Page last updated: 2024-10-23

azathioprine and Eczema, Atopic

azathioprine has been researched along with Eczema, Atopic in 77 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine is frequently used in severe eczema."7.88Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine. ( Bruijnzeel-Koomen, CAF; de Bruin-Weller, MS; de Graaf, M; Garritsen, FM; van den Broek, MPH; van der Schaft, J; van Schaik, RH, 2018)
"Azathioprine is frequently used in severe eczema."3.88Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine. ( Bruijnzeel-Koomen, CAF; de Bruin-Weller, MS; de Graaf, M; Garritsen, FM; van den Broek, MPH; van der Schaft, J; van Schaik, RH, 2018)
"We present a case of drug-induced alveolitis following infliximab and azathioprine for the treatment of severe, generalised psoriasis and atopic eczema without pre-existing lung disease."3.74[Drug-induced alveolitis associated with infliximab/azathioprine therapy]. ( Dercken, HG; El-Hag, K; Hölzle, E; Prenzel, R, 2008)
" He had CD4 lymphocytopenia during azathioprine and topical corticosteroid therapy for atopic dermatitits (AD)."3.69Kaposi's sarcoma during immunosuppressive therapy for atopic dermatitis. ( Janssens, P; Lachapelle, JM; Lambert, M; Tennstedt, D; Vandercam, B, 1997)
"Azathioprine has an important role in treatment of many inflammatory dermatoses."3.69Azathioprine in dermatology: a survey of current practice in the U.K. ( English, JS; Gawkrodger, DJ; Lear, JT; Tan, BB, 1997)
"Azathioprine is an accessible drug for patients in many countries, including underdeveloped countries, and therefore it is used by many dermatologists in moderate and severe AD."2.82The use of azathioprine in atopic dermatitis: A review. ( Bracho-Borro, M; Franco-Ruiz, PA; Magaña, M, 2022)
"Patients with severe atopic eczema frequently require systemic treatment to control their disease."2.76A randomized trial of methotrexate versus azathioprine for severe atopic eczema. ( Bos, JD; Leeflang, MM; Roekevisch, E; Schmitt, J; Schram, ME; Spuls, PI, 2011)
" TPMT-based dosing seemed to reduce predicted toxicity, and drug efficacy was maintained."2.72Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial. ( Gray, JC; Meggitt, SJ; Reynolds, NJ, 2006)
"Leukopenia was observed in two patients and deranged liver enzymes in eight during treatment with azathioprine."2.70Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial. ( Agarwal, S; Ahmed, I; Barclay, G; Berth-Jones, J; Graham-Brown, RA; Hotchkiss, K; Takwale, A; Tan, E, 2002)
"Atopic dermatitis is a common, chronic pruritic condition affecting both children and adults, which has a negative impact on the quality of life."2.53Guidelines for the Management of Atopic Dermatitis in Singapore. ( Chan, YC; Chandran, NS; Ho, MS; Koh, MJ; Lim, YL; Tang, MB; Tay, YK; Thirumoorthy, T, 2016)
" Safety data were compared by calculating the weekly incidence rates (as percentages) for adverse events."2.50Efficacy and safety of systemic treatments for moderate-to-severe atopic dermatitis: a systematic review. ( Kuester, D; Limpens, J; Roekevisch, E; Schmitt, J; Spuls, PI, 2014)
"The optimal treatment of atopic dermatitis requires regular medical supervision."2.42[Systemic therapy of atopic dermatitis]. ( Breuer, K; Heratizadeh, A; Kapp, A; Werfel, T, 2003)
" The mean initial dosage of AZA was 1."1.51A Retrospective Study of Systemic Treatment of Severe Atopic Dermatitis With Azathioprine: Effectiveness and Tolerance in 11 Pediatric Patients. ( Hernández-Martín, A; Knöpfel, N; Noguera-Morel, L; Torrelo, A, 2019)
"Oral azathioprine was associated with few pronounced adverse effects for the duration of use and dosage in this cohort."1.42The adverse effect profile of oral azathioprine in pediatric atopic dermatitis, and recommendations for monitoring. ( Bragoli, W; Fuggle, NR; Glover, M; Kinsler, VA; Mahto, A; Martinez, AE, 2015)
"Atopic dermatitis is the most common chronic inflammatory skin disease with high prevalence rates in adults and even higher among children."1.42The anti-IL-4 receptor alpha antibody dupilumab: facing a new era in treating atopic dermatitis. ( Luger, TA; Tsianakas, A, 2015)
"In this third of 4 sections, treatment of atopic dermatitis with phototherapy and systemic immunomodulators, antimicrobials, and antihistamines is reviewed, including indications for use and the risk-benefit profile of each treatment option."1.40Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. ( Begolka, WS; Berger, TG; Bergman, JN; Block, J; Chamlin, SL; Cohen, DE; Cooper, KD; Cordoro, KM; Davis, DM; Eichenfield, LF; Elmets, CA; Feldman, SR; Hanifin, JM; Harrod, CG; Krol, A; Margolis, DJ; Paller, AS; Schwarzenberger, K; Sidbury, R; Silverman, RA; Simpson, EL; Tom, WL; Williams, HC, 2014)
"Azathioprine therapy was associated with clinical improvement in all but 1 patient."1.39Oral azathioprine for recalcitrant pediatric atopic dermatitis: clinical response and thiopurine monitoring. ( Caufield, M; Tom, WL, 2013)
"Our experience shows that, when adjusted to thiopurine methyltransferase activity, azathioprine is a safe drug for the treatment of children with severe atopic dermatitis."1.36[Safety of azathioprine therapy adjusted to thiopurine methyltransferase activity in the treatment of infantile atopic dermatitis. Report on 7 cases]. ( Borrego, L; Islas, D; Martel, RM; Melwani, P; Peñate, Y, 2010)
"Azathioprine was stopped in one female after 4 months due to lack of efficacy."1.35Efficacy and tolerability at 3 and 6 months following use of azathioprine for recalcitrant atopic dermatitis in children and young adults. ( Ching, GK; Chow, CM; Hon, KL; Lee, KK; Leung, TF; Ng, PC, 2009)
"A 61-year-old Chinese man with severe atopic eczema developed moderate myelosuppression with standard doses of azathioprine."1.35TPMT*26 (208F-->L), a novel mutation detected in a Chinese. ( Aw, DC; Kham, SK; Soh, CK; Yeoh, AE, 2009)
"We suggest that food hypersensitivity should be ruled out in patients with hypereosinophilia, hyper-IgE syndrome, and atopic dermatitis."1.35Hypereosinophilia, hyper-IgE syndrome, and atopic dermatitis in a toddler with food hypersensitivity. ( Estrada-Reyes, E; Gamboa-Marrufo, JD; Hernnández-Román, MP; Nava-Ocampo, AA; Valencia-Herrera, A, 2008)
"Effective treatment of severe adult atopic eczema may necessitate the use of agents such as systemic steroids, PUVA or cyclosporin, which are associated with significant morbidity."1.30The use of azathioprine in severe adult atopic eczema. ( Baldwin, P; Buckley, DA; Rogers, S, 1998)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.19)18.7374
1990's6 (7.79)18.2507
2000's17 (22.08)29.6817
2010's43 (55.84)24.3611
2020's7 (9.09)2.80

