azathioprine has been researched along with Cholangiocellular Carcinoma in 6 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine has been associated with an increased risk for malignancy, therefore we investigated whether azathioprine use affects the risk of CCA in persons with PSC." | 5.43 | No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis. ( Boberg, KM; Bubenheim, M; Ehlken, H; Hartl, J; Hübener, P; Hübener, S; Jørgensen, KK; Karlsen, TH; Lenzen, H; Lohse, AW; Manns, MP; Pannicke, N; Peiseler, M; Schramm, C; Schulze, K; Sebode, M; Weiler-Normann, C; Weismüller, TJ; Zenouzi, R, 2016) |
| "Azathioprine has been associated with an increased risk for malignancy, therefore we investigated whether azathioprine use affects the risk of CCA in persons with PSC." | 1.43 | No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis. ( Boberg, KM; Bubenheim, M; Ehlken, H; Hartl, J; Hübener, P; Hübener, S; Jørgensen, KK; Karlsen, TH; Lenzen, H; Lohse, AW; Manns, MP; Pannicke, N; Peiseler, M; Schramm, C; Schulze, K; Sebode, M; Weiler-Normann, C; Weismüller, TJ; Zenouzi, R, 2016) |
| " There was no increase in concurrent immunosuppressives dosage after the conversion." | 1.29 | Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation. ( Kaplan, MM; Pedrosa, MC; Rohrer, RM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Creutzfeldt, AM | 1 |
| Piecha, F | 1 |
| Schattenberg, JM | 1 |
| Schramm, C | 2 |
| Lohse, AW | 2 |
| Zenouzi, R | 1 |
| Weismüller, TJ | 1 |
| Jørgensen, KK | 1 |
| Bubenheim, M | 1 |
| Lenzen, H | 1 |
| Hübener, P | 1 |
| Schulze, K | 1 |
| Weiler-Normann, C | 1 |
| Sebode, M | 1 |
| Ehlken, H | 1 |
| Pannicke, N | 1 |
| Hartl, J | 1 |
| Peiseler, M | 1 |
| Hübener, S | 1 |
| Karlsen, TH | 1 |
| Boberg, KM | 1 |
| Manns, MP | 1 |
| Maggs, J | 1 |
| Cullen, S | 1 |
| Gómez, V | 1 |
| Michel, JA | 1 |
| Pedrosa, MC | 1 |
| Rohrer, RM | 1 |
| Kaplan, MM | 1 |
| Broomé, U | 1 |
| Glaumann, H | 1 |
| Lindstöm, E | 1 |
| Lööf, L | 1 |
| Almer, S | 1 |
| Prytz, H | 1 |
| Sandberg-Gertzén, H | 1 |
| Lindgren, S | 1 |
| Fork, FT | 1 |
| Järnerot, G | 1 |
| Olsson, R | 1 |
1 review available for azathioprine and Cholangiocellular Carcinoma
| Article | Year |
|---|---|
Management of autoimmune liver disease.
Topics: Autoantibodies; Azathioprine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellul | 2009 |
5 other studies available for azathioprine and Cholangiocellular Carcinoma
| Article | Year |
|---|---|
Long-term outcome in PSC patients receiving azathioprine: Does immunosuppression have a positive effect on survival?
Topics: Adult; Azathioprine; Bile Ducts; Cholangiocarcinoma; Cholangitis, Sclerosing; Disease Progression; F | 2020 |
No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis.
Topics: Adult; Azathioprine; Cholangiocarcinoma; Cholangitis, Sclerosing; Female; Germany; Humans; Immunosup | 2016 |
The great mimicker.
Topics: Aged; Autoimmune Diseases; Azathioprine; Biopsy; Cholangiocarcinoma; Diagnosis, Differential; Female | 2012 |
Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarc | 1995 |
Natural history and outcome in 32 Swedish patients with small duct primary sclerosing cholangitis (PSC).
Topics: Adolescent; Adult; Aged; Antimetabolites; Azathioprine; Bile Duct Neoplasms; Bile Ducts, Extrahepati | 2002 |