azathioprine has been researched along with Colorectal Neoplasms in 32 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year-old woman was treated for colorectal diffuse large B-cell lymphoma (DLBCL) after a prolonged treatment period of azathioprine (AZA) and infliximab (IFX) for Crohn's disease (CD)." | 7.96 | Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine. ( Daikuhara, S; Hirayama, A; Sato, K; Suga, T; Tanaka, E; Uehara, T, 2020) |
| "A 52-year-old woman was treated for colorectal diffuse large B-cell lymphoma (DLBCL) after a prolonged treatment period of azathioprine (AZA) and infliximab (IFX) for Crohn's disease (CD)." | 3.96 | Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine. ( Daikuhara, S; Hirayama, A; Sato, K; Suga, T; Tanaka, E; Uehara, T, 2020) |
| "UC related colorectal cancer develop in an unpredictable manner with respect to disease duration and site questioning the validity of strict screening protocol." | 2.53 | Inflammatory bowel disease in India - Past, present and future. ( Ray, G, 2016) |
| "An increased risk of colorectal cancer (CRC) is present also after LT in IBD patients with primary sclerosing cholangitis (PSC)." | 2.50 | Clinical management of inflammatory bowel disease in the organ recipient. ( Indriolo, A; Ravelli, P, 2014) |
| "Primary sclerosing cholangitis is a chronic progressive disorder which involves the medium size and large ducts in the intrahepatic and extrahepatic biliary tree." | 2.49 | Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature. ( Chaparro, M; Gisbert, JP; Guijarro, M; López, C; Moreno-Otero, R; Trapero-Marugán, M, 2013) |
| "Ulcerative colitis is a chronic inflammatory bowel disease." | 2.42 | [Management of ulcerative colitis]. ( Kullak-Ublick, GA; Rammert, Ch, 2003) |
| "Kaposi sarcoma is an unusual tumor associated to a human herpes virus-8 infection involving the skin or internal organs." | 1.46 | Iatrogenic colorectal Kaposi's sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient. ( Amouri, A; Ayedi, L; Boudabous, M; Boudaouara, T; Chtourou, L; Grati, A; Mnif, L; Mzali, R; Rejab, H; Tahri, N, 2017) |
| "No significant risk for other intestinal cancers was found, especially for small bowel carcinoma." | 1.43 | Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016) |
| "Kaposi sarcoma is a mesenchymal tumor associated to a human herpes virus-8." | 1.39 | Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient. ( Azzouz, MM; Bouassida, M; Chalbi, E; Ezzine, H; Hamzaoui, L; Kilani, H; Mahmoudi, M; Sassi, S; Siai, K; Touinsi, H, 2013) |
| "There is an increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD)." | 1.33 | Distal adenomatous polyps are rare in patients with inflammatory bowel disease. ( Dixon, A; Hart, A; Robinson, R; Wurm, P, 2006) |
| "The risk of colorectal cancer was not increased, either in the total group of patients or in patients with colonic Crohn's disease exclusively (standardized morbidity ratio, 1." | 1.32 | Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark. ( Binder, V; Jess, T; Langholz, E; Munkholm, P; Winther, KV, 2004) |
| "Azathioprine was given to 626 of 2204 patients (855 with Crohn's disease and 1349 with ulcerative colitis)." | 1.31 | Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine. ( Fraser, AG; Jewell, DP; Orchard, TR; Robinson, EM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, K | 1 |
