azathioprine has been researched along with Colitis in 56 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Excerpt | Relevance | Reference |
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"To investigate the efficacy of azathioprine as maintenance therapy in acute severe colitis of Crohn's disease or ulcerative colitis after successful treatment by intravenous corticosteroids." | 9.13 | [Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study]. ( Belkhodja, A; Boubaker, J; Djebbi, S; Filali, A; Karoui, S, 2008) |
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine." | 9.09 | Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999) |
"A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 9.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
"We prospectively investigated colonoscopic biopsies from five groups of 20 subjects each: patients with ulcerative or indeterminate colitis treated with azathioprine (group 1), azathioprine and 5-ASA (group 2), 5-ASA (group 3), untreated IBD (group 4), and healthy controls." | 7.74 | Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis. ( Bengmark, S; Dörffel, Y; Lochs, H; Loening-Baucke, V; Swidsinski, A, 2007) |
"To investigate the efficacy of azathioprine as maintenance therapy in acute severe colitis of Crohn's disease or ulcerative colitis after successful treatment by intravenous corticosteroids." | 5.13 | [Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study]. ( Belkhodja, A; Boubaker, J; Djebbi, S; Filali, A; Karoui, S, 2008) |
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine." | 5.09 | Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999) |
"A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period." | 5.04 | Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975) |
" We report the case of a 50-year-old patient with indeterminate colitis, presenting with a febrile diffuse papulopustular and necrotizing skin eruption that healed with significant scarring and appeared 14 days after onset of treatment with azathioprine." | 4.91 | Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature. ( Contassot, E; Frei, P; French, LE; Imhof, L; Kamarachev, J; Kolios, A; Meier, B; Navarini, AA; Rogler, G, 2015) |
"IBD patients who previously failed azathioprine or mercaptopurine and initiated thioguanine were prospectively followed for 12 months starting when corticosteroid-free clinical remission was achieved (Harvey-Bradshaw Index [HBI] ≤ 4 or Simple Clinical Colitis Activity Index [SCCAI] ≤ 2)." | 4.31 | Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study. ( Boekema, P; de Boer, N; de Leest, M; Dijkstra, G; Fidder, H; Gisbertz, I; Hoentjen, F; Jharap, B; Kaplan, S; Kubben, F; Meijssen, M; Mulder, CJJ; Petrak, A; Russel, M; Schepers, F; Simsek, M; van Asseldonk, D; van Bodegraven, AA; van Boeckel, P; van de Poel, E, 2023) |
"We report a case of severe colitis that led to the diagnosis of HPS, which was responsive to azathioprine and infliximab." | 3.91 | Crohn's-like acute severe colitis associated with Hermansky-Pudlak syndrome: A case report. ( Bourreille, A; De Maissin, A; Freyssinet, M; Girot, P; Le Berre, C; Trang-Poisson, C, 2019) |
