Page last updated: 2024-10-23

azathioprine and Ear Diseases

azathioprine has been researched along with Ear Diseases in 7 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Ear Diseases: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

Research Excerpts

ExcerptRelevanceReference
"Hypersensitivity mimicking gastroenteritis is a rare complication of azathioprine therapy for which the mechanism is unknown."7.69Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine. ( Astier, A; Autegarden, JE; Godeau, B; Leynadier, F; Paul, M; Schaeffer, A, 1995)
"Hypersensitivity mimicking gastroenteritis is a rare complication of azathioprine therapy for which the mechanism is unknown."3.69Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine. ( Astier, A; Autegarden, JE; Godeau, B; Leynadier, F; Paul, M; Schaeffer, A, 1995)
"Relapsing polychondritis is a rare disease probably of auto-immune etiology comprising inflammatory involvement of cartilage as well as phenomena of vasculitis."1.30ENT manifestations of relapsing polychondritis. ( Gerard, JM; Gerard, M; Namias, B; Rampelberg, O, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fernández, S1
España, A1
Navedo, M1
Barona, L1
Godeau, B1
Paul, M1
Autegarden, JE1
Leynadier, F1
Astier, A1
Schaeffer, A1
Rampelberg, O1
Gerard, JM1
Namias, B1
Gerard, M1
Bulman, CH1
Kane, RJ1
Srivastva, VN1
Wolff, SM2
Fauci, AS2
Horn, RG1
Dale, DC1
Bourdinière, J1
Jezéquel, J1
de Labarthe, B1
Ramée, MP1
Bourguet, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901]Phase 260 participants Interventional1999-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for azathioprine and Ear Diseases

ArticleYear
Study of oral, ear, nose and throat involvement in pemphigus vulgaris by endoscopic examination.
    The British journal of dermatology, 2012, Volume: 167, Issue:5

    Topics: Azathioprine; Drug Therapy, Combination; Ear Diseases; Endoscopy; Glucocorticoids; Humans; Immunosup

2012
Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine.
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:1

    Topics: Adult; Azathioprine; Diagnosis, Differential; Diarrhea; Ear Diseases; Gastroenteritis; Humans; Kerat

1995
ENT manifestations of relapsing polychondritis.
    Acta oto-rhino-laryngologica Belgica, 1997, Volume: 51, Issue:2

    Topics: Anti-Inflammatory Agents; Azathioprine; Cochlear Diseases; Ear Diseases; Ear, External; Humans; Immu

1997
The ENT manifestations of systemic vasculitis.
    The Journal of laryngology and otology, 1985, Volume: 99, Issue:9

    Topics: Azathioprine; Deafness; Ear Diseases; Female; Humans; Male; Middle Aged; Nose Diseases; Otitis Media

1985
Wegener's granulomatosis.
    Annals of internal medicine, 1974, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Diagnosis, Differe

1974
[Wegener's granulomatosis in otological form. (Diagnosis and evolution during immunodepressive treatment)].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1973, Volume: 90, Issue:3

    Topics: Azathioprine; Betamethasone; Cortisone; Cyclophosphamide; Deafness; Ear Diseases; Eye Manifestations

1973
Wegener's granulomatosis: studies in eighteen patients and a review of the literature.
    Medicine, 1973, Volume: 52, Issue:6

    Topics: Adult; Aged; Azathioprine; Biopsy; Corneal Ulcer; Cyclophosphamide; Diagnosis, Differential; Ear Dis

1973