azathioprine has been researched along with Drug Hypersensitivity in 123 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter." | 9.04 | Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975) |
| "Azathioprine (AZA) drug hypersensitivity reaction (DHR) is an uncommon yet potentially lethal condition that often goes unrecognised in patients with anti-Neutrophil Cytoplasmic Antibody (ANCA) associated vasculitis (AAV)." | 8.31 | Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis. ( Au Peh, C; Carroll, RP; Fleet, AP; Hissaria, P; Salehi, T, 2023) |
| "Erythema nodosum and pustules are rarely reported manifestations of azathioprine hypersensitivity." | 7.74 | Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. ( Aractingi, S; Beaugerie, L; Cosnes, J; de Fonclare, AL; Duriez, P; Khosrotehrani, K, 2007) |
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 7.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "The association of fever, nasal congestion and reversible rise in serum creatinine in a patient receiving azathioprine is reported." | 7.68 | Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy. ( Donckerwolcke, RA; Vande Walle, JG, 1990) |
| "We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency." | 7.68 | Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992) |
| "Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills." | 7.68 | Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990) |
| "A patient with myasthenia gravis is described who exhibited hypersensitivity including an apparent acute exacerbation of the underlying disorder when treated with azathioprine." | 7.67 | Hypersensitivity to azathioprine in myasthenia gravis. ( Corston, R; Watts, GF, 1984) |
| "We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder." | 7.65 | Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975) |
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 5.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| "Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis." | 5.33 | Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 5.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 5.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| "Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter." | 5.04 | Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975) |
| "Azathioprine (AZA) drug hypersensitivity reaction (DHR) is an uncommon yet potentially lethal condition that often goes unrecognised in patients with anti-Neutrophil Cytoplasmic Antibody (ANCA) associated vasculitis (AAV)." | 4.31 | Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis. ( Au Peh, C; Carroll, RP; Fleet, AP; Hissaria, P; Salehi, T, 2023) |
| "Erythema nodosum and pustules are rarely reported manifestations of azathioprine hypersensitivity." | 3.74 | Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. ( Aractingi, S; Beaugerie, L; Cosnes, J; de Fonclare, AL; Duriez, P; Khosrotehrani, K, 2007) |
| " Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug." | 3.73 | Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005) |
| "Approximately 10% of inflammatory bowel disease (IBD) patients receiving 6-mercaptopurine (6-MP) or azathioprine (AZA) develop drug hypersensitivity reactions necessitating early discontinuation of these traditional thiopurines." | 3.72 | Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. ( Abreu, MT; Dubinsky, MC; Feldman, EJ; Targan, SR; Vasiliauskas, EA, 2003) |
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 3.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency." | 3.68 | Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992) |
| "Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills." | 3.68 | Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990) |
| "The association of fever, nasal congestion and reversible rise in serum creatinine in a patient receiving azathioprine is reported." | 3.68 | Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy. ( Donckerwolcke, RA; Vande Walle, JG, 1990) |
| "A patient with myasthenia gravis is described who exhibited hypersensitivity including an apparent acute exacerbation of the underlying disorder when treated with azathioprine." | 3.67 | Hypersensitivity to azathioprine in myasthenia gravis. ( Corston, R; Watts, GF, 1984) |
