azathioprine has been researched along with Chorea Disorders in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A sex-linked familial neurological disease consisting of cerebral palsy, mental retardation, choreoathetosis, and compulsive aggressive behavior is associated with a loss of an enzyme that participates in purine metabolism, namely, hypoxanthine-guanine phosphoribosyltransferase." | 3.64 | Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis. ( Kelley, WN; Rosenbloom, FM; Seegmiller, JE, 1967) |
| "Neurologic complications of systemic lupus erythematosus (SLE) are common, but chorea is rare." | 1.25 | Clinical features of chorea associated with systemic lupus erythematosus. ( Lusins, JO; Szilagyi, PA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seegmiller, JE | 1 |
| Rosenbloom, FM | 1 |
| Kelley, WN | 1 |
| Lusins, JO | 1 |
| Szilagyi, PA | 1 |
| Heilman, KM | 1 |
| Kohler, WC | 1 |
| LeMaster, PC | 1 |
3 other studies available for azathioprine and Chorea Disorders
| Article | Year |
|---|---|
Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Aggression; Athetosis; Azathioprine; Cerebral Palsy | 1967 |
Clinical features of chorea associated with systemic lupus erythematosus.
Topics: Adult; Azathioprine; Blood Sedimentation; Chlorpromazine; Chorea; Female; Haloperidol; Humans; Lupus | 1975 |
Haloperidol treatment of chorea associated with systemic lupus erythematosus.
Topics: Adult; Azathioprine; Chorea; Female; Haloperidol; Humans; Lupus Erythematosus, Systemic | 1971 |