azathioprine has been researched along with Cochlear Hearing Loss in 14 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dosage was further reduced by adding methotrexate at 7." | 7.01 | Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review. ( Huang, KH; Lin, CD; Lin, HC; Wu, PC, 2023) |
| "Sclerosing sialadenitis occurred before AIP, whereas autoimmune sensorineural hearing loss, allergic purpura and endocapillary proliferative glomerulonephritis occurred after AIP." | 5.35 | Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy. ( Ando, T; Hayashi, K; Joh, T; Miyabe, K; Naitoh, I; Nakazawa, T; Ohara, H; Okumura, F; Sano, H; Takahashi, S; Tanaka, H; Yoshida, M, 2009) |
| " The dosage was further reduced by adding methotrexate at 7." | 3.01 | Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review. ( Huang, KH; Lin, CD; Lin, HC; Wu, PC, 2023) |
| "Atypical Cogan's syndrome is more commonly associated with systemic manifestations than typical disease, and may be refractory to immunosuppressive treatment." | 2.45 | Cogan's syndrome: present and future directions. ( Harney, S; Molloy, M; Murphy, G; Shanahan, F; Sullivan, MO, 2009) |
| "Sensorineural hearing loss has been described in autoimmune disorders but is rare." | 2.44 | Sensorineural hearing loss in systemic lupus erythematosus: case report and literature review. ( Khalidi, NA; Rebello, R; Robertson, DD, 2008) |
| " The administration of intratympanic infliximab is an effective and safe technique." | 1.56 | Intratympanic infliximab is a safe and effective rescue therapy for refractory immune-mediated hearing loss. ( García-Fernández, A; Mata-Castro, N; Sanz-López, L; Varillas-Delgado, D, 2020) |
| "Sensorineural hearing loss is significantly more prevalent in refractory rheumatoid arthritis patients." | 1.46 | Hearing status in patients with rheumatoid arthritis. ( Ahmadzadeh, A; Amini, E; Daneshi, A; Daraei, M; Jalessi, M; Peyvandi, AA; Ranjbar, LA, 2017) |
| " Systemic treatment usually begins with high dosage corticosteroids." | 1.42 | Atypical Cogan's syndrome: a case report and summary of current treatment options. ( Jančatová, D; Komínek, P; Matoušek, P; Zeleník, K, 2015) |
| "Sclerosing sialadenitis occurred before AIP, whereas autoimmune sensorineural hearing loss, allergic purpura and endocapillary proliferative glomerulonephritis occurred after AIP." | 1.35 | Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy. ( Ando, T; Hayashi, K; Joh, T; Miyabe, K; Naitoh, I; Nakazawa, T; Ohara, H; Okumura, F; Sano, H; Takahashi, S; Tanaka, H; Yoshida, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, KH | 1 |
| Lin, HC | 1 |
| Lin, CD | 1 |
| Wu, PC | 1 |
| Mata-Castro, N | 1 |
| Sanz-López, L | 1 |
| Varillas-Delgado, D | 1 |
| García-Fernández, A | 1 |
| Ahmadzadeh, A | 1 |
| Daraei, M | 1 |
| Jalessi, M | 1 |
| Peyvandi, AA | 1 |
| Amini, E | 1 |
| Ranjbar, LA | 1 |
| Daneshi, A | 1 |
| Bloom, JL | 1 |
| Lin, C | 1 |
| Imundo, L | 1 |
| Guthery, S | 1 |
| Stepenaskie, S | 1 |
| Galambos, C | 1 |
| Lowichik, A | 1 |
| Bohnsack, JF | 1 |
| Jenkinson, PW | 1 |
| Syed, MI | 1 |
| Mcclymont, L | 1 |
| Jančatová, D | 1 |
| Zeleník, K | 1 |
| Komínek, P | 1 |
| Matoušek, P | 1 |
| Postelmans, L | 1 |
| Willermain, F | 1 |
| Guillaume, MP | 1 |
| Libert, M | 1 |
| Hermanus, N | 1 |
| Vannechel, C | 1 |
| Verougstraete, C | 1 |
| Murphy, G | 1 |
| Sullivan, MO | 1 |
| Shanahan, F | 1 |
| Harney, S | 1 |
