azathioprine has been researched along with Dental Plaque in 9 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe gingival hyperplasia (GH) is one of the most frequent side-effects associated with the prescription of Cyclosporine-A (CsA)." | 3.71 | Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients. ( Baboolal, K; Newcombe, RG; Subramanian, N; Thomas, DW, 2001) |
| " Papillary bleeding index, time since transplant and azathioprine dosage were significant in the univariate and multivariate models (adjusted R=43." | 1.35 | Gingival overgrowth in renal transplant subjects medicated with tacrolimus in the absence of calcium channel blockers. ( Cezário, ES; Costa, FO; Cota, LO; Ferreira, SD; Siqueira, FM; Soares, RV; Zenóbio, EG, 2008) |
| " Duration of treatment, dosage of drugs per kg body weight and serum cyclosporin levels were recorded." | 1.30 | Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy. ( Ashley, FP; Koffman, CG; Morel, A; Ogg, CS; Rigden, SP; Smith, D; Wilson, RF, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pistorius, A | 1 |
| Willershausen, B | 1 |
| Callaway, A | 1 |
| Cezário, ES | 1 |
| Cota, LO | 1 |
| Ferreira, SD | 1 |
| Siqueira, FM | 1 |
| Soares, RV | 1 |
| Zenóbio, EG | 1 |
| Costa, FO | 1 |
| Been, V | 1 |
| Engel, D | 1 |
| Wondimu, B | 1 |
| Dahllöf, G | 1 |
| Berg, U | 1 |
| Modéer, T | 1 |
| Wilson, RF | 1 |
| Morel, A | 1 |
| Smith, D | 1 |
| Koffman, CG | 1 |
| Ogg, CS | 1 |
| Rigden, SP | 1 |
| Ashley, FP | 1 |
| Thomas, DW | 1 |
| Baboolal, K | 1 |
| Subramanian, N | 1 |
| Newcombe, RG | 1 |
| Kardachi, BJ | 1 |
| Newcomb, GM | 1 |
| Oshrain, HI | 1 |
| Mender, S | 1 |
| Mandel, ID | 1 |
| Schuller, PD | 1 |
| Freedman, HL | 1 |
| Lewis, DW | 1 |
9 other studies available for azathioprine and Dental Plaque
| Article | Year |
|---|---|
Effects of selected immunouppressive drugs on prostaglandin release, protein synthesis and cell proliferation in human gingival fibroblasts and on the growth of plaque bacteria.
Topics: Actinomyces viscosus; Aggregatibacter actinomycetemcomitans; Azathioprine; Capnocytophaga; Cell Divi | 2003 |
Gingival overgrowth in renal transplant subjects medicated with tacrolimus in the absence of calcium channel blockers.
Topics: Adult; Aged; Azathioprine; Calcium Channel Blockers; Chi-Square Distribution; Dental Plaque; Female; | 2008 |
The effects of immunosuppressive drugs on periodontal inflammation in human renal allograft patients.
Topics: Adult; Azathioprine; Dental Plaque; Humans; Immunosuppressive Agents; Kidney Transplantation; Longit | 1982 |
Cyclosporin-A-induced gingival overgrowth in renal transplant children.
Topics: Administration, Oral; Adolescent; Azathioprine; Child; Child, Preschool; Cyclosporine; Dental Plaque | 1993 |
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Azathioprine; Body We | 1998 |
Cyclosporin A-induced gingival overgrowth is unrelated to allograft function in renal transplant recipients.
Topics: Adolescent; Adult; Aged; Azathioprine; Calcium Channel Blockers; Child; Child, Preschool; Creatinine | 2001 |
A clinical study of gingival inflammation in renal transplant recipients taking immunosuppressive drugs.
Topics: Adolescent; Adult; Aged; Azathioprine; Dental Plaque; Female; Gingivitis; Humans; Immunosuppressive | 1978 |
Periodontal status of patients with reduced immunocapacity.
Topics: Adult; Azathioprine; Dental Plaque; Gingivitis; Humans; Immune System Diseases; Immunosuppressive Ag | 1979 |
Periodontal status of renal transplant patients receiving immunosuppressive therapy.
Topics: Adult; Age Factors; Azathioprine; Dental Calculus; Dental Plaque; Female; Humans; Immunosuppressive | 1973 |