azathioprine has been researched along with Complications of Diabetes Mellitus in 28 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infectious complications within 1 year of cadaveric kidney transplantation were compared in 45 patients treated with azathioprine, prednisone, and antilymphocyte globulin and 38 patients treated with cyclosporine and prednisone." | 7.67 | Infectious complications with the use of cyclosporine versus azathioprine after cadaveric kidney transplantation. ( Hammer, SM; Monaco, AP; Shaffer, D, 1987) |
| "Laboratory examination revealed acute disseminated intravascular coagulation and lactacidaemia." | 5.25 | [Lactacidaemia and disseminated intravascular coagulation associated with phenformin medication (author's transl)]. ( Dienstl, F; Holzknecht, F; Hörtnagl, H; Kunz, F; Lederer, B, 1975) |
| "Nineteen of 224 renal allograft recipients who were prospectively randomized to receive either cyclosporine (n = 117) or azathioprine sodium-antilymphocyte globulin (n = 107) for immunosuppression suffered from one period of pneumonia (14 azathioprine and five cyclosporine recipients); two recipients of azathioprine had two episodes." | 5.06 | Pulmonary infections. The Minnesota randomized prospective trial of cyclosporine vs azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients. ( Chatterjee, SN; Fryd, DS; Hesse, UJ; Najarian, JS; Simmons, RL; Sutherland, DE, 1986) |
| " In univariate analysis, older age at PM/DM onset, anemia, thrombocytopenia, leukopenia, diabetes mellitus, ILD, cancer, and non-use of azathioprine were associated with higher mortality (p = 0." | 3.77 | Survival analysis of patients with dermatomyositis and polymyositis: analysis of 192 Chinese cases. ( Chang, HC; Chen, IJ; Ho, HH; Kuo, CF; Luo, SF; See, LC; Shen, YM; Wu, YJ; Yu, KH, 2011) |
| "Diabetes mellitus (DM) has been considered a relative contraindication to heart transplantation (HTx) because of possible increased infection rates and worsening DM with prednisone immunosuppression." | 3.69 | Mid-term results of heart transplantation in diabetic patients. ( Bianco, R; Boffa, GM; Caforio, AL; Casarotto, D; Casula, R; Gambino, A; Grassi, G; Livi, U; Milano, A; Thiene, G, 1994) |
| "Infectious complications within 1 year of cadaveric kidney transplantation were compared in 45 patients treated with azathioprine, prednisone, and antilymphocyte globulin and 38 patients treated with cyclosporine and prednisone." | 3.67 | Infectious complications with the use of cyclosporine versus azathioprine after cadaveric kidney transplantation. ( Hammer, SM; Monaco, AP; Shaffer, D, 1987) |
| "Laboratory examination revealed acute disseminated intravascular coagulation and lactacidaemia." | 1.25 | [Lactacidaemia and disseminated intravascular coagulation associated with phenformin medication (author's transl)]. ( Dienstl, F; Holzknecht, F; Hörtnagl, H; Kunz, F; Lederer, B, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (75.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 3 (10.71) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, HJ | 1 |
| Lai, CC | 1 |
| Lai, FJ | 1 |
| Li, SY | 1 |
| Liang, HY | 1 |
| Hsueh, PR | 1 |
| Yu, KH | 1 |
| Wu, YJ | 1 |
| Kuo, CF | 1 |
| See, LC | 1 |
| Shen, YM | 1 |
| Chang, HC | 1 |
| Luo, SF | 1 |
| Ho, HH | 1 |
| Chen, IJ | 1 |
| Canet, S | 1 |
| Garrigue, V | 1 |
| Bismuth, J | 1 |
| Chong, G | 1 |
| Lesnik, A | 1 |
| Taourel, P | 1 |
| Mourad, G | 1 |
