Page last updated: 2024-10-23

azathioprine and Eczema

azathioprine has been researched along with Eczema in 20 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Eczema: A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed).

Research Excerpts

ExcerptRelevanceReference
"This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of alitretinoin for the treatment of adults with severe chronic hand eczema refractory to topical steroid treatment in accordance with the licensed indication, based upon the evidence submission from Basilea Pharmaceuticals Ltd to the National Institute for Health and Clinical Excellence (NICE) as part of the single technology appraisal process."8.86Alitretinoin for the treatment of severe chronic hand eczema. ( Duffy, S; Griffin, S; Ingram, JR; Paulden, M; Rodgers, M; Sculpher, M; Slack, R; Woolacott, N, 2010)
"Azathioprine is frequently used in severe eczema."7.88Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine. ( Bruijnzeel-Koomen, CAF; de Bruin-Weller, MS; de Graaf, M; Garritsen, FM; van den Broek, MPH; van der Schaft, J; van Schaik, RH, 2018)
"Nine patients with eczema were treated with the immunosuppressive drugs cyclophosphamide and azathioprine."7.66Treatment of eczema with cyclophosphamide and azathioprine. ( Morrison, JG; Schulz, EJ, 1978)
"This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of alitretinoin for the treatment of adults with severe chronic hand eczema refractory to topical steroid treatment in accordance with the licensed indication, based upon the evidence submission from Basilea Pharmaceuticals Ltd to the National Institute for Health and Clinical Excellence (NICE) as part of the single technology appraisal process."4.86Alitretinoin for the treatment of severe chronic hand eczema. ( Duffy, S; Griffin, S; Ingram, JR; Paulden, M; Rodgers, M; Sculpher, M; Slack, R; Woolacott, N, 2010)
"Azathioprine is frequently used in severe eczema."3.88Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine. ( Bruijnzeel-Koomen, CAF; de Bruin-Weller, MS; de Graaf, M; Garritsen, FM; van den Broek, MPH; van der Schaft, J; van Schaik, RH, 2018)
"Nine patients with eczema were treated with the immunosuppressive drugs cyclophosphamide and azathioprine."3.66Treatment of eczema with cyclophosphamide and azathioprine. ( Morrison, JG; Schulz, EJ, 1978)
"Azathioprine has been available for 30 years and is used in a variety of dermatologic conditions."2.38Azathioprine in dermatology. ( Colver, GB; Harris, DW; Younger, IR, 1991)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's4 (20.00)18.2507
2000's1 (5.00)29.6817
2010's7 (35.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Voorberg, AN1
Kamphuis, E1
Christoffers, WA1
Romeijn, GLE1
Oosterhaven, JAF1
Schuttelaar, MLA1
Wollenberg, A1
Kinberger, M1
Arents, B1
Aszodi, N1
Avila Valle, G1
Barbarot, S1
Bieber, T1
Brough, HA1
Calzavara Pinton, P1
Christen-Zäch, S1
Deleuran, M1
Dittmann, M1
Dressler, C1
Fink-Wagner, AH1
Fosse, N1
Gáspár, K1
Gerbens, L1
Gieler, U1
Girolomoni, G1
Gregoriou, S1
Mortz, CG1
Nast, A1
Nygaard, U1
Redding, M1
Rehbinder, EM1
Ring, J1
Rossi, M1
Serra-Baldrich, E1
Simon, D1
Szalai, ZZ1
Szepietowski, JC1
Torrelo, A1
Werfel, T1
Flohr, C1
McWhirter, S1
Robinson, P1
Orchard, D1
Oosterhaven, JA1
Politiek, K1
Schuttelaar, MA1
Garritsen, FM2
van der Schaft, J2
Bruijnzeel-Koomen, CAF2
van Schaik, RH1
de Graaf, M2
van den Broek, MPH2
de Bruin-Weller, MS2
Hijnen, DJ1
Hon, KL1
Chang, M1
Chong, SC1
Yuen, YP1
Tsui, SKW1
Bagherani, N1
Smoller, BR1
Riis, JL1
Vestergaard, C1
Hjuler, KF1
Iversen, L1
Jakobsen, L1
Deleuran, MS1
Olsen, M1
Paulden, M1
Rodgers, M1
Griffin, S1
Slack, R1
Duffy, S1
Ingram, JR1
Woolacott, N1
Sculpher, M1
White, JM1
Salisbury, JR1
Creamer, D1
Ahmed, AR1
Moy, R1
Lear, JT1
English, JS1
Jones, P1
Smith, AG1
Lyons, F1
Scerri, L1
Morrison, JG1
Schulz, EJ1
Szarmach, H1
Poniecka, H1
Niczyporuk, W1
Younger, IR1
Harris, DW1
Colver, GB1
Gunnar, S1
Johansson, O1
Juhlin, L1
Lapière, CM1
Salmon, J1

Reviews

3 reviews available for azathioprine and Eczema

ArticleYear
Alitretinoin for the treatment of severe chronic hand eczema.
    Health technology assessment (Winchester, England), 2010, Volume: 14 Suppl 1

