azathioprine has been researched along with Cruveilhier-Baumgarten Syndrome in 29 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Cruveilhier-Baumgarten Syndrome: Liver cirrhosis with intrahepatic portal obstruction, HYPERTENSION, and patent UMBILICAL VEINS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three cases of nodular regenerative hyperplasia of the liver associated with azathioprine therapy are reported." | 8.78 | [Nodular regenerative hyperplasia of the liver associated with azathioprine therapy]. ( Dhumeaux, D; Duvoux, C; Kracht, M; Lang, P; Vernant, JP; Zafrani, ES, 1991) |
| "We report the case of a 53-year-old man with Crohn's disease who developed azathioprine-induced nodular regenerative hyperplasia of the liver." | 7.77 | [Nodular regenerative hyperplasia: azathioprine-induced hepatotoxicity in a patient with Crohn's disease]. ( Corbatón, P; de la Fuente-Fernández, E; Gisbert, JP; López-Martín, C; Sánchez, MC, 2011) |
| "Twenty-seven patients with myasthenia gravis have been treated with azathioprine in conjunction with pyridostigmine and prednisolone for a total of 138 patient years." | 7.68 | Long term treatment of myasthenia gravis with azathioprine. ( Fonseca, V; Havard, CW, 1990) |
| "A 52 year old man with myasthenia gravis and normal liver function was treated with neostigmine, prednisolone and azathioprine." | 7.67 | Portal hypertension secondary to azathioprine in myasthenia gravis. ( Fonseca, V; Havard, CW, 1988) |
| "Three cases of nodular regenerative hyperplasia of the liver associated with azathioprine therapy are reported." | 4.78 | [Nodular regenerative hyperplasia of the liver associated with azathioprine therapy]. ( Dhumeaux, D; Duvoux, C; Kracht, M; Lang, P; Vernant, JP; Zafrani, ES, 1991) |
| "We report the case of a 53-year-old man with Crohn's disease who developed azathioprine-induced nodular regenerative hyperplasia of the liver." | 3.77 | [Nodular regenerative hyperplasia: azathioprine-induced hepatotoxicity in a patient with Crohn's disease]. ( Corbatón, P; de la Fuente-Fernández, E; Gisbert, JP; López-Martín, C; Sánchez, MC, 2011) |
| " Both patients had been treated with azathioprine and prednisolone for 6 years and 4 months and for 4 years and 7 months, respectively, and presented with splenomegaly and thrombocytopenia suggesting hypersplenism." | 3.69 | Idiopathic portal hypertension in renal transplant recipients: report of two cases. ( Kobashi, T; Kohnosu, H; Ohmori, Y; Oka, T; Yasumura, T; Yoshimura, N, 1994) |
| "Twenty-seven patients with myasthenia gravis have been treated with azathioprine in conjunction with pyridostigmine and prednisolone for a total of 138 patient years." | 3.68 | Long term treatment of myasthenia gravis with azathioprine. ( Fonseca, V; Havard, CW, 1990) |
| "A 52 year old man with myasthenia gravis and normal liver function was treated with neostigmine, prednisolone and azathioprine." | 3.67 | Portal hypertension secondary to azathioprine in myasthenia gravis. ( Fonseca, V; Havard, CW, 1988) |
| "Factors associated with HCV recurrence were evaluated." | 2.79 | Reduced fibrosis in recurrent HCV with tacrolimus, azathioprine and steroids versus tacrolimus: randomised trial long term outcomes. ( Burroughs, AK; Cholongitas, E; Corbani, A; Davidson, B; Davidson, J; Dhillon, AP; Hayes, P; Luong, T; Manousou, P; McCormick, PA; O'Beirne, J; Patch, D; Rodríguez-Perálvarez, M; Rolles, K; Samonakis, D; Thorburn, D; Tsochatzis, E, 2014) |
