azathioprine has been researched along with Diseases of Immune System in 16 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is characterized by high interindividual differences in bioavailability and metabolization." | 1.31 | Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. ( Decaux, G; Desager, JP; Horsmans, Y; Prospert, F, 2000) |
| "Prednisone was administered to 134 patients (90 per cent) in whom a peak platelet count occurred at a median of eight days, at which time four distinct patterns of response became evident: 20 patients (15 per cent) achieved complete remission with platelet counts greater than 200 X 10(9)/I, and of these 13 relapsed; 46 (34 per cent) had incomplete remission with platelet counts between 100 and 200 X 10(9)/I, and of these 38 relapsed; 22 (17 per cent) had a partial remission with platelet counts between 50 and 100 X 10(9)/I, and 14 have relapsed; the remaining 46 (34 per cent) failed to respond to prednisone." | 1.27 | Results of treatment in immune thrombocytopenia. ( Dent, DM; Jacobs, P; Wood, L, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katz, P | 1 |
| Niaudet, P | 1 |
| Cohen, JA | 1 |
| Raps, EC | 1 |
| Pallis, M | 1 |
| Lim, KL | 1 |
| Gardner-Medwin, JM | 1 |
| Robins, RA | 1 |
| Powell, RJ | 1 |
| Miller, E | 1 |
| Decaux, G | 1 |
| Prospert, F | 1 |
| Horsmans, Y | 1 |
| Desager, JP | 1 |
| Oshrain, HI | 1 |
| Mender, S | 1 |
| Mandel, ID | 1 |
| Baenkler, VH | 1 |
| Bach, JF | 1 |
| Hallauer, W | 1 |
| Schirmeister, J | 1 |
| Keller, P | 1 |
| Krieger, G | 1 |
| Schirrmeister, H | 1 |
| Tilson, HH | 1 |
| Beale, KM | 1 |
| Jacobs, P | 1 |
| Wood, L | 1 |
| Dent, DM | 1 |
| Van Scoik, KG | 1 |
| Johnson, CA | 1 |
| Porter, WR | 1 |
| Kaufman, DB | 1 |
| McIntosh, RM | 1 |
| Videbaek, A | 1 |
4 reviews available for azathioprine and Diseases of Immune System
| Article | Year |
|---|---|
Critical neurologic illness in the immunocompromised patient.
Topics: Acquired Immunodeficiency Syndrome; Anti-Inflammatory Agents; Antibody Formation; Azathioprine; Brai | 1995 |
The use of cytotoxic agents in the treatment of immune-mediated diseases of dogs and cats.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azathioprine; Cat Disea | 1997 |
The pharmacology and metabolism of the thiopurine drugs 6-mercaptopurine and azathioprine.
Topics: Animals; Azathioprine; Biotransformation; DNA; DNA Replication; Humans; Immune System Diseases; Merc | 1985 |
[Immunosuppressive therapy. A survey concerning rationale, risks, indications and contraindications].
Topics: Adolescent; Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Immune System Diseases; | 1973 |
1 trial available for azathioprine and Diseases of Immune System
| Article | Year |
|---|---|
Correlation between CD29 density on CD8+ lymphocytes and serum IgG in systemic lupus erythematosus.
Topics: Antigens, CD; Azathioprine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; | 1997 |
11 other studies available for azathioprine and Diseases of Immune System
| Article | Year |
|---|---|
Therapy for immunologic disease. New ways of using old drugs.
Topics: Adrenal Cortex Hormones; Azathioprine; Cyclophosphamide; Cytotoxicity, Immunologic; Drug Administrat | 1983 |
[Immunosuppressive agents].
Topics: Alkylating Agents; Antilymphocyte Serum; Azathioprine; Humans; Immune System Diseases; Immunosuppres | 1980 |
Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine.
Topics: Adult; Azathioprine; Biological Availability; Churg-Strauss Syndrome; Erythrocyte Indices; Erythrocy | 2000 |
Periodontal status of patients with reduced immunocapacity.
Topics: Adult; Azathioprine; Dental Plaque; Gingivitis; Humans; Immune System Diseases; Immunosuppressive Ag | 1979 |
[Immunologic diseases--conclusion 10. Immunosuppression, recommendations for ambulatory treatment and supervision].
Topics: Ambulatory Care; Azathioprine; Cyclophosphamide; Female; Humans; Immune System Diseases; Immunosuppr | 1977 |
The mode of action of immunosuppressive agents.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cell Survi | 1975 |
[Collagen disease with pure red cell anemia and perimembraneous glomerulonephritis (author's transl)].
Topics: Adult; Anemia; Anemia, Hemolytic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Bone Marrow Ce | 1976 |
Pharmacoepidemiology: the industry's perspective.
Topics: Arthritis, Rheumatoid; Azathioprine; Decision Making; Drug Industry; Epidemiology; Humans; Immune Sy | 1988 |
Azathioprine for treatment of immune-mediated diseases of dogs and cats.
Topics: Animals; Azathioprine; Cat Diseases; Cats; Dog Diseases; Dogs; Immune System Diseases | 1988 |
Results of treatment in immune thrombocytopenia.
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclophosphamide; Female; Humans; Immune System Diseases; Mal | 1986 |
The effects of azathioprine on experimentally induced immune complex renal disease in rabbits.
Topics: Animals; Azathioprine; Blood Protein Electrophoresis; Cattle; Creatinine; Fluorescent Antibody Techn | 1972 |