Page last updated: 2024-10-23

azathioprine and Diathesis

azathioprine has been researched along with Diathesis in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]."7.69Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996)
" Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug."3.73Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005)
"The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]."3.69Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996)
"Severe side effects, specially infections, are uncommon but clinically relevant with several deaths reported."2.43Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review. ( García-López, S; Gomollón-García, F; Pérez-Gisbert, J, 2005)
"Two patients presented cutaneous varicella complicated by pneumonia and esophagitis respectively, one patient had cutaneous herpes zoster and the other had fatal pneumonia possibly caused by the Herpesvirus."1.32[Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy]. ( Bernal, I; Cabré, E; Domènech, E; García-Planella, E; Gassull, MA, 2003)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's3 (20.00)18.2507
2000's7 (46.67)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Vuille-Lessard, É1
Montani, M1
Bosch, J1
Semmo, N1
Chaparro, M1
Gisbert, JP1
Cordero Ruiz, P1
Castro Márquez, C1
Méndez Rufián, V1
Castro Laria, L1
Caunedo Álvarez, A1
Romero Vázquez, J1
Herrerías Gutiérrez, JM1
Bernal, I1
Domènech, E1
García-Planella, E1
Cabré, E1
Gassull, MA1
Nogal-Ruiz, JJ1
Gómez-Barrio, A1
Escario, JA1
Martínez-Fernández, AR1
Canet, S1
Garrigue, V1
Bismuth, J1
Chong, G1
Lesnik, A1
Taourel, P1
Mourad, G1
Hokari, A1
Zeniya, M1
Bajaj, JS1
Saeian, K1
Varma, RR1
Franco, J1
Knox, JF1
Podoll, J1
Emmons, J1
Levy, M1
Binion, DG1
García-López, S1
Gomollón-García, F1
Pérez-Gisbert, J1
Cuchural, GJ1
Levey, AS1
Pauker, SG1
De Lord, C1
Marsh, JC1
Smith, JG1
Singer, CR1
Gordon-Smith, EC1
Margiotta, V1
Pizzo, I1
Pizzo, G1
Barbaro, A1
Czaja, AJ1
Eguchi, K1
Trachtman, H1
Hammerschlag, MR1
Tejani, A1
Steinberg, S1
Gershon, AA1

Reviews

5 reviews available for azathioprine and Diathesis

ArticleYear
[Role of thiopurine agents in ulcerative colitis].
    Gastroenterologia y hepatologia, 2011, Volume: 34 Suppl 3

    Topics: Azathioprine; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Disease Susceptibility;

2011
[Nocardiosis--is it frequently observed after the introduction of new immunosuppressive agents in renal transplantation?].
    Nephrologie, 2004, Volume: 25, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Com

2004
[Difference between autoimmune hepatitis (AIH) with and without hepatitis C virus (HCV)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 7, Issue:Pt 1

    Topics: Adrenal Cortex Hormones; Antiviral Agents; Autoantibodies; Azathioprine; Disease Susceptibility; Dru

2004
Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review.
    Gastroenterologia y hepatologia, 2005, Volume: 28, Issue:10

    Topics: Administration, Oral; Adrenal Cortex Hormones; Azathioprine; Clinical Trials as Topic; Colitis, Ulce

2005
Drug therapy in the management of type 1 autoimmune hepatitis.
    Drugs, 1999, Volume: 57, Issue:1

    Topics: Azathioprine; Disease Susceptibility; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis,

1999

Trials

1 trial available for azathioprine and Diathesis

ArticleYear
Efficacy of adalimumab in patients with Crohn's disease and failure to infliximab therapy: a clinical series.
    Revista espanola de enfermedades digestivas, 2011, Volume: 103, Issue:6

    Topics: Abdominal Abscess; Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclo

2011

Other Studies

9 other studies available for azathioprine and Diathesis

ArticleYear
Autoimmune hepatitis triggered by SARS-CoV-2 vaccination.
    Journal of autoimmunity, 2021, Volume: 123

    Topics: 2019-nCoV Vaccine mRNA-1273; Aged; Autoantibodies; Azathioprine; Carcinoma, Transitional Cell; Causa

2021
[Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Acyclovir; Adult; Aged; Antiviral Agents; Azathioprine; Chickenpox; Crohn Disease; Disease Susceptib

2003
Effect of Anapsos in a murine model of experimental trichomoniasis.
    Parasite (Paris, France), 2003, Volume: 10, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Azathioprine; Cyclophosphamide; Disease Models, Animal; Disease Sus

2003
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:5

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus

2005
Kidney failure or cancer. Should immunosuppression be continued in a transplant patient with malignant melanoma?
    Medical decision making : an international journal of the Society for Medical Decision Making, 1984, Volume: 4, Issue:1

    Topics: Adult; Azathioprine; Disease Susceptibility; Female; Glomerulonephritis; Graft Rejection; Humans; Im

1984
Fatal autoimmune pancytopenia following bone marrow transplantation for aplastic anaemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Aspergillosis; Autoantibodies; Autoimmune Di

1996
Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1996, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Azathioprine; Calcium Channel Blockers; Child; Cyclosporine; Dental Calculus; Den

1996
Systemic lupus erythematosus complicated by cytomegalovirus-induced hemophagocytic syndrome and colitis.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:2

    Topics: Autoimmune Diseases; Azathioprine; Colitis; Cyclophosphamide; Cytokines; Cytomegalovirus Infections;

2002
A longitudinal study of varicella immunity in pediatric renal transplant recipients.
    The Journal of infectious diseases, 1986, Volume: 154, Issue:2

    Topics: Adolescent; Adult; Antibodies, Viral; Azathioprine; Chickenpox; Child; Child, Preschool; Cyclosporin

1986