Page last updated: 2024-10-23

azathioprine and Emesis

azathioprine has been researched along with Emesis in 23 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"A controlled trial in 20 adult patients with the nephrotic syndrome due to proliferative glomerulonephritis compared the effects of consecutive eight-week courses of treatment with prednisolone in conventional dosage and a low-dose azathioprine-prednisolone combination."9.03Nephrotic syndrome due to primary renal disease in adults: II. A controlled trial of prednisolone and azathioprine. ( Cameron, JS; Ogg, CS; Sharpstone, P, 1969)
"To determine whether the presence of thiopurine methyltransferase (TPMT) alleles associated with reduced or absent activity of thiopurine methyltransferase is a major factor for withdrawal of azathioprine (AZA) in rheumatoid arthritis (RA) patients."7.72Is thiopurine methyltransferase genetic polymorphism a major factor for withdrawal of azathioprine in rheumatoid arthritis patients? ( Baiget, M; Corominas, H; de Cuevillas, F; Díaz, C; Domènech, M; Geli, C; Gich, I; Laíz, A; Moreno, M; Vázquez, G, 2003)
"A retrospective review of the literature has been carried out to determine laboratory abnormalities occurring in patients with rheumatoid arthritis (RA) treated with azathioprine, in order to establish a profile for this agent in the treatment of this disease."7.66Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities. ( Pelkey, J; Whisnant, JK, 1982)
"Azathioprine (AZA) is an immunosuppressive drug that is widely used in the treatment of autoimmune diseases."5.51Severe cholestasis due to azathioprine in Behcet's disease. ( Gisi, K; Ispiroglu, M; Kantarceken, B; Sayar, H, 2019)
"Azathioprine was administrated to all of them for periods varying from two and a half to six months."5.25The effect of azathioprine on gastric mucosal histology and acid secretion in chronic gastritis. ( Jorge, AD; Sanchez, D, 1973)
"A controlled trial in 20 adult patients with the nephrotic syndrome due to proliferative glomerulonephritis compared the effects of consecutive eight-week courses of treatment with prednisolone in conventional dosage and a low-dose azathioprine-prednisolone combination."5.03Nephrotic syndrome due to primary renal disease in adults: II. A controlled trial of prednisolone and azathioprine. ( Cameron, JS; Ogg, CS; Sharpstone, P, 1969)
" Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug."3.73Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005)
"To determine whether the presence of thiopurine methyltransferase (TPMT) alleles associated with reduced or absent activity of thiopurine methyltransferase is a major factor for withdrawal of azathioprine (AZA) in rheumatoid arthritis (RA) patients."3.72Is thiopurine methyltransferase genetic polymorphism a major factor for withdrawal of azathioprine in rheumatoid arthritis patients? ( Baiget, M; Corominas, H; de Cuevillas, F; Díaz, C; Domènech, M; Geli, C; Gich, I; Laíz, A; Moreno, M; Vázquez, G, 2003)
"We describe two patients with rheumatic disease who developed nausea, vomiting, fever and diarrhea after a single dose of azathioprine."3.67Adverse reactions to azathioprine mimicking gastroenteritis. ( Assini, JF; Hamilton, R; Strosberg, JM, 1986)
"A retrospective review of the literature has been carried out to determine laboratory abnormalities occurring in patients with rheumatoid arthritis (RA) treated with azathioprine, in order to establish a profile for this agent in the treatment of this disease."3.66Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities. ( Pelkey, J; Whisnant, JK, 1982)
"Rates of malignancy were within published ranges for transplant recipients."2.68Mycophenolate mofetil for maintenance therapy in kidney transplantation. ( Gonwa, TA, 1996)
"The use of MMF is associated with slight increases in gastrointestinal adverse effects, some hematologic adverse events, and CMV infections compared with Aza."2.42Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review. ( Li, H; Li, Y; Lu, Y; Wang, K; Wei, Q; Yang, Y; Zhang, H, 2004)
"Demyelination is similar with malignancy in clinical symptoms."1.72Astrocytoma with myelin oligodendrocyte glycoprotein antibody associated encephalomyelitis: A case report. ( Gu, H; Liu, X; Yang, S; Zhang, J; Zhong, G, 2022)
"Among those cases, isolated gastric Crohn's disease is even rarer."1.51Pyloric stenosis as a manifestation of isolated gastric Crohn's disease responding to intralesional steroid injection and balloon dilation: a case report. ( Balendran, K; Nawaraththne, NMM; Udumalagala, S, 2019)
"Azathioprine (AZA) is an immunosuppressive drug that is widely used in the treatment of autoimmune diseases."1.51Severe cholestasis due to azathioprine in Behcet's disease. ( Gisi, K; Ispiroglu, M; Kantarceken, B; Sayar, H, 2019)
" Systemic treatment usually begins with high dosage corticosteroids."1.42Atypical Cogan's syndrome: a case report and summary of current treatment options. ( Jančatová, D; Komínek, P; Matoušek, P; Zeleník, K, 2015)
"Azathioprine was administrated to all of them for periods varying from two and a half to six months."1.25The effect of azathioprine on gastric mucosal histology and acid secretion in chronic gastritis. ( Jorge, AD; Sanchez, D, 1973)
"Azathioprine (Imuran) was administered to seven patients with ulcerative colitis suffering from a relapse which could not be controlled by adrenocortical steroids."1.25Treatment of ulcerative colitis with azathioprine. ( Gilon, E; Theodor, E; Waks, U, 1968)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199011 (47.83)18.7374
1990's1 (4.35)18.2507
2000's3 (13.04)29.6817
2010's7 (30.43)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Zhong, G1
Zhang, J1
Liu, X1
Yang, S1
Gu, H1
Balendran, K1
Udumalagala, S1
Nawaraththne, NMM1
Zhang, Y1
Kou, G1
Li, Y3
Gisi, K1
Ispiroglu, M1
Kantarceken, B1
Sayar, H1
Frapard, T1
Amoura, Z1
Pineton de Chambrun, M1
Yachoui, R1
Kolasinski, SL1
Han, BK1
Jančatová, D1
Zeleník, K1
Komínek, P1
Matoušek, P1
Ferraria, N1
Rocha, S1
Fernandes, VS1
Correia, T1
Gonçalves, E1
Corominas, H1
Domènech, M1
Laíz, A1
Gich, I1
Geli, C1
Díaz, C1
de Cuevillas, F1
Moreno, M1
Vázquez, G1
Baiget, M1
Wang, K1
Zhang, H1
Wei, Q1
Li, H1
Yang, Y1
Lu, Y1
Bajaj, JS1
Saeian, K1
Varma, RR1
Franco, J1
Knox, JF1
Podoll, J1
Emmons, J1
Levy, M1
Binion, DG1
Whisnant, JK1
Pelkey, J1
Gonwa, TA1
Assini, JF1
Hamilton, R1
Strosberg, JM1
Salaman, JR1
Mahmood, K1
Jorge, AD1
Sanchez, D1
Pounder, RE1
Sharpstone, P1
Ogg, CS1
Cameron, JS1
Thumb, N1
Gangl, A1
Horak, W1
Richter, H1
Kleine, FD1
Keitel, W1
Franke, A1
Kämpfen, P1
Hodler, J1
Schäfer, KH1
Bläker, F1
Theodor, E1
Gilon, E1
Waks, U1