| "We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder." | 3.65 | Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975) |
| "Autoimmune hepatitis is a rare chronic inflammatory liver disease, affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis at liver histology and good response to immunosuppressive treatment." | 2.55 | Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments. ( Mieli-Vergani, G; Terziroli Beretta-Piccoli, B; Vergani, D, 2017) |
| "Azathioprine is a drug commonly used for the treatment of inflammatory bowel disease, organ transplantation and various autoimmune diseases." | 2.40 | Cholestatic hepatocellular injury with azathioprine: a case report and review of the mechanisms of hepatotoxicity. ( Jewell, L; Lalor, E; Romagnuolo, J; Sadowski, DC; Thomson, AB, 1998) |
| " Adverse effects occur in about 15% of patients." | 2.40 | Azathioprine in inflammatory bowel disease, a safe alternative? ( Tanis, AA, 1998) |
| "Azathioprine was discontinued and an evaluation for sepsis was undertaken; all cultures were negative and the fever abated." | 2.39 | Azathioprine hypersensitivity-like reactions--a case report and a review of the literature. ( Gupta, AK; Knowles, SR; Sauder, D; Shear, NH, 1995) |
| "Our aim was to assess the cost-effectiveness of phenotyping-based dosing of TPMT activity, genotyping-based screening and no screening (reference) for patients treated with azathioprine." | 1.51 | Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis. ( Chatellier, G; Durand-Zaleski, I; Loriot, MA; Pallet, N; Zarca, K, 2019) |
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 1.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| " This study aims to detect TPMT polymorphisms and TPMT enzyme activity in Chinese SLE patients and to describe the association between TPMT genotypes and adverse effects of AZA." | 1.40 | Association of thiopurine methyltransferase status with azathioprine side effects in Chinese patients with systemic lupus erythematosus. ( Chen, D; Lian, F; Liang, L; Qiu, Q; Wang, Y; Xu, H; Yang, X; Ye, Y; Yuan, S; Zhan, Z, 2014) |
| "We describe a pediatric case of Sweet syndrome presenting 10 days after treatment with azathioprine." | 1.37 | Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis. ( Choe, YH; Jang, KT; Kim, MJ, 2011) |
| "Mercaptopurine was tolerated in 71% (12/17) with hepatotoxicity and in 68% (13/19) with arthralgia/myalgia during azathioprine treatment." | 1.35 | Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease. ( Almer, SH; Eriksson, A; Hindorf, U; Johansson, M; Kvifors, E, 2009) |
| "Sweet syndrome is a reactive, sterile, pustular dermatosis that occurs in association with infection, malignancy, or connective tissue disease or in response to the use of certain medications." | 1.35 | Sweet syndrome as a manifestation of azathioprine hypersensitivity. ( Brunner, KL; El-Azhary, RA; Gibson, LE, 2008) |
| "Twenty nine previously confirmed Crohn's disease (CD) (n = 14) and ulcerative colitis (UC) (n = 15) patients with a known previous (AZA) hypersensitivity reaction were studied prospectively." | 1.35 | Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease. ( Farkas, K; Lonovics, J; Molnar, T; Nagy, F; Nyari, T; Szepes, Z, 2008) |
| "Mercaptopurine was tolerated by 59% (36 of 61) of azathioprine-intolerant patients (median dose 1." | 1.35 | Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease. ( Arnott, ID; Hansoti, B; Lees, CW; Maan, AK; Satsangi, J, 2008) |
| "Two patients developed acute pancreatitis." | 1.34 | Thiopurine metabolite monitoring in paediatric inflammatory bowel disease. ( Bohane, TD; Day, AS; Lee, D; Naidoo, D; Ooi, CY, 2007) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 1.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis." | 1.33 | Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 1.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| "Dapsone was the most commonly used drug (51 patients), followed by methotrexate (24 patients), azathioprine (23 patients), and cyclophosphamide (15 patients); prednisone, always given as adjunctive treatment, was used in 17 patients." | 1.31 | The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid. ( Ahmed, AR; Baltatzis, S; Foster, CS; Miserocchi, E; Roque, MR, 2002) |