| "The fibroscan data showed significant liver fibrosis (F2-F3)." | 1.43 | Idiopathic portal hypertension regarding thiopurine treatment in patients with inflammatory bowel disease. ( Abreu García, L; Calleja Panero, JL; Calvo Moya, M; González Lama, Y; González Partida, I; Llop Herrera, E; Matallana Royo, V; Suárez Ferrer, C; Vera Mendoza, MI, 2016) |
| "Azathioprine is a useful agent for the treatment of Crohn's disease but side effects occur in 10% of patients." | 1.31 | Portal hypertension in the presence of minimal liver damage in Crohn's disease on long-term azathioprine: possible endothelial cell injury. ( Arnott, ID; Ghosh, S, 2000) |
| "Treatment with azathioprine and prednisolone for immunosuppression had been discontinued 1 year before admission." | 1.28 | Idiopathic portal hypertension in a renal transplant patient after long-term azathioprine therapy. ( Becker, K; Brauer, M; Classen, M; Lorenz, R; Tornieporth, N, 1992) |
| "Azathioprine was discontinued." | 1.27 | Hepatic vascular disease after kidney transplantation: report of two cases and review of the literature. ( Adler, M; Cremer, M; De Pauw, L; Delhaye, M; Deprez, C; Gelin, M; Hardy, N; Toussaint, C; Vereerstraeten, P, 1987) |
| " These observations strongly suggest an association between chronic use of azathioprine and the development of venous congestion of the liver with sinusoidal dilatation, eventually resulting in chronic liver disease." | 1.27 | Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment after kidney transplantation. ( Assmann, KM; Deckers, PF; Driessen, WM; Gerlag, PG; Lobatto, S; Schröder, E; Van Haelst, UJ; Van Hooff, JP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (31.03) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Lanis, A | 1 |
| Volochayev, R | 1 |
| Kleiner, DE | 1 |
| Vittal, A | 1 |
| Heller, T | 1 |
| Rider, LG | 1 |
| Shenoi, S | 1 |
| Gilissen, LPL | 1 |
| Tajzai, R | 1 |
| Romberg, M | 1 |
| Pierik, M | 1 |
| Stronkhorst, A | 1 |
| Steenhuisen, K | 1 |
| Van Bodegraven, A | 1 |
| Daniels, A | 1 |
| Wong, D | 1 |
| Manousou, P | 2 |
| Cholongitas, E | 2 |
| Samonakis, D | 2 |
| Tsochatzis, E | 1 |
| Corbani, A | 1 |
| Dhillon, AP | 2 |
| Davidson, J | 1 |
| Rodríguez-Perálvarez, M | 1 |
| Patch, D | 2 |
| O'Beirne, J | 2 |
| Thorburn, D | 1 |
| Luong, T | 1 |
| Rolles, K | 2 |
| Davidson, B | 1 |
| McCormick, PA | 1 |
| Hayes, P | 2 |
| Burroughs, AK | 2 |
| Dooremont, D | 1 |
| Decaestecker, J | 1 |
| De Wulf, D | 1 |
| Ghillebert, G | 1 |
| Van Vlierberghe, H | 1 |
| Van Dorpe, J | 1 |
| Baert, F | 1 |
| Suárez Ferrer, C | 1 |
| Llop Herrera, E | 1 |
| Calvo Moya, M | 1 |
| Vera Mendoza, MI | 1 |
| González Partida, I | 1 |
| González Lama, Y | 1 |
| Matallana Royo, V | 1 |
| Calleja Panero, JL | 1 |
| Abreu García, L | 1 |
| McCormick, A | 1 |
| López-Martín, C | 1 |
| de la Fuente-Fernández, E | 1 |
| Corbatón, P | 1 |
| Sánchez, MC | 1 |
| Gisbert, JP | 1 |
| Calabrese, E | 1 |
| Hanauer, SB | 1 |
| Vernier-Massouille, G | 1 |
| Cosnes, J | 1 |
| Lemann, M | 1 |
| Marteau, P | 1 |
| Reinisch, W | 1 |
| Laharie, D | 1 |
| Cadiot, G | 1 |
| Bouhnik, Y | 1 |
| De Vos, M | 1 |
| Boureille, A | 1 |
| Duclos, B | 1 |
| Seksik, P | 1 |
| Mary, JY | 1 |
| Colombel, JF | 1 |
| Ehmsen, L | 1 |
| Marko, C | 1 |
| Breidert, M | 1 |
| Noël, C | 1 |
| Hazzan, M | 1 |
| Coppin, MC | 1 |
| Bridoux, F | 1 |
| Codaccioni, MX | 1 |
| Pruvot, FR | 1 |
| Yoshimura, N | 1 |
| Oka, T | 1 |
| Ohmori, Y | 1 |
| Yasumura, T | 1 |
