Page last updated: 2024-10-23

azathioprine and Colonic Diseases

azathioprine has been researched along with Colonic Diseases in 18 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).

Research Excerpts

ExcerptRelevanceReference
"A 16-year-old woman with MG developed hair loss, pancytopenia, bloody diarrhea, and fever shortly after azathioprine treatment."8.12Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report. ( Hsu, WY; Lin, LC; Lin, PC; Liu, YC, 2022)
"Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease."5.31A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline. ( Kasahara, E; Tanaka, M; Yamagishi, N; Yashiro, K, 2002)
"A 16-year-old woman with MG developed hair loss, pancytopenia, bloody diarrhea, and fever shortly after azathioprine treatment."4.12Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report. ( Hsu, WY; Lin, LC; Lin, PC; Liu, YC, 2022)
" The patients who achieved a complete remission with medical treatment, who had no history of intestinal perforation, and who received azathioprine after operation showed better clinical courses."3.70Long-term clinical course and prognostic factors in intestinal Behçet's disease. ( Cha, SD; Choi, IJ; Jung, HC; Kim, CY; Kim, JS; Park, JG; Song, IS, 2000)
"Fistulas are common in patients with Crohn's disease and, when associated with inflammatory disease and established for several weeks, tend to be chronic."2.41Management of fistulas in patients with Crohn's disease: antibiotic to antibody. ( Paré, P, 2001)
"Of a total 44 patients with Crohn's disease, 10 patients with 9 internal and 15 external fistulae, some of which were recurrent, were analyzed at the Department of Surgery, Yokohama City University between 1973 and 1988."2.38The medical, nutritional and surgical treatment of fistulae in Crohn's disease. ( Fukushima, T; Sugita, A; Takemura, H; Tsuchiya, S; Yamazaki, Y, 1990)
"Early sepsis was seen in 58 patients (17."1.34The impact of preoperative immunomodulation on pouch-related septic complications after ileal pouch-anal anastomosis. ( Abdulgader, A; Burke, D; Lim, M; Sagar, P; Thekkinkattil, D, 2007)
"Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease."1.31A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline. ( Kasahara, E; Tanaka, M; Yamagishi, N; Yashiro, K, 2002)
"Sulfasalazine alone was used in 24 patients, steroids alone were used in four patients, both drugs were used together in 29 patients and azathioprine was added to the drug regimen of five patients."1.26Anti-inflammatory drug treatment in Crohn's disease. ( Abramson, J; Goldstein, F; Thornton, JJ, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's2 (11.11)18.2507
2000's4 (22.22)29.6817
2010's2 (11.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Hsu, WY1
Lin, PC1
Liu, YC1
Lin, LC1
Cappello, M1
Bravatà, I1
Cocorullo, G1
Cacciatore, M1
Florena, AM1
Kim, KJ1
Han, BJ1
Yang, SK1
Na, SY1
Park, SK1
Boo, SJ1
Park, SH1
Yang, DH1
Park, JH1
Jeong, KW1
Ye, BD1
Byeon, JS1
Myung, SJ1
Kim, JH1
Kasahara, E1
Yamagishi, N1
Tanaka, M1
Yashiro, K1
Lim, M1
Sagar, P1
Abdulgader, A1
Thekkinkattil, D1
Burke, D1
Glasbrenner, B1
Güthner, C1
Röcken, C1
Mattfeld, T1
Hetzel, W1
Adler, G1
Choi, IJ1
Kim, JS1
Cha, SD1
Jung, HC1
Park, JG1
Song, IS1
Kim, CY1
Paré, P1
Goldstein, F1
Thornton, JJ1
Abramson, J1
Allan, R1
Steinberg, DM1
Williams, JA2
Cooke, WT1
Zanghì, M1
Yamazaki, Y1
Fukushima, T1
Sugita, A1
Takemura, H1
Tsuchiya, S1
Miller, B1
Martini, GA1
Mallinson, CN1
Candy, JC1
Cowan, R1
Prior, A1
Cassano, C1
Torsoli, A1
Perlmann, P1
Javett, SL1
Kavin, H1
Bremner, CG1
Schneider, J1
Levine, E1
Hinder, RA1
Chantar Barrios, C1

Reviews

5 reviews available for azathioprine and Colonic Diseases

ArticleYear
Management of fistulas in patients with Crohn's disease: antibiotic to antibody.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2001, Volume: 15, Issue:11

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Azathioprine; Colonic Diseases; Crohn Disease; Cyclos