| "A 40-year-old white man with ulcerative colitis, treated with chronic mesalamine and occasional steroids, was admitted to the hospital with a 3-day history of fever, nausea, vomiting, and a rash." | 1.30 | Azathioprine hypersensitivity reaction in a patient with ulcerative colitis. ( Garey, KW; Rainish, MC; Streetman, DS, 1998) |
| " Medical files were reviewed for adverse side effects: fever, pancreatitis, infections, gastrointestinal intolerance, aminotransferase level increase, leukopenia, and thrombocytopenia." | 1.30 | Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. ( Kirschner, BS, 1998) |
| "Thus, differential diagnosis of Goodpasture's syndrome (and probably of any "pulmonary renal syndrome") should include azathioprine hypersensitivity." | 1.29 | Azathioprine hypersensitivity mimicking Goodpasture's syndrome. ( Krapf, R; Schmidl, M; Stetter, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (27.64) | 18.7374 |
| 1990's | 28 (22.76) | 18.2507 |
| 2000's | 25 (20.33) | 29.6817 |
| 2010's | 32 (26.02) | 24.3611 |
| 2020's | 4 (3.25) | 2.80 |
| Authors | Studies |
|---|---|
| Salehi, T | 1 |
| Fleet, AP | 1 |
| Hissaria, P | 1 |
| Carroll, RP | 1 |
| Au Peh, C | 1 |
| Marinaki, AM | 1 |
| Arenas-Hernandez, M | 1 |
| Zarca, K | 2 |
| Chansavang, A | 1 |
| Loriot, MA | 2 |
| Durand-Zaleski, I | 2 |
| Pallet, N | 2 |
| McKenzie, T | 1 |
| Dheda, S | 1 |
| Mantha, M | 1 |
| Larsen, C | 1 |
| Jensen, CH | 1 |
| Fanciullo, J | 1 |
| Sousa, M | 1 |
| Proença, L | 1 |
| Carvalho, J | 1 |
| Terziroli Beretta-Piccoli, B | 1 |
| Mieli-Vergani, G | 1 |
| Vergani, D | 1 |
| Hessels, AC | 1 |
| Sanders, JSF | 1 |
| van de Ven, AAJM | 1 |
| Kroesen, BJ | 1 |
| Lambeck, AJA | 1 |
| Rutgers, A | 1 |
| Stegeman, CA | 1 |
| Chatellier, G | 1 |
| James, A | 1 |
| Blagojevic, J | 1 |
| Benham, SW | 1 |
| Cornall, R | 1 |
| Frater, J | 1 |
| Lennard, L | 1 |
| Chen, D | 1 |
| Lian, F | 1 |
| Yuan, S | 1 |
| Wang, Y | 1 |
| Zhan, Z | 1 |
| Ye, Y | 1 |
| Qiu, Q | 1 |
| Xu, H | 1 |
| Liang, L | 1 |
| Yang, X | 1 |
| García-Martín, P | 1 |
| Sánchez-Pérez, J | 1 |
| Fraga, J | 1 |
| García-Diez, A | 1 |
| Yang, S | 1 |
| McHargue, C | 1 |
| Kessler, C | 1 |
| Tschumi, S | 1 |
| Simonetti, GD | 1 |
| Bianchetti, MG | 1 |
| Kim, HY | 1 |
| Kim, JW | 1 |
| Kim, MJ | 2 |
| Lee, YM | 1 |
| Kang, B | 1 |
| Choe, YH | 2 |
| Lee, SY | 1 |
| Schmutz, JL | 1 |
| Roberts, RL | 2 |
| Barclay, ML | 2 |
| Lee, IH | 1 |
| Kang, GW | 1 |
| Kim, KC | 1 |
| Ardalan, ZS | 1 |
| Vasudevan, A | 1 |
| Testro, AG | 1 |
| Cheraghi, N | 1 |
| Yasuda, M | 1 |
| Deng, A | 1 |
| Mailhot, J | 1 |
| Anthony, D | 1 |
| Diethelm, M | 1 |
| Brändle, M | 1 |
| van Moorsel, SA | 1 |
| Bevers, N | 1 |
| Meurs, M | 1 |
| van Rossum, LK | 1 |
| Hooymans, PM | 1 |
| Wong, DR | 1 |
| Nagy, F | 1 |
| Molnar, T | 1 |
| Szepes, Z | 1 |
| Farkas, K | 1 |
| Nyari, T | 1 |
| Lonovics, J | 1 |
| Karaarslan, IK | 1 |
| Turkmen, M | 1 |
| Ozturk, G | 1 |
| Unal, I | 1 |
| Ertam, I | 1 |
| Kazandi, AC | 1 |
| El-Azhary, RA | 1 |
| Brunner, KL | 1 |
| Gibson, LE | 1 |
| Hindorf, U | 1 |
| Johansson, M | 1 |
| Eriksson, A | 1 |
| Kvifors, E | 1 |
| Almer, SH | 1 |
| Pursnani, A | 1 |
| Yee, H | 1 |
| Slater, W | 1 |
| Sarswat, N | 1 |
| Makhzoumi, Z | 1 |
| DeCapite, T | 1 |
| Gaspari, A | 1 |
| Wahed, M | 1 |
| Louis-Auguste, JR | 1 |
| Baxter, LM | 1 |
| Limdi, JK | 1 |
| McCartney, SA | 1 |
| Lindsay, JO | 1 |
| Bloom, SL | 1 |
| Valdivieso, R | 1 |
| Cevallos, F | 1 |
| Caballero, MT | 1 |
| Quirce, S | 1 |
| Andrejic, J | 1 |
| Rojas-Balcazar, J | 1 |
| Dennis, M | 1 |
| Berkelhammer, C | 1 |
| Korelitz, BI | 1 |
| Reddy, B | 1 |
| Bratcher, J | 1 |
| Lehmann, P | 1 |
| Fleck, M | 1 |
| Schoelmerich, J | 1 |
| Haerle, P | 1 |
| Landy, J | 1 |
| Bhuva, N | 1 |
| Marinaki, A | 1 |
| Mawdsley, J | 1 |
| Mayo, MJ | 1 |
| Bidinger, JJ | 1 |
| Sky, K | 1 |
| Battafarano, DF | 1 |
| Henning, JS | 1 |
| Dewit, O | 1 |
| Moreels, T | 1 |
| Baert, F | 1 |
| Peeters, H | 1 |
| Reenaers, C | 1 |
| de Vos, M | 1 |
| Van Hootegem, P | 1 |
| Muls, V | 1 |
| Veereman, G | 1 |
| Mana, F | 1 |
| Van Outryve, M | 1 |
| Holvoet, J | 1 |
| Naegels, S | 1 |
| Piessevaux, H | 1 |
| Horsmans, Y | 1 |
| Gala, JL | 1 |
| Meggitt, SJ | 1 |
| Anstey, AV | 1 |