Authors

AuthorsStudies
Bracho-Borro, M1
Franco-Ruiz, PA1
Magaña, M1
de Graaf, M3
Janmohamed, SR1
Schuttelaar, MLA1
Agner, T2
Alfonso, JH1
De Schepper, S1
Deleuran, M2
Despontin, K1
Elenius, V1
Ghislain, PD1
Huilaja, L1
Johansson, EK1
Kvenshagen, BK1
Mandelin, JM1
Olset, H1
Svensson, A2
van Tuyll van Serooskerken, AM1
Thyssen, JP1
Vestergaard, C2
Wollenberg, A1
Kinberger, M1
Arents, B1
Aszodi, N1
Avila Valle, G1
Barbarot, S1
Bieber, T3
Brough, HA1
Calzavara Pinton, P1
Christen-Zäch, S1
Dittmann, M1
Dressler, C1
Fink-Wagner, AH1
Fosse, N1
Gáspár, K1
Gerbens, L1
Gieler, U1
Girolomoni, G1
Gregoriou, S1
Mortz, CG1
Nast, A1
Nygaard, U1
Redding, M1
Rehbinder, EM1
Ring, J1
Rossi, M1
Serra-Baldrich, E1
Simon, D2
Szalai, ZZ1
Szepietowski, JC1
Torrelo, A2
Werfel, T3
Flohr, C5
Cheirif-Wolosky, O1
Elizalde-Jiménez, IG1
Romero, MTG1
Singh, P1
Silverberg, JI1
Drucker, AM1
Ellis, AG1
Bohdanowicz, M1
Mashayekhi, S1
Yiu, ZZN1
Rochwerg, B1
Di Giorgio, S1
Arents, BWM1
Burton, T1
Spuls, PI7
Küster, D1
Siegels, D1
Schmitt, J5
Pino Lopez, J1
Kromer, C1
Herr, R1
Schmieder, A1
Bayerl, C1
Schaarschmidt, ML1
Prezzano, JC1
Beck, LA3
Davis, DM2
Borok, J1
Udkoff, J1
Lio, P1
Spergel, J1
Garritsen, FM4
van der Schaft, J5
Bruijnzeel-Koomen, CAF2
van Schaik, RH2
van den Broek, MPH3
de Bruin-Weller, MS6
Roekevisch, E6
Schram, ME3
Leeflang, MMG3
Brouwer, MWD2
Gerbens, LAA2
Bos, JD3
Hijnen, DJ1
Hamann, SAS1
Lacour, JP1
van den Heuvel, JM1
Bruijnzeel-Koomen, CAFM1
Maitland-van der Zee, AH1
Ordóñez Rubiano, MF1
Arenas, CM1
Chalela, JG1
von Kobyletzki, LB1
Weidinger, S2
Kabashima, K1
Irvine, AD2
Noguera-Morel, L1
Knöpfel, N1
Hernández-Martín, A1
Vicente Villa, A1
Solman, L1
Lloyd-Lavery, A1
Grindlay, DJC1
Rogers, NK1
Thomas, KS1
Harman, KE1
Alexander, H1
Patton, T1
Jabbar-Lopez, ZK1
Manca, A1
Kuester, D1
Limpens, J1
Sidbury, R2
Cohen, DE1
Cordoro, KM1
Berger, TG1
Bergman, JN1
Chamlin, SL1
Cooper, KD1
Feldman, SR1
Hanifin, JM1
Krol, A1
Margolis, DJ1
Paller, AS2
Schwarzenberger, K1
Silverman, RA1
Simpson, EL1
Tom, WL2
Williams, HC1
Elmets, CA1
Block, J1
Harrod, CG1
Begolka, WS1
Eichenfield, LF2
Thomsen, SF1
Karlsmark, T1
Clemmensen, KK1
Graversgaard, C1
Ibler, KS1
Jemec, GB1
Fuggle, NR1
Bragoli, W1
Mahto, A1
Glover, M1
Martinez, AE1
Kinsler, VA1
Deinum, J1
van den Broek, MP1
Bruijnzeel-Koomen, CA2
Tsianakas, A1
Luger, TA1
Notaro, ER1
Politiek, K1
van den Reek, JM1
Kievit, W1
de Jong, EM1
Schuttelaar, ML1
Védie, AL1
Ezzedine, K1
Amazan, E1
Boralevi, F1
Milpied, B1
Taïeb, A1
Seneschal, J1
Bagherani, N1
Smoller, BR1
Tan, SH1
Yew, YW1
Tay, YK1
Chan, YC1
Chandran, NS1
Ho, MS1
Koh, MJ1
Lim, YL1
Tang, MB1
Thirumoorthy, T1
