Page last updated: 2024-10-23

azathioprine and Colitis

azathioprine has been researched along with Colitis in 56 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy of azathioprine as maintenance therapy in acute severe colitis of Crohn's disease or ulcerative colitis after successful treatment by intravenous corticosteroids."9.13[Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study]. ( Belkhodja, A; Boubaker, J; Djebbi, S; Filali, A; Karoui, S, 2008)
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine."9.09Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999)
"A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period."9.04Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975)
"We prospectively investigated colonoscopic biopsies from five groups of 20 subjects each: patients with ulcerative or indeterminate colitis treated with azathioprine (group 1), azathioprine and 5-ASA (group 2), 5-ASA (group 3), untreated IBD (group 4), and healthy controls."7.74Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis. ( Bengmark, S; Dörffel, Y; Lochs, H; Loening-Baucke, V; Swidsinski, A, 2007)
"To investigate the efficacy of azathioprine as maintenance therapy in acute severe colitis of Crohn's disease or ulcerative colitis after successful treatment by intravenous corticosteroids."5.13[Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study]. ( Belkhodja, A; Boubaker, J; Djebbi, S; Filali, A; Karoui, S, 2008)
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine."5.09Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999)
"A double-blind therapeutic trial of azathioprine in 20 patients with acute proctocolitis was performed over a 3-month period."5.04Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report. ( Babbini, M; Caprilli, R; Carratù, R, 1975)
" We report the case of a 50-year-old patient with indeterminate colitis, presenting with a febrile diffuse papulopustular and necrotizing skin eruption that healed with significant scarring and appeared 14 days after onset of treatment with azathioprine."4.91Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature. ( Contassot, E; Frei, P; French, LE; Imhof, L; Kamarachev, J; Kolios, A; Meier, B; Navarini, AA; Rogler, G, 2015)
"IBD patients who previously failed azathioprine or mercaptopurine and initiated thioguanine were prospectively followed for 12 months starting when corticosteroid-free clinical remission was achieved (Harvey-Bradshaw Index [HBI] ≤ 4 or Simple Clinical Colitis Activity Index [SCCAI] ≤ 2)."4.31Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study. ( Boekema, P; de Boer, N; de Leest, M; Dijkstra, G; Fidder, H; Gisbertz, I; Hoentjen, F; Jharap, B; Kaplan, S; Kubben, F; Meijssen, M; Mulder, CJJ; Petrak, A; Russel, M; Schepers, F; Simsek, M; van Asseldonk, D; van Bodegraven, AA; van Boeckel, P; van de Poel, E, 2023)
"We report a case of severe colitis that led to the diagnosis of HPS, which was responsive to azathioprine and infliximab."3.91Crohn's-like acute severe colitis associated with Hermansky-Pudlak syndrome: A case report. ( Bourreille, A; De Maissin, A; Freyssinet, M; Girot, P; Le Berre, C; Trang-Poisson, C, 2019)
"We prospectively investigated colonoscopic biopsies from five groups of 20 subjects each: patients with ulcerative or indeterminate colitis treated with azathioprine (group 1), azathioprine and 5-ASA (group 2), 5-ASA (group 3), untreated IBD (group 4), and healthy controls."3.74Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis. ( Bengmark, S; Dörffel, Y; Lochs, H; Loening-Baucke, V; Swidsinski, A, 2007)