Reviews

1 review available for azathioprine and Emesis

ArticleYear
Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review.
    Transplantation proceedings, 2004, Volume: 36, Issue:7

    Topics: Azathioprine; Cytomegalovirus Infections; Follow-Up Studies; Humans; Immunosuppressive Agents; Incid

2004

Trials

2 trials available for azathioprine and Emesis

ArticleYear
Mycophenolate mofetil for maintenance therapy in kidney transplantation.
    Clinical transplantation, 1996, Volume: 10, Issue:1 Pt 2

    Topics: Antilymphocyte Serum; Azathioprine; Cytomegalovirus Infections; Diarrhea; Double-Blind Method; Graft

1996
Nephrotic syndrome due to primary renal disease in adults: II. A controlled trial of prednisolone and azathioprine.
    British medical journal, 1969, May-31, Volume: 2, Issue:5656

    Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Creatinine; Drug Synergism; Female;

1969

Other Studies

20 other studies available for azathioprine and Emesis

ArticleYear
Astrocytoma with myelin oligodendrocyte glycoprotein antibody associated encephalomyelitis: A case report.
    Medicine, 2022, Oct-07, Volume: 101, Issue:40

    Topics: Aquaporin 4; Astrocytoma; Autoantibodies; Azathioprine; Demyelinating Diseases; Dizziness; Encephalo

2022
Pyloric stenosis as a manifestation of isolated gastric Crohn's disease responding to intralesional steroid injection and balloon dilation: a case report.
    Journal of medical case reports, 2019, Nov-13, Volume: 13, Issue:1