Riis, JL1
Hjuler, KF1
Iversen, L1
Jakobsen, L1
Deleuran, MS1
Olsen, M1
Totri, CR1
Logan, K1
Proudfoot, L1
Lara-Corrales, I1
Sugarman, J1
Tom, W1
Siegfried, E1
Cordoro, K1
Abraham, S1
Trautmann, F1
Stephan, V1
Fölster-Holst, R1
Homey, B1
Novak, N1
Sticherling, M1
Augustin, M1
Kleinheinz, A1
Elsner, P1
Campbell, LE1
Irwin McLean, WH1
Kezic, S1
Middelkamp-Hup, MA1
Chong, JH1
Koh, MJA1
Hughes, R1
Collins, P1
Rogers, S2
Hon, KL1
Ching, GK1
Leung, TF1
Chow, CM1
Lee, KK1
Ng, PC1
Wolverton, SE1
Kham, SK1
Soh, CK1
Aw, DC1
Yeoh, AE1
Shaw, MG1
Burkhart, CN1
Morrell, DS1
Martel, RM1
Melwani, P1
Islas, D1
Peñate, Y1
Borrego, L1
Lai, SW1
Wang, YC1
Wang, CH1
Huang, TY1
Wee, JS1
Marinaki, A1
Smith, CH1
Thiryayi, WA1
Leeflang, MM1
Denby, KS1
Caufield, M1
Tan, AU1
Gonzalez, ME1
Murphy, LA1
Atherton, D1
Berth-Jones, J1
Takwale, A1
Tan, E1
Barclay, G1
Agarwal, S1
Ahmed, I1
Hotchkiss, K1
Graham-Brown, RA1
Heratizadeh, A1
Breuer, K1
Kapp, A1
Malthieu, F1
Guillet, G1
Larregue, M1
Bodemer, C1
Bernier, C1
Meggitt, SJ2
Gray, JC1
Reynolds, NJ2
Favrot, C1
Reichmuth, P1
Olivry, T1
El-Hag, K1
Dercken, HG1
Prenzel, R1
Hölzle, E1
Estrada-Reyes, E1
Hernnández-Román, MP1
Gamboa-Marrufo, JD1
Valencia-Herrera, A1
Nava-Ocampo, AA1
Lear, JT2
English, JS2
Jones, P1
Smith, AG1
Vandercam, B1
Lachapelle, JM1
Janssens, P1
Tennstedt, D1
Lambert, M1
Tan, BB1
Gawkrodger, DJ1
Buckley, DA1
Baldwin, P1
Lyons, F1
Kuanprasert, N1
Herbert, O1
Barnetson, RS1
Numata, T1
Mizuno, N1
Russell Jones, R1
Anderson, C1
Gunnar, S1
Johansson, O1
Juhlin, L1
Thomas, F1
Owens, L1
Thomas, J1
Wolf, JS1
Volk, M1
Mendez, G1
Lee, HM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Baricitinib Versus Azathioprine in Combination With Topical Corticosteroids For Patients With Moderate-to-Severe Atopic Dermatitis[NCT05969730]40 participants (Anticipated)Interventional2023-08-15Recruiting
Effects of Abrocitinib Treatment of Moderate to Severe Atopic Dermatitis on Skin Barrier Function[NCT05140239]20 participants (Anticipated)Observational2022-09-01Recruiting
A Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Parallel-Group, Nutritional Intervention Study to Examine the Clinical and Immunological Effects of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed[NCT04662619]273 participants (Actual)Interventional2020-12-18Active, not recruiting
Twice Daily Versus Twice Weekly Soak-and-Seal Baths in Pediatric Atopic Dermatitis: A Randomized, Single-blinded, Prospective Crossover Controlled Trial[NCT03397979]63 participants (Actual)Interventional2011-11-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for azathioprine and Eczema, Atopic

