azathioprine has been researched along with Chronic Progressive Multiple Sclerosis in 9 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is a purine analogue which has been used in the treatment of multiple sclerosis (MS) for over 30 years." | 2.46 | [Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?]. ( Schmidt, S, 2010) |
| "Forty-seven patients with secondary progressive multiple sclerosis and seven others with primary progressive received monthly infusions of cyclophosphamide (750mg/m2) and methylprednisolone (500mg)." | 1.32 | [Treatment of progressive multiple sclerosis with monthly pulsed cyclophosphamide-methylprednisolone: predictive factors of treatment response]. ( Bourg, V; Chanalet, S; Chatel, M; Delmont, E; Lebrun, C; Soriani, MH, 2004) |
| " Most clinics use intravenous steroids for treating relapses, although with different dosing regimens." | 1.30 | Current status of multiple sclerosis therapy in Germany: a national survey. ( Berenbeck, C; Buhmann, C; Emskotter, T; Hadji-Abdolrahim, B; Hauer, S; Heesen, C, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, S | 1 |
| Fernández, O | 1 |
| Guerrero, M | 1 |
| Mayorga, C | 1 |
| Muñoz, L | 1 |
| Leán, A | 1 |
| Luque, G | 1 |
| Hervás, M | 1 |
| Fernández, V | 1 |
| Capdevila, A | 1 |
| de Ramón, E | 1 |
| Kieseier, BC | 1 |
| Hartung, HP | 1 |
| Lacour, A | 1 |
| De Seze, J | 1 |
| Revenco, E | 1 |
| Lebrun, C | 2 |
| Masmoudi, K | 1 |
| Vidry, E | 1 |
| Rumbach, L | 1 |
| Chatel, M | 2 |
| Verier, A | 1 |
| Vermersch, P | 1 |
| Delmont, E | 1 |
| Chanalet, S | 1 |
| Bourg, V | 1 |
| Soriani, MH | 1 |
| La Mantia, L | 1 |
| D'Amico, D | 1 |
| Rigamonti, A | 1 |
| Mascoli, N | 1 |
| Bussone, G | 1 |
| Milanese, C | 1 |
| Yerdelen, D | 1 |
| Karatas, M | 1 |
| Goksel, B | 1 |
| Yildirim, T | 1 |
| Heesen, C | 1 |
| Hauer, S | 1 |
| Hadji-Abdolrahim, B | 1 |
| Berenbeck, C | 1 |
| Buhmann, C | 1 |
| Emskotter, T | 1 |
| Lublin, FD | 1 |
3 reviews available for azathioprine and Chronic Progressive Multiple Sclerosis
| Article | Year |
|---|---|
[Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?].
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Animals; Azathioprine; Cladribine; Cl | 2010 |
Current disease-modifying therapies in multiple sclerosis.
Topics: Adjuvants, Immunologic; Analgesics; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azath | 2003 |
Therapeutic approaches to secondary progressive multiple sclerosis.
Topics: Anti-Inflammatory Agents; Azathioprine; Bone Marrow Transplantation; Cladribine; Clinical Trials as | 2002 |
1 trial available for azathioprine and Chronic Progressive Multiple Sclerosis
| Article | Year |
|---|---|
Interferon treatment may trigger primary headaches in multiple sclerosis patients.
Topics: Adjuvants, Immunologic; Adult; Aged; Azathioprine; Female; Glatiramer Acetate; Headache; Humans; Imm | 2006 |
5 other studies available for azathioprine and Chronic Progressive Multiple Sclerosis
| Article | Year |
|---|---|
Combination therapy with interferon beta-1b and azathioprine in secondary progressive multiple sclerosis. A two-year pilot study.
Topics: Adjuvants, Immunologic; Adult; Azathioprine; Disease Progression; Drug Therapy, Combination; Female; | 2002 |
Acute aphasia in multiple sclerosis: A multicenter study of 22 patients.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Aphasia; Azathioprine; Brain; Cohort Studies; Comorb | 2004 |
[Treatment of progressive multiple sclerosis with monthly pulsed cyclophosphamide-methylprednisolone: predictive factors of treatment response].
Topics: Adjuvants, Immunologic; Adult; Azathioprine; Brain; Cyclophosphamide; Demography; Drug Therapy, Comb | 2004 |
A patient with multiple sclerosis presenting with Holmes' tremor.
Topics: Adult; Azathioprine; Brain Stem; Cerebellum; Clonazepam; Extremities; Female; GABA Modulators; Human | 2008 |
Current status of multiple sclerosis therapy in Germany: a national survey.
Topics: Adjuvants, Immunologic; Azathioprine; Data Collection; Germany; Humans; Immunosuppressive Agents; Im | 1999 |