azathioprine has been researched along with Corneal Ulcer in 7 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a patient with a rare clinical presentation of marginal keratitis and pyoderma gangrenosum (PG) that responded to the steroid-sparing agent azathioprine." | 3.71 | Effective steroid-sparing treatment for peripheral ulcerative keratitis and pyoderma gangrenosum. ( Bower, KS; Brown, BA; Parker, CT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murillo, G | 1 |
| Ramírez, B | 1 |
| Romo, LA | 1 |
| Muñoz-Sanz, A | 1 |
| Hileeto, D | 1 |
| Calonge, M | 1 |
| Jifi-Bahlool, H | 1 |
| Saadeh, C | 1 |
| O'Connor, J | 1 |
| Sirois, D | 1 |
| Leigh, JE | 1 |
| Sollecito, TP | 1 |
| Brown, BA | 1 |
| Parker, CT | 1 |
| Bower, KS | 1 |
| Vivino, FB | 1 |
| Minerva, P | 1 |
| Huang, CH | 1 |
| Orlin, SE | 1 |
| Jayson, MI | 1 |
| Easty, DL | 1 |
| Fauci, AS | 1 |
| Wolff, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for azathioprine and Corneal Ulcer
| Article | Year |
|---|---|
Oculopalpebral borreliosis as an unusual manifestation of Lyme disease.
Topics: Adolescent; Antibodies, Bacterial; Azathioprine; Borrelia burgdorferi; Corneal Ulcer; Cyclosporine; | 2013 |
Peripheral ulcerative keratitis in the setting of rheumatoid arthritis: treatment with immunosuppressive therapy.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Corneal Ulcer; Cyclophosphamide; Drug Therapy, Combinatio | 1995 |
Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Corneal Ulcer; Cyclophosphamide | 2000 |
Effective steroid-sparing treatment for peripheral ulcerative keratitis and pyoderma gangrenosum.
Topics: Administration, Oral; Azathioprine; Biopsy; Cornea; Corneal Ulcer; Drug Therapy, Combination; Glucoc | 2001 |
Corneal melt as the initial presentation of primary Sjögren's syndrome.
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Corneal Stroma; Corneal Transplantation; Corneal Ulcer | 2001 |
Ulceration of the cornea in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Corneal Ulcer; Female; Humans; Male; Penicillamine | 1977 |
Wegener's granulomatosis: studies in eighteen patients and a review of the literature.
Topics: Adult; Aged; Azathioprine; Biopsy; Corneal Ulcer; Cyclophosphamide; Diagnosis, Differential; Ear Dis | 1973 |