Page last updated: 2024-10-23

azathioprine and Coronary Disease

azathioprine has been researched along with Coronary Disease in 50 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Treatment with azathioprine or mycophenolate did not affect PV or PI in either the SRL group (PV: 0."2.73Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation. ( Bae, JH; Clavell, AL; Edwards, BS; Frantz, RP; Khalpey, Z; Kremers, WK; Kushwaha, SS; Lerman, A; Raichlin, E; Rihal, C; Rodeheffer, RJ, 2007)
"Everolimus was more efficacious than azathioprine in reducing the severity and incidence of cardiac-allograft vasculopathy, suggesting that everolimus therapy may alleviate this serious problem."2.71Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients. ( Abeywickrama, KH; Bernhardt, P; Dorent, R; Eisen, HJ; Hummel, M; Kobashigawa, J; Lind, JM; Mancini, D; Starling, RC; Sørensen, K; Tuzcu, EM; Valantine-von Kaeppler, HA, 2003)
"Graft coronary disease was found in 8 patients (11%), 2 were re-transplanted and have survived 4."1.33Ten year survival after paediatric heart transplantation: a single centre experience. ( Khaghani, A; Smith, RR; Wray, J; Yacoub, M, 2005)
"Coronary heart disease was also more frequent in PTDM (15 vs."1.31High incidence of post-transplant diabetes mellitus in Kuwait. ( Al-Mousawi, M; Costandi, JN; Gupta, RK; Johny, KV; Muzairai, I; Nampoory, MR; Ninan, VT; Samhan, M, 2002)
"Hypertension is a common concomitant condition in renal transplant recipients."1.30Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients. ( Bölscher, S; Geiger, H; Kachel, HG; Lenz, T; Peschke, B; Scheuermann, EH, 1999)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199021 (42.00)18.7374
1990's13 (26.00)18.2507
2000's16 (32.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
John, R1
Lietz, K1
Schuster, M1
Naka, Y1
Rao, V1
Mancini, DM1
Rose, EA3
Smith, CR2
Oz, MC1
Edwards, NM1
Itescu, S1
Tedesco Silva, H1
Felipe, CR1
Machado, PG1
Garcia, R1
Motegi, S1
Hosaka, BH1
Hanzawa, NM1
Park, SI1
Casarini, D1
Lima, VC1
Franco, M1
Medina-Pestana, JO1
Avery, RK1
Eisen, HJ1
Tuzcu, EM1
Dorent, R1
Kobashigawa, J1
Mancini, D1
Valantine-von Kaeppler, HA1
Starling, RC1
Sørensen, K1
Hummel, M1
Lind, JM1
Abeywickrama, KH1
Bernhardt, P1
Banas, B1
Böger, C1
Krämer, B1
El-Sayed, O1
Magorien, RD1
Orsini, A1
Ferketich, AK1
Leier, CV1
Valantine, H2
Smith, RR1
Wray, J1
Khaghani, A3
Yacoub, M2
Li, HY1
Tanaka, K1
Oeser, B1
Wertman, B1
Kobashigawa, JA1
Tobis, JM1
Kaczmarek, I1
Ertl, B1
Schmauss, D1
Sadoni, S1
Knez, A1
Daebritz, S1
Meiser, B1
Reichart, B2
Raichlin, E1
Bae, JH1
Khalpey, Z1
Edwards, BS1
Kremers, WK1
Clavell, AL1
Rodeheffer, RJ1
Frantz, RP1
Rihal, C1
Lerman, A1
Kushwaha, SS1
Mudge, GH1
Annemans, L1
Lemkuhl, H1
Tenderich, G1
Schulz, U1
Yang, XL1
Ricci, JF1
Hetzer, R2
Hosenpud, JD1
Montanaro, A1
Hart, MV1
Haines, JE1
Specht, HD1
Bennett, RM1
Kloster, FE1
Chrétien, J1
Hunt, S1
Gamberg, P1
Miller, J1
Luikart, H1
Wahlers, T1
Mügge, A1
Oppelt, P1
Heublein, B1
Fieguth, HG1
Jurmann, M1
Haverich, A1
Addonizio, LJ1
Hsu, DT1
Douglas, JF1
Kichuk, MR1
Michler, RE1
Quaegebeur, JM1
Stapleton, DD1
Ventura, HO1
Grundtner, SE1
Smart, FW1
Price, HL1
Van Meter, C1
Ochsner, JL1
Pham, SM1
Kormos, RL1
Kawai, A1
Murali, S1
Hattler, BG1
Demetris, AJ1
Griffith, BP1
Gajarski, RJ1
Smith, EO1
Denfield, SW1
Rosenblatt, HM1
Kearney, D1
Frazier, OH1
Radovancevic, B1
Price, JK1
Kertesz, NJ1
Towbin, JA1
Peddi, VR1
Whiting, J1
Weiskittel, PD1
Alexander, JW1
First, MR1
Frustaci, A2
Chimenti, C2
Maseri, A2
Pieroni, M1
Peschke, B1
Scheuermann, EH1
Geiger, H1
Bölscher, S1
Kachel, HG1
Lenz, T1
Sánchez, V1
Delgado, JF1
Blasco, T1
Dalmau, R1
Morales, JM1
Escribano, P1
Tello, R1