"We prospectively investigated colonoscopic biopsies from five groups of 20 subjects each: patients with ulcerative or indeterminate colitis treated with azathioprine (group 1), azathioprine and 5-ASA (group 2), 5-ASA (group 3), untreated IBD (group 4), and healthy controls." | 3.74 | Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis. ( Bengmark, S; Dörffel, Y; Lochs, H; Loening-Baucke, V; Swidsinski, A, 2007) |
" However, the dosing and the duration of immunosuppressive therapy have not been systematically studied in the setting of treating ipilimumab-induced irAEs." | 2.52 | Ipilimumab-induced toxicities and the gastroenterologist. ( Bye, W; Cheng, R; Cooper, A; Kench, J; McNeil, C; Shackel, N; Watson, G, 2015) |
"Whereas the incidence of ulcerative colitis has remained stable at around 8-9/10(5), the incidence of Crohn's disease has increased from below 1 to more than 5/10(5) per year during the last three decades." | 2.41 | [Therapeutic principles for chronic inflammatory bowel disease]. ( Binder, V; Munkholm, P, 2001) |
" wexlerae colonization reduced 6-mercaptopurine (6-MP) bioavailability by enhancing selenium-dependent xanthine dehydrogenase (sd-XDH) activity." | 1.91 | Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability. ( Chen, H; Cui, Z; Fang, JY; Gao, Z; Hong, J; Hu, M; Huang, X; Ma, Y; Ning, L; Tong, T; Wang, Z; Xuan, B; Yan, Y; Zhao, Y; Zhou, YL, 2023) |
"Microscopic colitis is characterized by chronic or intermittent watery diarrhoea." | 1.39 | [Microscopic colitis]. ( Lukáš, K; Mandys, V, 2013) |
"Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events." | 1.37 | Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis. ( de Boer, NK; Jharap, B; Klimesova, K; Kverka, M; Lukas, M; Mulder, CJ; Rossmann, P; Tlaskalova-Hogenova, H; van Bodegraven, AA; Vos, RM, 2011) |
"Diagnostic criteria for CD, ulcerative colitis (UC), and indeterminate colitis (IC) were defined." | 1.33 | Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease. ( Bonova, O; Dedek, P; Frühauf, P; Havlickova, A; Janatova, T; Jimramovsky, F; Klimova, L; Klusacek, D; Kocourkova, D; Kolek, A; Kotalova, R; Maly, J; Marx, D; Nevoral, J; Petro, R; Petru, O; Plasilova, I; Pozler, O; Schreierova, I; Seidl, Z; Sekyrova, I; Semendak, N; Stanek, J; Sulakova, A; Sykora, J; Toukalkova, L; Travnickova, R; Volf, V; Zahradnicek, L; Zenisková, I, 2006) |
"6-mercaptopurine/azathioprine was used by 24% of patients with Crohn's disease and 12% of patients with ulcerative colitis (95% CI for the difference: 8." | 1.32 | A national survey on the patterns of treatment of inflammatory bowel disease in Canada. ( Best, A; Hilsden, RJ; Pocobelli, G; Verhoef, MJ, 2003) |
"Collagenous colitis is one of the microscopic colitides, which are thought to be on the same spectrum of disease as Crohn's disease and ulcerative colitis." | 1.32 | Pyoderma gangrenosum in a patient with collagenous colitis. ( Batra, AK; Levey, JM; Patwardhan, R; Trister, J, 2003) |
"An exacerbation of the myelitis, retinitis, encephalitis and colitis was observed and a cytomegalovirus infection diagnosed." | 1.31 | CMV complications in common variable immunodeficiency. ( Schmidt, RE; Werwitzke, S; Witte, T, 2000) |