ArticleYear
The use of azathioprine in atopic dermatitis: A review.
    Dermatologic therapy, 2022, Volume: 35, Issue:9

    Topics: Azathioprine; Dermatitis, Atopic; Drug-Related Side Effects and Adverse Reactions; Humans; Immunosup

2022
Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis: A Systematic Review and Network Meta-analysis.
    JAMA dermatology, 2020, 06-01, Volume: 156, Issue:6

    Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Cyclosporine; Dermatitis, Atopic; Dermatolog

2020
Long-Term Treatment of Atopic Dermatitis.
    Dermatologic clinics, 2017, Volume: 35, Issue:3

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Azathioprine; Baths; Calcineurin Inhibitors; Cyc

2017
Atopic dermatitis: phototherapy and systemic therapy.
    Seminars in cutaneous medicine and surgery, 2017, Volume: 36, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Cyclosporine; Dermatitis, A

2017
Atopic dermatitis.
    Nature reviews. Disease primers, 2018, 06-21, Volume: 4, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Azathioprine; Boron Compounds; Bridged Bicyclo Com

2018
Atopic dermatitis.
    Nature reviews. Disease primers, 2018, 06-21, Volume: 4, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Azathioprine; Boron Compounds; Bridged Bicyclo Com

2018
Atopic dermatitis.
    Nature reviews. Disease primers, 2018, 06-21, Volume: 4, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Azathioprine; Boron Compounds; Bridged Bicyclo Com

2018
Atopic dermatitis.
    Nature reviews. Disease primers, 2018, 06-21, Volume: 4, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Azathioprine; Boron Compounds; Bridged Bicyclo Com

2018
What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention.
    Clinical and experimental dermatology, 2019, Volume: 44, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Anti-Allergic Agents; Azathi

2019
Novel systemic therapies in atopic dermatitis: what do we need to fulfil the promise of a treatment revolution?
    F1000Research, 2019, Volume: 8

    Topics: Azathioprine; Cyclosporine; Dermatitis, Atopic; Humans; Methotrexate; Randomized Controlled Trials a

2019
Efficacy and safety of systemic treatments for moderate-to-severe atopic dermatitis: a systematic review.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:2

    Topics: Azathioprine; Cyclosporine; Dermatitis, Atopic; Glucocorticoids; Humans; Immunosuppressive Agents; I

2014
Systemic Agents for Severe Atopic Dermatitis in Children.
    Paediatric drugs, 2015, Volume: 17, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized;