" However, the dosing and the duration of immunosuppressive therapy have not been systematically studied in the setting of treating ipilimumab-induced irAEs."2.52Ipilimumab-induced toxicities and the gastroenterologist. ( Bye, W; Cheng, R; Cooper, A; Kench, J; McNeil, C; Shackel, N; Watson, G, 2015)
"Whereas the incidence of ulcerative colitis has remained stable at around 8-9/10(5), the incidence of Crohn's disease has increased from below 1 to more than 5/10(5) per year during the last three decades."2.41[Therapeutic principles for chronic inflammatory bowel disease]. ( Binder, V; Munkholm, P, 2001)
" wexlerae colonization reduced 6-mercaptopurine (6-MP) bioavailability by enhancing selenium-dependent xanthine dehydrogenase (sd-XDH) activity."1.91Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability. ( Chen, H; Cui, Z; Fang, JY; Gao, Z; Hong, J; Hu, M; Huang, X; Ma, Y; Ning, L; Tong, T; Wang, Z; Xuan, B; Yan, Y; Zhao, Y; Zhou, YL, 2023)
"Microscopic colitis is characterized by chronic or intermittent watery diarrhoea."1.39[Microscopic colitis]. ( Lukáš, K; Mandys, V, 2013)
"Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events."1.37Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis. ( de Boer, NK; Jharap, B; Klimesova, K; Kverka, M; Lukas, M; Mulder, CJ; Rossmann, P; Tlaskalova-Hogenova, H; van Bodegraven, AA; Vos, RM, 2011)
"Diagnostic criteria for CD, ulcerative colitis (UC), and indeterminate colitis (IC) were defined."1.33Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease. ( Bonova, O; Dedek, P; Frühauf, P; Havlickova, A; Janatova, T; Jimramovsky, F; Klimova, L; Klusacek, D; Kocourkova, D; Kolek, A; Kotalova, R; Maly, J; Marx, D; Nevoral, J; Petro, R; Petru, O; Plasilova, I; Pozler, O; Schreierova, I; Seidl, Z; Sekyrova, I; Semendak, N; Stanek, J; Sulakova, A; Sykora, J; Toukalkova, L; Travnickova, R; Volf, V; Zahradnicek, L; Zenisková, I, 2006)
"6-mercaptopurine/azathioprine was used by 24% of patients with Crohn's disease and 12% of patients with ulcerative colitis (95% CI for the difference: 8."1.32A national survey on the patterns of treatment of inflammatory bowel disease in Canada. ( Best, A; Hilsden, RJ; Pocobelli, G; Verhoef, MJ, 2003)
"Collagenous colitis is one of the microscopic colitides, which are thought to be on the same spectrum of disease as Crohn's disease and ulcerative colitis."1.32Pyoderma gangrenosum in a patient with collagenous colitis. ( Batra, AK; Levey, JM; Patwardhan, R; Trister, J, 2003)
"An exacerbation of the myelitis, retinitis, encephalitis and colitis was observed and a cytomegalovirus infection diagnosed."1.31CMV complications in common variable immunodeficiency. ( Schmidt, RE; Werwitzke, S; Witte, T, 2000)
"To ascertain whether patients with Crohn's disease treated with azathioprine maintained bone mineral mass better than patients treated with steroids alone."1.30Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine. ( Ahrén, B; Bartosik, J; Bengtsson, M; Florén, CH; Obrant, K, 1998)
"Eighty-one percent had Crohn's disease, 8% ulcerative colitis, and 11% indeterminant colitis."1.29Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum. ( Daum, F; Grancher, K; Mandel, F; Markowitz, J, 1993)
"Azathioprine (AZ) has been used in the treatment of refractory inflammatory bowel disease."1.28Azathioprine reduces extravasation and neutrophil trafficking in immune complex-mediated inflammation in the rat colon. ( Anania, T; Clearfield, HR; Murthy, SN, 1991)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199011 (19.64)18.7374
1990's8 (14.29)18.2507
2000's14 (25.00)29.6817
2010's16 (28.57)24.3611
2020's7 (12.50)2.80

