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azathioprine and Cholecystoduodenal Fistula

azathioprine has been researched along with Cholecystoduodenal Fistula in 23 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"To assess the effectiveness of azathioprine and 6-mercaptopurine in inducing remission of active Crohn disease and the effectiveness of azathioprine in maintaining remission of quiescent disease."8.79Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis. ( Fick, GH; May, GR; Pearson, DC; Sutherland, LR, 1995)
"To assess the effectiveness of azathioprine and 6-mercaptopurine in inducing remission of active Crohn disease and the effectiveness of azathioprine in maintaining remission of quiescent disease."4.79Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis. ( Fick, GH; May, GR; Pearson, DC; Sutherland, LR, 1995)
" The patients who achieved a complete remission with medical treatment, who had no history of intestinal perforation, and who received azathioprine after operation showed better clinical courses."3.70Long-term clinical course and prognostic factors in intestinal Behçet's disease. ( Cha, SD; Choi, IJ; Jung, HC; Kim, CY; Kim, JS; Park, JG; Song, IS, 2000)
"Fistulas are common in patients with Crohn's disease and, when associated with inflammatory disease and established for several weeks, tend to be chronic."2.41Management of fistulas in patients with Crohn's disease: antibiotic to antibody. ( Paré, P, 2001)
"Of a total 44 patients with Crohn's disease, 10 patients with 9 internal and 15 external fistulae, some of which were recurrent, were analyzed at the Department of Surgery, Yokohama City University between 1973 and 1988."2.38The medical, nutritional and surgical treatment of fistulae in Crohn's disease. ( Fukushima, T; Sugita, A; Takemura, H; Tsuchiya, S; Yamazaki, Y, 1990)
" Dose intensification to weekly dosing was needed in 16."1.37[Predictors of efficacy, mucosal healing and dose intensification during the first year of adalimumab therapy in patients with luminal and fistulizing Crohn's disease. National data from Hungary]. ( Banai, J; Bartha, Z; Farkas, K; Gasztonyi, B; Golovics, PA; Horváth, G; Kiss, LS; Lakatos, L; Lakatos, PL; Lovász, BD; Miheller, P; Molnár, T; Nagy, F; Palatka, K; Papp, M; Salamon, A; Szamosi, T; Szathmári, M; Szenes, M; Tóth, GT; Tulassay, Z; Végh, Z; Veres, G; Vincze, A, 2011)
"Perianal fistulizing Crohn's disease (PFCD) treatment is based on fistula drainage, antibiotics, immunosuppressant (IS) drugs, and infliximab."1.35Predicting factors of fistula healing and clinical remission after infliximab-based combined therapy for perianal fistulizing Crohn's disease. ( Koning, E; Lerebours, E; Michot, F; Savoye, G; Savoye-Collet, C; Tougeron, D, 2009)
"Prednisone dosage was reduced from a mean of 19."1.32Immunomodulators and "on demand" therapy with infliximab in Crohn's disease: clinical experience with 400 infusions. ( France, R; Kinney, T; Kozarek, R; Patterson, D; Rawlins, M, 2003)
"Azathioprine has been reported to heal fistulas in 30-40% of cases."1.32Combining infliximab and methotrexate in fistulizing Crohn's disease resistant or intolerant to azathioprine. ( Blumenstein, I; Schröder, O; Schulte-Bockholt, A; Stein, J, 2004)
