azathioprine has been researched along with Delayed Hypersensitivity in 48 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of pre- and post-challenge treatments with trifluoperazine and palmitoylcarnitine, two protein kinase C (PKC) inhibitors characterised by their interaction with the phospholipid enzyme cofactor, on the inflammation caused by delayed hypersensitivity (DTH) to dinitrofluorobenzene (DNFB) and sheep red blood cells (SRBC) in mice is reported." | 7.70 | On the activity of trifluoperazine and palmitoylcarnitine in mice: delayed hypersensitivity models. ( Giner, RM; Góngora, L; Máñez, S; Recio, MC; Ríos, JL, 2000) |
| " The immunomodulating capabilities of the agents tested are assessed by their effects on the allergic contact reaction to oxazolone, a cell-mediated delayed hypersensitivity reaction." | 4.77 | The effect of selected immunomodulating agents on experimental contact reactions. ( Anderson, C, 1985) |
| "The effect of pre- and post-challenge treatments with trifluoperazine and palmitoylcarnitine, two protein kinase C (PKC) inhibitors characterised by their interaction with the phospholipid enzyme cofactor, on the inflammation caused by delayed hypersensitivity (DTH) to dinitrofluorobenzene (DNFB) and sheep red blood cells (SRBC) in mice is reported." | 3.70 | On the activity of trifluoperazine and palmitoylcarnitine in mice: delayed hypersensitivity models. ( Giner, RM; Góngora, L; Máñez, S; Recio, MC; Ríos, JL, 2000) |
| "The effect of experimental long-term azathioprine administration on pre-existing in vitro and in vivo manifestations of delayed hypersensitivity was examined." | 3.65 | Lack of effect of azathioprine on phytohemagglutinin-induced lymphocyte transformation and established delayed cutaneous hypersensitivity. ( Ainsworth, SK; Fitts, CT; Sharbaugh, RJ, 1976) |
| " Using appropriate dosage schedules, cyclophosphamide, methotrexate and procarbazine either potentiated or had no effect on DTH." | 1.26 | Selective effects of immunosuppressive agents against the delayed hypersensitivity response and humoral response to sheep red blood cells in mice. ( Doherty, NS, 1981) |
| "Increased Arthus reactions occurred after early and late multiple doses of HC and after a late single dose of CY at the highest dose." | 1.26 | Effect of hydrocortisone, cyclophosphamide, azathioprine and methotrexate on cutaneous delayed and arthus hypersensitivity in the rat. ( Mansour, A; Nelson, DS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (4.17) | 29.6817 |
| 2010's | 2 (4.17) | 24.3611 |
| 2020's | 2 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Akhtar, MF | 1 |
| Nisa, MU | 1 |
| Saleem, A | 1 |
| Hamid, I | 1 |
| Alsharif, KF | 1 |
| Abdel-Daim, MM | 1 |
| Rahman, MH | 1 |
| Shah, M | 1 |
| Sohail, K | 1 |
| Javaid, Z | 1 |
| Møllehave, LA | 3 |
| Nelveg-Kristensen, KE | 3 |
| van Besouw, NM | 1 |
| van der Mast, BJ | 1 |
| van de Wetering, J | 1 |
| Rischen-Vos, J | 1 |
| Weimar, W | 1 |
| de Oliveira, RG | 1 |
| Aarestrup, FM | 2 |
| Miranda, C | 1 |
| Vieira, BJ | 1 |
| Ferreira, AP | 2 |
| Andrade, LC | 2 |
| Oliveira, RG | 1 |
| Côrtes, AJ | 1 |
| Aarestrup, BJ | 1 |
| BICKS, RO | 1 |
| BROWN, G | 1 |
| HICKEY, HD | 1 |
| ROSENBERG, EW | 1 |
| EPSTEIN, WL | 2 |
| MAIBACH, HI | 2 |
| O'Grady, F | 1 |
| Pennington, JH | 1 |
| Stansfield, AG | 1 |
| Blyth, WA | 1 |
| Harbour, DA | 1 |
| Hill, TJ | 1 |
| Riabchinskaia, LA | 1 |
| Lazareva, DN | 1 |
| Doherty, NS | 1 |
| Góngora, L | 1 |
| Máñez, S | 1 |
| Giner, RM | 1 |
| Recio, MC | 1 |
| Ríos, JL | 1 |
| Mansour, A | 1 |
| Nelson, DS | 1 |