Authors

AuthorsStudies
Simsek, M1
Schepers, F1
Kaplan, S1
van Asseldonk, D1
van Boeckel, P1
Boekema, P1
Dijkstra, G1
Fidder, H1
Gisbertz, I1
Hoentjen, F1
Jharap, B2
Kubben, F1
de Leest, M1
Meijssen, M1
Petrak, A1
van de Poel, E1
Russel, M1
van Bodegraven, AA2
Mulder, CJJ1
de Boer, N1
Yan, Y1
Wang, Z1
Zhou, YL1
Gao, Z1
Ning, L1
Zhao, Y1
Xuan, B1
Ma, Y1
Tong, T1
Huang, X1
Hu, M1
Fang, JY1
Cui, Z1
Chen, H1
Hong, J1
Booth, AT1
Forster, E1
Curran, T1
George, V1
Zhang, Y1
Li, D1
Guo, H1
Wang, W1
Li, X1
Shen, S1
Fraser, AG1
Vasudevan, A1
Con, D1
Nicolaides, S1
van Langenberg, DR1
Imperatore, N1
Foggia, M1
Patturelli, M1
Rispo, A1
Calabrese, G1
Testa, A1
Pellegrini, L1
Tosone, G1
Di Luna, I1
Nardone, OM1
Ricciolino, S1
Castiglione, F1
Lin, G1
Li, M1
Xu, N1
Wu, X1
Liu, J1
Wu, Y1
Zhang, Q1
Cai, J1
Gao, C1
Su, Z1
Ameneiros-Lago, E1
Pérez-Valcarcel, J1
Fernández-Fernández, FJ1
Caínzos-Romero, T1
Weder, B1
Mozaffari, M1
Biedermann, L1
Mamie, C1
Moncsek, A1
Wang, L1
Clarke, SH1
Rogler, G2
McRae, BL1
Graff, CL1
Ruiz, PA1
Hausmann, M1
Khare, V1
Krnjic, A1
Frick, A1
Gmainer, C1
Asboth, M1
Jimenez, K1
Lang, M1
Baumgartner, M1
Evstatiev, R1
Gasche, C1
Girot, P1
Le Berre, C1
De Maissin, A1
Freyssinet, M1
Trang-Poisson, C1
Bourreille, A1
Lukáš, K1
Mandys, V1
Feuerstein, JD1
Feuerstien, JD1
Najarian, R1
Cheifetz, AS1
Koçak, G1
Koçak, E1
Akbal, E1
Şen, H1
Erbağ, G1
Erdoğan, C1
Cheng, R1
Cooper, A1
Kench, J1
Watson, G1
Bye, W1
McNeil, C1
Shackel, N1
Imhof, L1
Meier, B1
Frei, P1
Kamarachev, J1
Kolios, A1
Navarini, AA1
Contassot, E1
French, LE1
Myrelid, P1
Salim, SY1
Darby, T1
Almer, S1
Melgar, S1
Andersson, P1
Söderholm, JD1
Quaglio, AE2
Castilho, AC2
Di Stasi, LC2
Karoui, S1
Djebbi, S1
Belkhodja, A1
Boubaker, J1
Filali, A1
D'Haens, GR1
Panaccione, R1
Higgins, PD1
Vermeire, S1
Gassull, M1
Chowers, Y1
Hanauer, SB1
Herfarth, H1
Hommes, DW1
Kamm, M1
Löfberg, R1
Quary, A1
Sands, B1
Sood, A1
Watermeyer, G1
Watermayer, G1
Lashner, B1
Lémann, M1
Plevy, S1
Reinisch, W1
Schreiber, S1
Siegel, C1
Targan, S1
Watanabe, M1
Feagan, B1
Sandborn, WJ2
Colombel, JF1
Travis, S1
Kverka, M1
Rossmann, P1
Tlaskalova-Hogenova, H1
Klimesova, K1
de Boer, NK1
Vos, RM1
Lukas, M1
Mulder, CJ1
Hashash, JG1
Refaat, M1
Abdulbaki, A1
Aoun, EG1
Baidoo, L1
Hilsden, RJ1
Verhoef, MJ1
Best, A1
Pocobelli, G1
KIRSNER, JB1
Batra, AK1
Levey, JM1
