Page last updated: 2024-10-23

azathioprine and Experimental Leukemia

azathioprine has been researched along with Experimental Leukemia in 12 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furuta, K2
Ogiu, T2
Matsuoka, C2
Maekawa, A2
Medzihradsky, JL1
Hollowell, RP1
Elion, GB1
Harvey, JJ1
East, J1
Katz, FE1
Menahan, LA1
Kemp, RG1
Allison, AC1
Reid, RH1
Pirofsky, B1
Dawson, PJ1
Brambilla, G3
Parodi, S3
Cavanna, M3
Caraceni, CE2
Baldini, L2
Imamura, N1
Nakano, M1
Kawase, A1
Kawamura, Y1
Yokoro, K1
Cook, ES1
Nutini, LG1

Other Studies

12 other studies available for azathioprine and Experimental Leukemia

ArticleYear
[Effects of azathioprine-feeding or bone marrow transplantation on leukemogenic activity of N-butyl-N-nitrosourea (BNU) in Donryu rats (I). Sequential observations of immunological and histological changes in the subacute state].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1984, Issue:102

    Topics: Animals; Azathioprine; Bone Marrow Transplantation; Immunosuppressive Agents; Leukemia, Experimental

1984
[Effects of azathioprine-feeding or bone marrow transplantation on leukemogenic activity of N-butyl-N-nitrosourea (BNU) in Donryu rats (II). Effects on the induction of leukemia].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1984, Issue:102

    Topics: Animals; Azathioprine; Bone Marrow Transplantation; Immunosuppressive Agents; Leukemia, Experimental

1984
Differential inhibition by azathioprine and 6-mercaptopurine of specific suppressor T cell generation in mice.
    Journal of immunopharmacology, 1981, Volume: 3, Issue:1

    Topics: Animals; Azathioprine; Depression, Chemical; Leukemia, Experimental; Male; Mercaptopurine; Mice; She

1981
Azathioprine-induced lymphocytic neoplasms of NZB mice lack ecotropic murine leukaemia virus.
    International journal of cancer, 1979, Volume: 23, Issue:2

    Topics: Animals; Azathioprine; Cell Line; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma, Non-Hodg

1979
The effect of several lymphocytotoxic agents on murine leukemogenesis.
    Life sciences, 1978, Oct-23, Volume: 23, Issue:16

    Topics: Aging; Animals; Azathioprine; Body Weight; Cortisone; Dacarbazine; Leukemia, Experimental; Lymphocyt

1978
Tumour development following immunosuppression.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:10

    Topics: Adult; Animals; Antilymphocyte Serum; Azathioprine; Child; Cricetinae; Female; Humans; Immunity, Cel

1970
The influence of immunosuppression and allografting on virus-induced lymphatic leukemia in mice.
    Transplantation, 1972, Volume: 13, Issue:2

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Drug Synergism; Female; Immunosuppression Therapy; Leuk

1972
The immunodepressive activity of Escherichia coli L-asparaginase in some transplantation systems.
    Cancer research, 1970, Volume: 30, Issue:11

    Topics: Animals; Asparaginase; Azathioprine; Escherichia coli; Female; Graft vs Host Reaction; Immunosuppres

1970
Synergistic action of N-nitrosobutylurea and azathioprine in induction of leukemia in C57BL mice.
    Gan, 1973, Volume: 64, Issue:5

    Topics: AKR murine leukemia virus; Animals; Antigens, Viral; Azathioprine; Drug Synergism; Female; Immune Se

1973
The immunodepressive activity of N-diazoacetylglycine amide in some transplantation systems.
    Transplantation, 1970, Volume: 10, Issue:1

    Topics: Acetates; Amides; Animals; Azathioprine; Azo Compounds; Carcinoma, Ehrlich Tumor; Diazonium Compound

1970
Counteraction of leukopenia caused by mechlorethamine and azathioprine.
    Journal of surgical oncology, 1971, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Azathioprine; Dogs; Erythrocyte Count; Female; Kidney Transplantatio

1971
[Evaluation, in newborn Swiss mice, of the carcinogenic activity of some antineoplastic and immunosuppressive compounds].
    Bollettino della Societa italiana di biologia sperimentale, 1971, Jul-30, Volume: 47, Issue:14

    Topics: Adenoma; Animals; Animals, Newborn; Antineoplastic Agents; Asparaginase; Azathioprine; Fluorouracil;

1971