| Mohd Mustapa, MF | 1 |
| Reynolds, NJ | 1 |
| Wakelin, S | 1 |
| Jang, KT | 1 |
| Turow, A | 1 |
| Yong, TY | 1 |
| Fok, JS | 1 |
| Li, JY | 1 |
| Hinrichs, R | 1 |
| Schneider, LA | 1 |
| Ozdemir, C | 1 |
| Staib, G | 1 |
| Scharffetter- Kochanek, K | 1 |
| Dubinsky, MC | 1 |
| Feldman, EJ | 1 |
| Abreu, MT | 1 |
| Targan, SR | 1 |
| Vasiliauskas, EA | 1 |
| Mahadevan, U | 1 |
| Mayo, JM | 1 |
| Colmenarejo, MB | 1 |
| Vaquerizo, PJ | 1 |
| Gutierrez, MV | 1 |
| Bajaj, JS | 1 |
| Saeian, K | 1 |
| Varma, RR | 1 |
| Franco, J | 1 |
| Knox, JF | 1 |
| Podoll, J | 1 |
| Emmons, J | 1 |
| Levy, M | 1 |
| Binion, DG | 1 |
| Bir, K | 1 |
| Herzenberg, AM | 1 |
| Carette, S | 1 |
| Karhadkar, AS | 1 |
| Schwartz, HJ | 1 |
| Arora, M | 1 |
| Dutta, SK | 1 |
| Kolho, KL | 1 |
| Ruuska, T | 1 |
| Savilahti, E | 1 |
| Ooi, CY | 1 |
| Bohane, TD | 1 |
| Lee, D | 1 |
| Naidoo, D | 1 |
| Day, AS | 1 |
| de Fonclare, AL | 1 |
| Khosrotehrani, K | 1 |
| Aractingi, S | 1 |
| Duriez, P | 1 |
| Cosnes, J | 1 |
| Beaugerie, L | 1 |
| Lees, CW | 1 |
| Maan, AK | 1 |
| Hansoti, B | 1 |
| Satsangi, J | 1 |
| Arnott, ID | 1 |
| Kirsner, JB | 1 |
| Deutsch, S | 1 |
| Hanauer, SB | 1 |
| Mosbech, H | 1 |
| Andersen, CW | 1 |
| Lawson, DH | 1 |
| Lovatt, GE | 1 |
| Gurton, CS | 1 |
| Hennings, RC | 1 |
| Watts, GF | 1 |
| Corston, R | 1 |
| Riabchinskaia, LA | 1 |
| Lazareva, DN | 1 |
| Wańkowicz, Z | 1 |
| Kałczak, M | 1 |
| Panasiuk, E | 1 |
| Ciszkiewicz, Z | 1 |
| Davis, M | 1 |
| Eddleston, AL | 2 |
| Williams, R | 2 |
| Bommelaer, G | 2 |
| Lapuelle, J | 1 |
| Rumeau, JL | 1 |
| Ribet, A | 1 |
| Pillans, PI | 1 |
| Tooke, AF | 1 |
| Bateman, ED | 1 |
| Ainslie, GM | 1 |
| Stetter, M | 1 |
| Schmidl, M | 1 |
| Krapf, R | 1 |
| Wilson, BE | 1 |
| Parsonnet, J | 1 |
| Paterson, AJ | 1 |
| Lamey, PJ | 1 |
| Lewis, MA | 1 |
| Nolan, A | 1 |
| Rademaker, M | 1 |
| Knowles, SR | 1 |
| Gupta, AK | 1 |
| Shear, NH | 2 |
| Sauder, D | 1 |
| Smak Gregoor, PJ | 1 |
| van Saase, JL | 1 |
| Weimar, W | 1 |
| Kramer, P | 1 |
| Plumb, R | 1 |
| Doolittle, GC | 1 |
| Parnham, AP | 1 |
| Dittmer, I | 1 |
| Mathieson, PW | 1 |
| McIver, A | 1 |
| Dudley, C | 1 |
| Compton, MR | 1 |
| Crosby, DL | 1 |
| Aissaoui, M | 1 |
| Mounedji, N | 1 |
| Mathelier-Fusade, P | 1 |
| Leynadier, F | 1 |
| Dubost, JJ | 1 |
| Abergel, A | 1 |
| Soubrier, M | 1 |
| Sauvezie, B | 1 |
| Tumani, H | 1 |
| George, A | 1 |
| Nau, R | 1 |
| Caramaschi, P | 1 |
| Biasi, D | 1 |
| Carletto, A | 1 |
| Bambara, LM | 1 |
| Knowles, S | 1 |
| Garey, KW | 1 |
| Streetman, DS | 1 |
| Rainish, MC | 1 |
| Fields, CL | 1 |
| Robinson, JW | 1 |
| Roy, TM | 1 |
| Ossorio, MA | 1 |
| Byrd, RP | 1 |
| Marion, JF | 1 |
| Tanis, AA | 1 |
| Kirschner, BS | 1 |
| Romagnuolo, J | 1 |
| Sadowski, DC | 1 |
| Lalor, E | 1 |
| Jewell, L | 1 |
| Thomson, AB | 1 |
| Stratton, JD | 1 |
| Farrington, K | 1 |
| Sanada, I | 1 |
| Kawano, F | 1 |
| Tsukamoto, A | 1 |
| Kiyokawa, T | 1 |
| Lauerma, AI | 1 |
| Koivuluhta, M | 1 |
| Alenius, H | 1 |
| Sofat, N | 1 |
| Houghton, J | 1 |
| McHale, J | 1 |
| Higgens, CS | 1 |
| Craner, MJ | 1 |
| Zajicek, JP | 1 |
| Corbett, M | 1 |
| Schlup, M | 1 |
| Miserocchi, E | 1 |
| Baltatzis, S | 1 |
| Roque, MR | 1 |
| Ahmed, AR | 1 |
| Foster, CS | 1 |
| Haas, J | 1 |
| Patzold, U | 1 |
| Stamm, T | 1 |
| Brandt, LJ | 1 |
| Decker, JL | 1 |
| Klippel, JH | 1 |
| Plotz, PH | 1 |
| Steinberg, AD | 1 |
| Goldenberg, DL | 1 |
| Stor, RA | 1 |
| Doré, P | 1 |
| Meurice, JC | 1 |
| Recart, D | 1 |
| Patte, F | 1 |
| Meys, E | 1 |
| Devogelaer, JP | 1 |
| Geubel, A | 1 |
| Rahier, J | 1 |
| Nagant de Deuxchaisnes, C | 1 |
| Jeurissen, ME | 1 |
| Boerbooms, AM | 1 |
| van de Putte, LB | 1 |
| Kruijsen, MW | 1 |
| Collison, DW | 1 |
| Dahlberg, PJ | 1 |
| Hogan, JD | 1 |
| Vande Walle, JG | 1 |
| Donckerwolcke, RA | 1 |
| Riedel, RR | 1 |
| Schmitt, A | 1 |
| de Jonge, JP | 1 |
| Hartmann, A | 1 |
| Vandepitte, K | 1 |
| Vanrenterghem, Y | 1 |
| Michielsen, P | 1 |
| Saway, PA | 1 |
| Heck, LW | 1 |
| Bonner, JR | 1 |
| Kirklin, JK | 1 |
| Cooper, C | 1 |
| Cotton, DW | 1 |
| Minihane, N | 1 |
| Cawley, MI | 1 |
| Bosch, FH | 1 |
| Meinders, AE | 1 |
| Rhodes, J | 1 |
| Bainton, D | 1 |
| Beck, P | 1 |
| Campbell, H | 1 |
| Wildhirt, E | 1 |
