azathioprine has been researched along with Di Guglielmo Disease in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine has been associated with chromosome abnormalities." | 1.26 | Erythroleukemia in a renal transplant recipient. ( Baker, MA; deVeber, GA; Ellerton, JA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, TS | 1 |
| Cheong, JW | 1 |
| Song, J | 1 |
| Lee, KA | 1 |
| Lee, SG | 1 |
| Kim, J | 1 |
| Yoon, S | 1 |
| Choi, JR | 1 |
| Park, R | 1 |
| Hoy, WE | 1 |
| Packman, CH | 1 |
| Freeman, RB | 1 |
| Ellerton, JA | 1 |
| deVeber, GA | 1 |
| Baker, MA | 1 |
1 review available for azathioprine and Di Guglielmo Disease
| Article | Year |
|---|---|
Acute erythroleukemia with der(1;7)(q10;p10) as a sole acquired abnormality after treatment with azathioprine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Bone Marrow; Chromosomes, Human, Pair | 2008 |
2 other studies available for azathioprine and Di Guglielmo Disease
| Article | Year |
|---|---|
Evolution of acute leukemia in a renal transplant patient--? Relationship to azathioprine.
Topics: Adult; Azathioprine; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Leukemia, Ery | 1982 |
Erythroleukemia in a renal transplant recipient.
Topics: Azathioprine; Chromosome Aberrations; Humans; Kidney Transplantation; Leukemia, Erythroblastic, Acut | 1979 |