azathioprine has been researched along with Diabetic Nephropathies in 51 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In summary, mycophenolate mofetil is superior to azathioprine in maintaining remission and preventing relapse in lupus nephritis." | 3.78 | [Nephrology]. ( Martin, PY; Saudan, P, 2012) |
| " We describe a patient suffering from pancytopenia following a combination therapy of azathioprine and allopurinol because of lupus erythematodes and diabetic nephropathy with hyperuricemia." | 3.72 | [Panzytopenia from combination therapy with azathioprin and allopurinol]. ( Seidel, W, 2004) |
| " In the CsA group, 71% required either a significant reduction in CsA dosage with the addition of azathioprine or a complete switch to azathioprine, mainly because of CsA-associated nephrotoxicity." | 2.66 | A randomized trial comparing cyclosporine with antilymphoblast-globulin-azathioprine for renal allograft recipients. Results at 2 1/2-6 years. ( Ascher, NL; Canafax, DM; Flick, B; Fryd, DS; Johnson, CP; Najarian, JS; Payne, WD; Simmons, RL; Sutherland, DE, 1988) |
| "Delayed graft function was observed in 34." | 1.38 | Outcome of deceased donor renal transplantation in diabetic nephropathy: a single-center experience from a developing country. ( Engineer, DP; Godara, SM; Gumber, MR; Jain, SH; Kute, VB; Modi, PR; Munjappa, BC; Patel, HV; Sainaresh, VV; Shah, PR; Shah, VR; Trivedi, HL; Vanikar, AV, 2012) |
| "In juvenile diabetics with diabetic nephropathy transplantation of the pancreas at the time of renal transplantation is thought to improve the progression of diabetic complications." | 1.26 | [Transplantation of pancreas and kidney in diabetic nephropathy (author's transl)]. ( Baumgartner, D; Binswanger, U; Largiadèr, F; Uhlschmid, G, 1982) |
| "The requirement for insulin decreased in both patients during the period of renal insufficiency and increased following transplantation; this seemed to be related to the large dose of steroids given because now that a maintenance level of steroids has been established, both patients require the same dosage of insulin as they did before the onset of renal insufficiency." | 1.25 | Treatment of renal failure from diabetic nephropathy with cadaveric homograft. ( Beaudry, C; Laplate, L, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (47.06) | 18.7374 |
| 1990's | 19 (37.25) | 18.2507 |
| 2000's | 5 (9.80) | 29.6817 |
| 2010's | 3 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Opelz, G | 1 |
| Döhler, B | 1 |
| Kute, VB | 1 |
| Godara, SM | 1 |
| Shah, PR | 1 |
| Jain, SH | 1 |
| Engineer, DP | 1 |
| Patel, HV | 1 |
| Gumber, MR | 1 |
| Munjappa, BC | 1 |
| Sainaresh, VV | 1 |
| Vanikar, AV | 1 |
| Modi, PR | 1 |
| Shah, VR | 1 |
| Trivedi, HL | 1 |
| Saudan, P | 1 |
| Martin, PY | 1 |
| Woeste, G | 1 |
| Wullstein, C | 1 |
