azathioprine has been researched along with Coronary Artery Disease in 6 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sirolimus was not found to be superior to mycophenolate mofetil in a randomized trial." | 2.44 | Proliferation signal inhibitors in cardiac transplantation. ( Gustafsson, F; Ross, HJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keogh, A | 2 |
| Richardson, M | 1 |
| Ruygrok, P | 1 |
| Spratt, P | 1 |
| Galbraith, A | 1 |
| O'Driscoll, G | 1 |
| Macdonald, P | 1 |
| Esmore, D | 1 |
| Muller, D | 1 |
| Faddy, S | 1 |
| Gustafsson, F | 1 |
| Ross, HJ | 1 |
| Aziz, TM | 1 |
| Sheldon, S | 1 |
| el-Gamel, A | 1 |
| Krysiak, P | 1 |
| Campbell, C | 1 |
| Rahman, A | 1 |
| Dyer, P | 1 |
| Yonan, N | 1 |
| Deiraniya, A | 1 |
| Sartori, TM | 1 |
| Maurizio, PG | 1 |
| Sara, P | 1 |
| Ugolino, L | 1 |
| Annalisa, A | 1 |
| Panagiotis, T | 1 |
| Massimo, F | 1 |
| Antonio, G | 1 |
| Carrier, M | 1 |
| White, M | 1 |
| Perrault, LP | 1 |
| Pelletier, GB | 1 |
| Pellerin, M | 1 |
| Robitaille, D | 1 |
| Pelletier, LC | 1 |
| Rose, ML | 1 |
| Smith, J | 1 |
| Dureau, G | 1 |
| Kobashigowa, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Vs Late Sirolimus-Initiation Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant Recipients[NCT01305395] | 0 participants (Actual) | Interventional | 2010-11-30 | Withdrawn (stopped due to Due in part, to reduced transplant volume and enrollment has been difficult.) | |||
| Assessment of Cardiac Allograft Vasculopathy (CAV) by Optical Coherence Tomography (OCT)[NCT02503566] | 150 participants (Anticipated) | Interventional | 2014-09-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Coronary Artery Disease
| Article | Year |
|---|---|
Proliferation signal inhibitors in cardiac transplantation.
Topics: Azathioprine; Calcineurin; Calcineurin Inhibitors; Cell Proliferation; Coronary Artery Disease; Dose | 2007 |
3 trials available for azathioprine and Coronary Artery Disease
| Article | Year |
|---|---|
Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Topics: Acute Disease; Adult; Azathioprine; Coronary Artery Disease; Creatinine; Follow-Up Studies; Graft Re | 2004 |
Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Topics: Acute Disease; Adult; Azathioprine; Coronary Artery Disease; Creatinine; Follow-Up Studies; Graft Re | 2004 |
Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Topics: Acute Disease; Adult; Azathioprine; Coronary Artery Disease; Creatinine; Follow-Up Studies; Graft Re | 2004 |
Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Topics: Acute Disease; Adult; Azathioprine; Coronary Artery Disease; Creatinine; Follow-Up Studies; Graft Re | 2004 |
A 10-year experience with intravenous thymoglobuline in induction of immunosuppression following heart transplantation.
Topics: Adult; Analysis of Variance; Antilymphocyte Serum; Azathioprine; Coronary Artery Disease; Cyclospori | 1999 |
Mycophenolate mofetil decreases antibody production after cardiac transplantation.
Topics: Antibody Formation; Azathioprine; Coronary Angiography; Coronary Artery Disease; Disease Progression | 2002 |
2 other studies available for azathioprine and Coronary Artery Disease
| Article | Year |
|---|---|
Implication of HLA mismatch in the clinical outcome of orthotopic heart transplantation.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Child; Coronary Artery Disease; Cyclosporine; | 1998 |
Relation between long-term steroid treatment after heart transplantation, hypofibrinolysis and myocardial microthrombi generation.
Topics: Azathioprine; Biopsy; Coronary Artery Disease; Cyclosporine; Drug Therapy, Combination; Female; Fibr | 1999 |