Hernández, J1
Velázquez, T1
Sotelo, T1
Gómez-Sánchez, MA1
Sáenz de la Calzada, C1
Barr, ML1
Baker, CJ1
Schenkel, FA1
McLaughlin, SN1
Stouch, BC1
Starnes, VA1
Johny, KV1
Nampoory, MR1
Costandi, JN1
Gupta, RK1
Ninan, VT1
Samhan, M1
Muzairai, I1
Al-Mousawi, M1
Hennersdorf, F1
Wellnhofer, E1
Musci, M1
Bocksch, W1
Spiegelsberger, S1
Heins, S1
Fleck, E1
Schroeder, JS3
Rider, AK2
Stinson, EB5
Shumway, NE3
Barnard, CN1
Delmonico, FL1
Cosimi, AB1
Russell, PS1
Barbir, M1
Banner, N1
Thompson, GR1
Mitchell, A1
Olivari, MT2
Kubo, SH2
Braunlin, EA1
Bolman, RM1
Ring, WS2
Aravot, DJ1
Banner, NR1
Fitzgerald, M1
Radley-Smith, R1
Mitchell, AG1
Yacoub, MH1
Gao, SZ1
Alderman, EL1
Hunt, SA1
Valantine, HA1
Wiederhold, V1
Homans, DC1
Wilson, RF1
Becerra, E1
Cooper, DK1
Novitzky, D1
Baumgartner, WA1
Augustine, S1
Borkon, AM1
Gardner, TJ1
Reitz, BA1
Hess, ML1
Hastillo, A1
Thompson, JA1
Sansonetti, DJ1
Szentpetery, S1
Barnhart, G1
Lower, RR2
Jordan, ML1
Novick, AC1
Steinmuller, D1
Braun, W1
Buszta, C1
Mintz, D1
Goormastic, M1
Streem, S1
Laden, AM1
Ruszkiewicz, M1
Graham, AF1
Caves, PK1
Harrison, DC1
Hollander, CF1
Cooley, DA1
Messmer, BJ1
Hallman, GL1
Bloodwell, RD1
Nora, JJ1
Leachman, RD1
Goldstein, HM1
Castellino, RA1
Wexler, L1
Dong, E1
Bieber, CP1
Popp, RL1
Chatty, ME1
Deodhar, SD1
Dubost, C1
Cachera, JP1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylaxis of the Graft-Versus-Host-Disease in Patients After Allogeneic Stem Cell Transplantation With a Combination of Tacrolimus and Everolimus[NCT00117702]Phase 2/Phase 324 participants (Actual)Interventional2005-10-31Terminated (stopped due to safety reasons)
Safety and Efficacy of Low-dose Cyclosporine in Association With Everolimus to Minimize Renal Dysfunction in Heart Transplant Recipients[NCT00420537]Phase 434 participants (Actual)Interventional2006-09-30Terminated (stopped due to A cluster of adverse events in everolimus arm was noted.)
A Phase II Trial of RAD001 in Triple Negative Metastatic Breast Cancer[NCT00827567]Phase 26 participants (Actual)Interventional2009-04-30Terminated (stopped due to Slow accrual)
A Randomized Prospective Trial of Conversion to Everolimus Therapy From Calcineurin Inhibitor Based Maintenance Immunosuppression in Association With Mycophenolic Acid in Liver Transplantation: Examination of Impact on Long Term Renal Function.[NCT01936519]24 participants (Actual)Interventional2013-12-16Completed
Early Vs Late Sirolimus-Initiation Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant Recipients[NCT01305395]0 participants (Actual)Interventional2010-11-30Withdrawn (stopped due to Due in part, to reduced transplant volume and enrollment has been difficult.)
Cardiac Allograft Remodeling and Effects of Sirolimus on Its Progression[NCT01889992]Phase 142 participants (Actual)Interventional2013-04-24Terminated (stopped due to PI left University and project not continued)
Impact of Photopheresis in the Prevention of Acute Rejection in Highly Sensitized de Novo Kidney Transplant Recipients[NCT04414735]30 participants (Anticipated)Interventional2022-08-17Recruiting
The Use of Extracorporeal Photopheresis as Immunomodulatory Therapy of Subclinical Antibody-mediated Rejection After Lung Transplantation: a Prospective RCT[NCT06112951]80 participants (Anticipated)Interventional2023-11-01Not yet recruiting
Prospective, Observational Trial of Biological or Prosthetic Mesh for Open Ventral Hernia Repair[NCT03317665]28 participants (Actual)Observational2019-02-11Terminated (stopped due to Premature termination due to cease of funding)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Recipient and Donor Genotyping for Selected Variants of CYP3A5, ABCB1 (MDR1), and CYP4A Genes