| Ohe, R | 1 |
| Kabasawa, T | 1 |
| Aung, NY | 1 |
| Yano, M | 1 |
| Katsumi, S | 1 |
| Yanagiya, R | 1 |
| Yamamoto, M | 1 |
| Toubai, T | 1 |
| Ishizawa, K | 1 |
| Yamakawa, M | 1 |
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Walinjkar, S | 1 |
| Kumar, A | 1 |
| Sharma, P | 1 |
| Gupta, P | 1 |
| Bansal, N | 1 |
| Singla, V | 1 |
| Anikhindi, SA | 1 |
| Arora, A | 1 |
| Laharie, D | 1 |
| Riviere, P | 1 |
| Chtourou, L | 1 |
| Ayedi, L | 1 |
| Rejab, H | 1 |
| Boudabous, M | 1 |
| Mnif, L | 1 |
| Grati, A | 1 |
| Boudaouara, T | 1 |
| Mzali, R | 1 |
| Amouri, A | 1 |
| Tahri, N | 1 |
| Sato, K | 1 |
| Suga, T | 1 |
| Hirayama, A | 1 |
| Daikuhara, S | 1 |
| Uehara, T | 1 |
| Tanaka, E | 1 |
| Gong, J | 1 |
| Zhu, L | 1 |
| Guo, Z | 1 |
| Li, Y | 1 |
| Zhu, W | 1 |
| Li, N | 1 |
| Li, J | 1 |
| Galatola, M | 1 |
| Miele, E | 1 |
| Strisciuglio, C | 1 |
| Paparo, L | 1 |
| Rega, D | 1 |
| Delrio, P | 1 |
| Duraturo, F | 1 |
| Martinelli, M | 1 |
| Rossi, GB | 1 |
| Staiano, A | 1 |
| Izzo, P | 1 |
| De Rosa, M | 1 |
| Hamzaoui, L | 1 |
| Kilani, H | 1 |
| Bouassida, M | 1 |
| Mahmoudi, M | 1 |
| Chalbi, E | 1 |
| Siai, K | 1 |
| Ezzine, H | 1 |
| Touinsi, H | 1 |
| Azzouz, MM | 1 |
| Sassi, S | 1 |
| Indriolo, A | 1 |
| Ravelli, P | 1 |
| Chapman, CG | 1 |
| Rubin, DT | 1 |
| Svrcek, M | 1 |
| Beaugerie, L | 1 |
| Kirchgesner, J | 1 |
| Dumont, S | 1 |
| Muleris, M | 1 |
| Bodo, S | 1 |
| Dartigues, P | 1 |
| Lascols, O | 1 |
| Seksik, P | 1 |
| Cosnes, J | 1 |
| Fléjou, JF | 1 |
| Duval, A | 1 |
| Cheddani, H | 1 |
| Dauchet, L | 1 |
| Fumery, M | 1 |
| Charpentier, C | 1 |
| Marie Bouvier, A | 1 |
| Dupas, JL | 1 |
| Pariente, B | 1 |
| Peyrin-Biroulet, L | 1 |
| Savoye, G | 1 |
| Gower-Rousseau, C | 1 |
| Ray, G | 1 |
| van Schaik, FD | 1 |
| van Oijen, MG | 1 |
| Smeets, HM | 1 |
| van der Heijden, GJ | 1 |
| Siersema, PD | 1 |
| Oldenburg, B | 1 |
| Chaparro, M | 1 |
| Trapero-Marugán, M | 1 |
| Guijarro, M | 1 |
| López, C | 1 |
| Moreno-Otero, R | 1 |
| Gisbert, JP | 1 |
| Yajima, T | 1 |
| Hibi, T | 1 |
| Fraser, AG | 1 |
| Orchard, TR | 1 |
| Robinson, EM | 1 |
| Jewell, DP | 1 |
| Rammert, Ch | 1 |
| Kullak-Ublick, GA | 1 |
| Jess, T | 1 |
| Winther, KV | 1 |
| Munkholm, P | 1 |
| Langholz, E | 1 |
| Binder, V | 1 |
| Kruis, W | 2 |
| Schreiber, S | 1 |
| Vetter, C | 1 |
| Matula, S | 1 |
| Croog, V | 1 |
| Itzkowitz, S | 1 |
| Harpaz, N | 1 |
| Bodian, C | 1 |
| Hossain, S | 1 |
| Ullman, T | 1 |
| Dixon, A | 1 |
| Wurm, P | 1 |
| Hart, A | 1 |
| Robinson, R | 1 |
| Allgayer, H | 1 |
| Levine, JS | 1 |
| Burakoff, R | 1 |
| Lakatos, L | 1 |
| Lakatos, PL | 1 |
| Rodríguez-Moranta, F | 1 |
| Soriano-Izquierdo, A | 1 |
| Guardiola, J | 1 |
| Camilleri, M | 1 |
| Saito, YA | 1 |
| Marion, JF | 1 |
| Zhu, Z | 1 |
| Mei, Z | 1 |
| Guo, Y | 1 |
| Wang, G | 1 |
| Wu, T | 1 |
| Cui, X | 1 |
| Huang, Z | 1 |
| Zhu, Y | 1 |
| Wen, D | 1 |
| Song, J | 1 |
| He, H | 1 |
| Xu, W | 1 |
| Cui, L | 1 |
| Liu, C | 1 |
12 reviews available for azathioprine and Colorectal Neoplasms
| Article | Year |
|---|---|
Use of thiopurines and risk of colorectal neoplasia in patients with inflammatory bowel diseases: a meta-analysis.
