azathioprine has been researched along with Elevated Cholesterol in 21 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the relative influences of cyclosporine (CsA) therapy, corticosteroid therapy, and other clinical variables on posttransplant hypercholesterolemia, total serum cholesterol levels were measured in 107 renal transplant recipients receiving one of three immunosuppression regimens: CsA and azathioprine (AZA) (group I); CsA, AZA, and prednisone (group II); or AZA and prednisone (group III)." | 7.68 | Independent effects of cyclosporine and prednisone on posttransplant hypercholesterolemia. ( Hricik, DE; Mayes, JT; Schulak, JA, 1991) |
| "With lovastatin there was a 27% increase in the WBC (from 6220 +/- 530 cells/mm3 to 7780 +/- 510 cells/mm3, P less than 0." | 6.67 | Lovastatin treatment of hypercholesterolemia in renal transplant recipients. ( Goryance, JM; Heim-Duthoy, KL; Kasiske, BL; Rao, KV; Tortorice, KL, 1990) |
| "From 14 cyclosporine (CsA)-treated and 11 azathioprine (AZA)-treated patients with hypercholesterolemia, more than 1 year after kidney transplantation, we determined NK cell number and cytotoxic activity before, and at 6 and 12 weeks after, initiating pravastatin treatment." | 3.71 | Reassuring effect of pravastatin on natural killer cell activity in stable renal transplant patients. ( Ijzermans, JN; Vaessen, LM; van Gelder, T; van Miert, PP; Weimar, W, 2001) |
| "To clarify the relative influences of cyclosporine (CsA) therapy, corticosteroid therapy, and other clinical variables on posttransplant hypercholesterolemia, total serum cholesterol levels were measured in 107 renal transplant recipients receiving one of three immunosuppression regimens: CsA and azathioprine (AZA) (group I); CsA, AZA, and prednisone (group II); or AZA and prednisone (group III)." | 3.68 | Independent effects of cyclosporine and prednisone on posttransplant hypercholesterolemia. ( Hricik, DE; Mayes, JT; Schulak, JA, 1991) |
| " Dosing of these agents was concentration-controlled and open-labeled." | 2.71 | Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study. ( Bäckman, L; Brattström, C; Calne, R; Campistol, JM; Charpentier, B; Claesson, K; Durand, D; Groth, CG; Kreis, H; Lang, P; Morales, JM; Touraine, JL; Wramner, L, 2003) |
| "The Lovastatin treatment did not results in more adverse events than the placebo treatment." | 2.68 | [The effect of hypolipidemia treatment on the function of kidney transplanted from cadavers]. ( Bill, M; Durlik, M; Gaciong, Z; Gradowska, L; Juskowa, J; Lao, M; Paczek, L; Wyzgał, J, 1997) |
| "With lovastatin there was a 27% increase in the WBC (from 6220 +/- 530 cells/mm3 to 7780 +/- 510 cells/mm3, P less than 0." | 2.67 | Lovastatin treatment of hypercholesterolemia in renal transplant recipients. ( Goryance, JM; Heim-Duthoy, KL; Kasiske, BL; Rao, KV; Tortorice, KL, 1990) |
| "Atherogenic hypercholesteremia was found as frequently in patients on CyA as in those on Aza/P." | 2.66 | [Cyclosporin A and hyperlipidemia after kidney transplantation. Prospective study]. ( Brunner, FP; Hodel, K; Mordasini, RC; Thiel, G, 1986) |
