azathioprine has been researched along with Cystic Fibrosis in 6 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "MODE OF ACTION OF URSODEOXYCHOLIC ACID: In cholestasis, the impaired biliary secretion of toxic bile acids causes their accumulation in the liver and a subsequent hepatic failure." | 4.81 | [Treatment of cholestatic liver diseases]. ( Gatzen, M; Pausch, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Cassan, C | 1 |
| Cinotti, E | 1 |
| Savarino, E | 1 |
| Vo, HD | 1 |
| Xu, J | 1 |
| Rabinowitz, SS | 1 |
| Fisher, SE | 1 |
| Schwarz, SM | 1 |
| Bugano, DD | 1 |
| Campos, SV | 1 |
| Afonso, JE | 1 |
| Caramori, ML | 1 |
| Teixeira, RH | 1 |
| Carraro, RM | 1 |
| Strabelli, TM | 1 |
| Machado, CM | 1 |
| Samano, MN | 1 |
| Pêgo-Fernandes, P | 1 |
| Jatene, FB | 1 |
| Tan, HL | 1 |
| Shah, N | 1 |
| Suri, R | 1 |
| Girault, D | 1 |
| Haloun, A | 1 |
| Viard, L | 1 |
| Bellon, G | 1 |
| Gottrand, F | 1 |
| Guillemain, R | 1 |
| Lenoir, G | 1 |
| Ladurie, FL | 1 |
| Plouvier, E | 1 |
| Storni, V | 1 |
| Gatzen, M | 1 |
| Pausch, J | 1 |
2 reviews available for azathioprine and Cystic Fibrosis
| Article | Year |
|---|---|
The liver in pediatric gastrointestinal disease.
Topics: Adolescent; Antibodies, Monoclonal; Azathioprine; Celiac Disease; Chemical and Drug Induced Liver In | 2014 |
[Treatment of cholestatic liver diseases].
Topics: Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bile; Child; Cholagogues and Choleretics | 2002 |
1 trial available for azathioprine and Cystic Fibrosis
| Article | Year |
|---|---|
Sandimmun neoral improves the bioavailability of cyclosporin A and decreases inter-individual variations in patients affected with cystic fibrosis.
Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Biological Availability; Child; Cyclosporine; | 1995 |
3 other studies available for azathioprine and Cystic Fibrosis
| Article | Year |
|---|---|
An unusual cutaneous manifestation in a patient with cystic fibrosis.
Topics: Anti-Inflammatory Agents; Azathioprine; Biopsy; Budesonide; Colonoscopy; Crohn Disease; Cystic Fibro | 2014 |
Impact of cytomegalovirus infection in lung transplant patients under universal prophylaxis: single-center experience in Brazil.
Topics: Adult; Antibodies, Monoclonal; Azathioprine; Basiliximab; Brazil; Bronchiectasis; Cohort Studies; Cy | 2010 |
Azathioprine in the management of enteropathy in cystic fibrosis.
Topics: Adolescent; Azathioprine; Cystic Fibrosis; Gastrointestinal Diseases; Humans; Male | 2011 |