    Topics: Algorithms; Alitretinoin; Azathioprine; Chronic Disease; Cyclosporine; Dermatologic Agents; Eczema;

2010
Azathioprine.
    International journal of dermatology, 1981, Volume: 20, Issue:7

    Topics: Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Colitis, Ulcerative; Crohn Diseas

1981
Azathioprine in dermatology.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:2 Pt 1

    Topics: Azathioprine; Drug Interactions; Eczema; Humans; Leukopenia; Pemphigoid, Bullous; Pemphigus; Skin Di

1991

Trials

1 trial available for azathioprine and Eczema

ArticleYear
Efficacy and safety of oral alitretinoin versus oral azathioprine in patients with severe chronic hand eczema: Results from a prematurely discontinued randomized controlled trial.
    Contact dermatitis, 2022, Volume: 87, Issue:4

    Topics: Administration, Oral; Alitretinoin; Azathioprine; Chronic Disease; Dermatitis, Allergic Contact; Der

2022

Other Studies

16 other studies available for azathioprine and Eczema

ArticleYear
European guideline (EuroGuiDerm) on atopic eczema: part I - systemic therapy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:9

    Topics: Adolescent; Azathioprine; Child; Cyclosporine; Dermatitis, Atopic; Eczema; Humans; Immunosuppressive

2022
Asthma improvement in children with eczema treated with azathioprine: A case series.
    The Australasian journal of dermatology, 2021, Volume: 62, Issue:2

    Topics: Adolescent; Asthma; Azathioprine; Child; Comorbidity; Eczema; Female; Humans; Immunosuppressive Agen

2021
Azathioprine treatment and drug survival in patients with chronic hand eczema - results from daily practice.
    Contact dermatitis, 2017, Volume: 76, Issue:5

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Azathioprine; Chronic

2017
Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:4

    Topics: Adult; Azathioprine; Chromatography, High Pressure Liquid; Dermatitis, Atopic; Eczema; Female; Guani

2018
Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema.
    Acta dermato-venereologica, 2018, Mar-13, Volume: 98, Issue:3

    Topics: Adult; Allopurinol; Azathioprine; Chronic Disease; Dermatitis, Atopic; Drug Therapy, Combination; Ec

2018
Adverse Effects of Azathioprine in a Child and Her Mother with Eczema.
    Indian journal of pediatrics, 2018, Volume: 85, Issue:10

    Topics: Adolescent; Alopecia; Azathioprine; Eczema; Female; Humans; Immunosuppressive Agents; Middle Aged; N

2018
Effectiveness of azathioprine pulse therapy in prolonging remission of psoriasis.
    Dermatologic therapy, 2017, Volume: 30, Issue:1

    Topics: Azathioprine; Dermatitis, Atopic; Eczema; Humans; Psoriasis

2017
Hospital-diagnosed atopic dermatitis and long-term risk of myocardial infarction: a population-based follow-up study.
    BMJ open, 2016, 11-11, Volume: 6, Issue:11

    Topics: Adult; Aged; Ambulatory Care; Azathioprine; Case-Control Studies; Cyclosporine; Denmark; Dermatitis,

2016
Eczematous changes on the hands--quiz case. Diagnosis: "Mechanic's hands" as part of the antisynthetase syndrome.
    Archives of dermatology, 2005, Volume: 141, Issue:6

    Topics: Azathioprine; Biopsy, Needle; Drug Therapy, Combination; Eczema; Female; Follow-Up Studies; Hand Der

2005
Retrospective review of the use of azathioprine in severe atopic dermatitis.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:4

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Dermatitis, Atopic;

1996
Treatment of common skin complaints--changing referral patterns.
    Irish medical journal, 1997, Volume: 90, Issue:7

    Topics: Acne Vulgaris; Anthralin; Azathioprine; Dermatitis, Atopic; Dermatology; Diagnosis, Differential; Ec

1997
Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses.
    Advances in experimental medicine and biology, 1999, Volume: 455

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Eczema; Eczema, Dyshidrotic; Female; Human

1999
Treatment of eczema with cyclophosphamide and azathioprine.
    The British journal of dermatology, 1978, Volume: 98, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Ecz

1978
[Effect of imuran on experimental eczema].
    Przeglad dermatologiczny, 1976, Issue:6 Suppl

    Topics: Animals; Azathioprine; Dinitrochlorobenzene; Eczema; Female; Guinea Pigs; Immunization; Male; Skin

1976
Immunoglobulin E in "healed" atopic dermatitis and after treatment with corticosteroids and azathioprine.
    The British journal of dermatology, 1970, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Eczema; Female; gamma-Globulins; Humans;

1970
[An unusual indication for treatment with immunosuppressive agents: erythrodermic eczema].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:3

    Topics: Azathioprine; Dermatitis, Exfoliative; Eczema; Glucocorticoids; Humans; Male; Mercaptopurine; Middle

1970