Page last updated: 2024-10-23

azathioprine and Cholangitis

azathioprine has been researched along with Cholangitis in 24 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.

Research Excerpts

ExcerptRelevanceReference
"In this case, the combination of steroids with tacrolimus seems to be a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis."7.80Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis. ( Buechter, M; Canbay, A; Gerken, G; Kahraman, A; Klein, CG; Kloeters, C; Schlaak, JF, 2014)
"In this case, the combination of steroids with tacrolimus seems to be a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis."3.80Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis. ( Buechter, M; Canbay, A; Gerken, G; Kahraman, A; Klein, CG; Kloeters, C; Schlaak, JF, 2014)
"Autoimmune cholangitis is a rare chronic cholestatic liver disease."2.40Autoimmune cholangitis in a patient with celiac disease: a case report and review of the literature. ( Gogos, CA; Nikolopoulou, V; Siampi, V; Vagenakis, A; Zolota, V, 1999)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's4 (16.67)18.2507
2000's3 (12.50)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saffioti, F1
Gurusamy, KS1
Eusebi, LH1
Tsochatzis, E1
Davidson, BR1
Thorburn, D1
Di Giorgio, A1
D'Adda, A1
Marseglia, A1
Sonzogni, A1
Licini, L1
Nicastro, E1
D'Antiga, L1
Vinokurova, LV1
Dubtsova, EA1
Bystrovskaia, EV1
Orlova, IuN1
Agafonov, MA1
Vainer, E1
Vainer, G1
Jacob, H1
Faroja, M1
Buechter, M1
Klein, CG1
Kloeters, C1
Schlaak, JF1
Canbay, A1
Gerken, G1
Kahraman, A1
Sandanayake, NS1
Church, NI1
Chapman, MH1
Johnson, GJ1
Dhar, DK1
Amin, Z1
Deheragoda, MG1
Novelli, M1
Winstanley, A1
Rodriguez-Justo, M1
Hatfield, AR1
Pereira, SP1
Webster, GJ1
Czaja, AJ1
Muratori, P1
Muratori, L1
Carpenter, HA1
Bianchi, FB1
Spence, RA1
Anderson, JR1
Johnston, GW1
Fulton, TT1
Callender, ME1
Taylor, SL1
Dean, PJ1
Riely, CA1
Sánchez-Pobre, P1
Castellano, G1
Colina, F1
Dominguez, P1
Rodriguez, S1
Canga, F1
Herruzo, JA1
Langrehr, JM1
Glanemann, M1
Guckelberger, O1
Klupp, J1
Neumann, U1
Machens, C1
Lohmann, R1
Knoop, M1
Lobeck, H1
Schlag, H1
Keck, H1
Settmacher, U1
Bechstein, WO1
Neuhaus, PJ1
Gogos, CA1
Nikolopoulou, V1
Zolota, V1
Siampi, V1
Vagenakis, A1
Sobesky, R1
Dusoleil, A1
Condat, B1
Bedossa, P1
Buffet, C1
Pelletier, G1
Cello, JP1
Geubel, AP1
Baggenstoss, AH2
Summerskill, WH2
Brunner, G1
Mendel, R1
Hebestreit, HP1
Droste, R1
Bade, J1
Georgi, M1
Javett, SL1
Wagner, A1
Pagaltsos, AP1
Smith, MG1
Eddleston, AL1
Williams, R1
Gips, CH1
MacSween, RN1
Soloway, RD1
Elveback, LR1
Schoenfield, LJ1
Reuber, MD1

Reviews

2 reviews available for azathioprine and Cholangitis

ArticleYear
Pharmacological interventions for primary biliary cholangitis: an attempted network meta-analysis.
    The Cochrane database of systematic reviews, 2017, 03-28, Volume: 3

    Topics: Azathioprine; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Chronic Disease; Colc

2017
Autoimmune cholangitis in a patient with celiac disease: a case report and review of the literature.
    Journal of hepatology, 1999, Volume: 30, Issue:2

    Topics: Aged; Autoimmune Diseases; Azathioprine; Celiac Disease; Cholangitis; Drug Therapy, Combination; Fem

1999

Trials

3 trials available for azathioprine and Cholangitis

ArticleYear
Diagnostic and therapeutic implications of bile duct injury in autoimmune hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2004, Volume: 24, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Autoantibodies; Azathioprine; Bile Ducts; Cell Nucleus; Cholangitis;

2004
A randomized, placebo-controlled trial with anti-interleukin-2 receptor antibody for immunosuppressive induction therapy after liver transplantation.
    Clinical transplantation, 1998, Volume: 12, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibodies, Monoclonal; Azathioprine; Cholangitis; Cyclospor

1998
Chronic active liver disease. The range of histologic lesions, their response to treatment, and evolution.
    Human pathology, 1972, Volume: 3, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Autopsy; Azathioprine; Biopsy; Cholangitis; Chronic Disease;

