azathioprine has been researched along with Colorectal Cancer in 32 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year-old woman was treated for colorectal diffuse large B-cell lymphoma (DLBCL) after a prolonged treatment period of azathioprine (AZA) and infliximab (IFX) for Crohn's disease (CD)." | 7.96 | Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine. ( Daikuhara, S; Hirayama, A; Sato, K; Suga, T; Tanaka, E; Uehara, T, 2020) |
| "A 52-year-old woman was treated for colorectal diffuse large B-cell lymphoma (DLBCL) after a prolonged treatment period of azathioprine (AZA) and infliximab (IFX) for Crohn's disease (CD)." | 3.96 | Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine. ( Daikuhara, S; Hirayama, A; Sato, K; Suga, T; Tanaka, E; Uehara, T, 2020) |
| "UC related colorectal cancer develop in an unpredictable manner with respect to disease duration and site questioning the validity of strict screening protocol." | 2.53 | Inflammatory bowel disease in India - Past, present and future. ( Ray, G, 2016) |
| "An increased risk of colorectal cancer (CRC) is present also after LT in IBD patients with primary sclerosing cholangitis (PSC)." | 2.50 | Clinical management of inflammatory bowel disease in the organ recipient. ( Indriolo, A; Ravelli, P, 2014) |
| "Primary sclerosing cholangitis is a chronic progressive disorder which involves the medium size and large ducts in the intrahepatic and extrahepatic biliary tree." | 2.49 | Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature. ( Chaparro, M; Gisbert, JP; Guijarro, M; López, C; Moreno-Otero, R; Trapero-Marugán, M, 2013) |
| "Ulcerative colitis is a chronic inflammatory bowel disease." | 2.42 | [Management of ulcerative colitis]. ( Kullak-Ublick, GA; Rammert, Ch, 2003) |
| "Kaposi sarcoma is an unusual tumor associated to a human herpes virus-8 infection involving the skin or internal organs." | 1.46 | Iatrogenic colorectal Kaposi's sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient. ( Amouri, A; Ayedi, L; Boudabous, M; Boudaouara, T; Chtourou, L; Grati, A; Mnif, L; Mzali, R; Rejab, H; Tahri, N, 2017) |
| "No significant risk for other intestinal cancers was found, especially for small bowel carcinoma." | 1.43 | Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016) |
| "Kaposi sarcoma is a mesenchymal tumor associated to a human herpes virus-8." | 1.39 | Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient. ( Azzouz, MM; Bouassida, M; Chalbi, E; Ezzine, H; Hamzaoui, L; Kilani, H; Mahmoudi, M; Sassi, S; Siai, K; Touinsi, H, 2013) |
| "There is an increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD)." | 1.33 | Distal adenomatous polyps are rare in patients with inflammatory bowel disease. ( Dixon, A; Hart, A; Robinson, R; Wurm, P, 2006) |
| "The risk of colorectal cancer was not increased, either in the total group of patients or in patients with colonic Crohn's disease exclusively (standardized morbidity ratio, 1." | 1.32 | Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark. ( Binder, V; Jess, T; Langholz, E; Munkholm, P; Winther, KV, 2004) |
| "Azathioprine was given to 626 of 2204 patients (855 with Crohn's disease and 1349 with ulcerative colitis)." | 1.31 | Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine. ( Fraser, AG; Jewell, DP; Orchard, TR; Robinson, EM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, K | 1 |