| Dette, K | 1 |
| Pridöhl, O | 1 |
| Lübke, P | 1 |
| Bechstein, WO | 1 |
| Pannu, HS | 1 |
| Singh, D | 1 |
| Sandhu, JS | 1 |
| Yang, L | 1 |
| Liu, YF | 1 |
| Liu, SR | 1 |
| Liang, J | 1 |
| Cui, H | 1 |
| Meng, YM | 1 |
| Wu, G | 1 |
| Li, GC | 1 |
| Seidel, W | 1 |
| Sutherland, DE | 9 |
| Goetz, FC | 3 |
| Elick, BA | 1 |
| Najarian, JS | 7 |
| Peter, S | 1 |
| Keusch, G | 1 |
| Binswanger, U | 2 |
| Wilczek, H | 2 |
| Gunnarsson, R | 3 |
| Lundgren, G | 3 |
| Ost, L | 2 |
| Fryd, DS | 5 |
| Strand, M | 1 |
| Ascher, N | 2 |
| Simmons, RL | 5 |
| Vanrenterghem, Y | 1 |
| Waer, M | 1 |
| Ang, K | 1 |
| van der Schueren, E | 1 |
| Gruwez, J | 1 |
| Bouillon, R | 1 |
| Michielsen, P | 1 |
| Klintmalm, G | 1 |
| Tydén, G | 2 |
| Ostman, J | 2 |
| Groth, CG | 2 |
| Strom, TB | 2 |
| Largiadèr, F | 2 |
| Baumgartner, D | 1 |
| Uhlschmid, G | 1 |
| Boonstra, JG | 1 |
| Bruijn, JA | 1 |
| Hermans, J | 1 |
| Lemkes, HH | 1 |
| Ringers, J | 1 |
| van der Pijl, H | 1 |
| van der Woude, FJ | 1 |
| Troppmann, C | 1 |
| Benedetti, E | 1 |
| Gruessner, AC | 1 |
| Papalois, BE | 1 |
| Gruessner, RW | 1 |
| Brennan, DC | 1 |
| Scharp, DW | 1 |
| White, NH | 1 |
| Flavin, KS | 1 |
| Zukosky, JM | 1 |
| Ansara, MF | 1 |
| Cryer, PE | 1 |
| Lacy, PE | 1 |
| Schroeder, TJ | 1 |
| Hariharan, S | 1 |
| First, MR | 1 |
| Brayman, KL | 1 |
| Egidi, MF | 1 |
| Naji, A | 1 |
| Friedman, AL | 1 |
| Holland, MT | 1 |
| Tomaszewski, JE | 1 |
| Samini, F | 1 |
| Perloff, J | 1 |
| Grossman, R | 1 |
| Barker, CF | 1 |
| Osei, K | 1 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Cantarovich, D | 4 |
| Hourmant, M | 4 |
| Dantal, J | 4 |
| Giral, M | 1 |
| Paineau, J | 3 |
| Karam, G | 2 |
| Soulillou, JP | 4 |
| Baatard, R | 2 |
| Le Mauff, B | 1 |
| Jacques, Y | 1 |
| Murat, A | 2 |
| Shapiro, ME | 1 |
| Abrams, JM | 1 |
| Brown, RS | 1 |
| Steinman, TI | 1 |
| Pruijt, JF | 1 |
| Haanen, JB | 1 |
| Hollander, AA | 1 |
| den Ottolander, GJ | 1 |
| Isenberg, A | 1 |
| Singh, TP | 1 |
| Shen, GK | 1 |
| Freed, BM | 1 |
| Conti, DJ | 1 |
| Giral-Classe, M | 1 |
| Blancho, G | 1 |
| Le Normand, L | 1 |
| Bitker, MO | 1 |
| Barrou, B | 1 |
| Mouquet, C | 1 |
| Benalia, H | 1 |
| Ourahma, S | 1 |
| Grimaldi, A | 1 |
| Richard, F | 1 |
| Chatelain, C | 1 |
| Hinduja, A | 1 |
| Abraham, G | 1 |
| Eapen, G | 1 |
| Shroff, S | 1 |
| Rao, R | 1 |
| Kuruvilla, S | 1 |
| Fonseca, JA | 1 |
| Ianhez, LE | 1 |
| Sabbaga, E | 1 |
| Arap, S | 1 |
| Brazy, PC | 1 |
| Pirsch, JD | 1 |
| Belzer, FO | 1 |
| Hopt, UT | 1 |
| Büsing, M | 1 |
| Schareck, W | 1 |
| Pfeffer, F | 1 |
| Irkin, I | 1 |
| Becker, HD | 1 |
| Wegener, S | 1 |
| Auner, M | 1 |
| Templin, R | 1 |
| Schmitt, E | 1 |
| Erdmann, T | 1 |
| Fünfhausen, G | 1 |
| Squifflet, JP | 1 |
| Florack, G | 1 |
| Alexandre, GP | 1 |
| Pescovitz, MD | 2 |