| Kohnosu, H | 1 |
| Kobashi, T | 1 |
| Elariny, HA | 1 |
| Mizrahi, SS | 1 |
| Hayes, DH | 1 |
| Boudreaux, JP | 1 |
| Hussey, JL | 1 |
| Farr, GH | 1 |
| Gane, E | 1 |
| Portmann, B | 1 |
| Saxena, R | 1 |
| Wong, P | 1 |
| Ramage, J | 1 |
| Williams, R | 2 |
| Roland, S | 1 |
| Delwaide, J | 1 |
| Cornet, G | 1 |
| Mahieu, P | 1 |
| Jacquet, N | 1 |
| Belaiche, J | 1 |
| Arnott, ID | 1 |
| Ghosh, S | 1 |
| Nataf, C | 1 |
| Feldmann, G | 1 |
| Lebrec, D | 1 |
| Degott, C | 1 |
| Descamps, JM | 1 |
| Rueff, B | 1 |
| Benhamou, JP | 1 |
| Cello, JP | 1 |
| Lorenz, R | 1 |
| Brauer, M | 1 |
| Classen, M | 1 |
| Tornieporth, N | 1 |
| Becker, K | 1 |
| Duvoux, C | 1 |
| Kracht, M | 1 |
| Lang, P | 1 |
| Vernant, JP | 1 |
| Zafrani, ES | 1 |
| Dhumeaux, D | 1 |
| Fonseca, V | 2 |
| Havard, CW | 2 |
| Yanagisawa, N | 1 |
| Sugaya, H | 1 |
| Yunomura, K | 1 |
| Harada, T | 1 |
| Hisauchi, T | 1 |
| Read, AE | 1 |
| Wiesner, RH | 1 |
| LaBrecque, DR | 1 |
| Tifft, JG | 1 |
| Mullen, KD | 1 |
| Sheer, RL | 1 |
| Petrelli, M | 1 |
| Ricanati, ES | 1 |
| McCullough, AJ | 1 |
| Adler, M | 1 |
| Delhaye, M | 1 |
| Deprez, C | 1 |
| Hardy, N | 1 |
| Gelin, M | 1 |
| De Pauw, L | 1 |
| Vereerstraeten, P | 1 |
| Cremer, M | 1 |
| Toussaint, C | 1 |
| Gerlag, PG | 2 |
| van Hooff, JP | 2 |
| Warnes, TW | 1 |
| Lobatto, S | 1 |
| Driessen, WM | 1 |
| Deckers, PF | 1 |
| Schröder, E | 1 |
| Assmann, KM | 1 |
| Van Haelst, UJ | 1 |
| Murray-Lyon, IM | 1 |
| Stern, RB | 1 |
5 reviews available for azathioprine and Cruveilhier-Baumgarten Syndrome
| Article | Year |
|---|---|
Azathioprine induced serious portal hypertension: a case series of three IBD patients and review of the literature.
Topics: Adult; Azathioprine; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Dise | 2013 |
Assessment of non-cirrhotic portal hypertension associated with thiopurine therapy in inflammatory bowel disease.
Topics: Azathioprine; Crohn Disease; Humans; Hypertension, Portal; Immunosuppressive Agents; Liver; Male; Me | 2011 |
Nodular regenerative hyperplasia: a controversial indication for orthotopic liver transplantation.
Topics: Adult; Azathioprine; Female; Humans; Hyperplasia; Hypertension, Portal; Kidney Transplantation; Live | 1994 |
[Nodular regenerative hyperplasia of the liver associated with azathioprine therapy].
Topics: Adult; Azathioprine; Graft vs Host Disease; Humans; Hyperplasia; Hypertension, Portal; Immunosuppres | 1991 |
Treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine | 1985 |
3 trials available for azathioprine and Cruveilhier-Baumgarten Syndrome
| Article | Year |
|---|---|
Reduced fibrosis in recurrent HCV with tacrolimus, azathioprine and steroids versus tacrolimus: randomised trial long term outcomes.
Topics: Anti-Inflammatory Agents; Azathioprine; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Hum | 2014 |
Outcome of recurrent hepatitis C virus after liver transplantation in a randomized trial of tacrolimus monotherapy versus triple therapy.
Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Child; Drug Therapy, Combination; Female; Graft Rejec | 2009 |
Controlled trial of prednisone and azathioprine in active chronic hepatitis.
Topics: Adult; Alkaline Phosphatase; Antibodies; Antibodies, Antinuclear; Aspartate Aminotransferases; Azath | 1973 |
21 other studies available for azathioprine and Cruveilhier-Baumgarten Syndrome
| Article | Year |
|---|---|
Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis.