A blood sample was obtained from recipients and donors to measure gene polymorphism effects on metabolism of calcineurin inhibitor and everolimus. The polymorphisms are represented as the number of SNP occurrences for the CYP3A5, ABCB1 (MDR1) gene, and CYP4A4*22 genes. (NCT01936519)
Timeframe: 2 years

,
InterventionParticipants (Count of Participants)
Recipient Genotypes : rs776746 (CYP3A5 gene)Recipient Genotypes : rs1045642 (ABCB1 gene)Recipient Genotypes : rs1128503 (ABCB1 gene)Recipient Genotypes : rs2032582 (ABCB1 gene)Recipient Genotypes : rs35599367 (CYP4A4*22 gene)Donor Genotypes : rs776746 (CYP3A5 gene)Donor Genotypes : rs1045642 (ABCB1 gene)Donor Genotypes : rs1128503 (ABCB1 gene)Donor Genotypes : rs2032582 (ABCB1 gene)Donor Genotypes : rs35599367 (Cyp4A4*22)
Calcineurin Inhibitor and Mycophenolic Acid11671131000
Everolimus and Mycophenolic Acid11680105001

Renal Function as Measured by 24 Hour Urine Creatinine Clearance

Renal Function was assessed by 24 hr urine collection creatinine clearance measured (mL/min). 24 Hr urine collection was assessed at baseline, 6 months, 1 year, and 2 years post transplant. (NCT01936519)
Timeframe: 6 months, 1 year, and 2 years

,
InterventionmL/min (Mean)
24hr Urine Creatinine Clearance at 6 months24hr Urine Creatinine Clearance at 1 year24hr Urine Creatinine Clearance at 2 years
Calcineurin Inhibitor With Mycophenolic Acid68.0968.0961.54
Everolimus With Mycophenolic Acid70.7586.890.63

