azathioprine has been researched along with Chromosome Deletion in 4 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 7.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 3.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| "A boy with microcephaly, unusual facial features, micropenis, and growth retardation was born to a 30-year-old woman who took azathioprine and prednisone before and during pregnancy for systemic lupus erythematosus." | 3.67 | Two chromosome aberrations in the child of a woman with systemic lupus erythematosus treated with azathioprine and prednisone. ( Ostrer, H; Perinchief, P; Stamberg, J, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heredia, F | 1 |
| Sousa, J | 1 |
| Magalhães, S | 1 |
| Pinheiro, R | 1 |
| Ostrer, H | 1 |
| Stamberg, J | 1 |
| Perinchief, P | 1 |
| Krishnan, K | 1 |
| Adams, P | 1 |
| Silveira, S | 1 |
| Sheldon, S | 1 |
| Dabich, L | 1 |
| Vandenberghe, EA | 1 |
| Mecucci, C | 1 |
| Delannoy, A | 1 |
| Van den Berghe, H | 1 |
4 other studies available for azathioprine and Chromosome Deletion
| Article | Year |
|---|---|
Therapy-related myelodysplastic syndrome with 17p deletion following long-term azathioprine treatment.
Topics: Adult; Azathioprine; Chromosome Deletion; Chromosomes, Human, Pair 17; Female; Humans; Myasthenia Gr | 2010 |
Two chromosome aberrations in the child of a woman with systemic lupus erythematosus treated with azathioprine and prednisone.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Azathioprine; Chromosome Aberrations; C | 1984 |
Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis.
Topics: Acute Disease; Azathioprine; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, Pa | 1994 |
Deletion of 5q by t(5;17) in therapy-related myelodysplastic syndrome.
Topics: Adult; Azathioprine; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromosom | 1990 |