azathioprine has been researched along with Common Variable Immunodeficiency in 14 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Common Variable Immunodeficiency: Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Granulomatous and lymphocytic interstitial lung disease (GLILD) is a life-threatening complication in patients with common variable immunodeficiency (CVID), but the optimal treatment is unknown." | 1.62 | Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency. ( Barbeau, J; Baruah, D; Bausch-Jurken, M; Busalacchi, A; Chen, S; Cool, CD; Feng, M; Hammelev, E; Hintermeyer, MK; Rao, N; Routes, JM; Rymaszewski, A; Simpson, PM; Sosa-Lozano, LA; Verbsky, JW; Woodliff, J, 2021) |
| "An exacerbation of the myelitis, retinitis, encephalitis and colitis was observed and a cytomegalovirus infection diagnosed." | 1.31 | CMV complications in common variable immunodeficiency. ( Schmidt, RE; Werwitzke, S; Witte, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Verbsky, JW | 2 |
| Hintermeyer, MK | 2 |
| Simpson, PM | 2 |
| Feng, M | 1 |
| Barbeau, J | 1 |
| Rao, N | 1 |
| Cool, CD | 1 |
| Sosa-Lozano, LA | 1 |
| Baruah, D | 1 |
| Hammelev, E | 1 |
| Busalacchi, A | 1 |
| Rymaszewski, A | 1 |
| Woodliff, J | 1 |
| Chen, S | 1 |
| Bausch-Jurken, M | 1 |
| Routes, JM | 2 |
| Moctezuma, SI | 1 |
| Panizo, CM | 1 |
| Landecho, MF | 1 |
| Lougaris, V | 1 |
| Baronio, M | 1 |
| Gazzurelli, L | 1 |
| Lorenzini, T | 1 |
| Fuoti, M | 1 |
| Moratto, D | 1 |
| Bozzola, A | 1 |
| Ricci, C | 1 |
| Bondioni, MP | 1 |
| Ravelli, A | 1 |
| Villanacci, V | 1 |
| Plebani, A | 1 |
| Choi, SW | 1 |
| Seo, KW | 1 |
| Oh, JS | 1 |
| Lee, JS | 1 |
| Cha, HJ | 1 |
| Trigo Salado, C | 1 |
| Leo Carnerero, E | 1 |
| Pizarro Moreno, Á | 1 |
| de la Cruz Ramírez, MD | 1 |
| Araujo Miguez, Á | 1 |
| Herrera Justiniano, JM | 1 |
| Márquez Galán, JL | 1 |
| Mock, JR | 1 |
| Kolb, TM | 1 |
| Illei, PB | 1 |
| Yang, SC | 1 |
| Lederman, HM | 1 |
| Merlo, CA | 1 |
| Pathria, M | 1 |
| Urbine, D | 1 |
| Zumberg, MS | 1 |
| Guarderas, J | 1 |
| Chase, NM | 1 |
| Waukau, JK | 1 |
| Tomita-Mitchell, A | 1 |
| Casper, JT | 1 |
| Singh, S | 1 |
| Shahir, KS | 1 |
| Tisol, WB | 1 |
| Nugent, ML | 1 |
| Rao, RN | 1 |
| Mackinnon, AC | 1 |
| Goodman, LR | 1 |
| Medlicott, SA | 1 |
| Coderre, S | 1 |
| Horne, G | 1 |
| Panaccione, R | 1 |
| Miller, BW | 1 |
| Brennan, DC | 1 |
| Korenblat, PE | 1 |
| Goss, JA | 1 |
| Flye, MW | 1 |
| Sacco, O | 1 |
| Fregonese, B | 1 |
| Picco, P | 1 |
| Faraci, M | 1 |
| Facchetti, P | 1 |
| Pistoia, V | 1 |
| Rossi, GA | 1 |
| Crawford, WW | 1 |
| Yusin, JS | 1 |
| Klaustermeyer, WB | 1 |
| Witte, T | 1 |
| Werwitzke, S | 1 |
| Schmidt, RE | 1 |
| Gause, A | 1 |
| Inderrieden, DC | 1 |
| Laas, R | 1 |
| Arlt, AC | 1 |
| Gross, WL | 1 |
2 reviews available for azathioprine and Common Variable Immunodeficiency
| Article | Year |
|---|---|
Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency.