| "These data suggest that long-term renal function in cyclosporine-treated kidney transplant patients is primarily influenced by the occurrence of early and late rejection episodes rather than by the dosage or duration of cyclosporine therapy." | 1.29 | Long-term renal function in cyclosporine-treated renal allograft recipients. ( Hodge, E; Novick, AC; Streem, S; Tanabe, K, 1995) |
| "The prevalence of hyperlipidemia in adolescents and young adults who are long-term survivors of pediatric renal transplantation with stable graft function has not previously been examined." | 1.29 | Hyperlipidemia in long-term survivors of pediatric renal transplantation. ( Hunninghake, DB; Kashtan, CE; Matas, AJ; Myers, TA; Sharma, AK, 1994) |
| " The most significant factor responsible for these metabolic complications was the total dosage of prednisone and cyclosporine." | 1.29 | Metabolic problems in recipients of liver transplants. ( Filo, RS; Hughes, D; Jindal, RM; Leapman, SB; Lumeng, L; Milgrom, ML; Pescovitz, MD; Sidner, RA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Charpentier, B | 1 |
| Groth, CG | 1 |
| Bäckman, L | 1 |
| Morales, JM | 1 |
| Calne, R | 1 |
| Kreis, H | 1 |
| Lang, P | 1 |
| Touraine, JL | 1 |
| Claesson, K | 1 |
| Campistol, JM | 1 |
| Durand, D | 1 |
| Wramner, L | 1 |
| Brattström, C | 1 |
| Pannu, HS | 1 |
| Singh, D | 1 |
| Sandhu, JS | 1 |
| Punch, JD | 1 |
| Shieck, VL | 1 |
| Campbell, DA | 1 |
| Bromberg, JS | 1 |
| Turcotte, JG | 1 |
| Merion, RM | 1 |
| Tanabe, K | 2 |
| Novick, AC | 1 |
| Streem, S | 1 |
| Hodge, E | 1 |
| Islam, MS | 1 |
| Bard, JM | 1 |
| Le Pogamp, P | 1 |
| Leglise, D | 1 |
| Bourbigot, B | 1 |
| Rivalan, J | 1 |
| Cledes, J | 1 |
| Sharma, AK | 1 |
| Myers, TA | 1 |
| Hunninghake, DB | 1 |
| Matas, AJ | 1 |
| Kashtan, CE | 1 |
| Jindal, RM | 1 |
| Sidner, RA | 1 |
| Hughes, D | 1 |
| Pescovitz, MD | 1 |
| Leapman, SB | 1 |
| Milgrom, ML | 1 |
| Lumeng, L | 1 |
| Filo, RS | 1 |
| Paczek, L | 1 |
| Bill, M | 1 |
| Wyzgał, J | 1 |
| Gaciong, Z | 1 |
| Gradowska, L | 2 |
| Juskowa, J | 1 |
| Durlik, M | 1 |
| Lao, M | 1 |
| Melchor, JL | 1 |
| Gracida, C | 1 |
| Manu, M | 1 |
| Tokumoto, T | 1 |
| Ishikawa, N | 1 |
| Shimizu, T | 1 |
| Okuda, H | 1 |
| Ito, S | 1 |
| Shimmura, H | 1 |
| Inui, M | 1 |
| Harano, M | 1 |
| Shiroyanagi, Y | 1 |
| Yagisawa, T | 1 |
| Fuchinoue, S | 1 |
| Toma, H | 1 |
| Vaessen, LM | 1 |
| van Miert, PP | 1 |
| van Gelder, T | 1 |
| Ijzermans, JN | 1 |
| Weimar, W | 1 |
| Brunner, G | 1 |
| Hricik, DE | 1 |
| Mayes, JT | 1 |
| Schulak, JA | 1 |
| Ettenger, RB | 1 |
| Rosenthal, JT | 1 |
| Marik, J | 1 |
| Grimm, PC | 1 |
| Nelson, P | 1 |
| Malekzadeh, MH | 1 |
| Fine, RN | 1 |
| Isoniemi, H | 1 |
| Tikkanen, M | 1 |
| Häyry, P | 1 |
| Eklund, B | 1 |
| Höckerstedt, K | 1 |
| Salmela, K | 1 |
| Ahonen, J | 1 |
| Gossard, D | 1 |
| Langlais, J | 1 |
| Kasiske, BL | 1 |
| Tortorice, KL | 1 |
| Heim-Duthoy, KL | 1 |
| Goryance, JM | 1 |
| Rao, KV | 1 |
| Hess, ML | 1 |
| Hastillo, A | 1 |
| Thompson, JA | 1 |
| Sansonetti, DJ | 1 |
| Szentpetery, S | 1 |
| Barnhart, G | 1 |
| Lower, RR | 1 |
| Hodel, K | 1 |
| Mordasini, RC | 1 |
| Brunner, FP | 1 |
| Thiel, G | 1 |
| Orlowski, T | 1 |
| Kardasiewicz, W | 1 |
| Rowińska, D | 1 |
| Scheitlin, W | 1 |
| Brunner, F | 1 |
7 trials available for azathioprine and Elevated Cholesterol
| Article | Year |
|---|---|
Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study.