| Ohe, R | 1 |
| Kabasawa, T | 1 |
| Aung, NY | 1 |
| Yano, M | 1 |
| Katsumi, S | 1 |
| Yanagiya, R | 1 |
| Yamamoto, M | 1 |
| Toubai, T | 1 |
| Ishizawa, K | 1 |
| Yamakawa, M | 1 |
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Walinjkar, S | 1 |
| Kumar, A | 1 |
| Sharma, P | 1 |
| Gupta, P | 1 |
| Bansal, N | 1 |
| Singla, V | 1 |
| Anikhindi, SA | 1 |
| Arora, A | 1 |
| Laharie, D | 1 |
| Riviere, P | 1 |
| Chtourou, L | 1 |
| Ayedi, L | 1 |
| Rejab, H | 1 |
| Boudabous, M | 1 |
| Mnif, L | 1 |
| Grati, A | 1 |
| Boudaouara, T | 1 |
| Mzali, R | 1 |
| Amouri, A | 1 |
| Tahri, N | 1 |
| Sato, K | 1 |
| Suga, T | 1 |
| Hirayama, A | 1 |
| Daikuhara, S | 1 |
| Uehara, T | 1 |
| Tanaka, E | 1 |
| Gong, J | 1 |
| Zhu, L | 1 |
| Guo, Z | 1 |
| Li, Y | 1 |
| Zhu, W | 1 |
| Li, N | 1 |
| Li, J | 1 |
| Galatola, M | 1 |
| Miele, E | 1 |
| Strisciuglio, C | 1 |
| Paparo, L | 1 |
| Rega, D | 1 |
| Delrio, P | 1 |
| Duraturo, F | 1 |
| Martinelli, M | 1 |
| Rossi, GB | 1 |
| Staiano, A | 1 |
| Izzo, P | 1 |
| De Rosa, M | 1 |
| Hamzaoui, L | 1 |
| Kilani, H | 1 |
| Bouassida, M | 1 |
| Mahmoudi, M | 1 |
| Chalbi, E | 1 |
| Siai, K | 1 |
| Ezzine, H | 1 |
| Touinsi, H | 1 |
| Azzouz, MM | 1 |
| Sassi, S | 1 |
| Indriolo, A | 1 |
| Ravelli, P | 1 |
| Chapman, CG | 1 |
| Rubin, DT | 1 |
| Svrcek, M | 1 |
| Beaugerie, L | 1 |
| Kirchgesner, J | 1 |
| Dumont, S | 1 |
| Muleris, M | 1 |
| Bodo, S | 1 |
| Dartigues, P | 1 |
| Lascols, O | 1 |
| Seksik, P | 1 |
| Cosnes, J | 1 |
| Fléjou, JF | 1 |
| Duval, A | 1 |
| Cheddani, H | 1 |
| Dauchet, L | 1 |
| Fumery, M | 1 |
| Charpentier, C | 1 |
| Marie Bouvier, A | 1 |
| Dupas, JL | 1 |
| Pariente, B | 1 |
| Peyrin-Biroulet, L | 1 |
| Savoye, G | 1 |
| Gower-Rousseau, C | 1 |
| Ray, G | 1 |
| van Schaik, FD | 1 |
| van Oijen, MG | 1 |
| Smeets, HM | 1 |
| van der Heijden, GJ | 1 |
| Siersema, PD | 1 |
| Oldenburg, B | 1 |
| Chaparro, M | 1 |
| Trapero-Marugán, M | 1 |
| Guijarro, M | 1 |
| López, C | 1 |
| Moreno-Otero, R | 1 |
| Gisbert, JP | 1 |
| Yajima, T | 1 |
| Hibi, T | 1 |
| Fraser, AG | 1 |
| Orchard, TR | 1 |
| Robinson, EM | 1 |
| Jewell, DP | 1 |
| Rammert, Ch | 1 |
| Kullak-Ublick, GA | 1 |
| Jess, T | 1 |
| Winther, KV | 1 |
| Munkholm, P | 1 |
| Langholz, E | 1 |
| Binder, V | 1 |
| Kruis, W | 2 |
| Schreiber, S | 1 |
| Vetter, C | 1 |
| Matula, S | 1 |
| Croog, V | 1 |
| Itzkowitz, S | 1 |
| Harpaz, N | 1 |
| Bodian, C | 1 |
| Hossain, S | 1 |
| Ullman, T | 1 |
| Dixon, A | 1 |
| Wurm, P | 1 |
| Hart, A | 1 |
| Robinson, R | 1 |
| Allgayer, H | 1 |
| Levine, JS | 1 |
| Burakoff, R | 1 |
| Lakatos, L | 1 |
| Lakatos, PL | 1 |
| Rodríguez-Moranta, F | 1 |
| Soriano-Izquierdo, A | 1 |
| Guardiola, J | 1 |
| Camilleri, M | 1 |
| Saito, YA | 1 |
| Marion, JF | 1 |
| Zhu, Z | 1 |
| Mei, Z | 1 |
| Guo, Y | 1 |
| Wang, G | 1 |
| Wu, T | 1 |
| Cui, X | 1 |
| Huang, Z | 1 |
| Zhu, Y | 1 |
| Wen, D | 1 |
| Song, J | 1 |
| He, H | 1 |
| Xu, W | 1 |
| Cui, L | 1 |
| Liu, C | 1 |
12 reviews available for azathioprine and Colorectal Cancer
| Article | Year |
|---|---|
Use of thiopurines and risk of colorectal neoplasia in patients with inflammatory bowel diseases: a meta-analysis.