2001
The medical, nutritional and surgical treatment of fistulae in Crohn's disease.
    The Japanese journal of surgery, 1990, Volume: 20, Issue:4

    Topics: Adult; Azathioprine; Colonic Diseases; Combined Modality Therapy; Crohn Disease; Enteral Nutrition;

1990
[What is secured in the therapy of chronic inflammatory colonic diseases?].
    Der Internist, 1974, Volume: 15, Issue:12

    Topics: Administration, Topical; Amebiasis; Azathioprine; Chronic Disease; Colitis; Colitis, Ulcerative; Col

1974
[Treatment of granulomatous colitis. Crohn's disease of the colon].
    Revista clinica espanola, 1970, Dec-15, Volume: 119, Issue:5

    Topics: Anti-Bacterial Agents; Azathioprine; Colonic Diseases; Crohn Disease; Diet Therapy; Gastrointestinal

1970
The place of surgery in Crohn's disease.
    Gut, 1971, Volume: 12, Issue:9

    Topics: Abscess; Acute Disease; Anemia; Appendectomy; Azathioprine; Colectomy; Colonic Diseases; Crohn Disea

1971

Other Studies

13 other studies available for azathioprine and Colonic Diseases

ArticleYear
Alopecia and colon ulcers following azathioprine use in a patient with myasthenia gravis: A case report.
    Medicine, 2022, Aug-19, Volume: 101, Issue:33

    Topics: Adolescent; Alopecia; Azathioprine; Colonic Diseases; Diarrhea; Female; Humans; Myasthenia Gravis; P

2022
Splenic littoral cell hemangioendothelioma in a patient with Crohn's disease previously treated with immunomodulators and anti-TNF agents: a rare tumor linked to deep immunosuppression.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:10

    Topics: Azathioprine; Colonic Diseases; Crohn Disease; Gastrointestinal Agents; Hemangioendothelioma; Hemang

2011
Risk factors and outcome of acute severe lower gastrointestinal bleeding in Crohn's disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:9

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-

2012
A child with simple ulcer of the colon effectively treated with the combination of prednisolone, azathioprine, and pentoxifylline.
    Journal of gastroenterology, 2002, Volume: 37, Issue:9

    Topics: Anti-Inflammatory Agents; Azathioprine; Child; Colonic Diseases; Drug Therapy, Combination; Enzyme I

2002
The impact of preoperative immunomodulation on pouch-related septic complications after ileal pouch-anal anastomosis.
    Diseases of the colon and rectum, 2007, Volume: 50, Issue:7

    Topics: Adult; Anal Canal; Anastomosis, Surgical; Azathioprine; Colonic Diseases; Colonic Pouches; Cyclospor

2007
[56-year-old patient with segmental florid colitis and colonic amyloidosis].
    Der Internist, 1999, Volume: 40, Issue:6

    Topics: Amyloidosis; Azathioprine; Colitis; Colonic Diseases; Colonoscopy; Crohn Disease; Diagnosis, Differe

1999
Long-term clinical course and prognostic factors in intestinal Behçet's disease.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Behcet Syndrome; Colectomy; Colonic Diseases; Colonoscopy; Combined

2000
Anti-inflammatory drug treatment in Crohn's disease.
    The American journal of gastroenterology, 1976, Volume: 66, Issue:3

    Topics: Anti-Inflammatory Agents; Azathioprine; Colonic Diseases; Crohn Disease; Female; Humans; Intestinal

1976
Crohn's disease involving the colon: an audit of clinical management.
    Gastroenterology, 1977, Volume: 73, Issue:4 Pt 1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Child;

1977
[Diagnosis and therapy of Crohn's disease of the colon].
    Minerva chirurgica, 1977, Jun-30, Volume: 32, Issue:12

    Topics: Azathioprine; Colonic Diseases; Cortisone; Crohn Disease; Humans

1977
Two first degree relatives with dilatation of the colon due to Crohn's disease.
    Guy's Hospital reports, 1973, Volume: 122, Issue:3-4

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Azathioprine; Body Weight; Colectomy; Colitis, Ulcer

1973
[Ulcerative colitis and Crohn's disease of the colon. Problems of diagnosis and therapy. Immunological aspects].
    Minerva medica, 1972, Dec-08, Volume: 63, Issue:88

    Topics: Antigens, Heterophile; Autoantibodies; Azathioprine; Colitis, Ulcerative; Colonic Diseases; Cortison

1972
Some aspects of Crohn's disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-11, Volume: 47, Issue:31

    Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise

1973