"The rise of fistulae in Crohn's disease has been classed with the disorder complications, although it is a possible component of natural development of the so-called A type (De Dombal classification) or aggressive-perforating type (Greenstein's classification) of this idiopathic intestinal inflammation."1.31Immunosuppressive treatment of Crohn's disease with fistulae. ( Dastych, M; Dite, P; Pazourkova, M; Pokorny, A; Prokopova, L; Zboril, V, 2002)
"Recurrent Crohn's disease and that characterized by small bowel obstruction each displayed a characteristic appearance."1.26Radiographic findings of the National Cooperative Crohn's Disease Study. ( Caruthers, SB; Goldberg, HI; Nelson, JA; Singleton, JW, 1979)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's2 (8.70)18.2507
2000's10 (43.48)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Booth, AT1
Forster, E1
Curran, T1
George, V1
Hoekman, DR1
Stibbe, JA1
Baert, FJ1
Caenepeel, P1
Vergauwe, P1
De Vos, M1
Hommes, DW1
Benninga, MA1
Vermeire, SA1
D'Haens, GR1
Renna, S1
Orlando, A1
Cottone, M1
Tougeron, D1
Savoye, G1
Savoye-Collet, C1
Koning, E1
Michot, F1
Lerebours, E1
Cordero Ruiz, P1
Castro Márquez, C1
Méndez Rufián, V1
Castro Laria, L1
Caunedo Álvarez, A1
Romero Vázquez, J1
Herrerías Gutiérrez, JM1
Kiss, LS1
Szamosi, T1
Molnár, T1
Miheller, P1
Lakatos, L1
Vincze, A1
Palatka, K1
Bartha, Z1
Gasztonyi, B1
Salamon, A1
Horváth, G1
Tóth, GT1
Farkas, K1
Banai, J1
Tulassay, Z1
Nagy, F1
Szenes, M1
Veres, G1
Lovász, BD1
Végh, Z1
Golovics, PA1
Szathmári, M1
Papp, M1
Lakatos, PL1
McCabe, RP1
Chow, CJ1
Rothenberger, DA1
Zboril, V1
Prokopova, L1
Dite, P1
Pokorny, A1
Dastych, M1
Pazourkova, M1
Ochsenkühn, T1
Göke, B1
Sackmann, M1
Aguilera, V1
Calvo, F1
Nos, P1
Molla, A1
Esteban, R1
Ponce, J1
Buhr, HJ1
Kroesen, AJ1
Stange, EF1
Kinney, T1
Rawlins, M1
Kozarek, R1
France, R1
Patterson, D1
Schröder, O1
Blumenstein, I1
Schulte-Bockholt, A1
Stein, J1
Treepongkaruna, S1
Pienvichit, P1
Sornmayura, P1
Pornkul, R1
Wisedopas, N1
Phuapradit, P1
Pearson, DC1
May, GR1
Fick, GH1
Sutherland, LR1
Choi, IJ1
Kim, JS1
Cha, SD1
Jung, HC1
Park, JG1
Song, IS1
Kim, CY1
Paré, P1
Goldberg, HI1
Caruthers, SB1
Nelson, JA1
Singleton, JW1
Yamazaki, Y1
Fukushima, T1
Sugita, A1
Takemura, H1
Tsuchiya, S1
Brooke, BN1
Javett, SL1
Davison, OW1
Fahrländer, H1
Shalev, E1
Williams, JA1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Anti-TNF Antibodies on the T-lymphocyte and Macrophage Cooperation in the Crohn Disease[NCT00561548]20 participants (Anticipated)Interventional2007-05-31Terminated
Fibrin Glue for Perianal Fistulas in Crohn's Disease: a Randomized Controlled Trial[NCT00723047]Phase 377 participants (Actual)Interventional2003-11-30Completed
Treatment of Fistulous Crohn's Disease by Implant of Autologous Mesenchymal Stem Cells Derived From Adipose Tissue[NCT01157650]Phase 1/Phase 215 participants (Actual)Interventional2010-06-30Completed
A Prospective Longitudinal Study on the Effect of Tight Control Management on Perianal Crohn's Disease[NCT03861689]40 participants (Anticipated)Interventional2019-07-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for azathioprine and Cholecystoduodenal Fistula