"To ascertain whether patients with Crohn's disease treated with azathioprine maintained bone mineral mass better than patients treated with steroids alone." | 1.30 | Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine. ( Ahrén, B; Bartosik, J; Bengtsson, M; Florén, CH; Obrant, K, 1998) |
"Eighty-one percent had Crohn's disease, 8% ulcerative colitis, and 11% indeterminant colitis." | 1.29 | Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum. ( Daum, F; Grancher, K; Mandel, F; Markowitz, J, 1993) |
"Azathioprine (AZ) has been used in the treatment of refractory inflammatory bowel disease." | 1.28 | Azathioprine reduces extravasation and neutrophil trafficking in immune complex-mediated inflammation in the rat colon. ( Anania, T; Clearfield, HR; Murthy, SN, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (19.64) | 18.7374 |
1990's | 8 (14.29) | 18.2507 |
2000's | 14 (25.00) | 29.6817 |
2010's | 16 (28.57) | 24.3611 |
2020's | 7 (12.50) | 2.80 |
Authors | Studies |
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Simsek, M | 1 |
Schepers, F | 1 |
Kaplan, S | 1 |
van Asseldonk, D | 1 |
van Boeckel, P | 1 |
Boekema, P | 1 |
Dijkstra, G | 1 |
Fidder, H | 1 |
Gisbertz, I | 1 |
Hoentjen, F | 1 |
Jharap, B | 2 |
Kubben, F | 1 |
de Leest, M | 1 |
Meijssen, M | 1 |
Petrak, A | 1 |
van de Poel, E | 1 |
Russel, M | 1 |
van Bodegraven, AA | 2 |
Mulder, CJJ | 1 |
de Boer, N | 1 |
Yan, Y | 1 |
Wang, Z | 1 |
Zhou, YL | 1 |
Gao, Z | 1 |
Ning, L | 1 |
Zhao, Y | 1 |
Xuan, B | 1 |
Ma, Y | 1 |
Tong, T | 1 |
Huang, X | 1 |
Hu, M | 1 |
Fang, JY | 1 |
Cui, Z | 1 |
Chen, H | 1 |
Hong, J | 1 |
Booth, AT | 1 |
Forster, E | 1 |
Curran, T | 1 |
George, V | 1 |
Zhang, Y | 1 |
Li, D | 1 |
Guo, H | 1 |
Wang, W | 1 |
Li, X | 1 |
Shen, S | 1 |
Fraser, AG | 1 |
Vasudevan, A | 1 |
Con, D | 1 |
Nicolaides, S | 1 |
van Langenberg, DR | 1 |
Imperatore, N | 1 |
Foggia, M | 1 |
Patturelli, M | 1 |
Rispo, A | 1 |
Calabrese, G | 1 |
Testa, A | 1 |
Pellegrini, L | 1 |
Tosone, G | 1 |
Di Luna, I | 1 |
Nardone, OM | 1 |
Ricciolino, S | 1 |
Castiglione, F | 1 |
Lin, G | 1 |
Li, M | 1 |
Xu, N | 1 |
Wu, X | 1 |
Liu, J | 1 |
Wu, Y | 1 |
Zhang, Q | 1 |
Cai, J | 1 |
Gao, C | 1 |
Su, Z | 1 |
Ameneiros-Lago, E | 1 |
Pérez-Valcarcel, J | 1 |
Fernández-Fernández, FJ | 1 |
Caínzos-Romero, T | 1 |
Weder, B | 1 |
Mozaffari, M | 1 |
Biedermann, L | 1 |
Mamie, C | 1 |
Moncsek, A | 1 |
Wang, L | 1 |
Clarke, SH | 1 |
Rogler, G | 2 |
McRae, BL | 1 |
Graff, CL | 1 |
Ruiz, PA | 1 |
Hausmann, M | 1 |
Khare, V | 1 |
Krnjic, A | 1 |
Frick, A | 1 |
Gmainer, C | 1 |
Asboth, M | 1 |
Jimenez, K | 1 |
Lang, M | 1 |
Baumgartner, M | 1 |
Evstatiev, R | 1 |
Gasche, C | 1 |
Girot, P | 1 |
Le Berre, C | 1 |
De Maissin, A | 1 |
Freyssinet, M | 1 |
Trang-Poisson, C | 1 |
Bourreille, A | 1 |
Lukáš, K | 1 |
Mandys, V | 1 |
Feuerstein, JD | 1 |
Feuerstien, JD | 1 |
Najarian, R | 1 |
Cheifetz, AS | 1 |
Koçak, G | 1 |
Koçak, E | 1 |
Akbal, E | 1 |
Şen, H | 1 |
Erbağ, G | 1 |
Erdoğan, C | 1 |
Cheng, R | 1 |
Cooper, A | 1 |
Kench, J | 1 |
Watson, G | 1 |
Bye, W | 1 |