| Hong, MKh | 1 |
| Angus, PW | 1 |
| Jones, RM | 1 |
| Vaughan, RB | 1 |
| Gow, PJ | 1 |
| David, KM | 1 |
| Morris, JA | 1 |
| Steffen, BJ | 1 |
| Chi-Burris, KS | 1 |
| Gotz, VP | 1 |
| Gordon, RD | 1 |
| Gref, C | 1 |
| Maaz, E | 1 |
| Livi, U | 1 |
| Caforio, AL | 1 |
| Grassi, G | 1 |
| Boffa, GM | 1 |
| Gambino, A | 1 |
| Milano, A | 1 |
| Bianco, R | 1 |
| Casula, R | 1 |
| Thiene, G | 1 |
| Casarotto, D | 1 |
| Gifford, RR | 1 |
| Schmidtke, JR | 1 |
| Sutherland, DE | 4 |
| Simmons, RL | 5 |
| Najarian, JS | 5 |
| Delmonico, FL | 1 |
| Cosimi, AB | 1 |
| Russell, PS | 1 |
| Kunz, F | 1 |
| Dienstl, F | 1 |
| Hörtnagl, H | 1 |
| Holzknecht, F | 1 |
| Lederer, B | 1 |
| Rancourt, J | 1 |
| Lassonde, M | 1 |
| Bry, W | 1 |
| Warvariv, V | 1 |
| Bohannon, L | 1 |
| Feduska, N | 1 |
| Straube, B | 1 |
| Collins, G | 1 |
| Levin, B | 1 |
| Shaffer, D | 1 |
| Hammer, SM | 1 |
| Monaco, AP | 1 |
| Hesse, UJ | 1 |
| Fryd, DS | 3 |
| Chatterjee, SN | 1 |
| Strand, M | 1 |
| Canafax, DM | 2 |
| Ascher, NL | 2 |
| Payne, WD | 2 |
| Glass, NR | 1 |
| Miller, DT | 1 |
| Sollinger, HW | 1 |
| Belzer, FO | 1 |
| Strand, MH | 1 |
| Jordan, ML | 1 |
| Novick, AC | 1 |
| Steinmuller, D | 1 |
| Braun, W | 1 |
| Buszta, C | 1 |
| Mintz, D | 1 |
| Goormastic, M | 1 |
| Streem, S | 1 |
| Ballinger, WF | 1 |
| Lacy, PE | 1 |
| Braun, WE | 1 |
| Manning, RF | 1 |
| Henriksen, AI | 1 |
| Kjellstrand, CM | 1 |
| Kountz, SL | 1 |
| Neuberg, R | 1 |
| Spenney, JG | 1 |
| Eure, CA | 1 |
| Kreisberg, RA | 1 |
| Marks, MI | 1 |
| Salomon, MI | 1 |
| Mandel, EH | 1 |
| Gallo, G | 1 |
| Hokkanen, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression[NCT00006505] | Phase 2 | 6 participants (Actual) | Interventional | 2000-11-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[Nocardiosis--is it frequently observed after the introduction of new immunosuppressive agents in renal transplantation?].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Com | 2004 |
Kidney transplantation for patients with diabetes mellitus.
Topics: Acute Kidney Injury; Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Diabetes Complications; | 1974 |
Clinical renal transplantation.
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; Cadaver; Cyclophosphamide; Diabetes Com | 1974 |
5 trials available for azathioprine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Cadaveric renal transplant without prophylactic prednisone therapy.
Topics: Antilymphocyte Serum; Azathioprine; Cadaver; Cyclosporins; Diabetes Complications; Graft Survival; H | 1991 |
A randomized clinical trial of cyclosporine in cadaveric renal transplantation. Analysis at three years.
Topics: Acidosis, Renal Tubular; Adolescent; Adult; Age Factors; Antilymphocyte Serum; Azathioprine; Cadaver | 1986 |
Pulmonary infections. The Minnesota randomized prospective trial of cyclosporine vs azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Diabetes Complica | 1986 |
A single institution, randomized, prospective trial of cyclosporin versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
Topics: Adolescent; Adult; Antilymphocyte Serum; Aspartate Aminotransferases; Azathioprine; Clinical Trials | 1985 |
Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Bacterial Infections; Clinical Trials as Topi | 1985 |
20 other studies available for azathioprine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Emergence of multidrug-resistant Candida auris in Taiwan.
