression by use of cytostatics in ophthalmology].
Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Azathioprine; Child; Corneal Transplantation; Cyclopho | 1972 |
Uveal effusion. II. Report of a case with analysis of subretinal fluid.
Topics: Acid Phosphatase; Adult; Animals; Azathioprine; Blood Proteins; Cattle; Cyclophosphamide; Electropho | 1973 |