McNeil, C | 1 |
Shackel, N | 1 |
Imhof, L | 1 |
Meier, B | 1 |
Frei, P | 1 |
Kamarachev, J | 1 |
Kolios, A | 1 |
Navarini, AA | 1 |
Contassot, E | 1 |
French, LE | 1 |
Myrelid, P | 1 |
Salim, SY | 1 |
Darby, T | 1 |
Almer, S | 1 |
Melgar, S | 1 |
Andersson, P | 1 |
Söderholm, JD | 1 |
Quaglio, AE | 2 |
Castilho, AC | 2 |
Di Stasi, LC | 2 |
Karoui, S | 1 |
Djebbi, S | 1 |
Belkhodja, A | 1 |
Boubaker, J | 1 |
Filali, A | 1 |
D'Haens, GR | 1 |
Panaccione, R | 1 |
Higgins, PD | 1 |
Vermeire, S | 1 |
Gassull, M | 1 |
Chowers, Y | 1 |
Hanauer, SB | 1 |
Herfarth, H | 1 |
Hommes, DW | 1 |
Kamm, M | 1 |
Löfberg, R | 1 |
Quary, A | 1 |
Sands, B | 1 |
Sood, A | 1 |
Watermeyer, G | 1 |
Watermayer, G | 1 |
Lashner, B | 1 |
Lémann, M | 1 |
Plevy, S | 1 |
Reinisch, W | 1 |
Schreiber, S | 1 |
Siegel, C | 1 |
Targan, S | 1 |
Watanabe, M | 1 |
Feagan, B | 1 |
Sandborn, WJ | 2 |
Colombel, JF | 1 |
Travis, S | 1 |
Kverka, M | 1 |
Rossmann, P | 1 |
Tlaskalova-Hogenova, H | 1 |
Klimesova, K | 1 |
de Boer, NK | 1 |
Vos, RM | 1 |
Lukas, M | 1 |
Mulder, CJ | 1 |
Hashash, JG | 1 |
Refaat, M | 1 |
Abdulbaki, A | 1 |
Aoun, EG | 1 |
Baidoo, L | 1 |
Hilsden, RJ | 1 |
Verhoef, MJ | 1 |
Best, A | 1 |
Pocobelli, G | 1 |
KIRSNER, JB | 1 |
Batra, AK | 1 |
Levey, JM | 1 |
Trister, J | 1 |
Patwardhan, R | 1 |
Zanditenas, D | 1 |
Hagège, H | 1 |
Rosa, I | 1 |
Cattan, P | 1 |
Ratel-Saby, S | 1 |
Lons, T | 1 |
Chousterman, M | 1 |
Pozler, O | 1 |
Maly, J | 1 |
Bonova, O | 1 |
Dedek, P | 1 |
Frühauf, P | 1 |
Havlickova, A | 1 |
Janatova, T | 1 |
Jimramovsky, F | 1 |
Klimova, L | 1 |
Klusacek, D | 1 |
Kocourkova, D | 1 |
Kolek, A | 1 |
Kotalova, R | 1 |
Marx, D | 1 |
Nevoral, J | 1 |
Petro, R | 1 |
Petru, O | 1 |
Plasilova, I | 1 |
Seidl, Z | 1 |
Sekyrova, I | 1 |
Semendak, N | 1 |
Schreierova, I | 1 |
Stanek, J | 1 |
Sykora, J | 1 |
Sulakova, A | 1 |
Toukalkova, L | 1 |
Travnickova, R | 1 |
Volf, V | 1 |
Zahradnicek, L | 1 |
Zenisková, I | 1 |
Radhakrishnan, KR | 1 |
Kay, M | 1 |
Wyllie, R | 1 |
Hashkes, PJ | 1 |
Swidsinski, A | 1 |
Loening-Baucke, V | 1 |
Bengmark, S | 1 |
Lochs, H | 1 |
Dörffel, Y | 1 |
Bartnik, W | 1 |
Shorter, RG | 1 |
Norris, AA | 1 |
Lewis, AJ | 1 |
Zeitlin, IJ | 1 |
Gelb, A | 1 |
Zalusky, R | 1 |
Markowitz, J | 1 |
Grancher, K | 1 |
Mandel, F | 1 |
Daum, F | 1 |
Maté del Tío, M | 1 |
Peña Sánchez de Rivera, JM | 1 |
Larrauri Martínez, J | 1 |
Garcés Jiménez, MC | 1 |
Barbado Hernández, FJ | 1 |
Veldman, W | 1 |
van Beek, M | 1 |
Keuning, JJ | 1 |
Driessen, WM | 1 |
van Wijk, CA | 1 |
Mearin, ML | 1 |
van de Sluys Veer, A | 1 |
Hoogerbrugge, PM | 1 |
Weiland, HT | 1 |
Vossen, JM | 1 |
Florén, CH | 1 |
Ahrén, B | 1 |
Bengtsson, M | 1 |
Bartosik, J | 1 |
Obrant, K | 1 |
Glasbrenner, B | 1 |
Güthner, C | 1 |
Röcken, C | 1 |
Mattfeld, T | 1 |
Hetzel, W | 1 |
Adler, G | 1 |
D'Haens, G | 1 |
Geboes, K | 1 |
Rutgeerts, P | 1 |
Witte, T | 1 |
Werwitzke, S | 1 |
Schmidt, RE | 1 |
Pardi, DS | 1 |
Loftus, EV | 1 |
Tremaine, WJ | 1 |
Ben Soussan, E | 1 |
Savoye, G | 1 |
Lemoine, F | 1 |
Ducastelle, P | 1 |
Colin, R | 1 |
Vennamaneni, SR | 1 |
Bonner, GF | 1 |
Binder, V | 1 |
Munkholm, P | 1 |
Cacoub, P | 1 |
Sbaï, A | 1 |