Topics: Abatacept; Adolescent; Arthritis; Autoantibodies; Azathioprine; Calcinosis; Child; Cyclophosphamide; | 2022 |
The prevalence of nodular regenerative hyperplasia of the liver in long-term thiopurine-treated inflammatory bowel disease patients.
Topics: Azathioprine; Chronic Disease; Cross-Sectional Studies; Humans; Hyperplasia; Hypertension, Portal; I | 2021 |
Idiopathic portal hypertension regarding thiopurine treatment in patients with inflammatory bowel disease.
Topics: Adult; Aged; Azathioprine; Cross-Sectional Studies; Female; Humans; Hypertension, Portal; Idiopathic | 2016 |
[Nodular regenerative hyperplasia: azathioprine-induced hepatotoxicity in a patient with Crohn's disease].
Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Crohn Disease; Humans; Hyperplasia; Hypertensi | 2011 |
Nodular regenerative hyperplasia in patients with inflammatory bowel disease treated with azathioprine.
Topics: Adolescent; Adult; Azathioprine; Child; Epidemiologic Methods; Europe; Female; Focal Nodular Hyperpl | 2007 |
[Portal vein hypertension during azathioprine therapy in patients with Crohn's disease--a frequent phenomenon?].
Topics: Azathioprine; Crohn Disease; Enbucrilate; Esophageal and Gastric Varices; Focal Nodular Hyperplasia; | 2008 |
Idiopathic portal hypertension: an infrequent complication of renal transplantation.
Topics: Adult; Azathioprine; Cytomegalovirus Infections; Esophageal and Gastric Varices; Follow-Up Studies; | 1995 |
Idiopathic portal hypertension in renal transplant recipients: report of two cases.
Topics: Adult; Angiography; Azathioprine; Catheterization; Celiac Artery; Endoscopy; Esophageal and Gastric | 1994 |
Nodular regenerative hyperplasia of the liver graft after liver transplantation.
Topics: Adult; Azathioprine; Biopsy; Female; Humans; Hyperplasia; Hypertension, Portal; Liver; Liver Functio | 1994 |
[Clinical case of the month. Hepatoportal sclerosis in a patient treated with azathioprine].
Topics: Adult; Ascites; Azathioprine; Chemical and Drug Induced Liver Injury; Cholestasis; Diagnosis, Differ | 1998 |
Portal hypertension in the presence of minimal liver damage in Crohn's disease on long-term azathioprine: possible endothelial cell injury.
Topics: Adult; Azathioprine; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; | 2000 |
Idiopathic portal hypertension (perisinusoidal fibrosis) after renal transplantation.
Topics: Adult; Azathioprine; Humans; Hypertension, Portal; Kidney Transplantation; Liver; Male; Mercaptopuri | 1979 |
Cholestasis in ulcerative colitis. Long term complications and medical therapy.
Topics: Anti-Bacterial Agents; Azathioprine; Bacterial Infections; Bile Acids and Salts; Cholangitis; Cholel | 1977 |
Idiopathic portal hypertension in a renal transplant patient after long-term azathioprine therapy.
Topics: Angiography; Azathioprine; Biopsy; Esophageal and Gastric Varices; Graft Rejection; Humans; Hyperten | 1992 |
Long term treatment of myasthenia gravis with azathioprine.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; Jaundice; Long | 1990 |
A case of idiopathic portal hypertension after renal transplantation.
Topics: Adult; Azathioprine; Biopsy; Humans; Hypertension, Portal; Immunosuppression Therapy; Kidney Transpl | 1990 |
Hepatic veno-occlusive disease associated with renal transplantation and azathioprine therapy.
Topics: Adult; Azathioprine; Cyclophosphamide; Cytomegalovirus Infections; Esophageal and Gastric Varices; F | 1986 |
Hepatic vascular disease after kidney transplantation: report of two cases and review of the literature.
Topics: Adult; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Hepatic Veins; Hepatic Veno-Occ | 1987 |
Portal hypertension secondary to azathioprine in myasthenia gravis.
Topics: Azathioprine; Humans; Hypertension, Portal; Liver; Male; Middle Aged; Myasthenia Gravis | 1988 |
Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment: a cause of chronic liver disease after kidney transplantation.
Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Humans; Hypert | 1987 |
Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment after kidney transplantation.
Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Esophagus; Female; Humans; Hypertension | 1985 |