| Burton, JL | 2 |
| Greaves, MW | 2 |
| Marks, J | 1 |
| Dawber, RP | 1 |
| King, JO | 1 |
| Laver, MC | 1 |
| Fairley, KF | 1 |
| Ames, GA | 1 |
| Cooper, MR | 1 |
| Hansen, KS | 1 |
| Maynard, CD | 1 |
| Elrod, IW | 1 |
| Spurr, CL | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| McCullough, DL | 1 |
| Gittes, RF | 1 |
| Lechner, K | 1 |
| Lyons, H | 1 |
| Pinn, VW | 1 |
| Cortell, S | 1 |
| Cohen, JJ | 1 |
| Harrington, JT | 1 |
| Cameron, JS | 1 |
| Lie, TS | 1 |
| Smith, MG | 1 |
| Golding, PL | 1 |
| Mitchell, CG | 1 |
| Kemp, A | 1 |
| Richards, AJ | 1 |
| Swinson, DR | 1 |
| Hamilton, EB | 1 |
| Hillman, HS | 1 |
| Sloth, K | 1 |
| Thomsen, AC | 1 |
| Japa, J | 1 |
| Kardaszewicz, E | 1 |
| Makulu, DR | 1 |
| Wright, P | 1 |
| Barth, P | 1 |
| Kommerell, B | 1 |
| Schiemer, HG | 1 |
| Schimpf, K | 1 |
| Schlierf, G | 1 |
| Wegener, K | 1 |
| Asadov, C | 1 |
| Aliyeva, G | 1 |
| Mustafayeva, K | 1 |
| Grassia, R | 1 |
| Paolo Coppeta, G | 1 |
| Staiano, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenomic Analysis of 6-mercaptopurine in Pediatric Acute Lymphoblastic Leukemia[NCT04770922] | 80 participants (Actual) | Observational | 2021-02-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for azathioprine and Drug Hypersensitivity
| Article | Year |
|---|---|
Reducing risk in thiopurine therapy.
Topics: Azathioprine; Drug Hypersensitivity; Erythrocytes; Female; Genotype; Humans; Male; Mercaptopurine; M | 2020 |
Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments.
Topics: Adult; Age Factors; Azathioprine; Child; Complementary Therapies; Drug Hypersensitivity; Glucocortic | 2017 |
Update on thiopurine pharmacogenetics in inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Drug-Related Side Effects a | 2015 |
Management of autoimmune hepatitis.
Topics: Azathioprine; Budesonide; Drug Hypersensitivity; Hepatitis, Autoimmune; Humans; Immunosuppressive Ag | 2011 |
The cutaneous and systemic manifestations of azathioprine hypersensitivity syndrome.
Topics: Adult; Aged; Azathioprine; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Sch | 2011 |
Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease.
Topics: Antibodies, Monoclonal; Azathioprine; Biotransformation; Crohn Disease; Drug Hypersensitivity; Drug | 2012 |
Adverse effects of azathioprine.
Topics: Alopecia; Azathioprine; Bone Marrow Diseases; Carcinogens; Drug Hypersensitivity; Drug Interactions; | 1984 |
Acute polyarthritis associated with azathioprine for interstitial lung disease.
Topics: Acute Disease; Arthritis; Azathioprine; Drug Hypersensitivity; Drug Therapy, Combination; Female; Hu | 1995 |
Azathioprine hypersensitivity-like reactions--a case report and a review of the literature.
Topics: Adolescent; Azathioprine; Critical Care; Drug Hypersensitivity; Female; Humans; Immunosuppressive Ag | 1995 |
Hypersensitivity reaction to azathioprine.
Topics: Acute Kidney Injury; Adult; Anaphylaxis; Arthritis, Psoriatic; Azathioprine; Diagnosis, Differential | 1998 |
Azathioprine in inflammatory bowel disease, a safe alternative?
Topics: Azathioprine; Bone Marrow; Drug Hypersensitivity; Female; Fertility; Humans; Immunosuppressive Agent | 1998 |
Cholestatic hepatocellular injury with azathioprine: a case report and review of the mechanisms of hepatotoxicity.
Topics: Azathioprine; Cholestasis, Intrahepatic; Crohn Disease; Drug Hypersensitivity; Humans; Immunosuppres | 1998 |
Azathioprine hypersensitivity. Case report and review of the literature.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Graft Rejection; Heart Transplantation; Humans; Male | 1988 |
Acquired inhibitors in nonhemophilic patients.
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Pro | 1974 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath | 1971 |
Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods.
Topics: Animals; Drug Hypersensitivity; Gene Frequency; Genotyping Techniques; Humans; Mercaptopurine; Methy | 2017 |
3 trials available for azathioprine and Drug Hypersensitivity
| Article | Year |
|---|---|
Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months.
Topics: Adolescent; Adult; Amenorrhea; Azathioprine; Child; Clinical Trials as Topic; Complement C3; Cycloph | 1975 |
Controlled trial of azathioprine in Crohn's disease.