Toan, SV | 1 |
Bellanger, J | 1 |
Hoang, C | 1 |
Godeau, P | 1 |
Piette, JC | 1 |
Eguchi, K | 1 |
Caprilli, R | 1 |
Carratù, R | 1 |
Babbini, M | 1 |
Murthy, SN | 1 |
Anania, T | 1 |
Clearfield, HR | 1 |
Arvanitakis, C | 1 |
Malek, G | 1 |
Uehling, D | 1 |
Morrissey, JF | 1 |
Miller, B | 1 |
Martini, GA | 1 |
Javett, SL | 1 |
Kavin, H | 1 |
Bremner, CG | 1 |
Schneider, J | 1 |
Levine, E | 1 |
Hinder, RA | 1 |
Müller-Wieland, K | 1 |
Vachon, A | 1 |
Tête, R | 1 |
Gauthier, J | 1 |
de Montgolfier, R | 1 |
Kressmann, P | 1 |
Aschraf, SC | 1 |
Kleine, FD | 1 |
Keitel, W | 1 |
Franke, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches[NCT03885713] | Phase 4 | 180 participants (Anticipated) | Interventional | 2019-09-10 | Recruiting | ||
Risk-stratified Randomized Controlled Trial in Paediatric Crohn Disease:Methotrexate vs Azathioprine or Adalimumab for Maintaining Remission in Patients at Low or High Risk for Aggressive Disease Course, respectively-a Treatment Strategy[NCT02852694] | Phase 4 | 312 participants (Anticipated) | Interventional | 2017-02-28 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
6 reviews available for azathioprine and Colitis
Article | Year |
---|---|
Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-Analysis.
Topics: Azathioprine; Colitis; Female; Humans; Infant, Newborn; Inflammatory Bowel Diseases; Pregnancy; Preg | 2021 |
Ipilimumab-induced toxicities and the gastroenterologist.
Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury | 2015 |
Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature.
Topics: Anti-Inflammatory Agents; Azathioprine; Colitis; Drug Eruptions; Humans; Immunosuppressive Agents; I | 2015 |
The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aza | 2011 |
[Therapeutic principles for chronic inflammatory bowel disease].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colectomy; Colitis; C | 2001 |
[What is secured in the therapy of chronic inflammatory colonic diseases?].
Topics: Administration, Topical; Amebiasis; Azathioprine; Chronic Disease; Colitis; Colitis, Ulcerative; Col | 1974 |
3 trials available for azathioprine and Colitis
Article | Year |
---|---|
[Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study].
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Azathioprine; Colitis; Female; Humans; H | 2008 |
Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine.
Topics: Adult; Azathioprine; Biopsy; Colitis; Colon; Crohn Disease; Drug Therapy, Combination; Endoscopy, Ga | 1999 |
Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report.
Topics: Acute Disease; Adolescent; Adult; Aged; Azathioprine; Biopsy; Clinical Trials as Topic; Colitis; Dru | 1975 |
47 other studies available for azathioprine and Colitis
Article | Year |
---|---|
Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study.
Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine | 2023 |
Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability.
Topics: Animals; Azathioprine; Bacteria; Biological Availability; Colitis; Immunosuppressive Agents; Inflamm | 2023 |
Gastrocolic Fistula Involving the Pancreas in a Patient With Crohn's Disease.