Topics: Azathioprine; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Risk | 2013 |
Clinical management of inflammatory bowel disease in the organ recipient.
Topics: Azathioprine; Cholangitis, Sclerosing; Colectomy; Colorectal Neoplasms; End Stage Liver Disease; Gra | 2014 |
The potential for medical therapy to reduce the risk of colorectal cancer and optimize surveillance in inflammatory bowel disease.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; | 2014 |
Inflammatory bowel disease in India - Past, present and future.
Topics: Aminosalicylic Acid; Antitubercular Agents; Asia, Southeastern; Azathioprine; Biological Products; B | 2016 |
[For treatment decision the age to be taken into account. In Crohn's disease and ulcerative colitis attention to be paid to the age at manifestation].
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi | 2009 |
Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Cholangitis, S | 2013 |
[Management of ulcerative colitis].
Topics: Administration, Oral; Adrenal Cortex Hormones; Aminosalicylic Acids; Anemia; Anti-Inflammatory Agent | 2003 |
Chemoprophylaxis of colorectal cancer in inflammatory bowel disease: current concepts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; Colorectal Neopl | 2007 |
[Medical therapy of inflammatory bowel diseases: ulcerative colitis].
Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2007 |
[Current status of treatment of inflammatory bowel disease].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, H | 2007 |
Pharmacogenomics in gastrointestinal disorders.
Topics: Antineoplastic Agents; Azathioprine; Biotransformation; Colorectal Neoplasms; Gastrointestinal Agent | 2008 |
Reduced Risk of Inflammatory Bowel Disease-associated Colorectal Neoplasia with Use of Thiopurines: a Systematic Review and Meta-analysis.
Topics: Colorectal Neoplasms; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Merc | 2018 |
20 other studies available for azathioprine and Colorectal Neoplasms
| Article | Year |
|---|---|
A case of iatrogenic immunodeficiency-associated colonic lymphoma complicating ulcerative colitis.
Topics: Aged; Azathioprine; Colitis, Ulcerative; Colorectal Neoplasms; Humans; Iatrogenic Disease; Immunocom | 2020 |
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Multifocal colorectal non-Hodgkin's lymphoma in a patient with ulcerative colitis: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biopsy; Colitis, Ulcerative; Col | 2021 |
Editorial: weighing the global risk of cancer with thiopurines in inflammatory bowel disease.
Topics: Azathioprine; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases | 2018 |
Iatrogenic colorectal Kaposi's sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient.
Topics: Adrenal Cortex Hormones; Azathioprine; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Herpesv | 2017 |
Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Azathioprine; Colorectal Neopl | 2020 |
Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.
Topics: Adenomatous Polyposis Coli; Age of Onset; Anti-Infective Agents; Azathioprine; beta Catenin; Biomark | 2013 |
Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient.
Topics: Adult; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Colorectal Neoplasms; HIV Seronega | 2013 |
Azathioprine May Not be Associated With Development of Colorectal Tumors With Microsatellite Instability in Patients With Inflammatory Bowel Disease.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Colorectal Neoplasms; Female; Humans; Inflammatory Bow | 2016 |
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi | 2016 |
Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cohort Studies; Colorectal Neoplasms; | 2012 |
[Chemoprevention of colorectal cancer associated with IBD].
Topics: Azathioprine; Colorectal Neoplasms; Crohn Disease; Folic Acid; Humans; Inflammatory Bowel Diseases; | 2012 |
Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine.
Topics: Adolescent; Adult; Age Distribution; Aged; Azathioprine; Colorectal Neoplasms; Drug Administration S | 2002 |
Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hor | 2004 |
[Ulcerative colitis. Maintenance therapy].
Topics: Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-St | 2004 |
[Chronic inflammatory bowel diseases. Recurrence prevention = carcinoma prevention?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholangitis, Sclerosing; Colitis, Ulcerative; | 2005 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine.
Topics: Adult; Azathioprine; Cell Transformation, Neoplastic; Colitis, Ulcerative; Colorectal Neoplasms; Dis | 2005 |
Distal adenomatous polyps are rare in patients with inflammatory bowel disease.
Topics: Adenomatous Polyps; Antimetabolites, Antineoplastic; Azathioprine; Case-Control Studies; Colorectal | 2006 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Azathioprine; Colitis, Ulc | 2006 |
Toxicity of 6-mercaptopurine/azathioprine in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Child; Colorectal Neoplasms; Drug Hypersensitivity; Fe | 1998 |