| Gruber, SA | 2 |
| Ascher, NL | 3 |
| Kruse, LV | 1 |
| Payne, WD | 4 |
| Brunkwall, J | 1 |
| Bergqvist, D | 1 |
| Bergentz, SE | 1 |
| Bornmyr, S | 1 |
| Husberg, B | 1 |
| Brattström, C | 1 |
| Johnson, CP | 1 |
| Canafax, DM | 1 |
| Flick, B | 1 |
| Land, W | 1 |
| Castro, LA | 1 |
| White, DJ | 1 |
| Hillebrand, G | 1 |
| Hammer, C | 1 |
| Klare, B | 1 |
| Fornara, P | 1 |
| Elick, B | 1 |
| Fryd, D | 1 |
| Bewick, M | 1 |
| Rudge, CJ | 1 |
| Miller, BH | 1 |
| Monkhouse, PM | 1 |
| Reid, KE | 1 |
| Verbi, V | 1 |
| Bach, MC | 1 |
| Adler, JL | 1 |
| Breman, J | 1 |
| P'eng, FK | 1 |
| Sahyoun, A | 1 |
| Schlesinger, RM | 1 |
| Madras, P | 1 |
| Monaco, AP | 1 |
| Cerilli, J | 1 |
| Evans, WE | 1 |
| Sotos, JF | 1 |
| Beaudry, C | 1 |
| Laplate, L | 1 |
| Kampf, D | 1 |
| Baethke, R | 1 |
| Idezuki, Y | 1 |
| Merkel, FK | 1 |
| Kelly, WD | 1 |
| Lillehei, RC | 1 |
| Zosin, C | 1 |
| Mănescu, N | 1 |
| Iacob, G | 1 |
| Schwarzkopf, A | 1 |
| Sabo, I | 1 |
| Gluhovschi, G | 1 |
4 reviews available for azathioprine and Diabetic Nephropathies
| Article | Year |
|---|---|
Azathioprine-induced pure red-cell aplasia.
Topics: Azathioprine; Diabetic Nephropathies; Female; Humans; Kidney Transplantation; Middle Aged; Red-Cell | 1996 |
Ciclosporin in renal transplantation.
Topics: Adolescent; Age Factors; Aged; Azathioprine; Child; Child, Preschool; Cyclosporins; Diabetic Nephrop | 1986 |
Renal transplantation in diabetes.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Child; Costs and Cost Analysis; Diabetes Mellitus; Dia | 1986 |
[Therapy of glomerulonephritis with corticosteroids and immunosuppressive agents].
Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Azathioprine; Child; Cyclophosphamide; Diabetic Nephrop | 1974 |
8 trials available for azathioprine and Diabetic Nephropathies
| Article | Year |
|---|---|
[Treatment of chronic kidney failure in diabetes mellitus].
Topics: Adult; Azathioprine; Cardiovascular Diseases; Cerebrovascular Disorders; Diabetic Nephropathies; Dia | 1983 |
Modification of methodology results in improvement in simultaneous kidney-islet success.
Topics: Antilymphocyte Serum; Azathioprine; C-Peptide; Cells, Cultured; Cyclosporine; Diabetes Mellitus, Typ | 1995 |
Anti-interleukin 2 monoclonal antibody following simultaneous pancreatic and kidney transplantation: a randomized trial vs rabbit antithymocyte globulin.
Topics: Actuarial Analysis; Adult; Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Azathioprine; Cycl | 1993 |
Randomized comparison of triple therapy and antithymocyte globulin induction treatment after simultaneous pancreas-kidney transplantation.
Topics: Adrenal Cortex Hormones; Adult; Animals; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes | 1998 |
Renal transplantation in diabetic patients: a survey of 100 cases.
