Page last updated: 2024-10-23

azathioprine and End Stage Liver Disease

azathioprine has been researched along with End Stage Liver Disease in 4 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

End Stage Liver Disease: Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.

Research Excerpts

ExcerptRelevanceReference
" Secondary outcomes include safety and tolerability of MMF and azathioprine, time to remission, changes in Model For End-Stage Liver Disease (MELD)-score, adverse events, and aspects of quality of life."3.11Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial. ( Bakker, SF; Bartelink, M; Beuers, UHW; Biewenga, M; de Boer, YS; de Jonge, HJM; Drenth, JPH; Gevers, TJG; Gisbertz, IAM; Guichelaar, MMJ; Levens, AD; Pape, S; Pronk, MAMCB; Sebib Korkmaz, K; Sijtsma, MGM; Snijders, RJALM; Soufidi, K; Stoelinga, AEC; van den Berg, AP; van den Brand, FF; van der Meer, AJ; van Gerven, NMF; van Hoek, B; Vanwolleghem, T; Verdonk, RC; Verwer, BJ; Vrolijk, JM, 2022)
"An increased risk of colorectal cancer (CRC) is present also after LT in IBD patients with primary sclerosing cholangitis (PSC)."2.50Clinical management of inflammatory bowel disease in the organ recipient. ( Indriolo, A; Ravelli, P, 2014)
"Without prompt immunosuppressive treatment, autoimmune hepatitis is a devastating, albeit rare, liver disease."2.47Pharmacological management of autoimmune hepatitis. ( Mieli-Vergani, G; Vergani, D, 2011)
"16."1.46Autoimmune acute liver failure and seronegative autoimmune liver disease in children: Are they different from classical disease? ( Jain, V; Kathuria, R; Krishnani, N; Kumari, N; Poddar, U; Sarma, MS; Srivastava, A; Yachha, SK, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Snijders, RJALM2
Stoelinga, AEC2
Gevers, TJG2
Pape, S2
Biewenga, M2
Verdonk, RC2
de Jonge, HJM2
Vrolijk, JM2
Bakker, SF2
Vanwolleghem, T2
de Boer, YS2
Pronk, MAMCB2
Beuers, UHW2
van der Meer, AJ2
van Gerven, NMF2
Sijtsma, MGM2
Verwer, BJ2
Gisbertz, IAM2
Bartelink, M2
van den Brand, FF2
Sebib Korkmaz, K2
van den Berg, AP2
Guichelaar, MMJ2
Soufidi, K2
Levens, AD2
van Hoek, B2
Drenth, JPH2
Jain, V1
Srivastava, A1
Yachha, SK1
Kumari, N1
Kathuria, R1
Sarma, MS1
Poddar, U1
Krishnani, N1
Indriolo, A1
Ravelli, P1
Vergani, D1
Mieli-Vergani, G1

Reviews

2 reviews available for azathioprine and End Stage Liver Disease

ArticleYear
Clinical management of inflammatory bowel disease in the organ recipient.
    World journal of gastroenterology, 2014, Apr-07, Volume: 20, Issue:13

    Topics: Azathioprine; Cholangitis, Sclerosing; Colectomy; Colorectal Neoplasms; End Stage Liver Disease; Gra

2014
Pharmacological management of autoimmune hepatitis.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:4

    Topics: Adult; Azathioprine; Child; Disease Progression; End Stage Liver Disease; Hepatitis, Autoimmune; Hum

2011

Trials

1 trial available for azathioprine and End Stage Liver Disease

ArticleYear
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial.
    Trials, 2022, Dec-13, Volume: 23, Issue:1

    Topics: Adult; Azathioprine; End Stage Liver Disease; Hepatitis, Autoimmune; Humans; Immunosuppressive Agent

2022
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial.
    Trials, 2022, Dec-13, Volume: 23, Issue:1

    Topics: Adult; Azathioprine; End Stage Liver Disease; Hepatitis, Autoimmune; Humans; Immunosuppressive Agent

2022
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial.
    Trials, 2022, Dec-13, Volume: 23, Issue:1

    Topics: Adult; Azathioprine; End Stage Liver Disease; Hepatitis, Autoimmune; Humans; Immunosuppressive Agent

2022
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial.
    Trials, 2022, Dec-13, Volume: 23, Issue:1

    Topics: Adult; Azathioprine; End Stage Liver Disease; Hepatitis, Autoimmune; Humans; Immunosuppressive Agent

2022

Other Studies

1 other study available for azathioprine and End Stage Liver Disease

ArticleYear
Autoimmune acute liver failure and seronegative autoimmune liver disease in children: Are they different from classical disease?
    European journal of gastroenterology & hepatology, 2017, Volume: 29, Issue:12

    Topics: Adolescent; Alanine Transaminase; Ascites; Aspartate Aminotransferases; Autoantibodies; Autoimmune D

2017