Page last updated: 2024-10-23

azathioprine and Dyspnea

azathioprine has been researched along with Dyspnea in 25 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Dyspnea: Difficult or labored breathing.

Research Excerpts

ExcerptRelevanceReference
"We identified all patients treated for PM/DM-ILD and assessed cyclophosphamide (CYC), azathioprine (AZA) and mycophenolate (MMF) when used as first-line steroid sparing therapy for effects on pulmonary function variables, dyspnea and tolerance at six and twelve months."3.79A retrospective review of clinical features and treatment outcomes in steroid-resistant interstitial lung disease from polymyositis/dermatomyositis. ( Arrossi, V; Chapman, JT; Culver, DA; Mira-Avendano, IC; Parambil, JG; Xu, M; Yadav, R, 2013)
" Patients were treated with azathioprine and low-dose prednisone if they had progressive pulmonary symptoms (deterioration in the dyspnea score) or poor or deteriorating lung function."3.72Experience with azathioprine in systemic sclerosis associated with interstitial lung disease. ( Cassim, B; Dheda, K; Lalloo, UG; Mody, GM, 2004)
"Infection and disease exacerbation are the leading reasons for ICU admission in systemic rheumatic diseases."1.72Determination of the main causes, outcome, and prognostic factors of patients with rheumatologic diseases admitted to the medical intensive care unit in Southern Iran. ( Arjmand, M; Fallahi, MJ; Shahriarirad, R; Shenavandeh, S, 2022)
"Pulmonary lymphomatoid granulomatosis (PLG) is a rare angiocentric and angiodestructive EBV-associated lymphoproliferative disorder which almost always affects the lungs."1.56An atypical case of a pulmonary mass in an immunocompromised patient. ( Bode, H; Bos, S; Cardinaels, N; Tousseyn, T; Van Bleyenbergh, P; Van Rompaey, W, 2020)
"Later, patient developed posterior reversible encephalopathy syndrome (PRES)."1.56Idiopathic pulmonary hemosiderosis - A rare cause of chronic anemia. ( Ahmed, R; Butt, A; Iqbal, N; Khan, JA; Khan, O; Rahman, AJ; Sheikh, MDA, 2020)
"Its presentation with interstitial lung disease alters its prognosis."1.51Antisynthetase syndrome presenting as interstitial lung disease: a case report. ( Badshah, A; Haider, I; Humayun, M; Pervez, S, 2019)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's1 (4.00)18.2507
2000's5 (20.00)29.6817
2010's11 (44.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Arjmand, M1
Shahriarirad, R1
Shenavandeh, S1
Fallahi, MJ1
Cardinaels, N1
Van Rompaey, W1
Bos, S1
Bode, H1
Tousseyn, T1
Van Bleyenbergh, P1
Ibraheim, MK1
Govindu, RR1
Bozzalla Cassione, E1
Zanframundo, G1
Biglia, A1
Codullo, V1
Montecucco, C1
Cavagna, L1
Butt, A1
Ahmed, R1
Sheikh, MDA1
Khan, O1
Iqbal, N1
Rahman, AJ1
Khan, JA1
Ron, R1
Ruz-Caracuel, I1
García, E1
Montes-Ramírez, ML1
Badshah, A1
Haider, I1
Pervez, S1
Humayun, M1
Mira-Avendano, IC1
Parambil, JG1
Yadav, R1
Arrossi, V1
Xu, M1
Chapman, JT1
Culver, DA1
Abbey, A1
Elsmore, AC1
Ataya, A1
Faruqi, I1
Salgado, JC1
Morales, E1
Rabasco, C1
Panizo, N1
Gutierrez, E1
Martinez, MA1
Toldos, O1
Praga, M1
Pathria, M1
Urbine, D1
Zumberg, MS1
Guarderas, J1
Papadopoulou, D1
Valsamidis, K1
Kamargiannis, N1
Bowling, MR1
Cauthen, CG1
Perry, CD1
Patel, NP1
Bergman, S1
Link, KM1
Sane, AC1
Conforti, JF1
Henes, J1
Horger, M1
Kanz, L1
Kötter, I1
Adema, AY1
Schilder, AM1
Schreuder, TC1
Grünberg, K1
Bultink, IE1
Mulder, CJ1
Ishida, T1
Kotani, T1
Takeuchi, T1
Makino, S1
Baughman, RP1
Nunes, H1
Sweiss, NJ1
Lower, EE1
Tack, DK1
Paisansinsup, T1
Amin, S1
Dheda, K1
Lalloo, UG1
Cassim, B1
Mody, GM1
Stiefelhagen, P1
Hirata, Y1
Takizawa, H1
Okazaki, H1
Yoshida, A1
Ishii, A1
Kohno, T1
Nakajima, J1
Oka, T1
Ito, K1
Clarke, SW1
Kendall, MJ1
Rubin, G1
Baume, P1
Vandenberg, R1
Benson, MK1
Hughes, DT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endobronchial Mucosal Biopsy in Patients With Suspected Pulmonary Sarcoidosis[NCT04904939]20 participants (Actual)Interventional2020-05-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for azathioprine and Dyspnea

