azathioprine has been researched along with Connective Tissue Disease, Mixed in 27 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since there was no activity of the mixed connective tissue disease the methylprednisolone dosage was reduced and the administration of azathioprine was ceased." | 2.39 | [Chronic recurrent subileus due to Strongyloides stercoralis infection under immunosuppressive therapy]. ( Back, W; Birck, R; Braun, C; Gottstein, T; Gretz, N; Manegold, BC; Rohmeiss, P; Strauch, M, 1996) |
| "Mixed connective tissue disorder (MCTD) with predominant polymyositis and neuropsychiatric manifestations was diagnosed as the patient had anti-RNP positive with significantly raised muscle enzymes." | 1.40 | Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder. ( Kiani, IG; Qureshi, SH; Shah, F, 2014) |
| "In patients with systemic sclerosis or mixed connective tissue disease (MCTD) acral ulcers are considered as frequent manifestations that may lead to amputation and loss of function, respectively, as a result of secondary Raynaud's phenomenon." | 1.36 | [Treatment options of acral ulcers in MCTD]. ( Girndt, M; Herink, AK; Keysser, G; Köthe, L, 2010) |
| "Mixed Connective Tissue Disorder with Castleman's Disease is a rare association; the patient presenting with varied and interesting manifestations." | 1.36 | Mixed connective tissue disorder and Castleman's disease. ( Boorugu, HK; Chrispal, A; Thomas, EM; Vasuki, Z, 2010) |
| "This report describes a patient with mixed connective tissue disease (MCTD) and trigeminal neuralgia (TN)." | 1.33 | Trigeminal neuralgia as the first manifestation of mixed connective tissue disorder. ( Barland, P; Hojaili, B, 2006) |
| "A diagnosis of mixed connective tissue disease (Sharp-syndrome) was established." | 1.30 | [A patient with mixed collagen disease, antiphospholipid syndrome and Sjögren syndrome]. ( Hartmann, F; Kranzhöfer, N; Lindemuth, R; Zuber, M, 1998) |
| "We report an unusual case of MCTD with recurrent optic neuropathy and transverse myelopathy suggestive of a relapsing-remitting demyelinating disorder." | 1.29 | Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis. ( Baum, K; Flechtner, KM, 1994) |
| "Azathioprine was very effective against the interstitial pneumonia in this case, but general conclusions about the most effective type of immunosuppressive agent and the timing of its administration must await the results of further study." | 1.29 | [Interstitial pneumonia associated with mixed connective tissue disease--marked improvement with azathioprine]. ( Aoki, S; Iwase, A; Kitamura, S; Matsuoka, R; Nagayama, T; Sakamoto, K; Shimizu, K; Suzuki, M, 1996) |
| "We describe a patient with mixed connective tissue disease (MCTD), who developed pure red cell aplasia which responded favorably during treatment with corticosteroids." | 1.28 | Pure red cell aplasia in mixed connective tissue disease. ( Jäntti, J; Julkunen, H; Pettersson, T, 1989) |
| "A case of transverse myelitis in a 16-year-old woman with mixed connective tissue disease is described." | 1.27 | Transverse myelitis in mixed connective tissue disease. ( Boesen, F; Bonen, H; Pedersen, C, 1987) |
| "A patient with discoid lupus erythematosus is reported which turned into a mixed connective tissue disease (MCTD) within five months." | 1.26 | [Development of "mixed connective tissue disease" (MCTD) from discoid lupus erythematosus]. ( Bauer, R; Orfanos, CE; Schultz-Ehrenburg, U, 1981) |