| Molloy, M | 1 |
| Naitoh, I | 1 |
| Nakazawa, T | 1 |
| Ohara, H | 1 |
| Sano, H | 1 |
| Ando, T | 1 |
| Hayashi, K | 1 |
| Tanaka, H | 1 |
| Okumura, F | 1 |
| Miyabe, K | 1 |
| Yoshida, M | 1 |
| Takahashi, S | 1 |
| Joh, T | 1 |
| McCarthy, EM | 1 |
| Cunnane, G | 1 |
| Broughton, SS | 1 |
| Meyerhoff, WE | 1 |
| Cohen, SB | 1 |
| Khalidi, NA | 1 |
| Rebello, R | 1 |
| Robertson, DD | 1 |
| Lasak, JM | 1 |
| Sataloff, RT | 1 |
| Hawkshaw, M | 1 |
| Carey, TE | 1 |
| Lyons, KM | 1 |
| Spiegel, JR | 1 |
| Benitez, JT | 1 |
| Arsenault, MD | 1 |
| Licht, JM | 1 |
| Cohen, SD | 1 |
| Greenberg, RV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Trial of Rilonacept for Treatment of Autoimmune Neurosensory Hearing Loss[NCT02828033] | Early Phase 1 | 10 participants (Anticipated) | Interventional | 2017-02-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Cochlear Hearing Loss
| Article | Year |
|---|---|
Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review.
Topics: Adrenal Cortex Hormones; Adult; Autoimmune Diseases; Azathioprine; Female; Hearing Loss, Sensorineur | 2023 |
Cogan's syndrome: present and future directions.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Dose-Response Relationship, Drug; Fatal Outcome; Femal | 2009 |
Sensorineural hearing loss in systemic lupus erythematosus: case report and literature review.
Topics: Adult; Anticoagulants; Antimetabolites; Audiometry, Pure-Tone; Azathioprine; Drug Therapy, Combinati | 2008 |
11 other studies available for azathioprine and Cochlear Hearing Loss
| Article | Year |
|---|---|
Intratympanic infliximab is a safe and effective rescue therapy for refractory immune-mediated hearing loss.
Topics: Administration, Oral; Adult; Aged; Auditory Threshold; Azathioprine; Chronic Disease; Female; Hearin | 2020 |
Hearing status in patients with rheumatoid arthritis.
Topics: Acoustic Impedance Tests; Adult; Arthritis, Rheumatoid; Audiometry, Pure-Tone; Azathioprine; Cochlea | 2017 |
H syndrome: 5 new cases from the United States with novel features and responses to therapy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Child; Child, Preschool; Contracture; Diagno | 2017 |
Progressive, reversible sensorineural hearing loss caused by azathioprine.
Topics: Audiometry, Pure-Tone; Azathioprine; Female; Hearing Loss, Sensorineural; Humans; Middle Aged | 2014 |
Atypical Cogan's syndrome: a case report and summary of current treatment options.
Topics: Adolescent; Azathioprine; Cogan Syndrome; Female; Glucocorticoids; Hearing Loss, Bilateral; Hearing | 2015 |
Retinal arterio-arterial collaterals in SUSAC syndrome.
Topics: Adult; Azathioprine; Brain; Cerebrovascular Disorders; Collateral Circulation; Corpus Callosum; Cycl | 2008 |
Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination; Female; Heari | 2009 |
Treatment of relapsing polychondritis in the era of biological agents.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Aortic Valve; | 2010 |
Immune-mediated inner ear disease: 10-year experience.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Cyclopho | 2004 |
Autoimmune inner ear disease: steroid and cytotoxic drug therapy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathiopri | 2001 |
Evidence of central vestibulo-auditory dysfunction in atypical Cogan's syndrome: a case report.
Topics: Adult; Audiometry; Auditory Diseases, Central; Azathioprine; Drug Therapy, Combination; Electronysta | 1990 |