ArticleYear
Comparing medical treatments for Crohn's disease.
    Journal of comparative effectiveness research, 2013, Volume: 2, Issue:2

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Bacterial Agents; Azathioprine; Biological Facto

2013
[Sciatica secondary to a presacral abscess as the first manifestation of Crohn's disease].
    Gastroenterologia y hepatologia, 2002, Volume: 25, Issue:8

    Topics: Abscess; Adult; Azathioprine; Combined Modality Therapy; Crohn Disease; Drug Therapy, Combination; E

2002
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.
    Annals of internal medicine, 1995, Jul-15, Volume: 123, Issue:2

    Topics: Azathioprine; Crohn Disease; Drug Administration Schedule; Humans; Intestinal Fistula; Mercaptopurin

1995
Management of fistulas in patients with Crohn's disease: antibiotic to antibody.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2001, Volume: 15, Issue:11

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Azathioprine; Colonic Diseases; Crohn Disease; Cyclos

2001
The medical, nutritional and surgical treatment of fistulae in Crohn's disease.
    The Japanese journal of surgery, 1990, Volume: 20, Issue:4

    Topics: Adult; Azathioprine; Colonic Diseases; Combined Modality Therapy; Crohn Disease; Enteral Nutrition;

1990
The place of surgery in Crohn's disease.
    Gut, 1971, Volume: 12, Issue:9

    Topics: Abscess; Acute Disease; Anemia; Appendectomy; Azathioprine; Colectomy; Colonic Diseases; Crohn Disea

1971

Trials

2 trials available for azathioprine and Cholecystoduodenal Fistula

ArticleYear
Long-term Outcome of Early Combined Immunosuppression Versus Conventional Management in Newly Diagnosed Crohn's Disease.
    Journal of Crohn's & colitis, 2018, Apr-27, Volume: 12, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biological Products; Colonoscopy; Crohn Disease; Drug

2018
Efficacy of adalimumab in patients with Crohn's disease and failure to infliximab therapy: a clinical series.
    Revista espanola de enfermedades digestivas, 2011, Volume: 103, Issue:6

    Topics: Abdominal Abscess; Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclo

2011

Other Studies

15 other studies available for azathioprine and Cholecystoduodenal Fistula

ArticleYear
Gastrocolic Fistula Involving the Pancreas in a Patient With Crohn's Disease.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:11

    Topics: Adalimumab; Azathioprine; Budesonide; Colectomy; Colitis; Crohn Disease; Gastric Fistula; Humans; Il

2019
Predicting factors of fistula healing and clinical remission after infliximab-based combined therapy for perianal fistulizing Crohn's disease.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Ciprof

2009
[Predictors of efficacy, mucosal healing and dose intensification during the first year of adalimumab therapy in patients with luminal and fistulizing Crohn's disease. National data from Hungary].
    Orvosi hetilap, 2011, Sep-04, Volume: 152, Issue:36

    Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humaniz

2011
Duodenal-pleural fistula in Crohn's disease: successful long-term medical management.
    Inflammatory bowel diseases, 2013, Volume: 19, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Crohn Disease; Drug Therapy, Combination; Duodenal Dise

2013
Immunosuppressive treatment of Crohn's disease with fistulae.
    Bratislavske lekarske listy, 2002, Volume: 103, Issue:3

    Topics: Adult; Azathioprine; Crohn Disease; Cutaneous Fistula; Cyclosporine; Drug Therapy, Combination; Fema

2002
Combining infliximab with 6-mercaptopurine/azathioprine for fistula therapy in Crohn's disease.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:8

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Crohn Disease; Drug Therapy, Combination; Female; Gastr

2002
[Surgery -- fistulas].
    Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:1

    Topics: Abdominal Abscess; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal; Azathiopr

2003
Immunomodulators and "on demand" therapy with infliximab in Crohn's disease: clinical experience with 400 infusions.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Crohn Disease; Drug Therapy,

2003
Combining infliximab and methotrexate in fistulizing Crohn's disease resistant or intolerant to azathioprine.
    Alimentary pharmacology & therapeutics, 2004, Feb-01, Volume: 19, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Crohn Disease; Drug Evaluation; Drug Resistance; Drug T

2004
Inflammatory bowel disease in Thai children: presentations and outcomes of treatment.
    Asian Pacific journal of allergy and immunology, 2006, Volume: 24, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Child; C

2006
Long-term clinical course and prognostic factors in intestinal Behçet's disease.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Behcet Syndrome; Colectomy; Colonic Diseases; Colonoscopy; Combined

2000
Radiographic findings of the National Cooperative Crohn's Disease Study.
    Gastroenterology, 1979, Volume: 77, Issue:4 Pt 2

    Topics: Adult; Age Factors; Azathioprine; Colon; Crohn Disease; Duodenum; Female; Humans; Ileum; Intestinal

1979
Further experience with azathioprine for Crohn's disease.
    Lancet (London, England), 1970, Nov-21, Volume: 2, Issue:7682

    Topics: Adolescent; Adult; Azathioprine; Crohn Disease; Female; Humans; Intestinal Fistula; Klebsiella Infec

1970
[Regional enteritis (Crohn's disease). A follow-up and comparative study of 182 patients (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Nov-01, Volume: 99, Issue:44

    Topics: Adolescent; Adult; Age Factors; Aged; Azathioprine; Child; Child, Preschool; Crohn Disease; Erythema

1974
Azathioprine in Crohn's disease.
    Drug and therapeutics bulletin, 1973, Aug-31, Volume: 11, Issue:18

    Topics: Azathioprine; Crohn Disease; Humans; Intestinal Fistula; Leukopenia; Nausea

1973