2015
Guidelines for the Management of Atopic Dermatitis in Singapore.
    Annals of the Academy of Medicine, Singapore, 2016, Volume: 45, Issue:10

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Calcineurin

2016
Non-topical management of recalcitrant paediatric atopic dermatitis.
    Archives of disease in childhood, 2017, Volume: 102, Issue:7

    Topics: Azathioprine; Child; Cyclosporine; Dermatitis, Atopic; Dermatologic Agents; Humans; Immunosuppressiv

2017
Systemic therapies for pediatric atopic dermatitis: a review for the primary care physician.
    Pediatric annals, 2009, Volume: 38, Issue:7

    Topics: Algorithms; Anti-Bacterial Agents; Antiviral Agents; Azathioprine; Child; Child, Preschool; Cyclospo

2009
Systemic therapy of atopic dermatitis in children and adults.
    Current problems in dermatology, 2011, Volume: 41

    Topics: Adrenal Cortex Hormones; Adult; Alitretinoin; Antibodies, Monoclonal; Azathioprine; Child; Cyclospor

2011
Update on systemic therapies for atopic dermatitis.
    Current opinion in allergy and clinical immunology, 2012, Volume: 12, Issue:4

    Topics: Azathioprine; Cyclosporine; Dermatitis, Atopic; Enzyme Inhibitors; Female; Humans; Immunosuppressive

2012
Management of severe atopic dermatitis in children.
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:10

    Topics: Administration, Cutaneous; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine

2012
[Systemic therapy of atopic dermatitis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:10

    Topics: Adjuvants, Immunologic; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Animals; Anti-Bacte

2003
[How should severe and chronic atopic dermatitis in children be managed?].
    Annales de dermatologie et de venereologie, 2005, Volume: 132 Spec No 1

    Topics: Azathioprine; Child; Chronic Disease; Dermatitis, Atopic; Humans; Immunologic Factors; Immunosuppres

2005
[How should severe and chronic atopic dermatitis be managed in children?].
    Annales de dermatologie et de venereologie, 2005, Volume: 132 Spec No 1

    Topics: Azathioprine; Child; Chronic Disease; Cyclosporine; Dermatitis, Atopic; Humans; Immunologic Factors;

2005
Azathioprine for atopic dermatitis.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:5

    Topics: Azathioprine; Dermatitis, Atopic; Dermatologic Agents; Humans; Immunosuppressive Agents; Mercaptopur

2001

Trials

7 trials available for azathioprine and Eczema, Atopic

ArticleYear
Methotrexate and azathioprine for severe atopic dermatitis: a 5-year follow-up study of a randomized controlled trial.
    The British journal of dermatology, 2018, Volume: 178, Issue:6

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Dermatologic Agents; Drug Administration Schedule; Drug Sub

2018
Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment.
    The British journal of dermatology, 2017, Volume: 177, Issue:6

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Female; Filaggrin Proteins; Humans; Immunosuppressive Agent

2017
A randomized trial of methotrexate versus azathioprine for severe atopic eczema.
    The Journal of allergy and clinical immunology, 2011, Volume: 128, Issue:2

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Female; Humans; Immunosuppressive Agents; Male; Methotrexat

2011
Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial.
    The British journal of dermatology, 2002, Volume: 147, Issue:2

    Topics: Adolescent; Adult; Aged; Azathioprine; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method;

2002
[Azatropin in severe atopic dermatitis: 24 cases].
    Annales de dermatologie et de venereologie, 2005, Volume: 132, Issue:2

    Topics: Adult; Azathioprine; Child; Dermatitis, Atopic; Female; Humans; Immunosuppressive Agents; Male; Retr

2005
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.
    Lancet (London, England), 2006, Mar-11, Volume: 367, Issue:9513

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Immu

2006
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.
    Lancet (London, England), 2006, Mar-11, Volume: 367, Issue:9513

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Immu

2006
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.
    Lancet (London, England), 2006, Mar-11, Volume: 367, Issue:9513

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Immu

2006
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.
    Lancet (London, England), 2006, Mar-11, Volume: 367, Issue:9513

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Immu

2006
Treatment of canine atopic dermatitis with azathioprine: a pilot study.
    The Veterinary record, 2007, Apr-14, Volume: 160, Issue:15

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Azathioprine; Dermatitis, Atopic; Dog Diseases;

2007

Other Studies

51 other studies available for azathioprine and Eczema, Atopic

ArticleYear
Systemic treatment of children and adolescents with atopic dermatitis aged ≥2 years: a Delphi consensus project mapping expert opinion in Northern Europe.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:11