Topics: Azathioprine; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Risk | 2013 |
Clinical management of inflammatory bowel disease in the organ recipient.
Topics: Azathioprine; Cholangitis, Sclerosing; Colectomy; Colorectal Neoplasms; End Stage Liver Disease; Gra | 2014 |
The potential for medical therapy to reduce the risk of colorectal cancer and optimize surveillance in inflammatory bowel disease.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; | 2014 |
Inflammatory bowel disease in India - Past, present and future.
Topics: Aminosalicylic Acid; Antitubercular Agents; Asia, Southeastern; Azathioprine; Biological Products; B | 2016 |
[For treatment decision the age to be taken into account. In Crohn's disease and ulcerative colitis attention to be paid to the age at manifestation].
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi | 2009 |
Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Cholangitis, S | 2013 |
[Management of ulcerative colitis].
Topics: Administration, Oral; Adrenal Cortex Hormones; Aminosalicylic Acids; Anemia; Anti-Inflammatory Agent | 2003 |
Chemoprophylaxis of colorectal cancer in inflammatory bowel disease: current concepts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; Colorectal Neopl | 2007 |
[Medical therapy of inflammatory bowel diseases: ulcerative colitis].
Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2007 |
[Current status of treatment of inflammatory bowel disease].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, H | 2007 |
Pharmacogenomics in gastrointestinal disorders.
Topics: Antineoplastic Agents; Azathioprine; Biotransformation; Colorectal Neoplasms; Gastrointestinal Agent | 2008 |
Reduced Risk of Inflammatory Bowel Disease-associated Colorectal Neoplasia with Use of Thiopurines: a Systematic Review and Meta-analysis.
Topics: Colorectal Neoplasms; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Merc | 2018 |
20 other studies available for azathioprine and Colorectal Cancer
| Article | Year |
|---|---|
A case of iatrogenic immunodeficiency-associated colonic lymphoma complicating ulcerative colitis.
Topics: Aged; Azathioprine; Colitis, Ulcerative; Colorectal Neoplasms; Humans; Iatrogenic Disease; Immunocom | 2020 |
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Multifocal colorectal non-Hodgkin's lymphoma in a patient with ulcerative colitis: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biopsy; Colitis, Ulcerative; Col | 2021 |
Editorial: weighing the global risk of cancer with thiopurines in inflammatory bowel disease.
Topics: Azathioprine; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases | 2018 |
Iatrogenic colorectal Kaposi's sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient.
Topics: Adrenal Cortex Hormones; Azathioprine; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Herpesv | 2017 |
Diffuse large B-cell lymphoma of the colon and rectum in a patient with colonic Crohn's disease treated with infliximab and azathioprine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Azathioprine; Colorectal Neopl | 2020 |
Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.
Topics: Adenomatous Polyposis Coli; Age of Onset; Anti-Infective Agents; Azathioprine; beta Catenin; Biomark | 2013 |
Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient.
Topics: Adult; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Colorectal Neoplasms; HIV Seronega | 2013 |
Azathioprine May Not be Associated With Development of Colorectal Tumors With Microsatellite Instability in Patients With Inflammatory Bowel Disease.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Colorectal Neoplasms; Female; Humans; Inflammatory Bow | 2016 |
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi | 2016 |
Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cohort Studies; Colorectal Neoplasms; | 2012 |
[Chemoprevention of colorectal cancer associated with IBD].
Topics: Azathioprine; Colorectal Neoplasms; Crohn Disease; Folic Acid; Humans; Inflammatory Bowel Diseases; | 2012 |
Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine.
Topics: Adolescent; Adult; Age Distribution; Aged; Azathioprine; Colorectal Neoplasms; Drug Administration S | 2002 |
Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hor | 2004 |
[Ulcerative colitis. Maintenance therapy].
Topics: Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-St | 2004 |
[Chronic inflammatory bowel diseases. Recurrence prevention = carcinoma prevention?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholangitis, Sclerosing; Colitis, Ulcerative; | 2005 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine.
Topics: Adult; Azathioprine; Cell Transformation, Neoplastic; Colitis, Ulcerative; Colorectal Neoplasms; Dis | 2005 |
Distal adenomatous polyps are rare in patients with inflammatory bowel disease.
Topics: Adenomatous Polyps; Antimetabolites, Antineoplastic; Azathioprine; Case-Control Studies; Colorectal | 2006 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Azathioprine; Colitis, Ulc | 2006 |
Toxicity of 6-mercaptopurine/azathioprine in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Child; Colorectal Neoplasms; Drug Hypersensitivity; Fe | 1998 |