Renal Function as Measured by Cockcroft Gault Creatinine Clearance

The Cockcroft-Gault formula for estimating creatinine clearance was determined at 6 months, 1 year, and 2 years post transplant (NCT01936519)
Timeframe: 6 months, 1 year, and 2 years

,
InterventionmL/min/1.73m2 (Mean)
Cockcroft Gault Creatinine Clearance at 6 monthsCockcroft Gault Creatinine Clearance at 1 yearCockcroft Gault Creatinine Clearance at 2 years
Calcineurin Inhibitor and Mycophenolic Acid79.8486.8480.85
Everolimus and Mycophenolic Acid100.17113.47108.16

Renal Function as Measured by Iothalamate Clearance

Iothalamate Clearance was assessed at 6 months, 1 year, and 2 years post transplant. (NCT01936519)
Timeframe: 6 months, 1 year, and 2 years

,
InterventionmL/min/1.73m2 (Mean)
Iothalamate Clearance at 6 monthsIothalamate Clearance at 1 yearIothalamate Clearance at 2 years
Calcineurin Inhibitor and Mycophenolic Acid67.9966.6557.19
Everolimus and Mycophenolic Acid74.23104.0179.41

Renal Function as Measured by Modification of Diet in Renal Disease (MDRD) Estimated Glomerular Filtration Rate (eGFR)

Modification of Diet in Renal Disease (MDRD) estimated Glomerular Filtration Rate (eGFR) was assessed at 6 months, 1 year, and 2 years post transplant. (NCT01936519)
Timeframe: 6 months, 1 year, and 2 years

,
InterventionmL/min/1.73 m2 (Mean)
MDRD eGFR at 6 monthsMDRD eGFR at 1 yearMDRD eGFR at 2 years
Calcineurin Inhibitor and Mycophenolic Acid62.1860.6353.29
Everolimus and Mycophenolic Acid81.2788.0187.37

Renal Function as Measured by Serum Creatinine Level

Serum creatinine levels were assessed at 6 months, 1 year, and 2 years post transplant (NCT01936519)
Timeframe: 6 months, 1 year, and 2 years

,
Interventionmg/dL (Mean)
Serum Creatinine at 6 monthsSerum Creatinine at 1 yearSerum Creatinine at 2 years
Calcineurin Inhibitor and Mycophenolic Acid1.291.291.51
Everolimus and Mycophenolic Acid1.020.950.95

Reviews

1 review available for azathioprine and Coronary Disease

ArticleYear
Current status of clinical cardiac transplantation.
    Transplantation proceedings, 1974, Volume: 6, Issue:4 Suppl 1

    Topics: Adult; Arteriosclerosis; Azathioprine; B-Lymphocytes; Brain Death; Cardiac Catheterization; Cardiomy

1974

Trials

9 trials available for azathioprine and Coronary Disease

ArticleYear
Safety and efficacy of sirolimus in kidney transplant patients and in patients with coronary artery disease undergoing angioplasty.
    Transplantation proceedings, 2003, Volume: 35, Issue:3 Suppl

    Topics: Adult; Angioplasty, Balloon, Coronary; Azathioprine; Black People; Cadaver; Coronary Disease; Cyclos

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Cyclosporine; Cytomegalovirus Infecti

2003
Advancing immunosuppression therapy to counter the progression of cardiac allograft vasculopathy.
    Journal of cardiac failure, 2005, Volume: 11, Issue:2

    Topics: Azathioprine; Coronary Angiography; Coronary Disease; Cyclosporine; Drug Therapy, Combination; Femal

2005
Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Coronary Disease; Female; Heart Transplantation;

2007
Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Coronary Disease; Female; Heart Transplantation;

2007
Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Coronary Disease; Female; Heart Transplantation;

2007
Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Coronary Disease; Female; Heart Transplantation;

2007
Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation.
    Transplantation proceedings, 2007, Volume: 39, Issue:10

    Topics: Acute Disease; Adult; Azathioprine; Belgium; Cardiomyopathy, Dilated; Coronary Disease; Cost of Illn