| "All but one of 28 patients with mixed connective tissue disease (MCTD) who were studied prospectively had arthralgia, and 15 of them had noticed joint swelling." | 1.26 | Articular manifestations of mixed connective tissue disease. ( Alarcón-Segovia, D; Hernández-Ortíz, J; Ramos-Niembro, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manohar, H | 1 |
| Kuppili, PP | 1 |
| Menon, V | 1 |
| Postlethwaite, B | 1 |
| Wynn, HG | 1 |
| Pattanaik, D | 1 |
| Ost, S | 1 |
| MacDonald, CB | 1 |
| Walton, RC | 1 |
| Kim, S | 1 |
| Myers, LK | 1 |
| Brown Lobbins, M | 1 |
| Kiani, IG | 1 |
| Qureshi, SH | 1 |
| Shah, F | 1 |
| Zold, E | 1 |
| Bodolay, E | 1 |
| Dezső, B | 1 |
| Soos, G | 1 |
| Nakken, B | 1 |
| Szodoray, P | 1 |
| Herink, AK | 1 |
| Köthe, L | 1 |
| Girndt, M | 1 |
| Keysser, G | 1 |
| Chrispal, A | 1 |
| Vasuki, Z | 1 |
| Thomas, EM | 1 |
| Boorugu, HK | 1 |
| Chao, CT | 1 |
| Lai, CY | 1 |
| Chang, PL | 1 |
| Wu, HS | 1 |
| Wu, VC | 1 |
| Wang, WJ | 1 |
| Murakami, M | 1 |
| Shimane, K | 1 |
| Takahashi, H | 1 |
| Tomiyama, J | 1 |
| Nagashima, M | 1 |
| Nagashima, T | 1 |
| Masuyama, J | 1 |
| Okubo, H | 1 |
| Minota, S | 1 |
| Bhinder, S | 1 |
| Harbour, K | 1 |
| Majithia, V | 1 |
| Hojaili, B | 1 |
| Barland, P | 1 |
| Mosca, M | 1 |
| Tani, C | 1 |
| Bombardieri, S | 1 |
| Bauer, R | 1 |
| Schultz-Ehrenburg, U | 1 |
| Orfanos, CE | 1 |
| Anderson, IF | 1 |
| Anderson, R | 1 |
| Mok, CC | 1 |
| Lau, CS | 1 |
| Segawa, F | 1 |
| Shimizu, Y | 1 |
| Saito, E | 1 |
| Kinoshita, M | 1 |
| Flechtner, KM | 1 |
| Baum, K | 1 |
| Birck, R | 1 |
| Braun, C | 1 |
| Back, W | 1 |
| Gottstein, T | 1 |
| Rohmeiss, P | 1 |
| Manegold, BC | 1 |
| Strauch, M | 1 |
| Gretz, N | 1 |
| Suzuki, M | 1 |
| Shimizu, K | 1 |
| Sakamoto, K | 1 |
| Iwase, A | 1 |
| Aoki, S | 1 |
| Matsuoka, R | 1 |
| Nagayama, T | 1 |
| Kitamura, S | 1 |
| Zuber, M | 1 |
| Kranzhöfer, N | 1 |
| Lindemuth, R | 1 |
| Hartmann, F | 1 |
| Sofat, N | 1 |
| Houghton, J | 1 |
| McHale, J | 1 |
| Higgens, CS | 1 |
| Cacoub, P | 1 |
| Sbaï, A | 1 |
| Toan, SV | 1 |
| Bellanger, J | 1 |
| Hoang, C | 1 |
| Godeau, P | 1 |
| Piette, JC | 1 |
| Loddenkemper, K | 1 |
| Perka, C | 1 |
| Burmester, GR | 1 |
| Buttgereit, F | 1 |
| Ramos-Niembro, F | 1 |
| Alarcón-Segovia, D | 1 |
| Hernández-Ortíz, J | 1 |
| Julkunen, H | 1 |
| Jäntti, J | 1 |
| Pettersson, T | 1 |
| Hendra, TJ | 1 |
| Pedersen, C | 1 |
| Bonen, H | 1 |
| Boesen, F | 1 |
3 reviews available for azathioprine and Connective Tissue Disease, Mixed
| Article | Year |
|---|---|
Transverse myelitis, a rare neurological manifestation of mixed connective tissue disease--a case report and a review of literature.
Topics: Aged; Azathioprine; Female; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Magnetic | 2007 |
A case of undifferentiated connective tissue disease: is it a distinct clinical entity?
Topics: Adrenal Cortex Hormones; Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Diagnosis, Differ | 2008 |
[Chronic recurrent subileus due to Strongyloides stercoralis infection under immunosuppressive therapy].
Topics: Adult; Animals; Azathioprine; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combination; D | 1996 |
24 other studies available for azathioprine and Connective Tissue Disease, Mixed
| Article | Year |
|---|---|
Major depression: An under reported neuropsychiatric manifestation of Mixed Connective Tissue Disease.
Topics: Antidepressive Agents, Second-Generation; Antimetabolites; Azathioprine; Citalopram; Depressive Diso | 2017 |
Retinal Vasculitis and Choroidopathy in Pediatric-Onset Mixed Connective Tissue Disease.