Topics: Azathioprine; Candida; Candidiasis; Dermatomycoses; Diabetes Complications; Drug Resistance, Multipl | 2019 |
Survival analysis of patients with dermatomyositis and polymyositis: analysis of 192 Chinese cases.
Topics: Adult; Aged; Antirheumatic Agents; Azathioprine; Dermatomyositis; Diabetes Complications; Female; Fo | 2011 |
Predictors of improvement in renal function after calcineurin inhibitor withdrawal for post-liver transplant renal dysfunction.
Topics: Azathioprine; Calcineurin Inhibitors; Creatinine; Diabetes Complications; Enzyme Inhibitors; Female; | 2005 |
Mycophenolate mofetil vs. azathioprine is associated with decreased acute rejection, late acute rejection, and risk for cardiovascular death in renal transplant recipients with pre-transplant diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Black People; Cause of Death; Diabetes Com | 2005 |
[Pathogenesis and prognosis of acute hepatitis in diabetics].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Azathioprine; Chronic Disease; Dia | 1980 |
Mid-term results of heart transplantation in diabetic patients.
Topics: Actuarial Analysis; Adult; Azathioprine; Cardiac Catheterization; Coronary Angiography; Cyclosporins | 1994 |
Improved renal allograft survival with selected HLA antigen matching.
Topics: Antilymphocyte Serum; Azathioprine; Diabetes Complications; Follow-Up Studies; Graft Rejection; Graf | 1979 |
Renal transplantation in the older age group.
Topics: Acute Kidney Injury; Age Factors; Aged; Azathioprine; Cadaver; Coronary Disease; Diabetes Complicati | 1975 |
[Lactacidaemia and disseminated intravascular coagulation associated with phenformin medication (author's transl)].
Topics: Acidosis; Azathioprine; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Disseminated Int | 1975 |
[Pemphigus and azathioprine].
Topics: Aged; Azathioprine; Diabetes Complications; Humans; Male; Pemphigus | 1975 |
Infectious complications with the use of cyclosporine versus azathioprine after cadaveric kidney transplantation.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cadaver; Cyclosporins; Diabetes Complications; Drug Thera | 1987 |
A four-year experience with donor blood transfusion protocols for living-donor renal transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Blood Transfusion; Child; Creatinine; Diabetes Complications; | 1985 |
Renal transplantation in the older recipient.
Topics: Age Factors; Antilymphocyte Serum; Azathioprine; Cadaver; Cardiomyopathies; Coronary Disease; Diabet | 1985 |
Transplantation of intact pancreatic islets in rats.
Topics: Animals; Azathioprine; Blood Glucose; Cataract; Diabetes Complications; Diabetes Mellitus; Glycosuri | 1972 |
Renal transplantation--the changing scene.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Creatinine; Cyclophosphamide; Diabetes Complications; G | 1972 |
Immunosuppression and plasmocytoma of the cervix.
Topics: Adult; Azathioprine; Diabetes Complications; Female; Furosemide; Humans; Immunosuppression Therapy; | 1974 |
Hyperglycemic, hyperosmolar, nonketoacidotic diabetes. A complication of steroid and immunosupressive therapy.
Topics: Adult; Azathioprine; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Diagno | 1969 |
Iatrogenic pneumaturia.
Topics: Azathioprine; Bacteriuria; Cryptococcus; Diabetes Complications; Diabetes Mellitus; Escherichia coli | 1971 |
Degos' disease associated with a "spontaneous cure" of diabetes.
Topics: Azathioprine; Diabetes Complications; Diabetes Mellitus; Female; Gastrointestinal Diseases; Glucocor | 1971 |
Myasthenia gravis. A clinical analysis of the total material from Finland with special reference to endocrinological and neurological disorders.
Topics: Age Factors; Ambenonium Chloride; Azathioprine; Cortisone; Diabetes Complications; Disability Evalua | 1969 |