azathioprine has been researched along with Enlarged Liver in 9 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three cases of azathioprine-induced complex of liver diseases are described, and their light microscopy and ultrastructural findings are detailed." | 3.67 | Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations. ( Ackrill, P; Ali, HH; Haboubi, NY; Whitwell, HL, 1988) |
| "Treatment with prednisone, azathioprine, and ursodeoxycholic acid led to a good response." | 1.39 | Type 2 autoimmune hepatitis overlapping with primary sclerosing cholangitis in a 10-year-old boy. ( Bahri, I; Boudawara, T; Gargouri, L; Maalej, B; Mahfoudh, A; Majdoub, I; Mnif, H; Mnif, L; Safi, F; Tahri, N; Turki, F, 2013) |
| "Treatment with prednisone and azathioprine, plus, in three children, cyclosporine, resulted in complete remission in eight, partial remission in six, and failure in two." | 1.37 | Giant cell hepatitis with autoimmune hemolytic anemia in early childhood: long-term outcome in 16 children. ( Bernard, O; Choulot, JJ; Fabre, M; Gori, L; Jacquemin, E; Maggiore, G; Pacifico, L; Resti, M; Sciveres, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gargouri, L | 1 |
| Mnif, L | 1 |
| Safi, F | 1 |
| Turki, F | 1 |
| Majdoub, I | 1 |
| Maalej, B | 1 |
| Bahri, I | 1 |
| Mnif, H | 1 |
| Boudawara, T | 1 |
| Tahri, N | 1 |
| Mahfoudh, A | 1 |
| Maggiore, G | 1 |
| Sciveres, M | 1 |
| Fabre, M | 1 |
| Gori, L | 1 |
| Pacifico, L | 1 |
| Resti, M | 1 |
| Choulot, JJ | 1 |
| Jacquemin, E | 1 |
| Bernard, O | 1 |
| MATHE, G | 1 |
| AMIEL, JL | 1 |
| SCHWARZENBERG, L | 1 |
| CATTAN, A | 1 |
| SCHNEIDER, M | 1 |
| DEVRIES, MJ | 1 |
| TUBIANA, M | 1 |
| LALANNE, C | 1 |
| BINET, JL | 1 |
| PAPIERNIK, M | 1 |
| SEMAN, G | 1 |
| MATSUKURA, M | 1 |
| MERY, AM | 1 |
| SCHWARZMANN, V | 1 |
| FLAISLER, A | 1 |
| Knoblauch, M | 1 |
| Lämmli, J | 1 |
| Funk, C | 1 |
| Haboubi, NY | 1 |
| Ali, HH | 1 |
| Whitwell, HL | 1 |
| Ackrill, P | 1 |
| Baumann, W | 1 |
| Starzl, TE | 1 |
| Porter, KA | 1 |
| Brettschneider, L | 1 |
| Penn, I | 1 |
| Bell, P | 1 |
| Putnam, CW | 1 |
| McGuire, RL | 1 |
| Woolf, IL | 1 |
| B oyes, BE | 1 |
| Leeming, JT | 1 |
| Dymock, IW | 1 |
| Fossati, P | 1 |
| Racadot, A | 1 |
| Lefebvre, J | 1 |
| Decoulx, M | 1 |
| Linquette, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylactic Infusion of Donor Lymphocytes in Cord Blood Transplantation[NCT02328885] | Phase 1/Phase 2 | 17 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for azathioprine and Enlarged Liver
| Article | Year |
|---|---|
Type 2 autoimmune hepatitis overlapping with primary sclerosing cholangitis in a 10-year-old boy.
Topics: Alkaline Phosphatase; Azathioprine; Biomarkers; Child; Cholagogues and Choleretics; Cholangitis, Scl | 2013 |
Giant cell hepatitis with autoimmune hemolytic anemia in early childhood: long-term outcome in 16 children.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Bilirubin; Coom | 2011 |
SUCCESSFUL ALLOGENIC BONE MARROW TRANSPLANTATION IN MAN: CHIMERISM, INDUCED SPECIFIC TOLERANCE AND POSSIBLE ANTI-LEUKEMIC EFFECTS.
Topics: Antineoplastic Agents; Azathioprine; Bone Marrow Transplantation; Chimerism; Electrons; Genetic Dise | 1965 |
[Drug-induced liver diseases].
Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; C | 1975 |
Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations.
Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Endothelium; Female; Hepatomegaly; Huma | 1988 |
[Diagnosis, therapy and clinical course in chronic active hepatitis in childhood with special reference to immunological findings (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Azathioprine; Chemical and Drug Induced Liver Inju | 1974 |
Clinical and pathologic observations after orthotopic transplantation of the human liver.
Topics: Adolescent; Adult; Alkaline Phosphatase; Azathioprine; Bilirubin; Blood Proteins; Carcinoma, Hepatoc | 1969 |
Active chronic hepatitis in the elderly.
Topics: Age Factors; Aged; Azathioprine; Chronic Disease; Diabetes Mellitus; Female; Hepatitis; Hepatomegaly | 1974 |
[Action of azathioprine on a biological syndrome of alcoholic liver disease].
Topics: Adult; Alcoholism; Azathioprine; Female; Hepatomegaly; Humans; Polyneuropathies | 1968 |