ArticleYear
Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency.
    BMJ case reports, 2016, Jun-22, Volume: 2016

    Topics: Azathioprine; Common Variable Immunodeficiency; Cough; Dyspnea; Female; Humans; Immunoglobulins, Int

2016
Established and experimental medical therapy of pulmonary sarcoidosis.
    The European respiratory journal, 2013, Volume: 41, Issue:6

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials

2013

Other Studies

23 other studies available for azathioprine and Dyspnea

ArticleYear
Determination of the main causes, outcome, and prognostic factors of patients with rheumatologic diseases admitted to the medical intensive care unit in Southern Iran.
    Clinical rheumatology, 2022, Volume: 41, Issue:12

    Topics: Arthritis, Rheumatoid; Azathioprine; Disease Progression; Dyspnea; Female; Hospital Mortality; Human

2022
An atypical case of a pulmonary mass in an immunocompromised patient.
    Acta clinica Belgica, 2020, Volume: 75, Issue:5

    Topics: Aged; Azathioprine; Biopsy; Bronchoscopy; Chest Pain; Crohn Disease; Dyspnea; Endosonography; Female

2020
Rheumatoid Arthritis-Associated Interstitial Lung Disease.
    The American journal of the medical sciences, 2020, Volume: 359, Issue:5

    Topics: Arthritis, Rheumatoid; Azathioprine; Dyspnea; Hand; Humans; Lung; Lung Diseases, Interstitial; Male;

2020
COVID-19 infection in a northern-Italian cohort of systemic lupus erythematosus assessed by telemedicine.
    Annals of the rheumatic diseases, 2020, Volume: 79, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Azathioprine; Betacoronavirus; Clinical Labora

2020
Idiopathic pulmonary hemosiderosis - A rare cause of chronic anemia.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020, Jun-09, Volume: 90, Issue:2

    Topics: Adult; Anemia; Azathioprine; Biopsy; Bronchoscopy; Child; Chronic Disease; Drug Therapy, Combination

2020
IgG4-related disease in a patient with HIV infection.
    BMJ case reports, 2019, Apr-14, Volume: 12, Issue:4

    Topics: Azathioprine; Dyspnea; Glucocorticoids; HIV Infections; Humans; Immunoglobulin G; Immunoglobulin G4-

2019
Antisynthetase syndrome presenting as interstitial lung disease: a case report.
    Journal of medical case reports, 2019, Aug-04, Volume: 13, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Creatine Kinase; Diagnosis, Differenti

2019
A retrospective review of clinical features and treatment outcomes in steroid-resistant interstitial lung disease from polymyositis/dermatomyositis.
    Respiratory medicine, 2013, Volume: 107, Issue:6

    Topics: Adult; Azathioprine; Cyclophosphamide; Dermatomyositis; Drug Administration Schedule; Drug Resistanc