| van der Kwast, TH | 1 |
| Olthof, JG | 1 |
| de Ruiter, H | 1 |
| Benner, R | 1 |
| James, DG | 1 |
| Sharbaugh, RJ | 1 |
| Ainsworth, SK | 1 |
| Fitts, CT | 1 |
| van der Heyden, AA | 1 |
| Bloemena, E | 1 |
| Out, TA | 1 |
| Wilmink, JM | 1 |
| Schellekens, PT | 1 |
| van Oers, MH | 1 |
| Keown, PA | 1 |
| Stiller, CR | 1 |
| Kimmelstiel, FM | 1 |
| Waltzer, WC | 1 |
| Rapaport, FT | 1 |
| Anderson, C | 1 |
| Zapata-Sirvent, RL | 1 |
| Narrod, JA | 1 |
| Hansbrough, JF | 1 |
| Shillitoe, EJ | 1 |
| Lehner, T | 1 |
| Lessof, MH | 1 |
| Harrison, DF | 1 |
| Swanson, MA | 1 |
| Schwartz, RS | 1 |
| Cruchaud, A | 1 |
| Pometta, D | 1 |
| Rousso, C | 1 |
| Budtz-Jörgensen, E | 1 |
| Müllerova, M | 1 |
| Pekárek, J | 1 |
| Nouza, K | 1 |
| Svejcar, J | 1 |
| Trnka, L | 1 |
| Matousek, V | 1 |
| Sengar, DP | 1 |
| Rashid, A | 1 |
| Harris, JE | 1 |
| Moore, G | 1 |
| Harley, JP | 1 |
| Otero, R | 1 |
| Turk, JL | 1 |
| Parker, D | 1 |
| House, AK | 1 |
| Boak, JL | 1 |
| Hulme, B | 1 |
| Braun, WE | 1 |
| Straffon, RA | 1 |
| Nakamoto, S | 1 |
| Popowniak, KL | 1 |
| Gifford, RW | 1 |
| Kuruvila, C | 1 |
| Zachary, AA | 1 |
| Zweiman, B | 2 |
| Klein, M | 1 |
| Binder, HJ | 1 |
| Mitchell, M | 1 |
| Aaronson, R | 1 |
| Spiro, H | 1 |
| Alexander, JL | 1 |
| Hall, TC | 1 |
| Diethelm, AG | 1 |
| Murray, JE | 1 |
| Mackay, IR | 1 |
| D'Amico, RA | 1 |
| Castroviejo, R | 1 |
| Arinoviche, R | 1 |
| Loewi, G | 1 |
| Joseph, WL | 2 |
| Melewicz, F | 2 |
| Morton, DL | 2 |
| Alexander, JW | 1 |
| McCoy, HV | 1 |
| Phair, JP | 1 |
| Altemeier, WA | 1 |
| Silberberg, DH | 1 |
| Currey, HL | 1 |
| Rowland, LP | 1 |
| Brown, CH | 1 |
| Turner-Warwick, M | 1 |
| Corder, MP | 1 |
| Young, RC | 1 |
| DeVita, VT | 1 |
| Steiner, B | 1 |
3 reviews available for azathioprine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Defence systems of the body, immunosuppression and immunotherapy.
Topics: Alkylating Agents; Antibody Formation; Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; B-Ly | 1976 |
Control of rejection of transplanted organs.
Topics: Adaptation, Physiological; Animals; Antilymphocyte Serum; Azathioprine; Cyclosporins; Drug Therapy, | 1986 |
The effect of selected immunomodulating agents on experimental contact reactions.
Topics: Animals; Azathioprine; Basophils; Cell Division; Croton Oil; Cyclophosphamide; Cyclosporins; Dermati | 1985 |
1 trial available for azathioprine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Treatment of Crohn's disease with azathioprine: a controlled evaluation.
Topics: Administration, Oral; Adolescent; Adult; Antibody Formation; Antigens; Azathioprine; Clinical Trials | 1974 |
44 other studies available for azathioprine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Contemporary uses of old folks: the immunomodulatory and toxic potential of fenbufen.
Topics: Animals; Azathioprine; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunity, Humoral; Mic | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Humans; Hypersensitivity, Delayed; Male; Middle Aged; S | 2022 |
Tapering immunosuppressive therapy significantly improves in vivo cutaneous delayed type hypersensitivity responses.
Topics: Antigens, Bacterial; Azathioprine; Female; Follow-Up Studies; Humans; Hypersensitivity, Delayed; Imm | 2008 |
Low-level laser therapy reduces delayed hypersensitivity reaction to ovalbumin in Balb/C mice.
Topics: Animals; Azathioprine; Hypersensitivity, Delayed; Immunomodulation; Immunosuppressive Agents; Low-Le | 2010 |
Low-level laser reduces the production of TNF-α, IFN-γ, and IL-10 induced by OVA.