Topics: Adrenal Cortex Hormones; Azathioprine; Cyclosporine; Drug Therapy, Combination; France; Graft Reject | 2003 |
Corticosteroid withdrawal after liver transplantation.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Azathioprine; Cyclosporine; Diabetes Mellitus, | 1995 |
[The effect of hypolipidemia treatment on the function of kidney transplanted from cadavers].
Topics: Adult; Anticholesteremic Agents; Azathioprine; Cadaver; Cholesterol; Cholesterol, LDL; Creatinine; C | 1997 |
Treatment of hypercholesterolemia with fluvastatin in kidney transplant patients.
Topics: Adult; Anticholesteremic Agents; Azathioprine; Cholesterol; Cholesterol, LDL; Cyclosporine; Drug The | 1998 |
Lipid profiles with triple drug immunosuppressive therapy and with double drug combinations after renal transplantation and stable graft function.
Topics: Azathioprine; Cyclosporins; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hyperlipidemias | 1991 |
Lovastatin treatment of hypercholesterolemia in renal transplant recipients.
Topics: Adolescent; Apolipoprotein A-I; Apolipoproteins A; Azathioprine; Child; Child, Preschool; Cholestero | 1990 |
[Cyclosporin A and hyperlipidemia after kidney transplantation. Prospective study].
Topics: Adult; Azathioprine; Cyclosporins; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Immunosupp | 1986 |
14 other studies available for azathioprine and Elevated Cholesterol
| Article | Year |
|---|---|
Lipid profile before and after renal transplantation--a longitudinal study.
Topics: Adult; Azathioprine; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cyclosporine | 2003 |
Long-term renal function in cyclosporine-treated renal allograft recipients.
Topics: Adult; Azathioprine; Chi-Square Distribution; Creatinine; Cyclosporine; Female; Graft Rejection; Hum | 1995 |
Serum lipoprotein (a) in renal transplant recipients treated with cyclosporin monotherapy compared to conventional treatment.
Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemias; Kidn | 1994 |
Hyperlipidemia in long-term survivors of pediatric renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Cohort Stud | 1994 |
Metabolic problems in recipients of liver transplants.
Topics: Adult; Azathioprine; Carbohydrate Metabolism; Creatinine; Cyclosporine; Diabetes Mellitus; Female; F | 1996 |
Impact of tacrolimus on hyperlipidemia after renal transplantation: a Japanese single center experience.
Topics: Adult; Azathioprine; Cholesterol; Cholesterol, HDL; Cyclosporine; Drug Therapy, Combination; Female; | 2000 |
Reassuring effect of pravastatin on natural killer cell activity in stable renal transplant patients.
Topics: Anticholesteremic Agents; Azathioprine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporin | 2001 |
[Therapy of the chronic destructive, non-purulent cholangitis (primary biliary cirrhosis)].
Topics: Azathioprine; Calcium; Cholangitis; Cholestyramine Resin; Clofibrate; Humans; Hypercholesterolemia; | 1976 |
Independent effects of cyclosporine and prednisone on posttransplant hypercholesterolemia.
Topics: Adult; Azathioprine; Cholesterol; Cyclosporins; Drug Therapy, Combination; Female; Humans; Hyperchol | 1991 |
Long-term results with cyclosporine immune suppression in pediatric cadaver renal transplantation.
Topics: Adolescent; Age Factors; Azathioprine; Cadaver; Child; Cyclosporins; Growth; Humans; Hypercholestero | 1991 |
Transplantation and lipids.
Topics: Arteriosclerosis; Azathioprine; Cyclosporins; Humans; Hypercholesterolemia; Lipid Metabolism; Postop | 1991 |
Lipid mediators in organ transplantation: does cyclosporine accelerate coronary atherosclerosis?
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Child; Coronary Disease; Cyclosporins; Female | 1987 |
Rejection of renal allografts in man.
Topics: Adrenal Cortex Hormones; Azathioprine; Blood Cell Count; Creatinine; Dactinomycin; Erythropoietin; G | 1971 |
[Follow-up studies of Zurich clinical cases].
Topics: Adult; Azathioprine; Cadaver; Chronic Disease; Follow-Up Studies; Glomerulonephritis; Hematologic Di | 1967 |