Topics: Azathioprine; Common Variable Immunodeficiency; Cough; Dyspnea; Female; Humans; Immunoglobulins, Int | 2016 |
Common variable immunodeficiency in a renal transplant patient with severe recurrent bacterial infection: a case report and review of the literature.
Topics: Adolescent; Azathioprine; Common Variable Immunodeficiency; Humans; Immunoglobulins, Intravenous; Im | 1995 |
1 trial available for azathioprine and Common Variable Immunodeficiency
| Article | Year |
|---|---|
Use of combination chemotherapy for treatment of granulomatous and lymphocytic interstitial lung disease (GLILD) in patients with common variable immunodeficiency (CVID).
Topics: Administration, Oral; Adolescent; Adult; Antibodies, Monoclonal, Murine-Derived; Azathioprine; B-Lym | 2013 |
11 other studies available for azathioprine and Common Variable Immunodeficiency
| Article | Year |
|---|---|
Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency.
Topics: Adolescent; Adult; Azathioprine; Common Variable Immunodeficiency; Enzyme Inhibitors; Female; Humans | 2021 |
Common variable immunodeficiency-associated granulomatous and lymphocytic interstitial lung disease successfully treated with a combination regimen of rituximab and azathioprine.
Topics: Azathioprine; Common Variable Immunodeficiency; Drug Therapy, Combination; Female; Humans; Immunosup | 2017 |
A de novo monoallelic CTLA-4 deletion causing pediatric onset CVID with recurrent autoimmune cytopenias and severe enteropathy.
Topics: Adalimumab; Adolescent; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Autoimmune Diseases | 2018 |
Successful treatment of enteropathy associated with common variable immunodeficiency.
Topics: Adrenal Cortex Hormones; Azathioprine; Biopsy; Chronic Disease; Colonoscopy; Common Variable Immunod | 2014 |
[Treatment with immunosupressants in a patient with Crohn's disease and common variable immunodeficiency].
Topics: Adrenal Cortex Hormones; Azathioprine; Campylobacter Infections; Common Variable Immunodeficiency; C | 2015 |
Bronchus-associated Lymphoid Tissue in Kabuki Syndrome with Associated Hyper-IgM Syndrome/Common Variable Immunodeficiency.
Topics: Abnormalities, Multiple; Adult; Antineoplastic Agents, Immunological; Azathioprine; Biopsy; Bronchi; | 2016 |
Multimodal immunosuppressant therapy in steroid-refractory common variable immunodeficiency sprue: a case report complicating cytomegalovirus infection.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Antiviral Agents; Azathioprine; Celiac Disease; Com | 2006 |
Common variable immunodeficiency presenting in a girl as lung infiltrates and mediastinal adenopathies leading to severe "superior vena caval" syndrome.
Topics: Anti-Inflammatory Agents; Azathioprine; Child; Common Variable Immunodeficiency; Diagnosis, Differen | 1996 |
Nonsurgical regression of thymoma following corticosteroid/azathioprine therapy.
Topics: Adrenal Cortex Hormones; Agammaglobulinemia; Azathioprine; Common Variable Immunodeficiency; Humans; | 1999 |
CMV complications in common variable immunodeficiency.
Topics: Adult; Antiviral Agents; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lym | 2000 |
Common variable immunodeficiency (CVID) and inclusion body myositis (IBM).
Topics: Adult; Arthralgia; Azathioprine; Common Variable Immunodeficiency; Fatigue; gamma-Globulins; Humans; | 2000 |