azathioprine has been researched along with Drug Overdose in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 14-year-old girl with systemic lupus erythematosus presented with a mixed overdose of paracetamol, ibuprofen and azathioprine (1500 mg) following a deliberate self-harm attempt." | 2.49 | Intentional overdose of azathioprine in a patient with systemic lupus erythematosus. ( Khan, AM; Mahmood, K; Martin, K; Ramanan, AV, 2013) |
| " Moreover, acute liver failure after multiple dosing of azathioprine was investigated in a patient case study by use of own clinical data." | 1.46 | Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients. ( Blank, LM; Castell, JV; Conde, I; Cordes, H; Kuepfer, L; Thiel, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahmood, K | 1 |
| Khan, AM | 1 |
| Ramanan, AV | 1 |
| Martin, K | 1 |
| Gregoriano, C | 1 |
| Ceschi, A | 1 |
| Rauber-Lüthy, C | 1 |
| Kupferschmidt, H | 1 |
| Banner, NR | 1 |
| Krähenbühl, S | 1 |
| Taegtmeyer, AB | 1 |
| Thiel, C | 1 |
| Cordes, H | 1 |
| Conde, I | 1 |
| Castell, JV | 1 |
| Blank, LM | 1 |
| Kuepfer, L | 1 |
1 review available for azathioprine and Drug Overdose
| Article | Year |
|---|---|
Intentional overdose of azathioprine in a patient with systemic lupus erythematosus.
Topics: Acetaminophen; Adolescent; Affective Disorders, Psychotic; Anti-Inflammatory Agents, Non-Steroidal; | 2013 |
2 other studies available for azathioprine and Drug Overdose
| Article | Year |
|---|---|
Acute thiopurine overdose: analysis of reports to a National Poison Centre 1995-2013.
Topics: Adult; Ambulatory Care; Antimetabolites; Azathioprine; Charcoal; Child, Preschool; Drug Overdose; Fe | 2014 |
Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.
Topics: Adult; Animals; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Overdose; Drug-Related Si | 2017 |