Trister, J1
Patwardhan, R1
Zanditenas, D1
Hagège, H1
Rosa, I1
Cattan, P1
Ratel-Saby, S1
Lons, T1
Chousterman, M1
Pozler, O1
Maly, J1
Bonova, O1
Dedek, P1
Frühauf, P1
Havlickova, A1
Janatova, T1
Jimramovsky, F1
Klimova, L1
Klusacek, D1
Kocourkova, D1
Kolek, A1
Kotalova, R1
Marx, D1
Nevoral, J1
Petro, R1
Petru, O1
Plasilova, I1
Seidl, Z1
Sekyrova, I1
Semendak, N1
Schreierova, I1
Stanek, J1
Sykora, J1
Sulakova, A1
Toukalkova, L1
Travnickova, R1
Volf, V1
Zahradnicek, L1
Zenisková, I1
Radhakrishnan, KR1
Kay, M1
Wyllie, R1
Hashkes, PJ1
Swidsinski, A1
Loening-Baucke, V1
Bengmark, S1
Lochs, H1
Dörffel, Y1
Bartnik, W1
Shorter, RG1
Norris, AA1
Lewis, AJ1
Zeitlin, IJ1
Gelb, A1
Zalusky, R1
Markowitz, J1
Grancher, K1
Mandel, F1
Daum, F1
Maté del Tío, M1
Peña Sánchez de Rivera, JM1
Larrauri Martínez, J1
Garcés Jiménez, MC1
Barbado Hernández, FJ1
Veldman, W1
van Beek, M1
Keuning, JJ1
Driessen, WM1
van Wijk, CA1
Mearin, ML1
van de Sluys Veer, A1
Hoogerbrugge, PM1
Weiland, HT1
Vossen, JM1
Florén, CH1
Ahrén, B1
Bengtsson, M1
Bartosik, J1
Obrant, K1
Glasbrenner, B1
Güthner, C1
Röcken, C1
Mattfeld, T1
Hetzel, W1
Adler, G1
D'Haens, G1
Geboes, K1
Rutgeerts, P1
Witte, T1
Werwitzke, S1
Schmidt, RE1
Pardi, DS1
Loftus, EV1
Tremaine, WJ1
Ben Soussan, E1
Savoye, G1
Lemoine, F1
Ducastelle, P1
Colin, R1
Vennamaneni, SR1
Bonner, GF1
Binder, V1
Munkholm, P1
Cacoub, P1
Sbaï, A1
Toan, SV1
Bellanger, J1
Hoang, C1
Godeau, P1
Piette, JC1
Eguchi, K1
Caprilli, R1
Carratù, R1
Babbini, M1
Murthy, SN1
Anania, T1
Clearfield, HR1
Arvanitakis, C1
Malek, G1
Uehling, D1
Morrissey, JF1
Miller, B1
Martini, GA1
Javett, SL1
Kavin, H1
Bremner, CG1
Schneider, J1
Levine, E1
Hinder, RA1
Müller-Wieland, K1
Vachon, A1
Tête, R1
Gauthier, J1
de Montgolfier, R1
Kressmann, P1
Aschraf, SC1
Kleine, FD1
Keitel, W1
Franke, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches[NCT03885713]Phase 4180 participants (Anticipated)Interventional2019-09-10Recruiting
Risk-stratified Randomized Controlled Trial in Paediatric Crohn Disease:Methotrexate vs Azathioprine or Adalimumab for Maintaining Remission in Patients at Low or High Risk for Aggressive Disease Course, respectively-a Treatment Strategy[NCT02852694]Phase 4312 participants (Anticipated)Interventional2017-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for azathioprine and Colitis