Topics: Adolescent; Adult; Aged; Arthritis; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1971 |
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
104 other studies available for azathioprine and Drug Hypersensitivity
| Article | Year |
|---|---|
Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; | 2023 |
Cost-effectiveness analysis of pretreatment screening for NUDT15 defective alleles.
Topics: Asian People; Azathioprine; Bone Marrow Diseases; Cost-Benefit Analysis; Decision Trees; Drug Hypers | 2020 |
Azathioprine hypersensitivity syndrome: report of two cases.
Topics: Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Drug Hypersensitivity S | 2021 |
Point-Counterpoint: TPMT Genotyping for Azathioprine in Adult Medicine.
Topics: Azathioprine; Drug Hypersensitivity; Genotype; Humans; Immunosuppressive Agents; Methyltransferases; | 2017 |
Hypersensitivity to azathioprine in a patient with Crohn's disease: a case report.
Topics: Azathioprine; Crohn Disease; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Middle | 2017 |
Azathioprine Hypersensitivity Syndrome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients.
Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antirheumatic Agents; Azath | 2019 |
Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis.
Topics: Antimetabolites; Azathioprine; Cost-Benefit Analysis; Drug Hypersensitivity; Genetic Testing; Geneti | 2019 |
Azathioprine hypersensitivity presenting as septic shock with encephalopathy.
Topics: Aged; Azathioprine; Brain Diseases; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; S | 2013 |
Implementation of TPMT testing.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Cost-Benefit Analysis; Drug Hypersensitivity; Drug La | 2014 |
Association of thiopurine methyltransferase status with azathioprine side effects in Chinese patients with systemic lupus erythematosus.
Topics: Adult; Alleles; Alopecia; Asian People; Azathioprine; Chemical and Drug Induced Liver Injury; Cohort | 2014 |
Neutrophilic eccrine hidradenitis in a patient with Crohn's disease and azathioprine hypersensitivity syndrome.
Topics: Aged; Azathioprine; Crohn Disease; Drug Hypersensitivity; Hidradenitis; Humans; Immunosuppressive Ag | 2014 |
An asymptomatic papulopustular eruption in an immunosuppressed patient.
Topics: Azathioprine; Drug Eruptions; Drug Hypersensitivity; Female; Hepatitis, Autoimmune; Humans; Immunoco | 2014 |
New-onset bone marrow aplasia in a 15-year-old adolescent with pauci-immune crescentic glomerulonephritis: Questions.
Topics: Adolescent; Azathioprine; Bone Marrow; Drug Hypersensitivity; Glomerulonephritis; Humans; Immunosupp | 2015 |
Safe azathioprine treatment in a pediatric ulcerative colitis patient with TPMT*16 by thiopurine metabolite monitoring.
Topics: Adolescent; Azathioprine; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Methyltransferas | 2014 |
[Neutrophilic eccrine hidradenitis and azathioprine hypersensitivity syndrome].
Topics: Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Hypersensitivity; Hidradenitis; Humans; I | 2014 |
Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Bronchoscopy; Drug Hypersensitivity; Gr | 2016 |
Arthralgia and Fevers in a Patient With Autoimmune Hepatitis.
Topics: Aged; Arthralgia; Azathioprine; Drug Hypersensitivity; Erythema Nodosum; Exanthema; Fever; Hepatitis | 2016 |
Azathioprine hypersensitivity presenting as neutrophilic dermatosis and erythema nodosum.
Topics: Azathioprine; Crohn Disease; Drug Hypersensitivity; Erythema Nodosum; Humans; Immunosuppressive Agen | 2016 |
[Not Available].
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Drug Ther | 2016 |
Azathioprine Therapy in a Pediatric TPMT-Deficient Patient-Still an Option.
Topics: Adolescent; Azathioprine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Monitoring; | 2017 |
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hyperse | 2008 |
A case of drug hypersensitivity due to azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male | 2009 |
Sweet syndrome as a manifestation of azathioprine hypersensitivity.
Topics: Adult; Aged; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immuno | 2008 |
Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease.
Topics: Adult; Azathioprine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Immuno | 2009 |
Hypersensitivity myocarditis associated with azithromycin exposure.
Topics: Anti-Bacterial Agents; Azathioprine; Azithromycin; Drug Hypersensitivity; Drug Therapy, Combination; | 2009 |
Development of Beau's lines in two patients receiving azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Male; Middle Ag | 2009 |
Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Drug Hypersensitivity; Drug Resistance; Fe | 2009 |
Chronic urticaria caused by folic acid.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Drug Hypersensitivity; Female; Folic Acid; Humans | 2009 |
Azathioprine-induced hypersensitivity hepatitis: tolerance to 6-mercaptopurine.
Topics: Acute Disease; Azathioprine; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Drug Hyper | 2010 |
Desensitization of patients with allergic reactions to immunosuppressives in the treatment of inflammatory bowel disease.
Topics: Azathioprine; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Immunosuppressive Agents; | 2010 |
Azathioprine-associated hypersensitivity reaction in a patient with Churg Strauss vasculitis.
Topics: Azathioprine; Churg-Strauss Syndrome; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; | 2010 |
Novel thiopurine methyltransferase variant TPMT*28 results in a misdiagnosis of TPMT deficiency.
Topics: Amino Acid Substitution; Azathioprine; Colitis, Ulcerative; Diagnostic Errors; Drug Hypersensitivity | 2011 |
Limitations of extensive TPMT genotyping in the management of azathioprine-induced myelosuppression in IBD patients.