2013
Shortness of breath in a patient with inflammatory bowel disease.
    BMJ case reports, 2014, Oct-09, Volume: 2014

    Topics: Azathioprine; Crohn Disease; Cytomegalovirus; Cytomegalovirus Infections; Dyspnea; Humans; Immunocom

2014
A 41-year-old woman with shortness of breath and history of rash and recurrent laryngeal edema.
    Chest, 2015, Volume: 147, Issue:2

    Topics: Adult; Azathioprine; Complement System Proteins; Disease Progression; Dyspnea; Female; Glucocorticoi

2015
Mesangial nephropathy and anti-synthetase syndrome: An odd association.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2015, Volume: 35, Issue:4

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination; Dyspnea; Edem

2015
Endoscopy Dyspnea and Ulcerative Colitis.
    JAMA otolaryngology-- head & neck surgery, 2016, 12-01, Volume: 142, Issue:12

    Topics: Azathioprine; Colitis, Ulcerative; Dyspnea; Epiglottitis; Female; Humans; Immunocompromised Host; Im

2016
Pulmonary extramedullary hematopoiesis.
    Journal of thoracic imaging, 2008, Volume: 23, Issue:2

    Topics: Anemia, Hemolytic; Antirheumatic Agents; Arthritis; Azathioprine; Biopsy, Fine-Needle; Diagnosis, Di

2008
[56-year-old patient with leg paresis, pulmonary infiltrates, and eosinophilia--Case 08/2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:44

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Azathioprine; Churg-Strauss Syndrom

2009
Ascites as the presenting symptom in a patient with Churg-Strauss syndrome.
    Journal of gastrointestinal and liver diseases : JGLD, 2010, Volume: 19, Issue:2

    Topics: Aged; Ascites; Asthma; Azathioprine; Biopsy; Churg-Strauss Syndrome; Drug Therapy, Combination; Dysp

2010
Pulmonary toxicity after initiation of azathioprine for treatment of interstitial pneumonia in a patient with rheumatoid arthritis.
    The Journal of rheumatology, 2012, Volume: 39, Issue:5

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Dyspnea; Humans; Lung Diseases, Int

2012
44-year-old woman with fatigue and dyspnea.
    Mayo Clinic proceedings, 2003, Volume: 78, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Dyspnea; Fatigue; Female; Humans; Immunosuppressive A

2003
Experience with azathioprine in systemic sclerosis associated with interstitial lung disease.
    Clinical rheumatology, 2004, Volume: 23, Issue:4

    Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspnea; Female; Glucocor

2004
[Increasing dyspnea: myocardial infarction anamnesis led to wrong track].
    MMW Fortschritte der Medizin, 2005, Feb-24, Volume: 147, Issue:8

    Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Diagnosis, Differential; Dyspnea; Female; Humans; Immun

2005
[Interstitial pneumonia with Sjögren's syndrome: successful treatment with steroids and an immunosuppressant].
    Nihon Kyobu Shikkan Gakkai zasshi, 1997, Volume: 35, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Drug Therapy, Combination; Dyspnea; Female; Humans; I

1997
Adrenergic blockade in hypertension.
    Lancet (London, England), 1972, May-20, Volume: 1, Issue:7760

    Topics: Autoimmune Diseases; Azathioprine; Dyspnea; Female; Hepatitis; Humans; Middle Aged; Myasthenia Gravi

1972
Azathioprin nd acute restrictive lung disese.
    Australian and New Zealand journal of medicine, 1972, Volume: 2, Issue:3

    Topics: Acute Disease; Adult; Azathioprine; Carbon Monoxide; Colitis, Ulcerative; Cough; Dyspnea; Humans; Lu

1972
Serial pulmonary function tests in fibrosing alveolitis.
    British journal of diseases of the chest, 1972, Volume: 66, Issue:1

    Topics: Adult; Azathioprine; Biopsy; Dyspnea; Female; Humans; Lung; Male; Middle Aged; Prednisone; Pulmonary

1972