Page last updated: 2024-10-23

azathioprine and Encephalitis

azathioprine has been researched along with Encephalitis in 18 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine is an immunosuppressive agent that reduces relapse rates in patients with multiple sclerosis (MS), but its efficacy in suppressing new brain lesions has never been evaluated."2.71Efficacy of azathioprine on multiple sclerosis new brain lesions evaluated using magnetic resonance imaging. ( Amaducci, L; Barilaro, A; Konze, A; Massacesi, L; Parigi, A; Pellicanò, G; Repice, AM; Siracusa, G; Taiuti, R, 2005)
"Hashimoto's encephalopathy (HE) is a rare neurological disorder."1.40Hashimoto's encephalopathy: South Korean experiences. ( Kang, K; Kim, BK; Kim, J; Kwon, O; Lee, JJ; Park, JM; Shin, H, 2014)
"HE is a rare disorder characterized by encephalopathy and central nervous system (CNS) dysfunction, elevated antithyroid antibodies, the absence of infection or structural abnormalities in the CNS, and a response to treatment with steroids."1.39Diagnostic and therapeutic aspects of Hashimoto's encephalopathy. ( Kirshner, H; Lagrange, AH; Moses, H; Olmez, I; Pawate, S; Sriram, S, 2013)
"Regarding recurrence, case 1 recurred 4 months after surgery and again 14 months after discontinuing prednisone; case 2 relapsed 16 months after receiving high-dose methylprednisolone pulse therapy; and case 3 recurred during the period of prednisone dose reduction."1.37Recurrent autoimmune hypophysitis successfully treated with glucocorticoids plus azathioprine: a report of three cases. ( Ba, JM; Dou, JT; Du, J; Gu, WJ; Guo, QH; Lu, JM; Lu, ZH; Mu, YM; Wang, XL; Yang, GQ, 2011)
"Drug treatment of late-stage human African Trypanosomiasis (HAT) in which the central nervous system (CNS) is involved may be complicated by a severe post-treatment reactive encephalopathy (PTRE) which can be fatal in up to 10% of cases."1.30The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of Human African Trypanosomiasis. ( Kennedy, PG, 1999)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's2 (11.11)29.6817
2010's7 (38.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Pellegrin, S1
Baldeweg, T1
Pujar, S1
D'Arco, F1
Cantalupo, G1
Varadkar, S1
Cross, JH1
Menzel, C1
Niederle, P1
Zorger, N1
Melamud, LI1
Fernández, VC1
Manin, A1
Villa, AM1
Olmez, I1
Moses, H1
Sriram, S1
Kirshner, H1
Lagrange, AH1
Pawate, S1
Kim, J1
Shin, H1
Kang, K1
Kwon, O1
Park, JM1
Kim, BK1
Lee, JJ1
Bolat, S1
Berding, G1
Dengler, R1
Stangel, M1
Trebst, C1
Mijajlovic, M1
Mirkovic, M1
Dackovic, J1
Zidverc-Trajkovic, J1
Sternic, N1
García Domínguez, JM1
Martínez Ginés, ML1
Martín-Barriga, ML1
Guzmán-de-Villoria, J1
Muñoz Blanco, JL1
de Andrés Frutos, C1
Yang, GQ1
Lu, ZH1
Gu, WJ1
Du, J1
Guo, QH1
Wang, XL1
Ba, JM1
Dou, JT1
Mu, YM1
Lu, JM1
Ferraria, N1
Rocha, S1
Fernandes, VS1
Correia, T1
Gonçalves, E1
Massacesi, L1
Parigi, A1
Barilaro, A1
Repice, AM1
Pellicanò, G1
Konze, A1
Siracusa, G1
Taiuti, R1
Amaducci, L1
Osetrov, BA1
Golovkin, VI1
Iunosova, LG1
De Lord, C1
Marsh, JC1
Smith, JG1
Singer, CR1
Gordon-Smith, EC1
Kennedy, PG1
Colenda, CC1
Gaston, JO1
Cendrowski, W1
Riekkinen, PJ1
Rinne, UK1
Manz, HJ1
Dinsdale, HB1
Morrin, PA1
Brendel, W1
Seifert, J1
Lob, G1

Reviews

1 review available for azathioprine and Encephalitis

ArticleYear
Immunosuppressive therapy in neurological diseases.
    Annals of clinical research, 1974, Volume: 6, Issue:6

    Topics: Adrenocorticotropic Hormone; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Cytara