ArticleYear
Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-Analysis.
    Current pharmaceutical design, 2021, Volume: 27, Issue:19

    Topics: Azathioprine; Colitis; Female; Humans; Infant, Newborn; Inflammatory Bowel Diseases; Pregnancy; Preg

2021
Ipilimumab-induced toxicities and the gastroenterologist.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:4

    Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury

2015
Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature.
    Dermatology (Basel, Switzerland), 2015, Volume: 230, Issue:4

    Topics: Anti-Inflammatory Agents; Azathioprine; Colitis; Drug Eruptions; Humans; Immunosuppressive Agents; I

2015
The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?
    The American journal of gastroenterology, 2011, Volume: 106, Issue:2

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aza

2011
[Therapeutic principles for chronic inflammatory bowel disease].
    Ugeskrift for laeger, 2001, Jan-01, Volume: 163, Issue:1

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colectomy; Colitis; C

2001
[What is secured in the therapy of chronic inflammatory colonic diseases?].
    Der Internist, 1974, Volume: 15, Issue:12

    Topics: Administration, Topical; Amebiasis; Azathioprine; Chronic Disease; Colitis; Colitis, Ulcerative; Col

1974

Trials

3 trials available for azathioprine and Colitis

ArticleYear
[Maintenance therapy by azathioprine after successful treatment by intravenous corticosteroid in acute severe colitis. An open prospective study].
    La Tunisie medicale, 2008, Volume: 86, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Azathioprine; Colitis; Female; Humans; H

2008
Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine.
    Gastrointestinal endoscopy, 1999, Volume: 50, Issue:5

    Topics: Adult; Azathioprine; Biopsy; Colitis; Colon; Crohn Disease; Drug Therapy, Combination; Endoscopy, Ga

1999
Double-blind comparison of the effectiveness of azathioprine and sulfasalazine in idiopathic proctocolitis. Preliminary report.
    The American journal of digestive diseases, 1975, Volume: 20, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Azathioprine; Biopsy; Clinical Trials as Topic; Colitis; Dru

1975

Other Studies

47 other studies available for azathioprine and Colitis

ArticleYear
Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study.
    Journal of Crohn's & colitis, 2023, Jun-16, Volume: 17, Issue:6

    Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine

2023
Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability.
    Cell reports. Medicine, 2023, 08-15, Volume: 4, Issue:8

    Topics: Animals; Azathioprine; Bacteria; Biological Availability; Colitis; Immunosuppressive Agents; Inflamm

2023
Gastrocolic Fistula Involving the Pancreas in a Patient With Crohn's Disease.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:11

    Topics: Adalimumab; Azathioprine; Budesonide; Colectomy; Colitis; Crohn Disease; Gastric Fistula; Humans; Il

2019
Methotrexate or azathioprine-do differing rates of discontinuation settle the debate?
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:9

    Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

2020
Editorial: methotrexate vs azathioprine-do differential rates of discontinuation settle the debate? Authors' reply.
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:9

    Topics: Azathioprine; Colitis; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Methotrexate

2020
Treatment-based risk stratification of infections in inflammatory bowel disease: A comparison between anti-tumor necrosis factor-α and nonbiological exposure in real-world setting.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:7

    Topics: Azathioprine; Colitis; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methotrexate; Risk Asses

2021
Anti-Inflammatory Effects of
    BioMed research international, 2020, Volume: 2020

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Azathioprine; Chromatography, Liquid; Colitis; Colitis

2020
Colitis as a form of presentation of eosinophilic granulomatosis with polyangiitis.
    Gastroenterologia y hepatologia, 2018, Volume: 41, Issue:5

    Topics: Aged; Azathioprine; Churg-Strauss Syndrome; Colitis; Colonoscopy; Female; Humans; Immunosuppressive

2018
BCL-2 levels do not predict azathioprine treatment response in inflammatory bowel disease, but inhibition induces lymphocyte apoptosis and ameliorates colitis in mice.
    Clinical and experimental immunology, 2018, Volume: 193, Issue:3

    Topics: Animals; Apoptosis; Azathioprine; Cells, Cultured; Colitis; Cytokines; Disease Models, Animal; Human

2018
Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation.
    Scientific reports, 2019, 02-26, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis; Epithelial Cells; Inflammat

2019
Crohn's-like acute severe colitis associated with Hermansky-Pudlak syndrome: A case report.
    World journal of gastroenterology, 2019, Feb-28, Volume: 25, Issue:8

    Topics: Albinism; Azathioprine; Colitis; Colon, Sigmoid; Fatal Outcome; Female; Gastrointestinal Hemorrhage;

2019
[Microscopic colitis].
    Casopis lekaru ceskych, 2013, Volume: 152, Issue:2