Topics: Animals; Azathioprine; Hypersensitivity, Delayed; Immunosuppression Therapy; Immunosuppressive Agent | 2013 |
FURTHER OBSERVATIONS ON A DELAYED HYPERSENSITIVITY REACTION IN THE GUINEA PIG COLON.
Topics: Allergens; Allergy and Immunology; Animals; Azathioprine; Colon; Guinea Pigs; Hypersensitivity; Hype | 1965 |
IMMUNOLOGIC COMPETENCE OF PATIENTS WITH PSORIASIS RECEIVING CYTOTOXIC DRUG THERAPY.
Topics: Allergens; Allergy and Immunology; Aniline Compounds; Antibody Formation; Antigen-Antibody Reactions | 1965 |
IMMUNOLOGIC RESPONSES OF HEALTHY VOLUNTEERS RECEIVING AZATHIOPRINE (IMURAN).
Topics: Aniline Compounds; Antimetabolites; Azathioprine; Biomedical Research; Dermatitis, Contact; Drug The | 1965 |
Delayed hypersensitivity in mouse-thigh candidosis.
Topics: Animals; Azathioprine; Candidiasis; Hypersensitivity, Delayed; Mice | 1967 |
Effect of immunosuppression on recurrent herpes simplex in mice.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Erythema; Female; Herpes Simplex; Hypersensitivity, Del | 1980 |
[Effect of prodigiozan, levamisole and methyluracil on delayed hypersensitivity against a background of immunosuppressor use].
Topics: Animals; Azathioprine; Cyclophosphamide; Drug Hypersensitivity; Drug Interactions; Female; Hypersens | 1983 |
Selective effects of immunosuppressive agents against the delayed hypersensitivity response and humoral response to sheep red blood cells in mice.
Topics: Animals; Antibody Formation; Azathioprine; Cyclophosphamide; Erythrocytes; Hypersensitivity, Delayed | 1981 |
On the activity of trifluoperazine and palmitoylcarnitine in mice: delayed hypersensitivity models.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Dexamethasone; Dinitrofluorobenzene; Enzyme Inhibit | 2000 |
Effect of hydrocortisone, cyclophosphamide, azathioprine and methotrexate on cutaneous delayed and arthus hypersensitivity in the rat.
Topics: Animals; Arthus Reaction; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Female; | 1979 |
Secondary delayed type hypersensitivity to sheep red blood cells in mice: dependence on long-lived memory cells.
Topics: Animals; Antigens; Azathioprine; Erythrocytes; Female; Hypersensitivity, Delayed; Immunization, Pass | 1979 |
Lack of effect of azathioprine on phytohemagglutinin-induced lymphocyte transformation and established delayed cutaneous hypersensitivity.
Topics: Animals; Azathioprine; Female; Hypersensitivity, Delayed; Immunity, Cellular; Lectins; Lymphocyte Ac | 1976 |
The influence of immunosuppressive treatment on immune responsiveness in vivo in kidney transplant recipients.
Topics: Antibody Formation; Azathioprine; Cyclosporins; Humans; Hypersensitivity, Delayed; Immunity, Cellula | 1989 |
Skin hypersensitivity of the delayed type in renal transplant patients receiving azathioprine or cyclosporine.
Topics: Azathioprine; Cyclosporins; Dinitrochlorobenzene; Diphtheria Toxoid; Diphtheria-Tetanus Vaccine; Dru | 1987 |
Restoration of delayed hypersensitivity in mice receiving immunosuppressive drugs by cimetidine.
Topics: Animals; Azathioprine; Cimetidine; Female; Hypersensitivity, Delayed; Immunity, Cellular; Immunosupp | 1985 |
Immunological features of Wegener's granulomatosis.
Topics: Adult; Aged; Autoantibodies; Autoimmune Diseases; Azathioprine; Blood Proteins; Cell Migration Inhib | 1974 |
Immunosuppressive therapy. The relation between clinical response and immunologic competence.
Topics: Adolescent; Adult; Anemia, Hemolytic, Autoimmune; Antibody Formation; Azathioprine; Chronic Disease; | 1967 |
Treatment of systemic lupus erythematosus (SLE) with immunosuppressive drugs 1: An analysis of immunologic data.
Topics: Adult; Aged; Antibodies, Antinuclear; Antibody Formation; Autoantibodies; Autoimmune Diseases; Azath | 1967 |
Immune response to C. albicans in monkeys with experimental candidiasis in the palate.
Topics: Agglutination Tests; Animals; Azathioprine; Biopsy; Candida albicans; Candidiasis, Oral; Cell Migrat | 1973 |
Immunosuppression and experimental tuberculosis. II. The effects of immunosuppressive agents and antilymphocyte serum on the organ dissemination of mycobacteria and on the development of specific delayed hypersensitivity.