2007
Coronary vasculopathy following cardiac transplantation and cyclosporine immunosuppression: preventive treatment with angiopeptin, a somatostatin analog.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Coronary Disease; Cyclosporine; Female; Heart

1994
Induction immunosuppression with the monoclonal antibody OKT3 after cardiac transplantation.
    The American journal of the medical sciences, 1993, Volume: 306, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Coronary Disease; Creatinine; Cyclosporine; Drug Thera

1993
Tacrolimus (FK 506) in clinical cardiac transplantation: a five-year experience.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Communicable Diseases; Coronary Disease; Cyclosporine; Dr

1996
Prophylactic photopheresis and chronic rejection: effects on graft intimal hyperplasia in cardiac transplantation.
    Clinical transplantation, 2000, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antibodies; Azathioprine; Chronic Disease; Coronary Disease; Coronary Vessels; Cy

2000
Prophylactic photopheresis and chronic rejection: effects on graft intimal hyperplasia in cardiac transplantation.
    Clinical transplantation, 2000, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antibodies; Azathioprine; Chronic Disease; Coronary Disease; Coronary Vessels; Cy

2000
Prophylactic photopheresis and chronic rejection: effects on graft intimal hyperplasia in cardiac transplantation.
    Clinical transplantation, 2000, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antibodies; Azathioprine; Chronic Disease; Coronary Disease; Coronary Vessels; Cy

2000
Prophylactic photopheresis and chronic rejection: effects on graft intimal hyperplasia in cardiac transplantation.
    Clinical transplantation, 2000, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antibodies; Azathioprine; Chronic Disease; Coronary Disease; Coronary Vessels; Cy

2000

Other Studies

40 other studies available for azathioprine and Coronary Disease

ArticleYear
Immunologic sensitization in recipients of left ventricular assist devices.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:3

    Topics: Actuarial Analysis; Acute Disease; Aged; Anti-Inflammatory Agents; Azathioprine; Coronary Disease; C

2003
Cardiac-allograft vasculopathy.
    The New England journal of medicine, 2003, Aug-28, Volume: 349, Issue:9

    Topics: Azathioprine; Coronary Disease; Cytomegalovirus Infections; Drug Therapy, Combination; Everolimus; H

2003
Everolimus in cardiac-transplant recipients.
    The New England journal of medicine, 2003, Dec-04, Volume: 349, Issue:23

    Topics: Azathioprine; Coronary Disease; Coronary Vessels; Everolimus; Graft Rejection; Heart Transplantation

2003
Prevention of cardiac allograft vasculopathy with Certican (everolimus): the Stanford University experience within the Certican Phase III clinical trial.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:4 Suppl

    Topics: Adult; Angioplasty, Balloon, Coronary; Azathioprine; Clinical Trials, Phase III as Topic; Coronary D

2005
Ten year survival after paediatric heart transplantation: a single centre experience.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2005, Volume: 27, Issue:5

    Topics: Azathioprine; Cardiomyopathies; Child; Child, Preschool; Coronary Angiography; Coronary Disease; Cyc

2005
Compensatory enlargement in transplant coronary artery disease: an intravascular ultrasound study.
    Chinese medical journal, 2006, Apr-05, Volume: 119, Issue:7

    Topics: Adult; Aged; Azathioprine; Coronary Disease; Coronary Vessels; Female; Heart Transplantation; Humans

2006
Preventing cardiac allograft vasculopathy: long-term beneficial effects of mycophenolate mofetil.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2006, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Azathioprine; Coronary Disease; Disease Progression; Heart Transplantation;

2006
Sirolimus and cardiac transplantation: is it the "magic bullet"?
    Circulation, 2007, Dec-04, Volume: 116, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Coronary Disease; Female; Heart Transplantation;

2007
Myocardial perfusion abnormalities in asymptomatic patients with systemic lupus erythematosus.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Cicatrix; Coronary Disease; Exercise Test; Female; Heart; Humans; L