    Topics: Adolescent; Azathioprine; Biological Products; Child; Child, Preschool; Cyclosporine; Delphi Techniq

2022
European guideline (EuroGuiDerm) on atopic eczema: part I - systemic therapy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:9

    Topics: Adolescent; Azathioprine; Child; Cyclosporine; Dermatitis, Atopic; Eczema; Humans; Immunosuppressive

2022
Systemic treatment for severe atopic dermatitis in children: a case series.
    Boletin medico del Hospital Infantil de Mexico, 2022, Volume: 79, Issue:5

    Topics: Azathioprine; Child; Child, Preschool; Cyclosporine; Dermatitis, Atopic; Humans; Methotrexate; Mycop

2022
Adverse event monitoring in patients on oral systemic medications for inflammatory skin disease.
    Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:6

    Topics: Azathioprine; Cross-Sectional Studies; Cyclosporine; Dermatitis, Atopic; Drug Eruptions; Drug Monito

2020
Drug survival rates and reasons for drug discontinuation in patients with atopic dermatitis: a retrospective study of adult outpatients.
    European journal of dermatology : EJD, 2021, Apr-01, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Azathioprine; Child; Child, Preschool; C

2021
Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine.
    The Journal of dermatological treatment, 2018, Volume: 29, Issue:4

    Topics: Adult; Azathioprine; Chromatography, High Pressure Liquid; Dermatitis, Atopic; Eczema; Female; Guani

2018
Methotrexate versus azathioprine in patients with atopic dermatitis: 2-year follow-up data.
    The Journal of allergy and clinical immunology, 2018, Volume: 141, Issue:2

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Female; Filaggrin Proteins; Follow-Up Studies; Humans; Inte

2018
Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema.
    Acta dermato-venereologica, 2018, Mar-13, Volume: 98, Issue:3

    Topics: Adult; Allopurinol; Azathioprine; Chronic Disease; Dermatitis, Atopic; Drug Therapy, Combination; Ec

2018
[Current and upcoming treatments of adult atopic dermatitis].
    Annales de dermatologie et de venereologie, 2017, Volume: 144 Suppl 5

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Boron Compounds; Bri

2017
Use of oral immunosuppressive drugs in the treatment of atopic dermatitis in the Netherlands.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:8

    Topics: Administration, Oral; Azathioprine; Cyclosporine; Databases, Factual; Dermatitis, Atopic; Drug Presc

2018
UVA-1 phototherapy for the management of atopic dermatitis: a large retrospective study conducted in a low-middle income country.
    International journal of dermatology, 2018, Volume: 57, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Colombia; Dermatitis, Atopic; Develo

2018
Building the evidence base for current systemic treatments for severe, chronic atopic dermatitis: methotrexate vs. azathioprine.
    The British journal of dermatology, 2018, Volume: 178, Issue:6

    Topics: Azathioprine; Dermatitis, Atopic; Follow-Up Studies; Humans; Methotrexate; Mycophenolic Acid

2018
A Retrospective Study of Systemic Treatment of Severe Atopic Dermatitis With Azathioprine: Effectiveness and Tolerance in 11 Pediatric Patients.
    Actas dermo-sifiliograficas, 2019, Volume: 110, Issue:3

    Topics: Adolescent; Azathioprine; Child; Dermatitis, Atopic; Female; Humans; Immunosuppressive Agents; Male;

2019
Azathioprine in the Treatment of Severe Pediatric Atopic Dermatitis: Experience in a Referral Hospital in Spain.
    Actas dermo-sifiliograficas, 2019, Volume: 110, Issue:3

    Topics: Azathioprine; Dermatitis, Atopic; Humans; Referral and Consultation; Spain

2019
Systemic therapies for severe atopic dermatitis in children and adults.
    The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:3

    Topics: Adult; Azathioprine; Child; Cyclosporine; Dermatitis, Atopic; Humans; Immunosuppressive Agents; Male

2013
Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:2

    Topics: Anti-Infective Agents; Azathioprine; Cyclosporine; Dermatitis, Atopic; Histamine Antagonists; Humans

2014
Outcome of treatment with azathioprine in severe atopic dermatitis: a 5-year retrospective study of adult outpatients.
    The British journal of dermatology, 2015, Volume: 172, Issue:4

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Dermatologic Agents; Drug Administration Schedule; Female;

2015
The adverse effect profile of oral azathioprine in pediatric atopic dermatitis, and recommendations for monitoring.
    Journal of the American Academy of Dermatology, 2015, Volume: 72, Issue:1