    Topics: Adalimumab; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; An

2013
Hickam's dictum in a patient with diarrhea.
    Gastroenterology, 2013, Volume: 145, Issue:5

    Topics: Antiviral Agents; Azathioprine; Colitis; Cytomegalovirus Infections; Diarrhea; Female; Ganciclovir;

2013
Eosinophilic colitis: a rare cause of lower gastrointestinal bleeding in an elderly adult.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:10

    Topics: Aged; Azathioprine; Colitis; Colonoscopy; Eosinophilia; Female; Gastrointestinal Hemorrhage; Glucoco

2014
Effects of anti-inflammatory therapy on bursting pressure of colonic anastomosis in murine dextran sulfate sodium induced colitis.
    Scandinavian journal of gastroenterology, 2015, Volume: 50, Issue:8

    Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents; Azathioprine; Colitis; Dextran Sulfate; Di

2015
Experimental evidence of MAP kinase gene expression on the response of intestinal anti-inflammatory drugs.
    Life sciences, 2015, Sep-01, Volume: 136

    Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Colitis; Enzyme Induction; Gene Expression; Male; M

2015
Experimental evidence of heparanase, Hsp70 and NF-κB gene expression on the response of anti-inflammatory drugs in TNBS-induced colonic inflammation.
    Life sciences, 2015, Nov-15, Volume: 141

    Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Biomarkers; Colitis; Colon; Cytokines; Gene Express

2015
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.
    BMC gastroenterology, 2011, May-05, Volume: 11

    Topics: Acute Disease; Alanine Transaminase; Analysis of Variance; Animals; Apoptosis; Azathioprine; Chronic

2011
Cytomegalovirus colitis.
    Cleveland Clinic journal of medicine, 2012, Volume: 79, Issue:1

    Topics: Acyclovir; Antiviral Agents; Azathioprine; Colitis; Cytomegalovirus Infections; Female; Ganciclovir;

2012
A national survey on the patterns of treatment of inflammatory bowel disease in Canada.
    BMC gastroenterology, 2003, Jun-05, Volume: 3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Azathioprine; Canada; Colitis; C

2003
THE IMMUNOLOGIC RESPONSE OF THE COLON.
    JAMA, 1965, Mar-08, Volume: 191

    Topics: Allergy and Immunology; Animals, Laboratory; Antigen-Antibody Reactions; Antineoplastic Agents; Auto

1965
Pyoderma gangrenosum in a patient with collagenous colitis.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:5 Suppl

    Topics: Administration, Oral; Aged; Azathioprine; Colitis; Diagnosis, Differential; Diarrhea; Female; Humans

2003
[Inflammatory colitis and chronic granulomatous disease, a steroid-dependent case report].
    Gastroenterologie clinique et biologique, 2004, Volume: 28, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Colitis; Granulomatous Disease, Chronic; Humans; Immun

2004
Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 42, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Aminosalicylic Acids; Azathioprine; Child; Child,

2006
Wegener granulomatosis mimicking inflammatory bowel disease in a pediatric patient.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 43, Issue:3

    Topics: Abdominal Pain; Adolescent; Antibodies, Antineutrophil Cytoplasmic; Appendectomy; Azathioprine; Biop

2006
Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitis.
    Inflammatory bowel diseases, 2007, Volume: 13, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Bacteria; Bacterial Adhesion; Colitis;

2007
[An approach to the medical management of inflammatory bowel disease (author's transl)].
    Przeglad lekarski, 1981, Volume: 38, Issue:6

    Topics: Azathioprine; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Parenteral Nutrition, Total; Pred

1981
Actions of anticolitic drugs on a guinea-pig model of immune colitis.
    Agents and actions, 1982, Volume: 12, Issue:1-2

    Topics: Animals; Azathioprine; Colitis; Cromolyn Sodium; Dinitrochlorobenzene; Gastrointestinal Agents; Guin

1982
The use of azathiaprine and 6-mercaptopurine (6-MP) as immunosuppressive therapy in inflammatory bowel disease and its role in the etiology of lymphocytic lymphoma.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:5