1984
[Idiopathic fibrogenous interstitial pneumopathy].
    Schweizerische medizinische Wochenschrift, 1980, Dec-06, Volume: 110, Issue:49

    Topics: Adrenal Cortex Hormones; Azathioprine; Coronary Disease; Humans; Lung; Lung Neoplasms; Pulmonary Fib

1980
Impact of cyclosporine dose on long-term outcome after heart transplantation.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Actuarial Analysis; Antilymphocyte Serum; Azathioprine; Coronary Disease; Cyclosporine; Dose-Respons

1994
Decreasing incidence of coronary disease in pediatric cardiac transplant recipients using increased immunosuppression.
    Circulation, 1993, Volume: 88, Issue:5 Pt 2

    Topics: Azathioprine; Child; Coronary Angiography; Coronary Disease; Cyclosporine; Follow-Up Studies; Graft

1993
Long-term results of triple-drug-based immunosuppression in nonneonatal pediatric heart transplant recipients.
    Transplantation, 1998, Jun-15, Volume: 65, Issue:11

    Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Coronary Disease; Cyclosporine; Drug Thera

1998
Characteristics of long-term renal transplant survivors.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Cadaver; Child; Child, Preschool; Coronary Disease; Female; Follow-

1998
Global biventricular dysfunction in patients with asymptomatic coronary artery disease may be caused by myocarditis.
    Circulation, 1999, Mar-16, Volume: 99, Issue:10

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Autoimmune Diseases; Azathioprine; Biopsy; Cardiomy

1999
Histologically proven myocarditis in patients with biventricular dysfunction and severe asymptomatic coronary artery disease.
    Cardiologia (Rome, Italy), 1999, Volume: 44, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Coronary Angiography; Coronary Disease; Echoc

1999
Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients.
    Clinical nephrology, 1999, Volume: 51, Issue:5

    Topics: Azathioprine; Coronary Disease; Cyclosporine; Graft Rejection; Humans; Hyperlipidemias; Hypertension

1999
Benefits of mycophenolate mofetil in cardiac transplant recipients with cyclosporine-induced nephropathy.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Azathioprine; Cardiomyopathy, Dilated; Coronary Disease; Cyclosporine; Female; Graft Rejection; Hear

1999
High incidence of post-transplant diabetes mellitus in Kuwait.
    Diabetes research and clinical practice, 2002, Volume: 55, Issue:2

    Topics: Adult; Azathioprine; Cause of Death; Coronary Disease; Cyclosporine; Diabetes Mellitus; Female; Graf

2002
Aspects of cyclosporine A toxicity in the development of coronary artery disease in transplant recipients.
    Transplantation proceedings, 2002, Volume: 34, Issue:4

    Topics: Adult; Azathioprine; Coronary Disease; Cyclosporine; Drug Therapy, Combination; Heart Transplantatio

2002
Cardiac transplantation: review of seven years' experience.
    Transplantation proceedings, 1976, Volume: 8, Issue:1

    Topics: Azathioprine; Coronary Disease; Graft Rejection; Heart Transplantation; Immunosuppression Therapy; P

1976
The present status of heart transplantation.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Feb-15, Volume: 49, Issue:7

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Coronary Disease; Echocardiography; Electrocardiography;

1975
Renal transplantation in the older age group.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:9

    Topics: Acute Kidney Injury; Age Factors; Aged; Azathioprine; Cadaver; Coronary Disease; Diabetes Complicati

1975
Relationship of immunosuppression and serum lipids to the development of coronary arterial disease in the transplanted heart.
    International journal of cardiology, 1991, Volume: 32, Issue:1

    Topics: Adult; Age Factors; Azathioprine; Cholesterol; Coronary Disease; Cyclosporins; Female; Heart Transpl

1991
Five-year experience with triple-drug immunosuppressive therapy in cardiac transplantation.
    Circulation, 1990, Volume: 82, Issue:5 Suppl