    Topics: Administration, Oral; Azathioprine; Child; Dermatitis, Atopic; Drug Monitoring; Drug-Related Side Ef

2015
Ten years experience with oral immunosuppressive treatment in adult patients with atopic dermatitis in two academic centres.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:10

    Topics: Academic Medical Centers; Administration, Oral; Adult; Azathioprine; Cyclosporine; Dermatitis, Atopi

2015
Increased liver enzyme levels during azathioprine treatment: beware of concomitant use of proton pump inhibitors.
    The British journal of dermatology, 2015, Volume: 173, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Alanine Transaminase; Azathioprine; Dermatitis, Atopi

2015
The anti-IL-4 receptor alpha antibody dupilumab: facing a new era in treating atopic dermatitis.
    Expert opinion on biological therapy, 2015, Volume: 15, Issue:11

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials as Topic; C

2015
Drug survival for azathioprine and enteric-coated mycophenolate sodium in a long-term daily practice cohort of adult patients with atopic dermatitis.
    The British journal of dermatology, 2016, Volume: 175, Issue:1

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Drug Resistance; Drug Substitution; Female; Humans; Kaplan-

2016
Long-term Use of Systemic Treatments for Moderate-to-Severe Atopic Dermatitis in Adults: A Monocentric Retrospective Study.
    Acta dermato-venereologica, 2016, Aug-23, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporine; Dermatitis, Atopic; Drug Therapy, Combination;

2016
Effectiveness of azathioprine pulse therapy in prolonging remission of psoriasis.
    Dermatologic therapy, 2017, Volume: 30, Issue:1

    Topics: Azathioprine; Dermatitis, Atopic; Eczema; Humans; Psoriasis

2017
Editorial on Guidelines for the Management of Atopic Dermatitis in Singapore.
    Annals of the Academy of Medicine, Singapore, 2016, Volume: 45, Issue:10

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Azathioprine; Calcineurin Inhibitors; Cyclospori

2016
Hospital-diagnosed atopic dermatitis and long-term risk of myocardial infarction: a population-based follow-up study.
    BMJ open, 2016, 11-11, Volume: 6, Issue:11

    Topics: Adult; Aged; Ambulatory Care; Azathioprine; Case-Control Studies; Cyclosporine; Denmark; Dermatitis,

2016
Prescribing practices for systemic agents in the treatment of severe pediatric atopic dermatitis in the US and Canada: The PeDRA TREAT survey.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:2

    Topics: Adult; Azathioprine; Canada; Child; Cyclosporine; Dermatitis, Atopic; Dermatology; Drug Prescription

2017
Usage and effectiveness of systemic treatments in adults with severe atopic eczema: First results of the German Atopic Eczema Registry TREATgermany.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2017, Volume: 15, Issue:1

    Topics: Adult; Alitretinoin; Anti-Inflammatory Agents; Azathioprine; Cyclosporine; Dermatitis, Atopic; Femal

2017
Further experience of using azathioprine in the treatment of severe atopic dermatitis.
    Clinical and experimental dermatology, 2008, Volume: 33, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Dermatitis, Atopic; Female; Follow-Up Studies; Humans;

2008
Efficacy and tolerability at 3 and 6 months following use of azathioprine for recalcitrant atopic dermatitis in children and young adults.
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:3

    Topics: Adolescent; Age Factors; Azathioprine; Child; Dermatitis, Atopic; Dose-Response Relationship, Drug;

2009
Optimizing clinical use of azathioprine with newer pharmacogenetic data.
    Archives of dermatology, 2009, Volume: 145, Issue:6

    Topics: Azathioprine; Dermatitis, Atopic; Dose-Response Relationship, Drug; Drug Administration Schedule; Fe

2009
TPMT*26 (208F-->L), a novel mutation detected in a Chinese.
    British journal of clinical pharmacology, 2009, Volume: 68, Issue:1

    Topics: Asian People; Azathioprine; Dermatitis, Atopic; Genotype; Humans; Immunosuppressive Agents; Male; Me

2009
[Safety of azathioprine therapy adjusted to thiopurine methyltransferase activity in the treatment of infantile atopic dermatitis. Report on 7 cases].
    Actas dermo-sifiliograficas, 2010, Volume: 101, Issue:5

    Topics: Adolescent; Azathioprine; Child; Dermatitis, Atopic; Female; Humans; Immunosuppressive Agents; Male;

2010
Acute pancreatitis and erythema nodosum associated with azathioprine.
    QJM : monthly journal of the Association of Physicians, 2012, Volume: 105, Issue:4