    Topics: Azathioprine; Colitis; Female; Humans; Lymphoma, Non-Hodgkin; Mercaptopurine; Middle Aged

1983
Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:1

    Topics: Adolescent; Adult; Attitude of Health Personnel; Azathioprine; Child; Colitis; Colitis, Ulcerative;

1993
[Association of cytomegalovirus colitis and the 1st episode of ulcerative colitis in an immunocompetent patient].
    Gastroenterologia y hepatologia, 1996, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Azathioprine; Colitis; Colitis, Ulcerative; Cytomegalovirus Infections; Hum

1996
Regional enteritis complicating malignant lymphoma.
    The Netherlands journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti

1996
Cytomegalovirus colitis and immunotherapy.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:5

    Topics: Adolescent; Angiography; Azathioprine; Biopsy; Colitis; Colon; Cytomegalovirus Infections; Female; G

1997
Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine.
    Journal of internal medicine, 1998, Volume: 243, Issue:2

    Topics: Absorptiometry, Photon; Adult; Aged; Azathioprine; Bone Density; Colitis; Crohn Disease; Female; Hum

1998
[56-year-old patient with segmental florid colitis and colonic amyloidosis].
    Der Internist, 1999, Volume: 40, Issue:6

    Topics: Amyloidosis; Azathioprine; Colitis; Colonic Diseases; Colonoscopy; Crohn Disease; Diagnosis, Differe

1999
CMV complications in common variable immunodeficiency.
    Immunobiology, 2000, Volume: 202, Issue:2

    Topics: Adult; Antiviral Agents; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lym

2000
Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine.
    Gastroenterology, 2001, Volume: 120, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Colitis; Female; Humans; Immunosuppressive Agents; Mer

2001
Azathioprine as a treatment of refractory lymphocytic colitis.
    European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:4

    Topics: Adult; Azathioprine; Chronic Disease; Colitis; Diarrhea; Female; Humans; Immunosuppressive Agents; I

2001
Use of azathioprine or 6-mercaptopurine for treatment of steroid-dependent lymphocytic and collagenous colitis.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Colitis; Collagen; Female; Humans;

2001
[Collagenous colitis. A study of 11 cases].
    Annales de medecine interne, 2001, Volume: 152, Issue:5

    Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Anemia; Anti-Inflammatory Agents; Anti-Inflammat

2001
Systemic lupus erythematosus complicated by cytomegalovirus-induced hemophagocytic syndrome and colitis.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:2

    Topics: Autoimmune Diseases; Azathioprine; Colitis; Cyclophosphamide; Cytokines; Cytomegalovirus Infections;

2002
Azathioprine reduces extravasation and neutrophil trafficking in immune complex-mediated inflammation in the rat colon.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Aminosalicylic Acids; Animals; Antigen-Antibody Complex; Azathioprine; Colitis; Evans Blue; Male; Me

1991
Colonic complications after renal transplantation.
    Gastroenterology, 1973, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Azathioprine; Cadaver; Colectomy; Colitis; Colon; Diarrhea; Female; Gastrointesti

1973
Some aspects of Crohn's disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-11, Volume: 47, Issue:31

    Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise

1973
[Current stage of clinical aspects and therapy of colitis].
    Die Medizinische Welt, 1973, Dec-14, Volume: 24, Issue:50

    Topics: Azathioprine; Colitis; Humans; Prednisolone; Sulfonamides

1973
[Favorable results of the treatment of hemorrhagic rectocolitis with azathioprine (Imuran)].
    Journal de medecine de Lyon, 1970, Jan-20, Volume: 51, Issue:179

    Topics: Adult; Azathioprine; Colitis; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged

1970
[Therapy with immunosuppressive agents in hepatology].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jun-15, Volume: 24, Issue:12

    Topics: Azathioprine; Colitis; Headache; Hepatitis; Humans; Leukocytes; Liver Cirrhosis; Liver Diseases; Pai

1969