    Topics: Actuarial Analysis; Azathioprine; Coronary Disease; Cyclosporins; Drug Therapy, Combination; Female;

1990
Cardiac transplantation in the seventh decade of life.
    The American journal of cardiology, 1989, Jan-01, Volume: 63, Issue:1

    Topics: Actuarial Analysis; Aged; Azathioprine; Cardiomyopathy, Dilated; Coronary Disease; Cyclosporins; Fem

1989
Prevalence of accelerated coronary artery disease in heart transplant survivors. Comparison of cyclosporine and azathioprine regimens.
    Circulation, 1989, Volume: 80, Issue:5 Pt 2

    Topics: Azathioprine; Cohort Studies; Coronary Disease; Cyclosporins; Female; Graft Rejection; Heart Transpl

1989
Coronary artery disease in cardiac transplant patients receiving triple-drug immunosuppressive therapy.
    Circulation, 1989, Volume: 80, Issue:5 Pt 2

    Topics: Azathioprine; Coronary Disease; Cyclosporins; Female; Graft Rejection; Heart Transplantation; Histoc

1989
Are there indications for heterotopic heart transplantation today?
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Cardiomyopathies; Coronary Disease; Cyclospor

1987
Present expectations in cardiac transplantation.
    The Annals of thoracic surgery, 1987, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Azathioprine; Cardiomyopathies; Child; Child, Preschool; Coronary Disease; Cyclos

1987
Lipid mediators in organ transplantation: does cyclosporine accelerate coronary atherosclerosis?
    Transplantation proceedings, 1987, Volume: 19, Issue:4 Suppl 5

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Child; Coronary Disease; Cyclosporins; Female

1987
Renal transplantation in the older recipient.
    The Journal of urology, 1985, Volume: 134, Issue:2

    Topics: Age Factors; Antilymphocyte Serum; Azathioprine; Cadaver; Cardiomyopathies; Coronary Disease; Diabet

1985
Circulating antibody following cardiac transplantation in Ag-B-compatible rats.
    Transplantation, 1972, Volume: 13, Issue:6

    Topics: Animals; Antibody Formation; Azathioprine; Chromium Isotopes; Coronary Disease; Cytotoxicity Tests,

1972
Acute rejection in the long-term cardiac transplant survivor. Clinical diagnosis, treatment and significance.
    Circulation, 1974, Volume: 49, Issue:2

    Topics: Arteriosclerosis; Azathioprine; Biopsy; Coronary Disease; Cyclophosphamide; Electrocardiography; End

1974
Cardiac allograft pathology in Rhesus monkeys.
    American journal of physical anthropology, 1973, Volume: 38, Issue:2

    Topics: Animals; Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Coronary Disease; Coronary Vessels; G

1973
[Heart transplantation as a possibility in severe coronary insufficiency].
    Langenbecks Archiv fur Chirurgie, 1969, Volume: 325

    Topics: Adult; Aged; Antilymphocyte Serum; Azathioprine; Coronary Disease; Female; Heart Transplantation; He

1969
Roentgenologic aspects of cardiac transplantation. Postoperative pulmonary infections.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1971, Volume: 111, Issue:3

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathies; Coronary Disease; Female; Heart Transplantation; Huma

1971
Cardiac transplantation in man. II. Immunosuppressive therapy.
    The Journal of thoracic and cardiovascular surgery, 1969, Volume: 58, Issue:3

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Cardiomyopathies; Coronary Disease; Dactinomycin; Female;

1969
Myocardial changes and kidney transplantation. Lesions in patients receiving immunosuppressive therapy.
    Archives of pathology, 1969, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Arteriosclerosis; Autopsy; Azathioprine; Candida; Car

1969
[3 cases of allogenic heart graft in man].
    Archives des maladies du coeur et des vaisseaux, 1969, Volume: 62, Issue:6

    Topics: Adult; Angiocardiography; Azathioprine; Coronary Disease; Electrocardiography; Globulins; Heart Fail

1969