1972

Other Studies

19 other studies available for azathioprine and Cholangitis

ArticleYear
Biliary features in liver histology of children with autoimmune liver disease.
    Hepatology international, 2019, Volume: 13, Issue:4

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Cholangitis; Cholangitis, Sclerosing; Drug Therap

2019
[Diagnostic difficulties and remission criteria of autoimmune pancreatitis].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:2

    Topics: Autoimmune Diseases; Azathioprine; Cholangitis; Female; Humans; Immunosuppressive Agents; Middle Age

2013
Eosinophilic cholangitis diagnosed endoscopically.
    Endoscopy, 2014, Volume: 46 Suppl 1 UCTN

    Topics: Adolescent; Anti-Inflammatory Agents; Azathioprine; Cholangiopancreatography, Endoscopic Retrograde;

2014
Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis.
    Zeitschrift fur Gastroenterologie, 2014, Volume: 52, Issue:6

    Topics: Aged; Azathioprine; Cholangitis; Drug Therapy, Combination; Humans; Immunoglobulin G; Immunosuppress

2014
Presentation and management of post-treatment relapse in autoimmune pancreatitis/immunoglobulin G4-associated cholangitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2009, Volume: 7, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Autoimmune Diseases; Azathioprine; Cholang

2009
Primary sclerosing cholangitis.
    The Ulster medical journal, 1984, Volume: 53, Issue:1

    Topics: Adult; Aged; Azathioprine; Cholangitis; Cholestyramine Resin; Drainage; Female; Humans; Male; Middle

1984
Primary autoimmune cholangitis. An alternative to antimitochondrial antibody-negative primary biliary cirrhosis.
    The American journal of surgical pathology, 1994, Volume: 18, Issue:1

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Azathioprine; Biopsy; Cho

1994
Antimitochondrial antibody-negative chronic nonsuppurative destructive cholangitis. Atypical primary biliary cirrhosis or autoimmune cholangitis?
    Journal of clinical gastroenterology, 1996, Volume: 23, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Autoantibodies; Autoimmune Diseases; Azathioprine; Cholangitis; Cyc

1996
Azathioprine-induced destructive cholangitis.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:2

    Topics: Azathioprine; Bile Ducts, Intrahepatic; Cholangitis; Humans; Immunosuppressive Agents; Liver; Male;

2001
Cholestasis in ulcerative colitis. Long term complications and medical therapy.
    Gastroenterology, 1977, Volume: 73, Issue:2

    Topics: Anti-Bacterial Agents; Azathioprine; Bacterial Infections; Bile Acids and Salts; Cholangitis; Cholel

1977
Responses to treatment can differentiate chronic active liver disease with cholangitic features from the primary biliary cirrhosis syndrome.
    Gastroenterology, 1976, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Azathioprine; Cholangitis; Chronic Disease; Drug Admin

1976
[Therapy of the chronic destructive, non-purulent cholangitis (primary biliary cirrhosis)].
    Deutsche medizinische Wochenschrift (1946), 1976, Sep-03, Volume: 101, Issue:36

    Topics: Azathioprine; Calcium; Cholangitis; Cholestyramine Resin; Clofibrate; Humans; Hypercholesterolemia;

1976
[2 cases of primary sclerosing cholangitis--the ERCP documentation of a 3-year course of immunosuppressive therapy].
    Der Radiologe, 1985, Volume: 25, Issue:2

    Topics: Adult; Azathioprine; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Cholestasis, Intr

1985
Azathioprine in primary sclerosing cholangitif.
    Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703

    Topics: Azathioprine; Bile Ducts; Cholangiography; Cholangitis; Female; Humans; Middle Aged

1971
Azathioprine treatment in primary sclerosing cholangitis.
    Lancet (London, England), 1971, Sep-18, Volume: 2, Issue:7725

    Topics: Acute Kidney Injury; Autopsy; Azathioprine; Bilirubin; Cholangitis; Humans; Liver Abscess; Male; Mid

1971
Total haemolytic complement after liver transplantation and in liver disease.
    Transplantation, 1972, Volume: 14, Issue:1

    Topics: Acute Disease; Adult; Aspartate Aminotransferases; Azathioprine; Bilirubin; Carcinoma, Hepatocellula

1972
Reflections on the treatment of itch in primary biliary cirrhosis.
    The Netherlands journal of medicine, 1973, Volume: 16, Issue:3

    Topics: Adult; Azathioprine; Child, Preschool; Cholangitis; Cholestyramine Resin; Female; Humans; Phenobarbi

1973
Hepatic sepsis after liver transplantation in dogs and pigs.
    Archives of pathology, 1969, Volume: 88, Issue:2

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Cholangitis; Dogs; Immunosuppressive Agents; Infections

1969
Accentuation of carbon tetrachloride-induced cirrhosis by azathioprine in the rat.
    Archives of pathology, 1970, Volume: 90, Issue:6

    Topics: Animals; Azathioprine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chola

1970