azathioprine has been researched along with Cushing Syndrome in 13 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These studies provide a compelling case for a re-evaluation of the long-term use of glucocorticoids in SLE, focusing on minimizing glucocorticoid exposure as part of the strategy to improve long-term outcomes." | 2.55 | It hasn't gone away: the problem of glucocorticoid use in lupus remains. ( Apostolopoulos, D; Morand, EF, 2017) |
| "Pemphigus is a serious, potentially fatal chronic autoimmune bullous disease with cutaneous and mucosal manifestations." | 1.35 | [Epidemiology of pemphigus in the Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006]. ( Camacho, FM; Coronel-Pérez, IM; Pérez-Bernal, AM; Rodríguez-Rey, EM, 2009) |
| "Although pemphigus is a well-characterized entity, detailed epidemiologic studies from the Arabian Peninsula are not available." | 1.30 | Pemphigus in Kuwait. ( Al-Baghli, NM; Alsaleh, QA; Dvorak, R; Nanda, A, 1999) |
| " There was no increase in concurrent immunosuppressives dosage after the conversion." | 1.29 | Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation. ( Kaplan, MM; Pedrosa, MC; Rohrer, RM, 1995) |
| "Two paediatric patients with systemic lupus erythematosus were treated with immunoglobulin G (IgG)." | 1.27 | IgG therapy in systemic lupus erythematosus--two case reports. ( Dopfer, R; Gaedicke, G; Kohne, E; Niethammer, D; Teller, WM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apostolopoulos, D | 1 |
| Morand, EF | 1 |
| Coronel-Pérez, IM | 1 |
| Rodríguez-Rey, EM | 1 |
| Pérez-Bernal, AM | 1 |
| Camacho, FM | 1 |
| Bailin, PL | 1 |
| Matkaluk, RM | 1 |
| Gaedicke, G | 1 |
| Teller, WM | 1 |
| Kohne, E | 1 |
| Dopfer, R | 1 |
| Niethammer, D | 1 |
| Pedrosa, MC | 1 |
| Rohrer, RM | 1 |
| Kaplan, MM | 1 |
| Alsaleh, QA | 1 |
| Nanda, A | 1 |
| Al-Baghli, NM | 1 |
| Dvorak, R | 1 |
| Siegel, RR | 1 |
| Luke, RG | 1 |
| Hellebusch, AA | 1 |
| Lingardh, G | 1 |
| Andersson, L | 1 |
| Osterman, B | 1 |
| Breidenbach, H | 1 |
| Krosse, C | 1 |
| Schuster, W | 1 |
| Potel, S | 1 |
| Cade, R | 1 |
| Spooner, G | 1 |
| Schlein, E | 1 |
| Pickering, M | 1 |
| DeQuesada, A | 1 |
| Holcomb, A | 1 |
| Juncos, L | 1 |
| Richard, G | 1 |
| Shires, D | 1 |
| Levin, D | 1 |
| Hackett, R | 1 |
| Free, J | 1 |
| Hunt, R | 1 |
| Fregly, M | 1 |
| Stickel, DL | 1 |
| Seigler, HF | 1 |
| Amos, DB | 1 |
| Ward, FE | 1 |
| Gunnells, JC | 1 |
| Price, AR | 1 |
| Anderson, EE | 1 |
| LaPlante, MP | 1 |
| Kaufman, JJ | 1 |
| Goldman, R | 1 |
| Gonick, HC | 1 |
| Martin, DC | 1 |
| Goodwin, WE | 1 |
| Nelius, D | 1 |
| Stieglitz, R | 1 |
| Baer, I | 1 |
2 reviews available for azathioprine and Cushing Syndrome
| Article | Year |
|---|---|
It hasn't gone away: the problem of glucocorticoid use in lupus remains.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Cardiovascular Diseases; Cata | 2017 |
Cutaneous reactions to rheumatological drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy | 1982 |
1 trial available for azathioprine and Cushing Syndrome
| Article | Year |
|---|---|
Comparison of azathioprine, prednisone, and heparin alone or combined in treating lupus nephritis.
Topics: Adolescent; Adult; Azathioprine; Child; Cushing Syndrome; Diabetes Mellitus; Drug Combinations; Fema | 1973 |
10 other studies available for azathioprine and Cushing Syndrome
| Article | Year |
|---|---|
[Epidemiology of pemphigus in the Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006].
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cushing Syndrome; Drug Therapy, Combination; Fem | 2009 |
IgG therapy in systemic lupus erythematosus--two case reports.
Topics: Azathioprine; Child; Cushing Syndrome; Female; Humans; Immunoglobulin G; Lupus Erythematosus, System | 1984 |
Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarc | 1995 |
Pemphigus in Kuwait.
Topics: Age of Onset; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cushi | 1999 |
Reduction of toxicity of corticosteroid therapy after renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Cushing Syndrome; Female; Graft Rejection; Humans; Immunosuppressio | 1972 |
Fertility in men after renal transplantation.
Topics: Adult; Atrophy; Azathioprine; Cushing Syndrome; Depression, Chemical; Erectile Dysfunction; Female; | 1974 |
[Therapy of autoimmune thrombocytopenia in childhood].
Topics: Agranulocytosis; Autoimmune Diseases; Azathioprine; Child; Cushing Syndrome; Humans; Prednisone; Spl | 1972 |
Immunogenetics of consanguineous allografts in man. II. Correlation of renal allografting with HL-A genotyping.
Topics: Adolescent; Adult; Alleles; Azathioprine; Child; Cushing Syndrome; Female; Genetics, Medical; Glomer | 1970 |
Kidney transplantation in children.
Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Body Height; Cadaver; Child; Child, Preschool; Cushi | 1970 |
[Immunosuppressive therapy of autoimmune hemolytic anemias. (Preliminary report)].
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Cushing Syndrome; Female; Humans; Immunosu | 1969 |