Topics: Adalimumab; Azathioprine; Budesonide; Colectomy; Colitis; Crohn Disease; Gastric Fistula; Humans; Il | 2019 |
Methotrexate or azathioprine-do differing rates of discontinuation settle the debate?
Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate | 2020 |
Editorial: methotrexate vs azathioprine-do differential rates of discontinuation settle the debate? Authors' reply.
Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate | 2020 |
Treatment-based risk stratification of infections in inflammatory bowel disease: A comparison between anti-tumor necrosis factor-α and nonbiological exposure in real-world setting.
Topics: Azathioprine; Colitis; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Risk Asses | 2021 |
Anti-Inflammatory Effects of
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Azathioprine; Chromatography, Liquid; Colitis; Colitis | 2020 |
Colitis as a form of presentation of eosinophilic granulomatosis with polyangiitis.
Topics: Aged; Azathioprine; Churg-Strauss Syndrome; Colitis; Colonoscopy; Female; Humans; Immunosuppressive | 2018 |
BCL-2 levels do not predict azathioprine treatment response in inflammatory bowel disease, but inhibition induces lymphocyte apoptosis and ameliorates colitis in mice.
Topics: Animals; Apoptosis; Azathioprine; Cells, Cultured; Colitis; Cytokines; Disease Models, Animal; Human | 2018 |
Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis; Epithelial Cells; Inflammat | 2019 |
Crohn's-like acute severe colitis associated with Hermansky-Pudlak syndrome: A case report.
Topics: Albinism; Azathioprine; Colitis; Colon, Sigmoid; Fatal Outcome; Female; Gastrointestinal Hemorrhage; | 2019 |
[Microscopic colitis].
Topics: Adalimumab; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; An | 2013 |
Hickam's dictum in a patient with diarrhea.
Topics: Antiviral Agents; Azathioprine; Colitis; Cytomegalovirus Infections; Diarrhea; Female; Ganciclovir; | 2013 |
Eosinophilic colitis: a rare cause of lower gastrointestinal bleeding in an elderly adult.
Topics: Aged; Azathioprine; Colitis; Colonoscopy; Eosinophilia; Female; Gastrointestinal Hemorrhage; Glucoco | 2014 |
Effects of anti-inflammatory therapy on bursting pressure of colonic anastomosis in murine dextran sulfate sodium induced colitis.
Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents; Azathioprine; Colitis; Dextran Sulfate; Di | 2015 |
Experimental evidence of MAP kinase gene expression on the response of intestinal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Colitis; Enzyme Induction; Gene Expression; Male; M | 2015 |
Experimental evidence of heparanase, Hsp70 and NF-κB gene expression on the response of anti-inflammatory drugs in TNBS-induced colonic inflammation.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Biomarkers; Colitis; Colon; Cytokines; Gene Express | 2015 |
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.
Topics: Acute Disease; Alanine Transaminase; Analysis of Variance; Animals; Apoptosis; Azathioprine; Chronic | 2011 |
Cytomegalovirus colitis.
Topics: Acyclovir; Antiviral Agents; Azathioprine; Colitis; Cytomegalovirus Infections; Female; Ganciclovir; | 2012 |
A national survey on the patterns of treatment of inflammatory bowel disease in Canada.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Azathioprine; Canada; Colitis; C | 2003 |
THE IMMUNOLOGIC RESPONSE OF THE COLON.
Topics: Allergy and Immunology; Animals, Laboratory; Antigen-Antibody Reactions; Antineoplastic Agents; Auto | 1965 |
Pyoderma gangrenosum in a patient with collagenous colitis.
Topics: Administration, Oral; Aged; Azathioprine; Colitis; Diagnosis, Differential; Diarrhea; Female; Humans | 2003 |
[Inflammatory colitis and chronic granulomatous disease, a steroid-dependent case report].
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Colitis; Granulomatous Disease, Chronic; Humans; Immun | 2004 |
Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease.
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Aminosalicylic Acids; Azathioprine; Child; Child, | 2006 |
Wegener granulomatosis mimicking inflammatory bowel disease in a pediatric patient.