    Topics: Acute Disease; Azathioprine; Dermatitis, Atopic; Dermatologic Agents; Erythema Nodosum; Humans; Immu

2012
Life threatening myelotoxicity secondary to azathioprine in a patient with atopic eczema and normal thiopurine methyltransferase activity.
    BMJ (Clinical research ed.), 2011, Mar-25, Volume: 342

    Topics: Adult; Azathioprine; Bone Marrow Diseases; Dermatitis, Atopic; Humans; Immunosuppressive Agents; Mal

2011
Clinically integrated care. Shared care/blame arrangements.
    BMJ (Clinical research ed.), 2011, Apr-18, Volume: 342

    Topics: Azathioprine; Bone Marrow Diseases; Dermatitis, Atopic; Drug Monitoring; Humans; Immunosuppressive A

2011
Oral azathioprine for recalcitrant pediatric atopic dermatitis: clinical response and thiopurine monitoring.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:1

    Topics: Administration, Oral; Adolescent; Azathioprine; Child; Child, Preschool; Dermatitis, Atopic; Female;

2013
A retrospective evaluation of azathioprine in severe childhood atopic eczema, using thiopurine methyltransferase levels to exclude patients at high risk of myelosuppression.
    The British journal of dermatology, 2002, Volume: 147, Issue:2

    Topics: Azathioprine; Biomarkers; Child; Child, Preschool; Dermatitis, Atopic; Drug Therapy, Combination; Er

2002
[Drug-induced alveolitis associated with infliximab/azathioprine therapy].
    Pneumologie (Stuttgart, Germany), 2008, Volume: 62, Issue:4

    Topics: Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Derm

2008
Hypereosinophilia, hyper-IgE syndrome, and atopic dermatitis in a toddler with food hypersensitivity.
    Journal of investigational allergology & clinical immunology, 2008, Volume: 18, Issue:2

    Topics: Azathioprine; Bone Marrow Examination; Cell Separation; Combined Modality Therapy; Dermatitis, Atopi

2008
Retrospective review of the use of azathioprine in severe atopic dermatitis.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:4

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Dermatitis, Atopic;

1996
Kaposi's sarcoma during immunosuppressive therapy for atopic dermatitis.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:2

    Topics: Administration, Topical; Aged; Anti-Inflammatory Agents; Azathioprine; Betamethasone Valerate; CD4-P

1997
Azathioprine in dermatology: a survey of current practice in the U.K.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Topics: Azathioprine; Bone Marrow; Dermatitis, Atopic; Dermatology; Drug Administration Schedule; Health Car

1997
The use of azathioprine in severe adult atopic eczema.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1998, Volume: 11, Issue:2

    Topics: Adult; Antimetabolites; Azathioprine; Clinical Trials as Topic; Dermatitis, Atopic; Drug Evaluation;

1998
Treatment of common skin complaints--changing referral patterns.
    Irish medical journal, 1997, Volume: 90, Issue:7

    Topics: Acne Vulgaris; Anthralin; Azathioprine; Dermatitis, Atopic; Dermatology; Diagnosis, Differential; Ec

1997
Clinical improvement and significant reduction of total serum IgE in patients suffering from severe atopic dermatitis treated with oral azathioprine.
    The Australasian journal of dermatology, 2002, Volume: 43, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Azathioprine; Dermatitis, Atopic; Female; Huma

2002
[Azathiopurine in treatment of atopic dermatitis and its influence to IgE level and various kinds of immunological tests (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1975, Volume: 85, Issue:6

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Humans; Immunoglobulin E; Male

1975
Recurrent facial herpes associated with Chinese herbal remedy.
    Lancet (London, England), 1991, Jul-06, Volume: 338, Issue:8758

    Topics: Adult; Azathioprine; Dermatitis, Atopic; Drugs, Chinese Herbal; Facial Dermatoses; Herpes Simplex; H

1991
The effect of some immunomodulating agents on the sensitization phase of experimental contact allergic reactions.
    International archives of allergy and applied immunology, 1986, Volume: 79, Issue:2

    Topics: Animals; Azathioprine; Cyclophosphamide; Dermatitis, Atopic; Dermatitis, Contact; Dose-Response Rela

1986
Immunoglobulin E in "healed" atopic dermatitis and after treatment with corticosteroids and azathioprine.
    The British journal of dermatology, 1970, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Dermatitis, Atopic; Eczema; Female; gamma-Globulins; Humans;

1970
Differential effect of immunosuppressive agents on T and B lymphocytes.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Animals; Antilymphocyte Serum; Azathioprine; B-Lymphocytes; Bacterial Infections; Concanavalin A; De

1974