Topics: Adult; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ne | 1992 |
Frequency of diabetes-related complications in renal allograft recipients prospectively randomized to cyclosporine or azathioprine.
Topics: Azathioprine; Cyclosporins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Follow-Up Studies; Hu | 1987 |
A randomized trial comparing cyclosporine with antilymphoblast-globulin-azathioprine for renal allograft recipients. Results at 2 1/2-6 years.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Creatinine; Cyclosp | 1988 |
Thromboembolic complications in renal allograft recipients. A report from the prospective randomized study of cyclosporine versus azathioprine-antilymphocyte globulin.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Diabe | 1987 |
39 other studies available for azathioprine and Diabetic Nephropathies
| Article | Year |
|---|---|
Association of mismatches for HLA-DR with incidence of posttransplant hip fracture in kidney transplant recipients.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Cyclosporine; Diabetic Nephropathies; Female; Graft Re | 2011 |
Outcome of deceased donor renal transplantation in diabetic nephropathy: a single-center experience from a developing country.
Topics: Adult; Aged; Antilymphocyte Serum; Azathioprine; Cadaver; Calcineurin Inhibitors; Creatinine; Delaye | 2012 |
[Nephrology].
Topics: Anticholesteremic Agents; Azathioprine; Azetidines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Ty | 2012 |
Tacrolimus/mycophenolate mofetil vs cyclosporine A/Azathioprine after simultaneous pancreas and kidney transplantation: five-year results of a randomized study.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Diab | 2002 |
Lipid profile before and after renal transplantation--a longitudinal study.
Topics: Adult; Azathioprine; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cyclosporine | 2003 |
[Analysis of rejection after simultaneous pancreas-kidney transplantation].
Topics: Administration, Oral; Adult; Azathioprine; Cyclosporine; Diabetic Nephropathies; Drug Therapy, Combi | 2004 |
[Panzytopenia from combination therapy with azathioprin and allopurinol].
Topics: Aged; Allopurinol; Antirheumatic Agents; Autoantibodies; Azathioprine; Blood Cell Count; Diabetes Me | 2004 |
Experience with 49 segmental pancreas transplants in 45 diabetic patients: results according to technique, donor source and immunosuppression.
Topics: Azathioprine; Cyclosporins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Immunosuppres | 1983 |
Improved results of renal transplantation in diabetic nephropathy.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Blood Transfusion; Cyclosporins; Diabetic Nephropathies; | 1984 |
Results of renal transplantation in diabetics at the University of Minnesota since 1979, including a comparison of outcome in diabetic and nondiabetic recipients randomized to cyclosporine versus azathioprine for immunosuppression.
Topics: Antilymphocyte Serum; Azathioprine; Cyclosporins; Diabetic Nephropathies; Graft Survival; Humans; Im | 1984 |
Cadaveric kidney transplantation in diabetics after total lymphoid irradiation (TLI).
Topics: Adult; Azathioprine; Blood Transfusion; Cadaver; Diabetic Nephropathies; Follow-Up Studies; Graft Re | 1984 |
Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporins; Diabetic Nephropathies; Humans; Immunosuppression | 1984 |
Immunosuppressive agents in renal transplantation.
Topics: Adult; Animals; Azathioprine; Cyclosporins; Diabetic Nephropathies; Graft Enhancement, Immunologic; | 1984 |
[Transplantation of pancreas and kidney in diabetic nephropathy (author's transl)].
Topics: Adult; Azathioprine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Humans; Kidney Trans | 1982 |
The incidence of interstitial and vascular kidney rejection after pancreas-kidney transplantation.
Topics: Adult; Azathioprine; Case-Control Studies; Cyclosporine; Diabetic Nephropathies; Female; Graft Rejec | 1995 |
Early endocrine pancreas graft function and outcome after simultaneous pancreas-kidney transplantation.