Topics: Adolescent; Adult; Aged; Azathioprine; DNA Mutational Analysis; Drug Hypersensitivity; Female; Genot | 2011 |
British Association of Dermatologists' guidelines for the safe and effective prescribing of azathioprine 2011.
Topics: Abnormalities, Drug-Induced; Adult; Aged; Azathioprine; Bone Marrow Diseases; Chemical and Drug Indu | 2011 |
Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis.
Topics: Azathioprine; Child; Colitis, Ulcerative; Drug Hypersensitivity; Female; Humans; Immunosuppressive A | 2011 |
Azathioprine hypersensitivity presenting as cardiogenic shock and Sweet's syndrome in a patient with microscopic polyangiitis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Female; Humans; I | 2012 |
Azathioprine hypersensitivity in a patient with peripheral demyelinating polyneuropathy.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Methyltransfera | 2003 |
Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Inflammatory B | 2003 |
6TG: when less is more than you bargained for.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; | 2003 |
Hypersensitivity reaction to azathioprine in a patient with ulcerative colitis. Infrequent manifestations.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Diagnosis, Differential; Drug Hypersensitivity; Fever; Hum | 2004 |
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus | 2005 |
Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis.
Topics: Acute Disease; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Female; Granulomatosis | 2006 |
Severe muscular weakness: an unusual adverse effect of azathioprine therapy.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immunosuppre | 2006 |
Severe adverse reactions to Infliximab therapy are common in young children with inflammatory bowel disease.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Child; Ch | 2007 |
Thiopurine metabolite monitoring in paediatric inflammatory bowel disease.
Topics: Adolescent; Azathioprine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Hype | 2007 |
Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Erythema Nodo | 2007 |
Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease.
Topics: Adult; Age Distribution; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Administration Sched | 2008 |
Selected individual therapeutic problems in inflammatory bowel disease.
Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ | 1984 |
[Azathioprine induced hypersensitivity].
Topics: Adult; Aged; Azathioprine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male | 1982 |
Hypersensitivity to azathioprine in myasthenia gravis.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Mercaptopurine; Middle Aged; Myasthenia Gravis | 1984 |
[Effect of prodigiozan, levamisole and methyluracil on delayed hypersensitivity against a background of immunosuppressor use].
Topics: Animals; Azathioprine; Cyclophosphamide; Drug Hypersensitivity; Drug Interactions; Female; Hypersens | 1983 |
[Acute drug-induced renal failure with severe clinical course].
Topics: Acute Kidney Injury; Adolescent; Anti-Infective Agents; Anticoagulants; Azathioprine; Diuretics; Dru | 1982 |
Hypersensitivity and jaundice due to azathioprine.
Topics: Azathioprine; Cholestasis; Drug Hypersensitivity; Female; Hepatitis; Humans; Middle Aged | 1980 |
[Hypersensitivity reactions and cholestasis. Possible effect of azathioprine].
Topics: Azathioprine; Cholestasis; Drug Hypersensitivity; Female; Humans; Middle Aged | 1980 |
Azathioprine hypersensitivity mimicking Goodpasture's syndrome.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Diagnosis, Differential; Drug Hypers | 1994 |
Azathioprine hypersensitivity mimicking sepsis in a patient with Crohn's disease.
Topics: Aged; Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Hypersensitivity; Fever; Humans; In | 1993 |
Pemphigus vulgaris precipitated by glibenclamide therapy.
Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole | 1993 |
Fever and rigors as sole symptoms of azathioprine hypersensitivity.
Topics: Azathioprine; Drug Hypersensitivity; Fever; Humans; Immunosuppressive Agents; Kidney Transplantation | 1995 |
Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Thera | 1996 |
Acute allergic reactions associated with azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nephritis, Interstitia | 1996 |
Rhabdomyolysis associated with azathioprine hypersensitivity syndrome.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; Rhabdomyolysis | 1996 |
[Pancreatitis caused by azathioprine: immuno-allergy?].
Topics: Acute Disease; Adult; Azathioprine; Crohn Disease; Drug Hypersensitivity; Humans; Male; Pancreatitis | 1996 |
[Acute cytolytic hepatitis in azathioprine hypersensitivity].
Topics: Acute Disease; Adult; Antirheumatic Agents; Azathioprine; Behcet Syndrome; Chemical and Drug Induced | 1996 |
[Myasthenic crisis caused by azathioprine-induced fever].
Topics: Aged; Azathioprine; Critical Care; Drug Hypersensitivity; Drug Therapy, Combination; Fever; Humans; | 1997 |
Azathioprine hypersensitivity in a patient affected by systemic lupus erythematosus.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Lupus Erythema | 1997 |
Azathioprine hypersensitivity reactions: caution upon rechallenge.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Retreatment | 1997 |
Azathioprine hypersensitivity reaction in a patient with ulcerative colitis.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Immunosuppressive Agents; M | 1998 |
Toxicity of 6-mercaptopurine/azathioprine in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Child; Colorectal Neoplasms; Drug Hypersensitivity; Fe | 1998 |
Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Databases as Topic; Drug Hypersensitivity; | 1998 |
Relapse of vasculitis, sepsis, or azathioprine allergy?
Topics: Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Male; Re | 1998 |
[Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine].