Topics: Adolescent; Antibodies, Antinuclear; Azathioprine; Choroid Diseases; Cyclophosphamide; Diagnostic Te | 2017 |
Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder.
Topics: Adult; Antibodies, Antinuclear; Anticonvulsants; Antidepressive Agents, Second-Generation; Azathiopr | 2014 |
Mixed connective tissue disease associated with autoimmune hepatitis and pulmonary fibrosis.
Topics: Adult; Azathioprine; Biopsy; Bronchoscopy; Disease Progression; Female; Hepatitis, Autoimmune; Human | 2014 |
[Treatment options of acral ulcers in MCTD].
Topics: Adult; Amides; Analgesia, Patient-Controlled; Angiography, Digital Subtraction; Autonomic Nerve Bloc | 2010 |
Mixed connective tissue disorder and Castleman's disease.
Topics: Adolescent; Azathioprine; Biopsy; Castleman Disease; Female; Glomerulonephritis, Membranoproliferati | 2010 |
Mixed connective tissue disease with protein-losing enteropathy: discussion of the treatment strategy.
Topics: Administration, Oral; Adult; Antirheumatic Agents; Azathioprine; Comorbidity; Cyclophosphamide; Drug | 2011 |
ANCA-associated vasculitis with dual ANCA positivity in coexistence with mixed connective tissue disease.
Topics: Adult; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytopl | 2013 |
Marked dilatation of pulmonary arteries in mixed connective tissue disease.
Topics: Activities of Daily Living; Azathioprine; Blood Pressure; Digoxin; Dilatation, Pathologic; Drug Ther | 2005 |
Trigeminal neuralgia as the first manifestation of mixed connective tissue disorder.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Azathioprine; Diagnosis, Differential; Female; Human | 2006 |
[Development of "mixed connective tissue disease" (MCTD) from discoid lupus erythematosus].
Topics: Antibodies, Antinuclear; Azathioprine; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; Mi | 1981 |
A case of mixed connective tissue disease.
Topics: Adult; Azathioprine; Female; Humans; Mixed Connective Tissue Disease; Prednisone | 1981 |
Transverse myelopathy complicating mixed connective tissue disease.
Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; | 1995 |
Behçet's disease induced by interferon therapy for chronic myelogenous leukemia.
Topics: Azathioprine; Behcet Syndrome; Female; Humans; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR | 1995 |
Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis.
Topics: Adult; Azathioprine; Female; Humans; Magnetic Resonance Imaging; Mixed Connective Tissue Disease; My | 1994 |
[Interstitial pneumonia associated with mixed connective tissue disease--marked improvement with azathioprine].
Topics: Azathioprine; Drug Administration Schedule; Humans; Immunosuppressive Agents; Lung Diseases, Interst | 1996 |
[A patient with mixed collagen disease, antiphospholipid syndrome and Sjögren syndrome].
Topics: Adult; Antiphospholipid Syndrome; Aspirin; Azathioprine; Biopsy; Diagnosis, Differential; Drug Thera | 1998 |
Azathioprine hypersensitivity.
Topics: Adult; Antirheumatic Agents; Azathioprine; Drug Hypersensitivity; Drug Therapy, Combination; Female; | 2001 |
[Collagenous colitis. A study of 11 cases].
Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Anemia; Anti-Inflammatory Agents; Anti-Inflammat | 2001 |
Coincidence of asymptomatic avascular necrosis and fracture of the femoral neck: a rare combination of glucocorticoid induced side effects.
Topics: Azathioprine; Bone Density; Female; Femoral Neck Fractures; Femur Head Necrosis; Humans; Immunosuppr | 2002 |
Articular manifestations of mixed connective tissue disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Azathioprine; Child; Female; Huma | 1979 |
Pure red cell aplasia in mixed connective tissue disease.
Topics: Adult; Azathioprine; Female; Humans; Methylprednisolone; Mixed Connective Tissue Disease; Red-Cell A | 1989 |
Failure of steroid and immunosuppressant therapy to halt progression of mixed connective tissue disease.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Mixed Connective Tissue Disease; Pre | 1988 |
Transverse myelitis in mixed connective tissue disease.
Topics: Adolescent; Azathioprine; Drug Therapy, Combination; Female; Humans; Mixed Connective Tissue Disease | 1987 |