Page last updated: 2024-10-23

azathioprine and Cushing's Syndrome

azathioprine has been researched along with Cushing's Syndrome in 13 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
" These studies provide a compelling case for a re-evaluation of the long-term use of glucocorticoids in SLE, focusing on minimizing glucocorticoid exposure as part of the strategy to improve long-term outcomes."2.55It hasn't gone away: the problem of glucocorticoid use in lupus remains. ( Apostolopoulos, D; Morand, EF, 2017)
"Pemphigus is a serious, potentially fatal chronic autoimmune bullous disease with cutaneous and mucosal manifestations."1.35[Epidemiology of pemphigus in the Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006]. ( Camacho, FM; Coronel-Pérez, IM; Pérez-Bernal, AM; Rodríguez-Rey, EM, 2009)
"Although pemphigus is a well-characterized entity, detailed epidemiologic studies from the Arabian Peninsula are not available."1.30Pemphigus in Kuwait. ( Al-Baghli, NM; Alsaleh, QA; Dvorak, R; Nanda, A, 1999)
" There was no increase in concurrent immunosuppressives dosage after the conversion."1.29Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation. ( Kaplan, MM; Pedrosa, MC; Rohrer, RM, 1995)
"Two paediatric patients with systemic lupus erythematosus were treated with immunoglobulin G (IgG)."1.27IgG therapy in systemic lupus erythematosus--two case reports. ( Dopfer, R; Gaedicke, G; Kohne, E; Niethammer, D; Teller, WM, 1984)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Apostolopoulos, D1
Morand, EF1
Coronel-Pérez, IM1
Rodríguez-Rey, EM1
Pérez-Bernal, AM1
Camacho, FM1
Bailin, PL1
Matkaluk, RM1
Gaedicke, G1
Teller, WM1
Kohne, E1
Dopfer, R1
Niethammer, D1
Pedrosa, MC1
Rohrer, RM1
Kaplan, MM1
Alsaleh, QA1
Nanda, A1
Al-Baghli, NM1
Dvorak, R1
Siegel, RR1
Luke, RG1
Hellebusch, AA1
Lingardh, G1
Andersson, L1
Osterman, B1
Breidenbach, H1
Krosse, C1
Schuster, W1
Potel, S1
Cade, R1
Spooner, G1
Schlein, E1
Pickering, M1
DeQuesada, A1
Holcomb, A1
Juncos, L1
Richard, G1
Shires, D1
Levin, D1
Hackett, R1
Free, J1
Hunt, R1
Fregly, M1
Stickel, DL1
Seigler, HF1
Amos, DB1
Ward, FE1
Gunnells, JC1
Price, AR1
Anderson, EE1
LaPlante, MP1
Kaufman, JJ1
Goldman, R1
Gonick, HC1
Martin, DC1
Goodwin, WE1
Nelius, D1
Stieglitz, R1
Baer, I1

Reviews

2 reviews available for azathioprine and Cushing's Syndrome

ArticleYear
It hasn't gone away: the problem of glucocorticoid use in lupus remains.
    Rheumatology (Oxford, England), 2017, 04-01, Volume: 56, Issue:suppl_1

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Cardiovascular Diseases; Cata

2017
Cutaneous reactions to rheumatological drugs.
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy

1982

Trials

1 trial available for azathioprine and Cushing's Syndrome

ArticleYear
Comparison of azathioprine, prednisone, and heparin alone or combined in treating lupus nephritis.
    Nephron, 1973, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Child; Cushing Syndrome; Diabetes Mellitus; Drug Combinations; Fema

1973

Other Studies

10 other studies available for azathioprine and Cushing's Syndrome

ArticleYear
[Epidemiology of pemphigus in the Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006].
    Actas dermo-sifiliograficas, 2009, Volume: 100, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cushing Syndrome; Drug Therapy, Combination; Fem

2009
IgG therapy in systemic lupus erythematosus--two case reports.
    Blut, 1984, Volume: 48, Issue:6

    Topics: Azathioprine; Child; Cushing Syndrome; Female; Humans; Immunoglobulin G; Lupus Erythematosus, System

1984
Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation.
    Clinical transplantation, 1995, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarc

1995
Pemphigus in Kuwait.
    International journal of dermatology, 1999, Volume: 38, Issue:5

    Topics: Age of Onset; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cushi

1999
Reduction of toxicity of corticosteroid therapy after renal transplantation.
    The American journal of medicine, 1972, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Cushing Syndrome; Female; Graft Rejection; Humans; Immunosuppressio

1972
Fertility in men after renal transplantation.
    Acta chirurgica Scandinavica, 1974, Volume: 140, Issue:6

    Topics: Adult; Atrophy; Azathioprine; Cushing Syndrome; Depression, Chemical; Erectile Dysfunction; Female;

1974
[Therapy of autoimmune thrombocytopenia in childhood].
    Kinderarztliche Praxis, 1972, Volume: 40, Issue:9

    Topics: Agranulocytosis; Autoimmune Diseases; Azathioprine; Child; Cushing Syndrome; Humans; Prednisone; Spl

1972
Immunogenetics of consanguineous allografts in man. II. Correlation of renal allografting with HL-A genotyping.
    Annals of surgery, 1970, Volume: 172, Issue:2

    Topics: Adolescent; Adult; Alleles; Azathioprine; Child; Cushing Syndrome; Female; Genetics, Medical; Glomer

1970
Kidney transplantation in children.
    Pediatrics, 1970, Volume: 46, Issue:5

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Body Height; Cadaver; Child; Child, Preschool; Cushi

1970
[Immunosuppressive therapy of autoimmune hemolytic anemias. (Preliminary report)].
    Allergie und Asthma, 1969, Volume: 15, Issue:4

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Cushing Syndrome; Female; Humans; Immunosu

1969