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Hepatitis, Autoimmune; Humans; Immunosuppressive | 2000 |
Recalcitrant allergic contact dermatitis from azathioprine tablets.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Dermatitis, Allergic Contact; Drug Hypersensitivity; | 2001 |
Azathioprine hypersensitivity.
Topics: Adult; Antirheumatic Agents; Azathioprine; Drug Hypersensitivity; Drug Therapy, Combination; Female; | 2001 |
Immunosuppressive treatments in MS--side effects from azathioprine.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Multiple Sclerosis; Nausea; P | 2001 |
Azathioprine hypersensitivity mimicking underlying inflammatory bowel disease.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; Drug Hypersensitiv | 2001 |
The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Azathi | 2002 |
[Intrahepatic cholestasis, an allergic reaction in azathioprine therapy?].
Topics: Adult; Azathioprine; Cholestasis; Drug Hypersensitivity; Humans; Male; Multiple Sclerosis | 1978 |
Formication and azathioprine therapy.
Topics: Ants; Azathioprine; Drug Hypersensitivity; Female; Humans; Middle Aged; Nervous System Diseases; Sen | 1977 |
Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis.
Topics: Acute Disease; Azathioprine; Dermatomyositis; Diagnosis, Differential; Drug Hypersensitivity; Female | 1975 |
[Reaction of hypersensitivity to azathioprine].
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1992 |
Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity.
Topics: Acute Disease; Arthritis, Rheumatoid; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; | 1992 |
Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Eruptions; D | 1990 |
Azathioprine hypersensitivity in bullous pemphigoid.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Fever; Headache; Humans; Pemphigoid, Bullous; Ski | 1990 |
Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy.
Topics: Azathioprine; Child; Creatinine; Drug Hypersensitivity; Female; Fever; Humans; Kidney Transplantatio | 1990 |
Gastrointestinal type 1 hypersensitivity to azathioprine.
Topics: Azathioprine; Drug Hypersensitivity; Edema; Eosinophilia; Gastroenteritis; Humans; Intestinal Mucosa | 1990 |
Azathioprine hypersensitivity in a renal transplant recipient.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Fever; Humans; Kidney Transplantation; Male | 1990 |
Azathioprine hypersensitivity manifesting as acute focal hepatocellular necrosis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; | 1986 |
[General malaise, high fever and arthralgia as a rare side effect of azathioprine].
Topics: Azathioprine; Drug Hypersensitivity; Fever; Glomerulonephritis; Humans; Joint Diseases; Male; Middle | 1985 |
[Penicillamine therapy of chronic liver diseases].
Topics: Azathioprine; Chronic Disease; Drug Hypersensitivity; Female; Glucocorticoids; Hepatitis; Humans; Li | 1974 |
Azathioprine in pemphigus vulgaris.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Male; | 1970 |
Sensitivity to azathioprine.
Topics: Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Female; Glomerulonephritis; Graft Reje | 1972 |
Platelet survival and sequestration patterns in thrombocytopenic disorders.
Topics: Adult; Aged; Azathioprine; Blood Platelets; Cell Survival; Chloramphenicol; Chromium Isotopes; Dexam | 1972 |
Successful renal transplantation after forty-five hours of extracorporeal perfusion.
Topics: Acute Kidney Injury; Azathioprine; Biopsy; Cadaver; Cold Temperature; Drug Hypersensitivity; Graft R | 1973 |
Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.
Topics: Acute Kidney Injury; Adult; Azathioprine; Chlorothiazide; Drug Hypersensitivity; Eosinophils; Female | 1973 |
Azathioprine for pemphigus and pemphigoid--a 4 year follow-up.
Topics: Adult; Aged; Anemia; Azathioprine; Bone Neoplasms; Drug Evaluation; Drug Hypersensitivity; Female; F | 1974 |
[Immunosuppressive therapy in experimental and clinical liver transplantation].
Topics: Anaphylaxis; Animals; Anti-Bacterial Agents; Antilymphocyte Serum; Azathioprine; Depression, Chemica | 1970 |
Cell-mediated immune responses in chronic liver diseases.
Topics: Acidosis, Renal Tubular; Antigens; Autoimmune Diseases; Azathioprine; Cell Migration Inhibition; Chr | 1972 |
Azathioprine in connective tissue disorders.
Topics: Anemia; Arthritis, Rheumatoid; Azathioprine; Drug Hypersensitivity; Gold; Humans; Male; Middle Aged | 1972 |
Intestinal malabsorption with subtotal villous atrophy unresponsive to a gluten-free diet but responding to immunosuppressive therapy.
Topics: Adult; Atrophy; Azathioprine; Biopsy; Diet Therapy; Drug Hypersensitivity; Glutens; Humans; Intestin | 1972 |
Acute renal insufficiency during treatment with azathioprine.
Topics: Acute Kidney Injury; Administration, Oral; Azathioprine; Biopsy; Drug Hypersensitivity; Glomerular F | 1971 |
[Results of immunosuppressive treatment of visceral lupus erythematosus].
Topics: Adolescent; Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agen | 1969 |
Immune response to insulin in guinea pigs.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Azathioprine; Body Weight; Cattle; Chromatograp | 1971 |
[Purpura fulminans in the pathological anatomical picture of a case of thrombophlebitis migrans et saltans].
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Heparin; Humans; Prednisone; Purpura; Thrombophl | 1968 |
Severe muscular weakness as an isolated symptom of azathioprine hypersensitivity.
Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Mercaptopurine; | 2011 |