1974

Trials

1 trial available for azathioprine and Encephalitis

ArticleYear
Efficacy of azathioprine on multiple sclerosis new brain lesions evaluated using magnetic resonance imaging.
    Archives of neurology, 2005, Volume: 62, Issue:12

    Topics: Adult; Azathioprine; Brain; Cross-Over Studies; Dose-Response Relationship, Drug; Encephalitis; Fema

2005

Other Studies

16 other studies available for azathioprine and Encephalitis

ArticleYear
Immunomodulation With Azathioprine Therapy in Rasmussen Syndrome: A Multimodal Evaluation.
    Neurology, 2021, 01-12, Volume: 96, Issue:2

    Topics: Adolescent; Azathioprine; Child; Cohort Studies; Encephalitis; Female; Follow-Up Studies; Humans; Im

2021
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018, Volume: 190, Issue:6

    Topics: Aged; Azathioprine; Capillary Permeability; Central Nervous System Diseases; Chronic Disease; Diagno

2018
Autoimmune encephalitis and immune therapy: lessons from Argentina.
    Acta neurologica Belgica, 2020, Volume: 120, Issue:3

    Topics: Adolescent; Adult; Aged; Argentina; Autoimmune Diseases; Azathioprine; Child; Cyclophosphamide; Ence

2020
Diagnostic and therapeutic aspects of Hashimoto's encephalopathy.
    Journal of the neurological sciences, 2013, Aug-15, Volume: 331, Issue:1-2

    Topics: Adult; Aged; Autoantibodies; Azathioprine; Brain Diseases; Child; Child, Preschool; Electroencephalo

2013
Hashimoto's encephalopathy: South Korean experiences.
    Acta neurologica Belgica, 2014, Volume: 114, Issue:3

    Topics: Aged; Aged, 80 and over; Antimetabolites; Azathioprine; Brain; Brain Diseases; Electroencephalograph

2014
Fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in the diagnosis of neurosarcoidosis.
    Journal of the neurological sciences, 2009, Dec-15, Volume: 287, Issue:1-2

    Topics: Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Encephalitis; Fluorodeoxyglucose F1

2009
Clinical manifestations, diagnostic criteria and therapy of Hashimoto's encephalopathy: report of two cases.
    Journal of the neurological sciences, 2010, Jan-15, Volume: 288, Issue:1-2

    Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Electroencephalography; Encep

2010
[Recurrent acute rhombencephalomyelitis in an adult or neuromyelitis optica? Presentation of a case].
    Neurologia (Barcelona, Spain), 2012, Volume: 27, Issue:3

    Topics: Azathioprine; Brain Stem; Corticosterone; Encephalitis; Female; Humans; Immunoglobulins, Intravenous

2012
Recurrent autoimmune hypophysitis successfully treated with glucocorticoids plus azathioprine: a report of three cases.
    Endocrine journal, 2011, Volume: 58, Issue:8

    Topics: Adult; Aged; Anti-Inflammatory Agents; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination;

2011
Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation.
    BMJ case reports, 2013, Jan-25, Volume: 2013

    Topics: Anti-Inflammatory Agents; Antibodies, Antinuclear; Ataxia; Azathioprine; Child; Cognition Disorders;

2013
[Long-term remission of leukoencephalitis during treatment with imuran].
    Klinicheskaia meditsina, 1984, Volume: 62, Issue:7

    Topics: Adult; Azathioprine; Encephalitis; Female; Humans

1984
Fatal autoimmune pancytopenia following bone marrow transplantation for aplastic anaemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Aspergillosis; Autoantibodies; Autoimmune Di

1996
The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of Human African Trypanosomiasis.
    Journal of neuroimmunology, 1999, Volume: 100, Issue:1-2

    Topics: Analgesics; Animals; Azathioprine; Disease Models, Animal; Eflornithine; Encephalitis; Hippocampus;

1999
Psychogenic unresponsiveness in a patient with lupus cerebritis.
    Southern medical journal, 1986, Volume: 79, Issue:2

    Topics: Adult; Azathioprine; Coma; Drug Therapy, Combination; Encephalitis; Humans; Lupus Erythematosus, Sys

1986
Progressive multifocal leukoencephalopathy after renal transplantation. Demonstration of Papova-like virions.
    Annals of internal medicine, 1971, Volume: 75, Issue:1

    Topics: Adult; Autopsy; Azathioprine; Brain; Demyelinating Diseases; Encephalitis; Female; Gliosis; Humans;

1971
Effect of 'maximum immune suppression' with thoracic duct drainage, ALG, azathioprine and cortisone in some neurological disorders.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:6

    Topics: Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Central Nervous System Diseases; Cortisone;

1972