Topics: Abdominal Pain; Adolescent; Antibodies, Antineutrophil Cytoplasmic; Appendectomy; Azathioprine; Biop | 2006 |
Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Bacteria; Bacterial Adhesion; Colitis; | 2007 |
[An approach to the medical management of inflammatory bowel disease (author's transl)].
Topics: Azathioprine; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Parenteral Nutrition, Total; Pred | 1981 |
Actions of anticolitic drugs on a guinea-pig model of immune colitis.
Topics: Animals; Azathioprine; Colitis; Cromolyn Sodium; Dinitrochlorobenzene; Gastrointestinal Agents; Guin | 1982 |
The use of azathiaprine and 6-mercaptopurine (6-MP) as immunosuppressive therapy in inflammatory bowel disease and its role in the etiology of lymphocytic lymphoma.
Topics: Azathioprine; Colitis; Female; Humans; Lymphoma, Non-Hodgkin; Mercaptopurine; Middle Aged | 1983 |
Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum.
Topics: Adolescent; Adult; Attitude of Health Personnel; Azathioprine; Child; Colitis; Colitis, Ulcerative; | 1993 |
[Association of cytomegalovirus colitis and the 1st episode of ulcerative colitis in an immunocompetent patient].
Topics: Adrenal Cortex Hormones; Azathioprine; Colitis; Colitis, Ulcerative; Cytomegalovirus Infections; Hum | 1996 |
Regional enteritis complicating malignant lymphoma.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti | 1996 |
Cytomegalovirus colitis and immunotherapy.
Topics: Adolescent; Angiography; Azathioprine; Biopsy; Colitis; Colon; Cytomegalovirus Infections; Female; G | 1997 |
Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine.
Topics: Absorptiometry, Photon; Adult; Aged; Azathioprine; Bone Density; Colitis; Crohn Disease; Female; Hum | 1998 |
[56-year-old patient with segmental florid colitis and colonic amyloidosis].
Topics: Amyloidosis; Azathioprine; Colitis; Colonic Diseases; Colonoscopy; Crohn Disease; Diagnosis, Differe | 1999 |
CMV complications in common variable immunodeficiency.
Topics: Adult; Antiviral Agents; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lym | 2000 |
Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Colitis; Female; Humans; Immunosuppressive Agents; Mer | 2001 |
Azathioprine as a treatment of refractory lymphocytic colitis.
Topics: Adult; Azathioprine; Chronic Disease; Colitis; Diarrhea; Female; Humans; Immunosuppressive Agents; I | 2001 |
Use of azathioprine or 6-mercaptopurine for treatment of steroid-dependent lymphocytic and collagenous colitis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Colitis; Collagen; Female; Humans; | 2001 |
[Collagenous colitis. A study of 11 cases].
Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Anemia; Anti-Inflammatory Agents; Anti-Inflammat | 2001 |
Systemic lupus erythematosus complicated by cytomegalovirus-induced hemophagocytic syndrome and colitis.
Topics: Autoimmune Diseases; Azathioprine; Colitis; Cyclophosphamide; Cytokines; Cytomegalovirus Infections; | 2002 |
Azathioprine reduces extravasation and neutrophil trafficking in immune complex-mediated inflammation in the rat colon.
Topics: Aminosalicylic Acids; Animals; Antigen-Antibody Complex; Azathioprine; Colitis; Evans Blue; Male; Me | 1991 |
Colonic complications after renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Cadaver; Colectomy; Colitis; Colon; Diarrhea; Female; Gastrointesti | 1973 |
Some aspects of Crohn's disease.
Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise | 1973 |
[Current stage of clinical aspects and therapy of colitis].
Topics: Azathioprine; Colitis; Humans; Prednisolone; Sulfonamides | 1973 |
[Favorable results of the treatment of hemorrhagic rectocolitis with azathioprine (Imuran)].
Topics: Adult; Azathioprine; Colitis; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged | 1970 |
[Therapy with immunosuppressive agents in hepatology].
Topics: Azathioprine; Colitis; Headache; Hepatitis; Humans; Leukocytes; Liver Cirrhosis; Liver Diseases; Pai | 1969 |