azathioprine has been researched along with Diathesis in 15 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Excerpt | Relevance | Reference |
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"The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]." | 7.69 | Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996) |
" Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug." | 3.73 | Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005) |
"The factors associated with cyclosporin A (CsA)- and nifedipine (Nif)-induced gingival overgrowth were investigated in 113 renal transplant recipients receiving CsA alone (Group 1) [n = 61], CsA and Nif (Group 2) [n = 28], or azathioprine (Aza) (Control Group) [n = 24]." | 3.69 | Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens. ( Barbaro, A; Margiotta, V; Pizzo, G; Pizzo, I, 1996) |
"Severe side effects, specially infections, are uncommon but clinically relevant with several deaths reported." | 2.43 | Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review. ( García-López, S; Gomollón-García, F; Pérez-Gisbert, J, 2005) |
"Two patients presented cutaneous varicella complicated by pneumonia and esophagitis respectively, one patient had cutaneous herpes zoster and the other had fatal pneumonia possibly caused by the Herpesvirus." | 1.32 | [Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy]. ( Bernal, I; Cabré, E; Domènech, E; García-Planella, E; Gassull, MA, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (13.33) | 18.7374 |
1990's | 3 (20.00) | 18.2507 |
2000's | 7 (46.67) | 29.6817 |
2010's | 2 (13.33) | 24.3611 |
2020's | 1 (6.67) | 2.80 |
Authors | Studies |
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Vuille-Lessard, É | 1 |
Montani, M | 1 |
Bosch, J | 1 |
Semmo, N | 1 |
Chaparro, M | 1 |
Gisbert, JP | 1 |
Cordero Ruiz, P | 1 |
Castro Márquez, C | 1 |
Méndez Rufián, V | 1 |
Castro Laria, L | 1 |
Caunedo Álvarez, A | 1 |
Romero Vázquez, J | 1 |
Herrerías Gutiérrez, JM | 1 |
Bernal, I | 1 |
Domènech, E | 1 |
García-Planella, E | 1 |
Cabré, E | 1 |
Gassull, MA | 1 |
Nogal-Ruiz, JJ | 1 |
Gómez-Barrio, A | 1 |
Escario, JA | 1 |
Martínez-Fernández, AR | 1 |
Canet, S | 1 |
Garrigue, V | 1 |
Bismuth, J | 1 |
Chong, G | 1 |
Lesnik, A | 1 |
Taourel, P | 1 |
Mourad, G | 1 |
Hokari, A | 1 |
Zeniya, M | 1 |
Bajaj, JS | 1 |
Saeian, K | 1 |
Varma, RR | 1 |
Franco, J | 1 |
Knox, JF | 1 |
Podoll, J | 1 |
Emmons, J | 1 |
Levy, M | 1 |
Binion, DG | 1 |
García-López, S | 1 |
Gomollón-García, F | 1 |
Pérez-Gisbert, J | 1 |
Cuchural, GJ | 1 |
Levey, AS | 1 |
Pauker, SG | 1 |
De Lord, C | 1 |
Marsh, JC | 1 |
Smith, JG | 1 |
Singer, CR | 1 |
Gordon-Smith, EC | 1 |
Margiotta, V | 1 |
Pizzo, I | 1 |
Pizzo, G | 1 |
Barbaro, A | 1 |
Czaja, AJ | 1 |
Eguchi, K | 1 |
Trachtman, H | 1 |
Hammerschlag, MR | 1 |
Tejani, A | 1 |
Steinberg, S | 1 |
Gershon, AA | 1 |
5 reviews available for azathioprine and Diathesis
Article | Year |
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[Role of thiopurine agents in ulcerative colitis].
Topics: Azathioprine; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Disease Susceptibility; | 2011 |
[Nocardiosis--is it frequently observed after the introduction of new immunosuppressive agents in renal transplantation?].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Com | 2004 |
[Difference between autoimmune hepatitis (AIH) with and without hepatitis C virus (HCV)].
Topics: Adrenal Cortex Hormones; Antiviral Agents; Autoantibodies; Azathioprine; Disease Susceptibility; Dru | 2004 |
Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review.
Topics: Administration, Oral; Adrenal Cortex Hormones; Azathioprine; Clinical Trials as Topic; Colitis, Ulce | 2005 |
Drug therapy in the management of type 1 autoimmune hepatitis.
Topics: Azathioprine; Disease Susceptibility; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis, | 1999 |
1 trial available for azathioprine and Diathesis
Article | Year |
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Efficacy of adalimumab in patients with Crohn's disease and failure to infliximab therapy: a clinical series.
Topics: Abdominal Abscess; Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclo | 2011 |
9 other studies available for azathioprine and Diathesis
Article | Year |
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Autoimmune hepatitis triggered by SARS-CoV-2 vaccination.
Topics: 2019-nCoV Vaccine mRNA-1273; Aged; Autoantibodies; Azathioprine; Carcinoma, Transitional Cell; Causa | 2021 |
[Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy].
Topics: Acyclovir; Adult; Aged; Antiviral Agents; Azathioprine; Chickenpox; Crohn Disease; Disease Susceptib | 2003 |
Effect of Anapsos in a murine model of experimental trichomoniasis.
Topics: Adjuvants, Immunologic; Animals; Azathioprine; Cyclophosphamide; Disease Models, Animal; Disease Sus | 2003 |
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus | 2005 |
Kidney failure or cancer. Should immunosuppression be continued in a transplant patient with malignant melanoma?
Topics: Adult; Azathioprine; Disease Susceptibility; Female; Glomerulonephritis; Graft Rejection; Humans; Im | 1984 |
Fatal autoimmune pancytopenia following bone marrow transplantation for aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Aspergillosis; Autoantibodies; Autoimmune Di | 1996 |
Cyclosporin- and nifedipine-induced gingival overgrowth in renal transplant patients: correlations with periodontal and pharmacological parameters, and HLA-antigens.
Topics: Adolescent; Adult; Azathioprine; Calcium Channel Blockers; Child; Cyclosporine; Dental Calculus; Den | 1996 |
Systemic lupus erythematosus complicated by cytomegalovirus-induced hemophagocytic syndrome and colitis.
Topics: Autoimmune Diseases; Azathioprine; Colitis; Cyclophosphamide; Cytokines; Cytomegalovirus Infections; | 2002 |
A longitudinal study of varicella immunity in pediatric renal transplant recipients.
Topics: Adolescent; Adult; Antibodies, Viral; Azathioprine; Chickenpox; Child; Child, Preschool; Cyclosporin | 1986 |