Topics: Adult; Age Factors; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Dia | 1995 |
Variations in bioavailability of cyclosporine and relationship to clinical outcome in renal transplant subpopulations.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Azathioprine; Biological Ava | 1995 |
Is induction therapy necessary for successful simultaneous pancreas and kidney transplantation in the cyclosporine era?
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephrop | 1994 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
OKT3 first-line treatment of acute rejection episodes following combined pancreas and kidney transplantation.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephrop | 1994 |
Successful pancreas-renal transplantation without anti-T-cell antibody induction.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetic Nephropathies; Female; Graft Survi | 1995 |
[Long-term results in pancreas transplantation in diabetes in the pre-cyclosporin era].
Topics: Adult; Antilymphocyte Serum; Azathioprine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female | 1996 |
Selective CellCept therapy in high-risk renal transplant recipients.
Topics: Adult; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Drug Therapy, | 1998 |
[Combined renal and pancreas transplantation as treatment for chronic renal insufficiency of diabetic origin: a series of 50 consecutive transplantations].
Topics: Adult; Azathioprine; Combined Modality Therapy; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Ne | 1999 |
An early experience with Simulect (basiliximab): an IL-2 receptor antibody.
Topics: Antibodies, Monoclonal; Azathioprine; Basiliximab; Cyclosporine; Diabetic Nephropathies; Drug Therap | 2000 |
Factors affecting renal allograft function in long-term recipients.
Topics: Adolescent; Adult; Azathioprine; Cadaver; Diabetic Nephropathies; Female; Graft Survival; Humans; Hy | 1992 |
Importance of cyclosporine dosage and blood levels in simultaneous pancreas and kidney transplant success.
Topics: Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, | 1992 |
Is HLA matching worthwhile in pancreatic transplantation?
Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1992 |
[Factors influencing the result of kidney transplantation with special reference to the HLA system in conventional immunosuppression].
Topics: Azathioprine; Blood Transfusion; Diabetic Nephropathies; Follow-Up Studies; Graft Survival; Histocom | 1990 |
Current status of clinical pancreas transplantation.
Topics: Azathioprine; Cyclosporins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Graft Survival; Human | 1986 |
Deep venous thrombosis in patients undergoing renal transplantation--effects of cyclosporine A.
Topics: Azathioprine; Cyclosporins; Diabetic Nephropathies; Humans; Kidney Transplantation; Thrombophlebitis | 1987 |
Metabolic control at two months to 4.5 years after pancreatic transplantation, with special reference to the role of cyclosporine.
Topics: Antilymphocyte Serum; Azathioprine; Blood Glucose; Cyclosporins; Diabetes Mellitus, Type 1; Diabetic | 1987 |
Kidney transplantation in diabetic patients.
Topics: Azathioprine; Cyclosporins; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Evaluation Studies as | 1987 |
The use of pressimmune in renal transplantation: a four-year study.
Topics: Adult; Animals; Antilymphocyte Serum; Azathioprine; Diabetic Nephropathies; Female; Graft Survival; | 1985 |
Influence of rejection therapy on fungal and nocardial infections in renal-transplant recipients.
Topics: Adult; Antilymphocyte Serum; Aspergillosis; Aspergillus fumigatus; Azathioprine; Child, Preschool; C | 1973 |
Renal transplantation in infants and children.
Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Child; Child, Preschool; Cystinosis; Diabetic Nephro | 1972 |
Treatment of renal failure from diabetic nephropathy with cadaveric homograft.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cadaver; Creatinine; Diabetes Mellitus, Type 1; Diabetic | 1973 |
Experiences with pancreaticoduodenal allotransplantation.
Topics: Adult; Animals; Antilymphocyte Serum; Azathioprine; Blood Glucose; Diabetes Mellitus, Type 1; Diabet | 1968 |
[Immunodepressive therapy in nephropathies].
Topics: Azathioprine; Chlorambucil; Collagen Diseases; Diabetic Nephropathies; Glomerulonephritis; Humans; I | 1969 |