Topics: Animals; Antigens, Bacterial; Antilymphocyte Serum; Azathioprine; Azauridine; Cell Migration Inhibit | 1974 |
In vitro cellular immunity and in vivo delayed hypersensitivity in uremic patients maintained on hemodialysis.
Topics: Azathioprine; Female; Glomerulonephritis; Graft Rejection; Humans; Hypersensitivity, Delayed; Immuni | 1974 |
Immunosuppressive activity of azathioprine in experimental infection of the mouse with Trichinella spiralis (Nematoda).
Topics: Azathioprine; Hypersensitivity, Delayed; Immunity, Cellular; Trichinellosis | 1974 |
Further studies on B-lymphocyte suppression in delayed hypersensitivity, indicating a possible mechanism for Jones-Mote hypersensitivity.
Topics: Animals; Antibodies; Antineoplastic Agents; Azathioprine; B-Lymphocytes; Cyclophosphamide; Fluorine; | 1973 |
An in vitro study of renal allograft recipients for cellular delayed type hypersensitivity to glomerular basement membrane and disrupted spleen cells.
Topics: Adult; Azathioprine; Basement Membrane; Cell Migration Inhibition; Child; Cyclophosphamide; Female; | 1972 |
Mismatched HL-A haplotypes with antigens HL-A1, 3, and 11 associated with excellent renal allograft function.
Topics: Antibodies; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Antilymphocyte Serum; Azathioprine; | 1973 |
Immunosuppressive effects of specific classes of agents with special reference to organ transplantation. Immunosuppression by thiopurines.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Antibody Formation; Azathioprine; Com | 1973 |
The effects of cytosine arabinoside on canine renal allografts.
Topics: Animals; Azathioprine; Cytarabine; Dogs; Hematopoiesis; Hypersensitivity, Delayed; Immunosuppressive | 1969 |
Autoimmune disease.
Topics: Adolescent; Antibodies, Antinuclear; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases | 1969 |
Suppression of the immune response in keratoplasy.
Topics: Animals; Azathioprine; Cornea; Corneal Transplantation; Hypersensitivity, Delayed; Immunosuppressive | 1969 |
Comparison of the effects of two cytotoxic drugs and of antilymphocytic serum on immune and non-immune inflammation in experimental animals.
Topics: Animals; Antilymphocyte Serum; Arthritis; Azathioprine; Cyclophosphamide; DNA Replication; Exudates | 1970 |
Immunosuppressive drugs. I.
Topics: Adrenal Cortex Hormones; Animals; Antibodies; Antibody Formation; Antilymphocyte Serum; Antineoplast | 1970 |
Delayed cutaneous hypersensitivity to dinitrochlorobenzene as a method of quantitating immunosuppressive therapy for organ transplantation.
Topics: Animals; Azathioprine; Dogs; Hypersensitivity, Delayed; Immunosuppressive Agents; Skin Tests; Skin T | 1971 |
Non-specific and adaptive immunity in renal transplantation.
Topics: Animals; Antibody Formation; Antigens; Antilymphocyte Serum; Azathioprine; Dogs; Ear, Inner; Female; | 1969 |
In vitro lymphocyte responsiveness of human subjects receiving azathioprine.
Topics: Antigens; Azathioprine; Blood Cell Count; Candida; Culture Techniques; Humans; Hypersensitivity, Del | 1971 |
A comparison of immunosuppressive and anti-inflammatory agents in the rat.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Antilymphocyte Serum; Arthritis; Azathioprine | 1971 |
Immunosuppressive drugs in treatment of myasthenia gravis.
Topics: Adult; Autoimmune Diseases; Azathioprine; Blood Cell Count; Busulfan; Cyclophosphamide; Female; Huma | 1971 |
The treatment of cryptogenic fibrosing alveolitis with immunosuppressant drugs.
Topics: Adult; Agglutination Tests; Antibodies, Antinuclear; Azathioprine; Chlorambucil; Complement Fixation | 1971 |
Spontaneous development of mammary adenocarcinoma following prolonged immunosuppression in the dog.
Topics: Adenocarcinoma; Animals; Azathioprine; Chlorine; Dogs; Female; Hypersensitivity, Delayed; Mammary Ne | 1970 |
Delayed hypersensitivity in patients with cancer.
Topics: Azathioprine; Croton Oil; Hodgkin Disease; Humans; Hypersensitivity, Delayed; Immunosuppressive Agen | 1971 |
[The treatment of pulmonary hemorrhage in 3 immunoallergic patients with Azathioprine].
Topics: Adolescent; Autoimmune Diseases; Azathioprine; Child; Child, Preschool; Hemoptysis; Humans; Hypersen | 1968 |