    Topics: Abdominal Pain; Adult; Azathioprine; Crohn Disease; Dilatation; Endoscopy, Digestive System; Female;

2019
A woman with intractable nausea and vomiting.
    BMJ (Clinical research ed.), 2018, Apr-19, Volume: 361

    Topics: Adult; Alkalosis; Antiemetics; Azathioprine; Delayed Diagnosis; Female; Functional Neuroimaging; Hum

2018
Severe cholestasis due to azathioprine in Behcet's disease.
    BMJ case reports, 2019, Mar-31, Volume: 12, Issue:3

    Topics: Adult; Azathioprine; Behcet Syndrome; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; I

2019
Intractable Nausea and Vomiting: Gut Is Not Always the Answer.
    The American journal of medicine, 2019, Volume: 132, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Magnetic Res

2019
Intractable vomiting as an initial presentation of lupus-related neuromyelitis optica.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2013, Volume: 19, Issue:3

    Topics: Adult; Azathioprine; Cyclophosphamide; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lu

2013
Atypical Cogan's syndrome: a case report and summary of current treatment options.
    International journal of pediatric otorhinolaryngology, 2015, Volume: 79, Issue:3

    Topics: Adolescent; Azathioprine; Cogan Syndrome; Female; Glucocorticoids; Hearing Loss, Bilateral; Hearing

2015
Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation.
    BMJ case reports, 2013, Jan-25, Volume: 2013

    Topics: Anti-Inflammatory Agents; Antibodies, Antinuclear; Ataxia; Azathioprine; Child; Cognition Disorders;

2013
Is thiopurine methyltransferase genetic polymorphism a major factor for withdrawal of azathioprine in rheumatoid arthritis patients?
    Rheumatology (Oxford, England), 2003, Volume: 42, Issue:1

    Topics: 5' Untranslated Regions; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Case-Control Stu

2003
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:5

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus

2005
Rheumatoid arthritis: treatment with azathioprine (IMURAN (R)). Clinical side-effects and laboratory abnormalities.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Adult; Aged; Anorexia; Arthritis, Rheumatoid; Azathioprine; Bacterial Infections; Chemical and Drug

1982
Adverse reactions to azathioprine mimicking gastroenteritis.
    The Journal of rheumatology, 1986, Volume: 13, Issue:6

    Topics: Azathioprine; Diarrhea; Female; Fever; Gastrointestinal Diseases; Humans; Middle Aged; Nausea; Vomit

1986
Recurrent mesenteric venous thrombosis complicating renal transplantation.
    British journal of urology, 1974, Volume: 46, Issue:3

    Topics: Anuria; Azathioprine; Creatinine; Female; Gangrene; Humans; Intestine, Small; Kidney Transplantation

1974
The effect of azathioprine on gastric mucosal histology and acid secretion in chronic gastritis.
    Gut, 1973, Volume: 14, Issue:2

    Topics: Adult; Aged; Azathioprine; Biopsy; Female; Gastric Juice; Gastric Mucosa; Gastritis; Humans; Male; M

1973
Pancreatic exocrine deficiency, chronic active hepatitis and familial autoallergic haemolytic anaemia.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:5

    Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Chronic Disease; Diarrhea; Female; Hepatitis; Humans; M

1974
[Experiences with the immunosuppressive treatment of rheumatoid arthritis].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1969, Volume: 1

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Benzoates;

1969
[Therapy with immunosuppressive agents in hepatology].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jun-15, Volume: 24, Issue:12

    Topics: Azathioprine; Colitis; Headache; Hepatitis; Humans; Leukocytes; Liver Cirrhosis; Liver Diseases; Pai

1969
[Treatment of chronic glomerulonephritis with imuran].
    Schweizerische medizinische Wochenschrift, 1970, Dec-05, Volume: 100, Issue:49

    Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Blood Sedimentation; Child; Chronic Disease; Colic; D

1970
Experiences with immunosuppressive therapy in childhood ulcerative colitis.
    Zeitschrift fur Kinderheilkunde, 1971, Volume: 110, Issue:4

    Topics: Adolescent; Azathioprine; Child; Cholestasis; Colitis, Ulcerative; Enema; Female; Humans; Immunosupp

1971
Treatment of ulcerative colitis with azathioprine.
    British medical journal, 1968, Dec-21, Volume: 4, Issue:5633

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Colitis, Ulcerative; Female; Humans; Leuko

1968